Strain Name:
C57BL/6J-MtgxR0798Btlr/Mmmh
Stock Number:
038978-MU
Citation ID:
RRID:MMRRC_038978-MU
Other Names:
R0798 (G1), C57BL/6J-MtgxR0798Btlr
Major Collection:

Strain Information

Bcar3
Name: breast cancer anti-estrogen resistance 3
Synonyms: AND-34
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 29815
HGNC: HGNC:973
Homologene: 31181
Lpp
Name: LIM domain containing preferred translocation partner in lipoma
Synonyms: 9430020K16Rik, B130055L10Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 210126
VEGA: 16
HGNC: HGNC:6679
Homologene: 4075
Zmym6
Name: zinc finger, MYM-type 6
Synonyms: Zfp258, 9330177P20Rik, D4Wsu24e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100177
Homologene: 5186
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: Walp3, C030005G16Rik, Tip5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Utp4
Name: UTP4 small subunit processome component
Synonyms: Tex292, TEG-292, Cirh1a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 21771
HGNC: HGNC:1983
Homologene: 40775
Samd4b
Name: sterile alpha motif domain containing 4B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233033
Homologene: 35268
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F37S1, D7H15F32S1, rjs, jdf2, D15F32S1h
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Tasor
Name: transcription activation suppressor
Synonyms: Fam208a, D14Abb1e, 4933409E02Rik, MommeD6
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218850
VEGA: 14
Homologene: 9062
Cmas
Name: cytidine monophospho-N-acetylneuraminic acid synthetase
Synonyms: CMP-sialic acid synthetase, D6Bwg0250e, CMP-Neu5Ac synthase
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12764
Homologene: 7670
Slc39a11
Name: solute carrier family 39 (metal ion transporter), member 11
Synonyms: 1810074D23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69806
Homologene: 12331
Ptp4a1
Name: protein tyrosine phosphatase 4a1
Synonyms: Prl-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19243
HGNC: HGNC:9634
Homologene: 2587
Rab23
Name: RAB23, member RAS oncogene family
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19335
Homologene: 7503
Ubr2
Name: ubiquitin protein ligase E3 component n-recognin 2
Synonyms: ENSMUSG00000043296, 9930021A08Rik, E130209G04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224826
VEGA: 17
Homologene: 26151
Shisa4
Name: shisa family member 4
Synonyms: Tmem58, 9330132O05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 77552
Homologene: 18428
Crppa
Name: CDP-L-ribitol pyrophosphorylase A
Synonyms: 4930579E17Rik, Ispd
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75847
VEGA: 12
Homologene: 45614
Nlgn1
Name: neuroligin 1
Synonyms: 6330415N05Rik, NL1, Nlg1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192167
Homologene: 56690
C130074G19Rik
Name: RIKEN cDNA C130074G19 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226777
Homologene: 11669
CAAA01180111.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Plekhn1
Name: pleckstrin homology domain containing, family N member 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 231002
VEGA: 4
Homologene: 12949
Myo5c
Name: myosin VC
Synonyms: 9130003O20Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208943
VEGA: 9
HGNC: HGNC:7604
Homologene: 135711
Gopc
Name: golgi associated PDZ and coiled-coil motif containing
Synonyms: 2210402P09Rik, GOPC1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 94221
VEGA: 10
Homologene: 10695
Or7e178
Name: olfactory receptor family 7 subfamily E member 178
Synonyms: MTPCR34, Olfr18, GA_x6K02T2PVTD-14054886-14053957, MOR145-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18315
HGNC: HGNC:8396
Homologene: 138313
Cyp3a25
Name: cytochrome P450, family 3, subfamily a, polypeptide 25
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56388
Homologene: 135775
Iqca1
Name: IQ motif containing with AAA domain 1
Synonyms: Iqca, 4930585L22Rik, 4930465P12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74918
Homologene: 49784
Tas1r2
Name: taste receptor, type 1, member 2
Synonyms: T1r2, TR2, Gpr71
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 83770
Homologene: 75323
4930579C12Rik
Name: RIKEN cDNA 4930579C12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319213
Kcnq5
Name: potassium voltage-gated channel, subfamily Q, member 5
Synonyms: D1Mgi1, 9230107O05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226922
HGNC: HGNC:6299
Homologene: 28270
Or4k38
Name: olfactory receptor family 4 subfamily K member 38
Synonyms: GA_x6K02T2Q125-72387537-72386620, Olfr1557, MOR248-2, Olfr1282, MOR248-16
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258909
Homologene: 73992
Tial1
Name: Tia1 cytotoxic granule-associated RNA binding protein-like 1
Synonyms: mTIAR, TIAR, 5330433G13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21843
Homologene: 87796
Vmn1r212
Name: vomeronasal 1 receptor 212
Synonyms: V1rh18
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171275
Homologene: 110880
Ly6g6e
Name: lymphocyte antigen 6 family member G6E
Synonyms: 2310011I02Rik, G6e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 70274
Homologene: 41553
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 21,961,175 bp
  • A to T, chromosome 1 at 30,944,924 bp
  • A to T, chromosome 1 at 33,734,827 bp
  • C to A, chromosome 1 at 90,142,731 bp
  • G to A, chromosome 1 at 135,373,148 bp
  • G to A, chromosome 1 at 184,882,676 bp
  • T to C, chromosome 2 at 111,335,344 bp
  • A to G, chromosome 3 at 25,434,246 bp
  • T to C, chromosome 3 at 122,525,299 bp
  • C to T, chromosome 4 at 127,103,523 bp
  • T to C, chromosome 4 at 139,669,713 bp
  • T to A, chromosome 4 at 156,228,263 bp
  • T to C, chromosome 5 at 145,991,533 bp
  • T to C, chromosome 6 at 142,764,656 bp
  • G to A, chromosome 7 at 28,401,623 bp
  • T to A, chromosome 7 at 56,135,683 bp
  • C to T, chromosome 7 at 128,443,878 bp
  • T to C, chromosome 8 at 106,922,226 bp
  • A to T, chromosome 9 at 20,314,199 bp
  • T to C, chromosome 9 at 75,257,984 bp
  • T to A, chromosome 9 at 89,152,827 bp
  • T to C, chromosome 9 at 124,295,159 bp
  • C to T, chromosome 10 at 52,358,811 bp
  • T to A, chromosome 10 at 128,126,323 bp
  • C to T, chromosome 11 at 113,523,504 bp
  • G to A, chromosome 12 at 36,521,999 bp
  • T to C, chromosome 13 at 22,883,698 bp
  • T to A, chromosome 14 at 27,476,636 bp
  • G to T, chromosome 16 at 24,971,872 bp
  • T to C, chromosome 17 at 35,078,041 bp
  • C to T, chromosome 17 at 46,969,176 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0798 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038978-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.