• Introduction

• Review Criteria

• Application Stage

• Strain Acceptance

• Transfer Methods

• Submission Types

• Contract Submissions

Introduction to MMRRC Submission Process

Thank you for your interest in submitting your mouse strain to the Mutant Mouse Regional Resource Centers (MMRRC).

The MMRRC exists to serve the research community by preserving biomedically valuable mouse strains and mutagenated cell line collections, and distributing these strains to the research community for internal, non-commercial research purposes. The Donating Investigator (DI) or their institution retains ownership of the strain. The MMRRC acts with the DI's and their institution's authorization to distribute their strain.

To assure the broadest benefit to the biomedical research community, the MMRRC encourages that strains be submitted with minimal restrictions; the only donor-stipulated restriction the MMRRC accepts is to restrict redistribution to non-profit institutions. In order to minimize administrative delays, it is the responsibility of the Requesting Investigator to obtain appropriate licenses for any relevant patents if necessary.

The MMRRC members meet monthly to review new submission applications. Submissions undergo a thorough review of the application and cited references and are evaluated according to the MMRRC's Review Criteria for acceptance for preservation in the repository.

Pre-authorized submissions are assigned primarily to the most appropriate MMRRC facility.

After acceptance and assignment, the MMRRC Informatics Center needs to obtain an MTA from the donor's institution and the geneotyping protocol used in the donor's laboratory. Additionally, the assigned MMRRC facility needs a copy of the most recent Health Status Monitor Report. The assigned facility will work closely with you throughout the remainder of the transfer process. The donating institution is responsible for the cost of shipping their strain(s) to the assigned MMRRC facility.

If you’d like to submit your strain to the MMRRC, please fill out our submission form.