Strain Name:
C57BL/6J-MtgxR6048Btlr/Mmmh
Stock Number:
044216-MU
Citation ID:
RRID:MMRRC_044216-MU
Other Names:
R6048 (G1)
Major Collection:

Strain Information

Sipa1l1
Name: signal-induced proliferation-associated 1 like 1
Synonyms: 4931426N11Rik, Spar
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217692
VEGA: 12
Homologene: 9189
Clcnka
Name: chloride channel, voltage-sensitive Ka
Synonyms: Clcnk1, CLC-K1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12733
Homologene: 65
Aopep
Name: aminopeptidase O
Synonyms: ApO, 2010111I01Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72061
HGNC: HGNC:1361
Homologene: 66273
Pdzd2
Name: PDZ domain containing 2
Synonyms: LOC223364, 4930537L06Rik, Pdzk3, A930022H17Rik, Gm21706
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 68070
Homologene: 23393
Kif1b
Name: kinesin family member 1B
Synonyms: Kif1b beta, A530096N05Rik, N-3 kinesin, D4Mil1e, KIF1Bp204, KIF1Bp130, Kif1b alpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16561
Homologene: 99835
Snx5
Name: sorting nexin 5
Synonyms: 0910001N05Rik, D2Ertd52e, 1810032P22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69178
Homologene: 40944
Tanc2
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Synonyms: 3526402J09Rik, 5730590C14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 77097
Homologene: 64680
Ruvbl1
Name: RuvB-like AAA ATPase 1
Synonyms: Pontin52, 2510009G06Rik, Tip49a
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56505
Homologene: 37839
Rnf216
Name: ring finger protein 216
Synonyms: F830018F18Rik, UIP83, Ubce7ip1, 2810055G22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 108086
Homologene: 19442
Dclk2
Name: doublecortin-like kinase 2
Synonyms: 6330415M09Rik, Click-II, Dcamkl2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70762
Homologene: 69431
Clmp
Name: CXADR-like membrane protein
Synonyms: 9030425E11Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71566
Homologene: 11705
Arl4c
Name: ADP-ribosylation factor-like 4C
Synonyms: A630084M22Rik, Arl7
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 320982
HGNC: HGNC:698
Homologene: 4193
Scyl2
Name: SCY1-like 2 (S. cerevisiae)
Synonyms: CVAK104, D10Ertd802e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 213326
Homologene: 13349
Gm6563
Name: predicted pseudogene 6563
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 625193
VEGA: 19
Il17re
Name: interleukin 17 receptor E
Synonyms: Il25r
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 57890
Homologene: 17109
Ms4a6b
Name: membrane-spanning 4-domains, subfamily A, member 6B
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 69774
Homologene: 128306
Nol8
Name: nucleolar protein 8
Synonyms: 4921532D18Rik, 5730412B09Rik, D13Ertd548e
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 70930
VEGA: 13
Homologene: 41210
Ints7
Name: integrator complex subunit 7
Synonyms: 5930412E23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 77065
Homologene: 9136
Usp37
Name: ubiquitin specific peptidase 37
Synonyms: C330008N13Rik, 4932415L06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319651
Homologene: 10858
Enpp1
Name: ectonucleotide pyrophosphatase/phosphodiesterase 1
Synonyms: Pca, Pca-1, E-NPP1, CD203c, NPP1, twy, 4833416E15Rik, PC-1, Ly-41, Npps, Pdnp1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18605
HGNC: HGNC:3356
Homologene: 38151
Dact2
Name: dishevelled-binding antagonist of beta-catenin 2
Synonyms: Dpr2, Frd2, 2900084M21Rik, dapper2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240025
VEGA: 17
Homologene: 18237
Fgd3
Name: FYVE, RhoGEF and PH domain containing 3
Synonyms: 5830461L01Rik, ZFYVE5
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 30938
Homologene: 22925
Spmip2
Name: sperm microtubule inner protein 2
Synonyms: Gm17359
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100233207
Homologene: 105634
Aldh1a2
Name: aldehyde dehydrogenase family 1, subfamily A2
Synonyms: Aldh1a7, retinaldehyde dehydrogenase, Raldh2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19378
Homologene: 68368
Nxph1
Name: neurexophilin 1
Synonyms: C130005L03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18231
Homologene: 8284
Tns2
Name: tensin 2
Synonyms: nep, nph, Tenc1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 209039
VEGA: 15
Homologene: 37077
Eral1
Name: Era like 12S mitochondrial rRNA chaperone 1
Synonyms: 9130407C09Rik, 2610524P08Rik, MERA-W, MERA-S
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 57837
HGNC: HGNC:3424
Homologene: 4167
Or1n1
Name: olfactory receptor family 1 subfamily N member 1
Synonyms: GA_x6K02T2NLDC-33554926-33553994, Olfr351, MOR127-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258944
HGNC: HGNC:8221
Homologene: 10583
Col5a3
Name: collagen, type V, alpha 3
Synonyms: Pro-alpha3(V)
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 53867
Homologene: 9253
Ralgapa2
Name: Ral GTPase activating protein, alpha subunit 2 (catalytic)
Synonyms: RGC2, A230067G21Rik, AS250
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241694
Homologene: 28131
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: mXin beta, myomaxin, 2310003D02Rik, Cmya3, 2310008C07Rik, A530024P18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241431
Homologene: 19388
Gm11639
Name: predicted gene 11639
Synonyms: Gm11639, Efcab15
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 105242472
Carmil3
Name: capping protein regulator and myosin 1 linker 3
Synonyms: Lrrc16b
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268747
VEGA: 14
Homologene: 74564
Prkce
Name: protein kinase C, epsilon
Synonyms: Pkce, PCK epsilon, 5830406C15Rik, PKC[e], PKCepsilon
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18754
HGNC: HGNC:9401
Homologene: 48343
Grm5
Name: glutamate receptor, metabotropic 5
Synonyms: Glu5R, mGluR5, Gprc1e, 6430542K11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108071
HGNC: HGNC:4597
Homologene: 37354
Frem3
Name: Fras1 related extracellular matrix protein 3
Synonyms: LOC333315
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 333315
Homologene: 35388
Vps37a
Name: vacuolar protein sorting 37A
Synonyms: 2210018P21Rik, 4930592A21Rik, D8Ertd531e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 52348
VEGA: 8
Homologene: 45120
Ddx60
Name: DExD/H box helicase 60
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234311
Homologene: 23031
Itih1
Name: inter-alpha trypsin inhibitor, heavy chain 1
Synonyms: Intin1, Itih-1, inter-alpha (globulin) inhibitor, H1 polypeptide
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16424
HGNC: HGNC:6166
Homologene: 1667
Or2bd2
Name: olfactory receptor family 2 subfamily BD member 2
Synonyms: MOR124-1, Olfr1344, 4930415J05Rik, GA_x6K02T2QGBW-3169916-3170881
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257882
Tmem132d
Name: transmembrane protein 132D
Synonyms: C630028F04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243274
Homologene: 71684
Papolg
Name: poly(A) polymerase gamma
Synonyms: 9630006B20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216578
Homologene: 56959
Ntn4
Name: netrin 4
Synonyms: beta-netrin
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 57764
Homologene: 10934
Gadl1
Name: glutamate decarboxylase-like 1
Synonyms: 1110027M19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73748
Homologene: 45812
Bst1
Name: bone marrow stromal cell antigen 1
Synonyms: CD157, Ly65, Bp3, Bsta1, 114/A10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12182
HGNC: HGNC:1118
Homologene: 3198
Pde3b
Name: phosphodiesterase 3B, cGMP-inhibited
Synonyms: 9830102A01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18576
HGNC: HGNC:8779
Homologene: 709
Sorcs2
Name: sortilin-related VPS10 domain containing receptor 2
Synonyms: VPS10 domain receptor protein
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 81840
Homologene: 56899
Or5ac20
Name: olfactory receptor family 5 subfamily AC member 20
Synonyms: GA_x54KRFPKG5P-55498766-55497843, Olfr202, MOR182-1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258997
Homologene: 138323
Epb42
Name: erythrocyte membrane protein band 4.2
Synonyms: Epb4.2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13828
HGNC: HGNC:3381
Homologene: 93
Zfp946
Name: zinc finger protein 946
Synonyms: 1300003B13Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74149
Or3a1
Name: olfactory receptor family 3 subfamily A member 1
Synonyms: GA_x6K02T2P1NL-4467421-4466474, Olfr410, MOR255-5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258702
Homologene: 68262
Gm10787
Name: predicted gene 10787
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100038479
VEGA: 10
Or51f1d
Name: olfactory receptor family 51 subfamily F member 1D
Synonyms: Olfr583, MOR14-6, GA_x6K02T2PBJ9-5762668-5763618
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258752
Homologene: 133721
Eif3i
Name: eukaryotic translation initiation factor 3, subunit I
Synonyms: D4Ertd632e, Eif3s2, TRIP-1, 36kDa
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 54709
HGNC: HGNC:3272
Homologene: 2786
Or6c219
Name: olfactory receptor family 6 subfamily C member 219
Synonyms: GA_x6K02T2PULF-11624146-11623190, Olfr818, MOR110-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258773
Homologene: 74100
Oxsm
Name: 3-oxoacyl-ACP synthase, mitochondrial
Synonyms: 4933425A18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 71147
Homologene: 5820
Vmn1r79
Name: vomeronasal 1 receptor 79
Synonyms: Gm9807
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100042437
Homologene: 128342
Cln6
Name: ceroid-lipofuscinosis, neuronal 6
Synonyms: 1810065L06Rik, D9Bwg1455e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76524
HGNC: HGNC:2077
Homologene: 9898
Sertad2
Name: SERTA domain containing 2
Synonyms: SEI-2, Sei2, Trip-Br2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 58172
Homologene: 8843
Mxd1
Name: MAX dimerization protein 1
Synonyms: Mad1, Mad
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17119
HGNC: HGNC:6761
Homologene: 1767
Fbxl16
Name: F-box and leucine-rich repeat protein 16
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 214931
VEGA: 17
Homologene: 17732
Cflar
Name: CASP8 and FADD-like apoptosis regulator
Synonyms: c-Flip, 2310024N18Rik, Casper, Flip, Cash, A430105C05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12633
HGNC: HGNC:1876
Homologene: 7652
H2ac11
Name: H2A clustered histone 11
Synonyms: Hist1h2ag
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319167
HGNC: HGNC:4734
Homologene: 135982
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 58,741,043 bp
  • A to T, chromosome 1 at 74,478,136 bp
  • A to G, chromosome 1 at 88,701,628 bp
  • A to G, chromosome 1 at 191,621,412 bp
  • A to G, chromosome 2 at 36,859,841 bp
  • T to A, chromosome 2 at 67,508,243 bp
  • T to A, chromosome 2 at 121,024,408 bp
  • T to C, chromosome 2 at 144,259,153 bp
  • T to C, chromosome 2 at 146,434,845 bp
  • T to C, chromosome 3 at 79,405,885 bp
  • G to T, chromosome 3 at 86,905,965 bp
  • T to C, chromosome 4 at 129,593,352 bp
  • T to A, chromosome 4 at 141,394,487 bp
  • A to G, chromosome 4 at 149,263,629 bp
  • G to T, chromosome 5 at 36,027,988 bp
  • G to T, chromosome 5 at 43,818,964 bp
  • A to G, chromosome 5 at 128,269,117 bp
  • A to G, chromosome 5 at 143,068,904 bp
  • A to T, chromosome 6 at 9,247,103 bp
  • C to A, chromosome 6 at 86,650,984 bp
  • C to T, chromosome 6 at 88,482,991 bp
  • T to C, chromosome 6 at 113,470,108 bp
  • A to C, chromosome 7 at 6,440,355 bp
  • T to C, chromosome 7 at 12,176,521 bp
  • T to C, chromosome 7 at 88,026,550 bp
  • A to G, chromosome 7 at 103,051,319 bp
  • T to A, chromosome 7 at 114,508,267 bp
  • C to T, chromosome 8 at 40,528,322 bp
  • T to C, chromosome 8 at 62,000,582 bp
  • T to C, chromosome 8 at 80,613,433 bp
  • C to T, chromosome 9 at 20,807,619 bp
  • T to A, chromosome 9 at 40,771,109 bp
  • T to C, chromosome 9 at 62,844,626 bp
  • T to C, chromosome 9 at 71,261,767 bp
  • A to G, chromosome 9 at 116,006,701 bp
  • T to C, chromosome 10 at 24,660,254 bp
  • C to T, chromosome 10 at 77,021,842 bp
  • A to T, chromosome 10 at 89,645,486 bp
  • T to A, chromosome 10 at 93,707,266 bp
  • A to G, chromosome 10 at 129,945,826 bp
  • A to G, chromosome 11 at 20,648,436 bp
  • A to C, chromosome 11 at 23,891,815 bp
  • A to T, chromosome 11 at 74,335,135 bp
  • G to A, chromosome 11 at 78,075,783 bp
  • A to G, chromosome 11 at 104,944,433 bp
  • G to A, chromosome 11 at 105,867,717 bp
  • A to T, chromosome 12 at 82,440,869 bp
  • A to G, chromosome 13 at 22,042,836 bp
  • G to A, chromosome 13 at 49,273,748 bp
  • T to A, chromosome 13 at 49,653,684 bp
  • T to A, chromosome 13 at 63,240,325 bp
  • T to A, chromosome 14 at 16,242,308 bp
  • A to G, chromosome 14 at 30,929,823 bp
  • G to A, chromosome 14 at 55,503,845 bp
  • A to T, chromosome 15 at 12,592,570 bp
  • G to A, chromosome 15 at 102,111,411 bp
  • C to T, chromosome 16 at 59,283,979 bp
  • A to G, chromosome 17 at 14,197,305 bp
  • G to A, chromosome 17 at 22,454,840 bp
  • A to G, chromosome 17 at 25,816,993 bp
  • C to A, chromosome 17 at 86,493,347 bp
  • T to C, chromosome 19 at 11,520,370 bp
  • A to G, chromosome 19 at 23,675,882 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6048 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044216-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.