Strain Name:
C57BL/6J-MtgxR9722Btlr/Mmmh
Stock Number:
069969-MU
Citation ID:
RRID:MMRRC_069969-MU
Other Names:
R9722 (G1)
Major Collection:

Strain Information

Myo10
Name: myosin X
Synonyms: myosin-X, D15Ertd600e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17909
HGNC: HGNC:7593
Homologene: 36328
Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Pofut2
Name: protein O-fucosyltransferase 2
Synonyms: FUT13, 2310011G23Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 80294
VEGA: 10
Homologene: 12724
Sgsm1
Name: small G protein signaling modulator 1
Synonyms: 2410098H20Rik, D5Bwg1524e, Rutbc2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52850
Homologene: 64485
Map3k4
Name: mitogen-activated protein kinase kinase kinase 4
Synonyms: MTK1, MAPKKK4, D17Rp17, RP17, D17Rp17e, Mekk4, T-associated sex reversal, Tas
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 26407
VEGA: 17
HGNC: HGNC:6856
Homologene: 31346
Zfp638
Name: zinc finger protein 638
Synonyms: Np220, Zfml
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18139
Homologene: 7447
Odf2
Name: outer dense fiber of sperm tails 2
Synonyms: MMTEST29, cenexin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18286
HGNC: HGNC:8114
Homologene: 1907
Tpx2
Name: TPX2, microtubule-associated
Synonyms: REPP86, DIL2, p100, 2610005B21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72119
HGNC: HGNC:1249
Homologene: 8107
Nckap1
Name: NCK-associated protein 1
Synonyms: mh19, Hem-2, H19, Nap1, Hem2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 50884
HGNC: HGNC:7666
Homologene: 8384
Zfp985
Name: zinc finger protein 985
Synonyms: Gm13154
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433804
Homologene: 133076
Esr1
Name: estrogen receptor 1 (alpha)
Synonyms: ESR, ERalpha, ER[a], Nr3a1, ERa, Estr, Estra, ER-alpha
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13982
HGNC: HGNC:3467
Homologene: 47906
Cyfip2
Name: cytoplasmic FMR1 interacting protein 2
Synonyms: Pir121, 6430511D02Rik, 1500004I01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76884
Homologene: 7936
Eif2d
Name: eukaryotic translation initiation factor 2D
Synonyms: D1Ertd5e, Lgtn
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16865
HGNC: HGNC:6583
Homologene: 38244
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Slc39a4
Name: solute carrier family 39 (zinc transporter), member 4
Synonyms: zip4, 1600025H15Rik, AWMS2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72027
VEGA: 15
Homologene: 15638
Nog
Name: noggin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18121
HGNC: HGNC:7866
Homologene: 3979
Ppfia1
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Synonyms: liprin, C030014K08Rik, Liprin-alpha1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233977
HGNC: HGNC:9245
Homologene: 20802
Canx
Name: calnexin
Synonyms: 1110069N15Rik, CNX
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12330
HGNC: HGNC:1473
Homologene: 1324
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Gtl5, Wcrf180, Acf1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Mpdz
Name: multiple PDZ domain crumbs cell polarity complex component
Synonyms: MUPP1, B930003D11Rik, multiple PDZ domain protein
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17475
HGNC: HGNC:7208
Homologene: 2841
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, 2610100B16Rik, Odz3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23965
Homologene: 22673
Ube2v2
Name: ubiquitin-conjugating enzyme E2 variant 2
Synonyms: MMS2, 5730524P06Rik, 4632410D19Rik, 1110021H13Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70620
Homologene: 55739
Snx11
Name: sorting nexin 11
Synonyms: 4933439F10Rik, A930041K09Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74479
Homologene: 12568
Trim33
Name: tripartite motif-containing 33
Synonyms: Tif1g, 8030451N04Rik, ectodermin, Ecto
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 94093
Homologene: 9296
Gemin5
Name: gem nuclear organelle associated protein 5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216766
Homologene: 9155
Zfp599
Name: zinc finger protein 599
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235048
Homologene: 138456
Piezo1
Name: piezo-type mechanosensitive ion channel component 1
Synonyms: Piezo1, Fam38a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234839
Homologene: 124356
Tnip2
Name: TNFAIP3 interacting protein 2
Synonyms: ABIN-2, 1810020H16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231130
Homologene: 11515
Tek
Name: TEK receptor tyrosine kinase
Synonyms: Hyk, Tie2, Cd202b, tie-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21687
Homologene: 397
Ccnt2
Name: cyclin T2
Synonyms: 2900041I18Rik, CycT2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72949
HGNC: HGNC:1600
Homologene: 14043
Pigg
Name: phosphatidylinositol glycan anchor biosynthesis, class G
Synonyms: Gpi7
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 433931
Homologene: 39421
Ephb2
Name: Eph receptor B2
Synonyms: eteck, Erk, Tyro5, Prkm5, Nuk, Drt, Hek5, Sek3, Qek5, Cek5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13844
HGNC: HGNC:3393
Homologene: 37925
Pcnx4
Name: pecanex homolog 4
Synonyms: 1810048J11Rik, Pcnxl4
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 67708
VEGA: 12
Homologene: 23366
Antxr2
Name: anthrax toxin receptor 2
Synonyms: cI-35, CMG-2, CMG2, 2310046B19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71914
Homologene: 43236
Astn2
Name: astrotactin 2
Synonyms: 1d8, Astnl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56079
Homologene: 77850
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22635
Homologene: 124417
Pglyrp3
Name: peptidoglycan recognition protein 3
Synonyms: LOC242100
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242100
Homologene: 71559
Pcdhga11
Name: protocadherin gamma subfamily A, 11
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93723
HGNC: HGNC:8698
Homologene: 110934
Fbxo2
Name: F-box protein 2
Synonyms: NFB42, FBX2, Fbs1, Prpl4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230904
Homologene: 8132
Vmn1r22
Name: vomeronasal 1 receptor 22
Synonyms: V1rc23
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171196
Homologene: 110825
Tas2r126
Name: taste receptor, type 2, member 126
Synonyms: Tas2r26, mGR26, T2R12, mt2r35, T2R26
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387353
Homologene: 16412
Obox6
Name: oocyte specific homeobox 6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 252830
Vmn2r7
Name: vomeronasal 2, receptor 7
Synonyms: 4933425M15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 319217
Homologene: 129754
Abcc3
Name: ATP-binding cassette, sub-family C member 3
Synonyms: 1700019L09Rik, MRP3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76408
HGNC: HGNC:54
Homologene: 68364
Foxred1
Name: FAD-dependent oxidoreductase domain containing 1
Synonyms: TEG-23, Tex23
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235169
Homologene: 9712
Srm
Name: spermidine synthase
Synonyms: SpdSy, SpdST
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20810
Homologene: 40514
9330159F19Rik
Name: RIKEN cDNA 9330159F19 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 212448
VEGA: 10
Homologene: 8804
Pfpl
Name: pore forming protein-like
Synonyms: Epcs5, Epcs50
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56093
VEGA: 19
Homologene: 130704
Slc5a7
Name: solute carrier family 5 (choline transporter), member 7
Synonyms: CHT1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 63993
VEGA: 17
Homologene: 32516
Sdr16c5
Name: short chain dehydrogenase/reductase family 16C, member 5
Synonyms: Scdr9, Rdhe2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242285
Homologene: 15039
Map3k3
Name: mitogen-activated protein kinase kinase kinase 3
Synonyms: MAPKKK3, Mekk3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 26406
HGNC: HGNC:6855
Homologene: 69110
Dnajc9
Name: DnaJ heat shock protein family (Hsp40) member C9
Synonyms: 5330419I01Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 108671
VEGA: 14
Homologene: 9055
Cd209c
Name: CD209c antigen
Synonyms: SIGNR2, mSIGNR2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 170776
HGNC: HGNC:1641
Homologene: 87186
Phactr3
Name: phosphatase and actin regulator 3
Synonyms: scapinin, 1500003N10Rik, 4930415A02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74189
Homologene: 14482
Tspan13
Name: tetraspanin 13
Synonyms: 1100001I23Rik, Tm4sf13
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 66109
Homologene: 8671
Or6c74
Name: olfactory receptor family 6 subfamily C member 74
Synonyms: GA_x6K02T2PULF-11704843-11705775, MOR109-1, Olfr821
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258772
Homologene: 27260
Krtap4-13
Name: keratin associated protein 4-13
Synonyms: 2300006N05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69464
Homologene: 124486
Igkv4-57-1
Name: immunoglobulin kappa variable 4-57-1
Synonyms: LOC384514
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 384514
Dchs2
Name: dachsous cadherin related 2
Synonyms: LOC229459
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100534287
Gm17655
Name: predicted gene, 17655
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100504130
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 127,802,188 bp (GRCm38)
  • T to C, chromosome 1 at 131,165,211 bp (GRCm38)
  • A to G, chromosome 2 at 29,923,582 bp (GRCm38)
  • G to A, chromosome 2 at 80,571,224 bp (GRCm38)
  • C to A, chromosome 2 at 130,961,616 bp (GRCm38)
  • T to A, chromosome 2 at 152,891,556 bp (GRCm38)
  • G to A, chromosome 2 at 178,256,250 bp (GRCm38)
  • G to A, chromosome 3 at 64,690,986 bp (GRCm38)
  • A to G, chromosome 3 at 83,353,994 bp (GRCm38)
  • A to G, chromosome 3 at 92,031,388 bp (GRCm38)
  • C to A, chromosome 3 at 103,353,830 bp (GRCm38)
  • A to T, chromosome 4 at 4,005,595 bp (GRCm38)
  • C to T, chromosome 4 at 65,913,741 bp (GRCm38)
  • T to C, chromosome 4 at 81,386,267 bp (GRCm38)
  • T to G, chromosome 4 at 94,804,302 bp (GRCm38)
  • T to C, chromosome 4 at 136,657,457 bp (GRCm38)
  • A to C, chromosome 4 at 147,583,161 bp (GRCm38)
  • G to A, chromosome 4 at 148,164,426 bp (GRCm38)
  • T to A, chromosome 4 at 148,591,788 bp (GRCm38)
  • A to G, chromosome 5 at 34,496,868 bp (GRCm38)
  • T to C, chromosome 5 at 97,948,327 bp (GRCm38)
  • A to T, chromosome 5 at 108,347,901 bp (GRCm38)
  • A to G, chromosome 5 at 110,046,360 bp (GRCm38)
  • T to A, chromosome 5 at 113,280,341 bp (GRCm38)
  • T to C, chromosome 5 at 137,389,062 bp (GRCm38)
  • T to C, chromosome 6 at 42,435,148 bp (GRCm38)
  • A to T, chromosome 6 at 57,900,646 bp (GRCm38)
  • A to T, chromosome 6 at 69,544,509 bp (GRCm38)
  • T to A, chromosome 6 at 83,946,319 bp (GRCm38)
  • G to A, chromosome 7 at 15,834,906 bp (GRCm38)
  • A to G, chromosome 7 at 144,517,665 bp (GRCm38)
  • G to T, chromosome 8 at 3,945,905 bp (GRCm38)
  • A to T, chromosome 8 at 48,300,814 bp (GRCm38)
  • A to C, chromosome 8 at 122,498,758 bp (GRCm38)
  • T to A, chromosome 9 at 22,249,445 bp (GRCm38)
  • C to T, chromosome 9 at 35,206,004 bp (GRCm38)
  • G to A, chromosome 9 at 54,416,608 bp (GRCm38)
  • A to G, chromosome 10 at 5,001,215 bp (GRCm38)
  • A to T, chromosome 10 at 29,218,273 bp (GRCm38)
  • T to C, chromosome 10 at 77,266,925 bp (GRCm38)
  • A to G, chromosome 10 at 130,033,631 bp (GRCm38)
  • T to C, chromosome 11 at 46,196,308 bp (GRCm38)
  • A to G, chromosome 11 at 50,304,474 bp (GRCm38)
  • T to C, chromosome 11 at 58,150,592 bp (GRCm38)
  • A to G, chromosome 11 at 89,301,570 bp (GRCm38)
  • A to T, chromosome 11 at 94,359,246 bp (GRCm38)
  • A to G, chromosome 11 at 96,771,099 bp (GRCm38)
  • A to G, chromosome 11 at 99,809,354 bp (GRCm38)
  • A to G, chromosome 11 at 106,142,535 bp (GRCm38)
  • T to A, chromosome 12 at 36,024,018 bp (GRCm38)
  • C to T, chromosome 12 at 54,900,097 bp (GRCm38)
  • T to C, chromosome 12 at 72,556,265 bp (GRCm38)
  • T to C, chromosome 14 at 20,388,211 bp (GRCm38)
  • T to A, chromosome 15 at 25,801,141 bp (GRCm38)
  • A to G, chromosome 15 at 76,616,011 bp (GRCm38)
  • T to C, chromosome 16 at 15,577,035 bp (GRCm38)
  • A to C, chromosome 17 at 12,271,636 bp (GRCm38)
  • A to G, chromosome 17 at 54,296,957 bp (GRCm38)
  • T to C, chromosome 18 at 37,757,345 bp (GRCm38)
  • G to C, chromosome 19 at 12,428,933 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9722 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069969-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.