Strain Name:
C57BL/6J-MtgxR0385Btlr/Mmmh
Stock Number:
038591-MU
Citation ID:
RRID:MMRRC_038591-MU
Other Names:
R0385 (G1), C57BL/6J-MtgxR0385Btlr
Major Collection:

Strain Information

Dicer1
Name: dicer 1, ribonuclease type III
Synonyms: 1110006F08Rik, D12Ertd7e, Dicer1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 192119
VEGA: 12
Homologene: 13251
Slc1a3
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Synonyms: MGluT1, Eaat1, B430115D02Rik, GLAST, Gmt1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20512
Homologene: 20882
Atn1
Name: atrophin 1
Synonyms: atrophin-1, Atr1, Drpla
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13498
HGNC: HGNC:3033
Homologene: 1461
Tfdp2
Name: transcription factor Dp 2
Synonyms: DP3, DP-3, DP3, A330080J22Rik, 1110029I05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 211586
Homologene: 4578
Slit3
Name: slit guidance ligand 3
Synonyms: Slit1, b2b2362.1Clo
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20564
Homologene: 2303
Lpp
Name: LIM domain containing preferred translocation partner in lipoma
Synonyms: B130055L10Rik, 9430020K16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 210126
VEGA: 16
HGNC: HGNC:6679
Homologene: 4075
Adk
Name: adenosine kinase
Synonyms: AK, 5033405D03Rik, 2310026J05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11534
VEGA: 14
HGNC: HGNC:257
Homologene: 4891
Dusp1
Name: dual specificity phosphatase 1
Synonyms: mkp-1, erp, 3CH134, Ptpn16, MKP1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19252
HGNC: HGNC:3064
Homologene: 3254
Vps54
Name: VPS54 GARP complex subunit
Synonyms: Vps54l, 5330404P15Rik, mSLP8, wr
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245944
Homologene: 5605
Enpp2
Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
Synonyms: Autotaxin, Npps2, PD-Ialpha, Pdnp2, ATX
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18606
HGNC: HGNC:3357
Homologene: 4526
Frmd5
Name: FERM domain containing 5
Synonyms: 1500032A09Rik, A930004K21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228564
Homologene: 18206
Timeless
Name: timeless circadian clock 1
Synonyms: tim
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 21853
Homologene: 31206
Sec24d
Name: SEC24 homolog D, COPII coat complex component
Synonyms: 2310020L09Rik, LOC383951
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69608
Homologene: 40986
Slc25a25
Name: solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
Synonyms: 1110030N17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227731
Homologene: 62165
Rnf121
Name: ring finger protein 121
Synonyms: 4930544L10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75212
Homologene: 10132
Nasp
Name: nuclear autoantigenic sperm protein (histone-binding)
Synonyms: Epcs32, 5033430J04Rik, D4Ertd767e, Nasp-T
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 50927
HGNC: HGNC:7644
Homologene: 133894
Fam222b
Name: family with sequence similarity 222, member B
Synonyms: BC017647
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216971
Homologene: 10054
Mbd1
Name: methyl-CpG binding domain protein 1
Synonyms: PCM1, Cxxc3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17190
VEGA: 18
HGNC: HGNC:6916
Homologene: 8414
Dkk3
Name: dickkopf WNT signaling pathway inhibitor 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 50781
HGNC: HGNC:2893
Homologene: 8303
Gal
Name: galanin and GMAP prepropeptide
Synonyms: Galn
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14419
VEGA: 19
HGNC: HGNC:4114
Homologene: 7724
Mcm10
Name: minichromosome maintenance 10 replication initiation factor
Synonyms: C330019M07Rik, 2410041F14Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70024
Homologene: 41275
Supt16
Name: SPT16, facilitates chromatin remodeling subunit
Synonyms: Cdc68, Fact140, Spt16, Supt16h
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 114741
VEGA: 14
Homologene: 5207
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: 4930400K19Rik, Tulip1, 2310003F20Rik, Garnl1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56784
VEGA: 12
Homologene: 84805
Camta1
Name: calmodulin binding transcription activator 1
Synonyms: 2310058O09Rik, 1810059M14Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100072
Homologene: 18942
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, Acc1, LOC327983, Acac, A530025K05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
C2cd5
Name: C2 calcium-dependent domain containing 5
Synonyms: C030008B15Rik, CDP138, 5730419I09Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74741
Homologene: 8873
Sf3b4
Name: splicing factor 3b, subunit 4
Synonyms: SF3b49, Sap49, 49kDa
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 107701
Homologene: 134086
Entr1
Name: endosome associated trafficking regulator 1
Synonyms: C630038K21Rik, C330016H24Rik, Sdccag3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68112
Homologene: 74578
Apc
Name: APC, WNT signaling pathway regulator
Synonyms: Min, CC1, adenomatosis polyposis coli
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 11789
HGNC: HGNC:583
Homologene: 30950
Slc20a2
Name: solute carrier family 20, member 2
Synonyms: MolPit2, PiT-2, Ram-1, Ram1, Pit-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20516
Homologene: 68531
Sorl1
Name: sortilin-related receptor, LDLR class A repeats-containing
Synonyms: LR11, mSorLA, 2900010L19Rik, Sorla
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20660
Homologene: 2336
Oser1
Name: oxidative stress responsive serine rich 1
Synonyms: 3230401D17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66680
Homologene: 9521
Arhgap28
Name: Rho GTPase activating protein 28
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268970
Homologene: 18264
Taf4b
Name: TATA-box binding protein associated factor 4b
Synonyms: Taf2c2, TAFII105, 105kDa, 2610524B04Rik, 4932409F03Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 72504
VEGA: 18
Homologene: 28266
Tpcn2
Name: two pore segment channel 2
Synonyms: D830047E22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233979
Homologene: 16375
Rbm45
Name: RNA binding motif protein 45
Synonyms: Drb1, G430095G15Rik, Drbp1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241490
Homologene: 15560
Tapt1
Name: transmembrane anterior posterior transformation 1
Synonyms: 4932414K18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231225
Homologene: 80206
Tmco3
Name: transmembrane and coiled-coil domains 3
Synonyms: B230339H12Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234076
Homologene: 32376
Klk4
Name: kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)
Synonyms: KLK-L1, ESMP1, Prss17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56640
HGNC: HGNC:6365
Homologene: 55856
Idh2
Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Synonyms: Idh-2, IDPm
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269951
HGNC: HGNC:5383
Homologene: 37590
Fastkd2
Name: FAST kinase domains 2
Synonyms: 2810421I24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75619
Homologene: 8957
Usp2
Name: ubiquitin specific peptidase 2
Synonyms: ubp41, B930035K21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 53376
Homologene: 3098
Ttn
Name: titin
Synonyms: connectin, L56, 1100001C23Rik, mdm, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Pcdhb4
Name: protocadherin beta 4
Synonyms: Pcdhb5A, PcdhbD
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93875
HGNC: HGNC:8690
Homologene: 62176
Ptprd
Name: protein tyrosine phosphatase receptor type D
Synonyms: 3000002J10Rik, B230219D21Rik, 1110002J03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19266
HGNC: HGNC:9668
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Cdk5rap3
Name: CDK5 regulatory subunit associated protein 3
Synonyms: 1810007E24Rik, OK/SW-cl.114, MST016, HSF-27, IC53, C53
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 80280
Homologene: 12718
Wnk2
Name: WNK lysine deficient protein kinase 2
Synonyms: ESTM15, 1810073P09Rik, X83337
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75607
Homologene: 19155
Pnpla5
Name: patatin-like phospholipase domain containing 5
Synonyms: GS2L, 4833426H19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75772
VEGA: 15
Homologene: 13376
Kdm1b
Name: lysine (K)-specific demethylase 1B
Synonyms: 4632428N09Rik, Aof1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218214
Homologene: 14695
Slfn10-ps
Name: schlafen 10, pseudogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237887
Npsr1
Name: neuropeptide S receptor 1
Synonyms: PGR14, VRR1, 9330128H10Rik, Gpr154
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319239
Homologene: 45515
Cap2
Name: cyclase associated actin cytoskeleton regulatory protein 2
Synonyms: 2810452G09Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67252
Homologene: 101397
Megf8
Name: multiple EGF-like-domains 8
Synonyms: Egfl4, b2b288Clo, b2b1702Clo, m687Ddg
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269878
HGNC: HGNC:3233
Homologene: 15988
Shank1
Name: SH3 and multiple ankyrin repeat domains 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243961
Homologene: 22949
Nup210
Name: nucleoporin 210
Synonyms: gp210, gp190, Pom210
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54563
Homologene: 41286
Gnptab
Name: N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
Synonyms: EG432486
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 432486
Homologene: 32576
Rad21
Name: RAD21 cohesin complex component
Synonyms: SCC1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19357
VEGA: 15
HGNC: HGNC:9811
Homologene: 38161
Plekhh3
Name: pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217198
Homologene: 11787
Dsg1c
Name: desmoglein 1 gamma
Synonyms: Dsg6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 211924
HGNC: HGNC:3048
Dpy19l3
Name: dpy-19 like C-mannosyltransferase 3
Synonyms: 9330164H19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233115
Homologene: 18692
Lilrb4b
Name: leukocyte immunoglobulin-like receptor, subfamily B, member 4B
Synonyms: gp49, Gp49a, Lilr4b
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14727
HGNC: HGNC:6608
Homologene: 86756
Klhdc7a
Name: kelch domain containing 7A
Synonyms: B230308G19Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242721
Homologene: 17567
Pcyt1a
Name: phosphate cytidylyltransferase 1, choline, alpha isoform
Synonyms: CTalpha, CTP:phosphocholine cytidylyltransferase alpha, Ctpct, Cttalpha, Cctalpha
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13026
HGNC: HGNC:8754
Homologene: 3680
Cdc42ep2
Name: CDC42 effector protein 2
Synonyms: Borg1, Cep2, 1110008C05Rik, D19Bwg1013e
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 104252
VEGA: 19
Homologene: 4933
Cntn5
Name: contactin 5
Synonyms: LOC244683, NB-2, A830025P08Rik, 6720426O10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244682
HGNC: HGNC:2175
Homologene: 28447
Fdps
Name: farnesyl diphosphate synthetase
Synonyms: Fdpsl1, 6030492I17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 110196
HGNC: HGNC:3631
Homologene: 1519
Krt82
Name: keratin 82
Synonyms: Krt2-20
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 114566
VEGA: 15
HGNC: HGNC:6459
Homologene: 13200
Usb1
Name: U6 snRNA biogenesis 1
Synonyms: AA960436
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 101985
Homologene: 11611
Fmo1
Name: flavin containing monooxygenase 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14261
HGNC: HGNC:3769
Homologene: 55520
Vmn1r13
Name: vomeronasal 1 receptor 13
Synonyms: V1rc5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113862
Homologene: 74368
Ptprb
Name: protein tyrosine phosphatase receptor type B
Synonyms: 3230402H02Rik, VE-PTP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19263
VEGA: 10
HGNC: HGNC:9665
Homologene: 2125
Mpv17l
Name: Mpv17 transgene, kidney disease mutant-like
Synonyms: M-LP
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 93734
Homologene: 13547
AC150897.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Pou2f2
Name: POU domain, class 2, transcription factor 2
Synonyms: Oct2b, Oct2a, Oct-2, Otf-2, Otf2, Oct2d, Oct2c
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18987
HGNC: HGNC:9213
Homologene: 55674
Rbbp8nl
Name: RBBP8 N-terminal like
Synonyms: BC066135
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 271887
Homologene: 76811
Zbed6
Name: zinc finger, BED type containing 6
Synonyms: similar to Zinc finger BED domain containing protein 4, Gm8466, MGR, Gm38394
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 667118
Homologene: 130066
Nol3
Name: nucleolar protein 3 (apoptosis repressor with CARD domain)
Synonyms: Nop30, B430311C09Rik, ARC
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 78688
HGNC: HGNC:7869
Homologene: 31208
Myb
Name: myeloblastosis oncogene
Synonyms: c-myb
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17863
HGNC: HGNC:7545
Homologene: 31311
Itgb5
Name: integrin beta 5
Synonyms: [b]5B, [b]5A, [b]-5, beta-5, beta5, [b]5, ESTM23
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 16419
HGNC: HGNC:6160
Homologene: 20511
Rhag
Name: Rhesus blood group-associated A glycoprotein
Synonyms: Rh50A, Rh50, CD241
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19743
Homologene: 68045
Gm5501
Name: predicted gene 5501
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 433161
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 63,737,811 bp
  • A to T, chromosome 1 at 133,656,784 bp
  • A to T, chromosome 1 at 162,836,204 bp
  • T to C, chromosome 2 at 5,004,154 bp
  • T to C, chromosome 2 at 26,387,659 bp
  • T to A, chromosome 2 at 32,417,822 bp
  • T to C, chromosome 2 at 76,376,519 bp
  • C to T, chromosome 2 at 76,881,717 bp
  • A to G, chromosome 2 at 121,555,574 bp
  • C to T, chromosome 2 at 163,411,396 bp
  • T to A, chromosome 2 at 180,281,273 bp
  • G to A, chromosome 3 at 89,094,894 bp
  • T to C, chromosome 3 at 96,172,982 bp
  • G to A, chromosome 3 at 123,353,733 bp
  • A to G, chromosome 4 at 76,128,665 bp
  • A to T, chromosome 4 at 116,610,695 bp
  • A to T, chromosome 4 at 139,966,705 bp
  • C to A, chromosome 4 at 151,075,140 bp
  • T to C, chromosome 5 at 44,218,101 bp
  • G to A, chromosome 6 at 57,210,705 bp
  • A to G, chromosome 6 at 91,028,795 bp
  • G to T, chromosome 6 at 124,743,371 bp
  • T to C, chromosome 6 at 143,041,490 bp
  • G to A, chromosome 7 at 25,116,076 bp
  • T to C, chromosome 7 at 25,355,961 bp
  • G to A, chromosome 7 at 35,752,705 bp
  • T to C, chromosome 7 at 43,884,008 bp
  • G to T, chromosome 7 at 44,344,291 bp
  • A to G, chromosome 7 at 45,259,056 bp
  • C to T, chromosome 7 at 80,098,257 bp
  • A to T, chromosome 7 at 102,029,117 bp
  • A to C, chromosome 7 at 112,158,223 bp
  • G to A, chromosome 7 at 141,638,400 bp
  • A to G, chromosome 7 at 145,277,174 bp
  • T to G, chromosome 8 at 13,296,027 bp
  • A to G, chromosome 8 at 22,568,393 bp
  • G to T, chromosome 8 at 95,345,318 bp
  • A to T, chromosome 8 at 105,279,887 bp
  • C to T, chromosome 9 at 9,972,870 bp
  • A to G, chromosome 9 at 24,313,277 bp
  • C to A, chromosome 9 at 42,031,909 bp
  • C to G, chromosome 9 at 44,092,750 bp
  • T to A, chromosome 9 at 96,310,514 bp
  • T to C, chromosome 10 at 21,154,712 bp
  • T to A, chromosome 10 at 51,485,699 bp
  • T to C, chromosome 10 at 88,436,525 bp
  • A to G, chromosome 10 at 116,350,178 bp
  • C to T, chromosome 10 at 128,244,429 bp
  • A to G, chromosome 11 at 21,306,381 bp
  • A to G, chromosome 11 at 35,700,282 bp
  • C to A, chromosome 11 at 78,154,930 bp
  • T to C, chromosome 11 at 83,029,117 bp
  • A to G, chromosome 11 at 84,231,748 bp
  • A to G, chromosome 11 at 96,916,209 bp
  • T to C, chromosome 11 at 101,165,141 bp
  • A to G, chromosome 12 at 55,677,038 bp
  • A to T, chromosome 12 at 104,704,174 bp
  • T to C, chromosome 13 at 46,560,547 bp
  • T to G, chromosome 13 at 47,064,240 bp
  • G to T, chromosome 13 at 49,068,128 bp
  • A to G, chromosome 14 at 21,318,074 bp
  • A to C, chromosome 14 at 52,176,718 bp
  • C to T, chromosome 15 at 8,639,135 bp
  • A to T, chromosome 15 at 51,973,863 bp
  • C to T, chromosome 15 at 54,882,159 bp
  • G to T, chromosome 15 at 84,120,719 bp
  • C to T, chromosome 15 at 101,545,593 bp
  • A to T, chromosome 16 at 13,940,999 bp
  • T to C, chromosome 16 at 24,761,837 bp
  • T to C, chromosome 16 at 32,466,433 bp
  • T to A, chromosome 16 at 33,944,094 bp
  • A to T, chromosome 17 at 26,507,696 bp
  • T to A, chromosome 17 at 40,834,727 bp
  • T to C, chromosome 17 at 67,864,606 bp
  • C to T, chromosome 18 at 9,917,042 bp
  • T to C, chromosome 18 at 14,783,760 bp
  • C to T, chromosome 18 at 20,283,654 bp
  • T to A, chromosome 18 at 34,315,944 bp
  • T to C, chromosome 18 at 37,309,215 bp
  • AGCTGACTCGGTAC to A, chromosome 18 at 74,273,241 bp
  • C to T, chromosome 19 at 3,411,171 bp
  • T to A, chromosome 19 at 5,918,525 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0385 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038591-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.