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Homozygous: ER reporter gene phenotype for homozygous mice is ~twice the expression of the heterozygous mice
Hemizygous: ER reporter gene phenotype for homozygous mice is ~twice the expression of the heterozygous mice
Nagel SC, Hagelbarger JL, McDonnell DP. Development of an ER Action Indicator Mouse for the Study of Estrogens, Selective ER Modulators (SERMs), and Xenobiotics. Endocrinology. 2001 Nov;142(11):4721-8.(Medline PMID: 11606437)
Colony Surveillance Program and Current Health Reports
Backcross or Sib-mating
Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.
Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.