Strain Name:
C57BL/6J-MtgxR5929Btlr/Mmmh
Stock Number:
044124-MU
Citation ID:
RRID:MMRRC_044124-MU
Other Names:
R5929 (G1)
Major Collection:

Strain Information

Gabra6
Name: gamma-aminobutyric acid type A receptor subunit alpha 6
Synonyms: Gabra-6, alpha6, GABA-ARalpha6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14399
HGNC: HGNC:4080
Homologene: 20220
Mtmr7
Name: myotubularin related protein 7
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 54384
HGNC: HGNC:7454
Homologene: 99732
Xpnpep1
Name: X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Synonyms: D230045I08Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 170750
Homologene: 6424
Sema3f
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
Synonyms: Sema IV, Semak
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20350
Homologene: 20885
Paip1
Name: polyadenylate binding protein-interacting protein 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218693
Homologene: 4709
Psmd3
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
Synonyms: AntP91a, Psd3, Tstap91a
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22123
HGNC: HGNC:9560
Homologene: 2102
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 277854
Homologene: 34718
Ankib1
Name: ankyrin repeat and IBR domain containing 1
Synonyms: 2310061P20Rik, 4631416I11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70797
Homologene: 19076
Kifbp
Name: kinesin family binding protein
Synonyms: 2510003E04Rik, Kif1bp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 72320
Homologene: 9223
Phkb
Name: phosphorylase kinase beta
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102093
HGNC: HGNC:8927
Homologene: 247
Plcg1
Name: phospholipase C, gamma 1
Synonyms: Plc-1, Plcg-1, Plc-gamma1, Cded
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18803
HGNC: HGNC:9065
Homologene: 1997
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: P400, IP3R1, Itpr-1, Ip3r, Pcp-1, opt, InsP3R type I, Pcp1, wblo
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Dcaf13
Name: DDB1 and CUL4 associated factor 13
Synonyms: LOC223499, Wdsof1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223499
Homologene: 6430
Gcfc2
Name: GC-rich sequence DNA binding factor 2
Synonyms: AW146020
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330361
HGNC: HGNC:1317
Homologene: 2411
Tlr7
Name: toll-like receptor 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 170743
Homologene: 75060
Dsp
Name: desmoplakin
Synonyms: 2300002E22Rik, DP, 5730453H04Rik, rul
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Casz1
Name: castor zinc finger 1
Synonyms: 2410019P08Rik, D4Ertd432e, castor, Cst
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69743
Homologene: 9824
Olfm3
Name: olfactomedin 3
Synonyms: optimedin, B230206G02Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229759
Homologene: 17103
Chordc1
Name: cysteine and histidine rich domain containing 1
Synonyms: 1110001O09Rik, Chp-1, morgana
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66917
VEGA: 9
Homologene: 8111
Wrnip1
Name: Werner helicase interacting protein 1
Synonyms: WHIP, 4833444L21Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 78903
Homologene: 10592
Pcdhb18
Name: protocadherin beta 18
Synonyms: Pcdhb9, PcdhbR
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93889
Homologene: 137649
Tspan12
Name: tetraspanin 12
Synonyms: Tm4sf12
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 269831
Homologene: 8212
Gpr155
Name: G protein-coupled receptor 155
Synonyms: DEPDC3, PGR22, 1110017O10Rik, F730029F15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68526
Homologene: 16584
Mapk3
Name: mitogen-activated protein kinase 3
Synonyms: Erk-1, p44 MAP kinase, p44erk1, p44mapk, Prkm3, Erk1, Esrk1, Mtap2k
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26417
HGNC: HGNC:6877
Homologene: 55682
Ginm1
Name: glycoprotein integral membrane 1
Synonyms: BC013529
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215751
Homologene: 16347
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Mdnah5, b2b1154Clo, b2b1134Clo, b2b1537Clo, b2b1565Clo, Dnahc5, b2b3491Clo
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Kif27
Name: kinesin family member 27
Synonyms: 4930517I18Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75050
VEGA: 13
Homologene: 69235
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545370
Homologene: 23741
Slc35b2
Name: solute carrier family 35, member B2
Synonyms: 1110003M08Rik, PAPST1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 73836
VEGA: 17
Homologene: 24504
Cd244a
Name: CD244 molecule A
Synonyms: 2B4, C9.1, Nmrk, F730046O15Rik, Cd244
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18106
Homologene: 9493
Ang4
Name: angiogenin, ribonuclease A family, member 4
Synonyms: Rnase5d
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219033
HGNC: HGNC:483
Homologene: 135633
Rims1
Name: regulating synaptic membrane exocytosis 1
Synonyms: RIM1, RIM1a, C030033M19Rik, RIM1alpha
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 116837
Homologene: 128399
Prg4
Name: proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
Synonyms: MSF, DOL54, lubricin, SZP
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 96875
HGNC: HGNC:9364
Homologene: 137352
Mogat1
Name: monoacylglycerol O-acyltransferase 1
Synonyms: 0610030A14Rik, mDC2, MGAT1, Dgat2l1, 1110064N14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68393
Homologene: 105237
Shoc1
Name: shortage in chiasmata 1
Synonyms: LOC242489, Gm426, AI481877, Mzip2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100155
Homologene: 79783
Col4a1
Name: collagen, type IV, alpha 1
Synonyms: Col4a-1, Del(8)Bru44H, Del(8)44H, Bru, Svc, Raw, alpha1(IV) collagen
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12826
HGNC: HGNC:2202
Homologene: 20437
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: EG235580, 1110001D15Rik, Dvwa, Vwa6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68553
Homologene: 130754
Lhcgr
Name: luteinizing hormone/choriogonadotropin receptor
Synonyms: Lhr, Gpcr19-rs1, LH-R
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16867
VEGA: 17
HGNC: HGNC:6585
Homologene: 37276
Padi2
Name: peptidyl arginine deiminase, type II
Synonyms: PAD type II, Pdi, Pdi2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18600
Homologene: 7214
Odad3
Name: outer dynein arm docking complex subunit 3
Synonyms: Ccdc151, C330001K17Rik, b2b1885Clo
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77609
VEGA: 9
Homologene: 16533
Fyn
Name: Fyn proto-oncogene
Synonyms: Src Kinase p59
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14360
HGNC: HGNC:4037
Homologene: 48068
Ankrd1
Name: ankyrin repeat domain 1
Synonyms: CARP, Alrp, Crap, MARP1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107765
VEGA: 19
Homologene: 8289
Zup1
Name: zinc finger containing ubiquitin peptidase 1
Synonyms: 2700019D07Rik, Zufsp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 72580
VEGA: 10
Homologene: 12472
Hdac3
Name: histone deacetylase 3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 15183
HGNC: HGNC:4854
Homologene: 48250
Ccdc83
Name: coiled-coil domain containing 83
Synonyms: 4930549K11Rik, 4930554C01Rik, 4932423M01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75338
Homologene: 32709
Kif21b
Name: kinesin family member 21B
Synonyms: N-5 kinesin, 2610511N21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16565
Homologene: 56868
Nfe2l1
Name: nuclear factor, erythroid derived 2,-like 1
Synonyms: TCF-11, NRF1, LCR-F1, TCF11, Lcrf1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18023
HGNC: HGNC:7781
Homologene: 20685
Car6
Name: carbonic anhydrase 6
Synonyms: DOC1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12353
HGNC: HGNC:1380
Homologene: 20324
Ces3b
Name: carboxylesterase 3B
Synonyms: ES31L, Gm4738
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13909
HGNC: HGNC:1865
Homologene: 84407
Gm19345
Name: predicted gene, 19345
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100502736
Ipo4
Name: importin 4
Synonyms: 8430408O15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75751
Homologene: 5835
Prss3
Name: serine protease 3
Synonyms: Tb, TRY4, MTG, mesotrypsin, Try3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22073
Homologene: 88408
Cr2
Name: complement receptor 2
Synonyms: CD21, CD35, Cr-1, Cr-2, Cr1, C3DR
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12902
HGNC: HGNC:2336
Homologene: 55611
Pak1ip1
Name: PAK1 interacting protein 1
Synonyms: 5830431I15Rik, 5930415H02Rik, p21-activated protein kinase-interacting protein 1, PIP1, Gdpd1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68083
Homologene: 39574
Catsperd
Name: cation channel sperm associated auxiliary subunit delta
Synonyms: 4933402B14Rik, Gm6095, 4921529N20Rik, Tmem146
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106757
VEGA: 17
Homologene: 51896
Kif12
Name: kinesin family member 12
Synonyms: N-9 kinesin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16552
Homologene: 7796
Lrrc8d
Name: leucine rich repeat containing 8D
Synonyms: 4930525N13Rik, Lrrc5, 2810473G09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231549
Homologene: 10004
Cd163
Name: CD163 antigen
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 93671
HGNC: HGNC:1631
Homologene: 128811
Hacl1
Name: 2-hydroxyacyl-CoA lyase 1
Synonyms: Hpcl, 1600020H07Rik, Phyh2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56794
Homologene: 5794
Stx5a
Name: syntaxin 5A
Synonyms: syntaxin 5, 0610031F24Rik, D19Ertd627e
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56389
Homologene: 2381
Utp11
Name: UTP11 small subunit processome component
Synonyms: 2700082D03Rik, Utp11l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67205
Homologene: 6349
Ndufaf6
Name: NADH:ubiquinone oxidoreductase complex assembly factor 6
Synonyms: 2310030N02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76947
Homologene: 43831
Casd1
Name: CAS1 domain containing 1
Synonyms: Cast1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213819
Homologene: 11287
Zfp354b
Name: zinc finger protein 354B
Synonyms: Kid2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 27274
Homologene: 32187
Otub1
Name: OTU domain, ubiquitin aldehyde binding 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107260
Homologene: 9772
Dnajc5b
Name: DnaJ heat shock protein family (Hsp40) member C5 beta
Synonyms: 1700008A05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66326
Homologene: 32634
Sox12
Name: SRY (sex determining region Y)-box 12
Synonyms: 2010205A02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20667
Homologene: 5057
Or4f7d-ps1
Name: olfactory receptor family 4 subfamily F member 7D, pseudogene 1
Synonyms: GA_x6K02T2N82Q-12713-13766, MOR245-17P, Gm13931, Olfr268-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668825
Homologene: 138901
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 22,468,241 bp
  • A to T, chromosome 1 at 78,523,733 bp
  • A to G, chromosome 1 at 136,151,207 bp
  • A to G, chromosome 1 at 150,454,129 bp
  • C to A, chromosome 1 at 150,577,296 bp
  • A to T, chromosome 1 at 171,559,367 bp
  • A to G, chromosome 1 at 195,171,111 bp
  • G to A, chromosome 2 at 73,373,667 bp
  • T to A, chromosome 2 at 111,844,286 bp
  • T to C, chromosome 2 at 152,397,388 bp
  • T to A, chromosome 2 at 160,753,602 bp
  • T to C, chromosome 3 at 19,546,855 bp
  • T to G, chromosome 3 at 115,101,880 bp
  • T to C, chromosome 4 at 11,051,150 bp
  • G to T, chromosome 4 at 59,092,497 bp
  • T to C, chromosome 4 at 63,168,517 bp
  • T to C, chromosome 4 at 124,682,243 bp
  • T to G, chromosome 4 at 140,944,537 bp
  • C to T, chromosome 4 at 148,938,696 bp
  • T to A, chromosome 4 at 148,938,969 bp
  • T to C, chromosome 4 at 150,196,135 bp
  • T to C, chromosome 5 at 3,769,633 bp
  • G to T, chromosome 5 at 32,975,506 bp
  • A to T, chromosome 5 at 105,812,606 bp
  • T to A, chromosome 6 at 4,629,993 bp
  • A to G, chromosome 6 at 21,772,747 bp
  • T to C, chromosome 6 at 41,376,804 bp
  • T to A, chromosome 6 at 81,946,599 bp
  • A to T, chromosome 6 at 108,423,336 bp
  • G to A, chromosome 6 at 124,326,609 bp
  • A to G, chromosome 7 at 19,857,822 bp
  • A to G, chromosome 7 at 90,236,316 bp
  • A to C, chromosome 7 at 126,759,858 bp
  • T to A, chromosome 8 at 11,216,788 bp
  • T to C, chromosome 8 at 40,558,358 bp
  • A to G, chromosome 8 at 85,970,914 bp
  • A to G, chromosome 8 at 105,093,165 bp
  • T to C, chromosome 9 at 18,304,362 bp
  • T to C, chromosome 9 at 22,002,422 bp
  • T to C, chromosome 9 at 106,063,044 bp
  • T to C, chromosome 9 at 107,692,193 bp
  • G to T, chromosome 10 at 7,774,050 bp
  • A to T, chromosome 10 at 33,949,047 bp
  • T to A, chromosome 10 at 39,551,461 bp
  • A to T, chromosome 10 at 62,559,402 bp
  • T to A, chromosome 11 at 42,317,562 bp
  • A to T, chromosome 11 at 50,922,455 bp
  • G to T, chromosome 11 at 96,827,359 bp
  • C to T, chromosome 11 at 98,695,596 bp
  • G to C, chromosome 13 at 32,806,966 bp
  • A to T, chromosome 13 at 38,195,434 bp
  • T to C, chromosome 13 at 41,004,800 bp
  • C to T, chromosome 13 at 58,343,970 bp
  • C to T, chromosome 13 at 119,445,790 bp
  • T to A, chromosome 14 at 31,616,388 bp
  • C to T, chromosome 14 at 51,764,251 bp
  • T to C, chromosome 14 at 55,631,189 bp
  • G to A, chromosome 15 at 28,311,207 bp
  • G to T, chromosome 15 at 28,311,208 bp
  • T to A, chromosome 15 at 39,143,653 bp
  • G to T, chromosome 17 at 45,566,661 bp
  • A to T, chromosome 17 at 56,652,493 bp
  • A to T, chromosome 17 at 88,743,008 bp
  • G to A, chromosome 18 at 37,490,484 bp
  • C to T, chromosome 18 at 37,941,341 bp
  • G to A, chromosome 19 at 7,199,985 bp
  • T to G, chromosome 19 at 8,742,311 bp
  • T to C, chromosome 19 at 36,117,877 bp
  • T to C, chromosome 19 at 53,013,489 bp
  • C to A, chromosome X at 167,306,882 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5929 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044124-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.