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About MMRRC

Introduction Background Publications Services Contact Information Other Resources FAQ
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MMRRC Center Services

Denotes service provided by center

Colony Management & Breeding
Service JAX MU UCD UNC
Colony management ✓ ✓ ✓
Backcrossing / Congenics ✓ ✓ ✓
Timed matings / embryo collections ✓ ✓ ✓
Gnotobiotics ✓
Assisted Reproductive Services
Service JAX MU UCD UNC
IVF / ICSI ✓ ✓ ✓ ✓
Cryopreservation / Cryorecovery ✓ ✓ ✓ ✓
Rederivation ✓ ✓ ✓ ✓
Rapid Colony Expansion ✓ ✓ ✓
ES Cell & Microinjection
Service JAX MU UCD UNC
Electroporation & selection in ES cells ✓ ✓
Genome editing (e.g., CRISPR/Cas9) ✓ ✓ ✓
Transgenics (e.g., plasmid, BAC) ✓ ✓ ✓
Genetic Analysis
Service JAX MU UCD UNC
PCR, qPCR, LRPCR, RT-PCR ✓ ✓ ✓
SNP analysis ✓ ✓ ✓ ✓
Loss of allele ✓ ✓
Transcriptome analysis ✓ ✓
QTL mapping ✓ ✓
Phenotyping
Service JAX MU UCD UNC
Behavioral testing ✓ ✓ ✓
Metabolics ✓ ✓
Imaging ✓ ✓
Auditory Brainstem Response (ABR) ✓
Eye exam ✓
Patient-Derived Xenograft (PDX) ✓ ✓ ✓ ✓
Microbiota characterization ✓
Pathology & Diagnostics
Service JAX MU UCD UNC
Pathogens: viral & bacterial ✓ ✓ ✓
Gross necropsy ✓ ✓ ✓ ✓
Histopathology ✓ ✓ ✓ ✓
Tissue collection ✓ ✓ ✓ ✓

MMRRC Functions and Services

Core Functions
  • Maintain, archive, and distribute biomedically valuable mouse strains, ES cell lines, and hybridomas.
  • Respond to requests from researchers for distribution of mice, ES cell lines, and hybridomas.
  • Conduct resource-related research to further enhance MMRRC operations and services relevant to mutant mice used in biomedical research.
Center Services
  • Perform microbiologic and genetic quality control of mice bred, maintained and distributed.
  • Provide contract services for resource preservation and distribution.
  • Offer additional related services as specifically provided by individual facilities (please use the table above to view these center-specific services).