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Contract Submissions

To better serve the research community, the MMRRC accepts strains on a fee-for-service basis through the following mechanisms:

  • NIH institute pre-authorized submissions
  • Sponsored submissions (of collections or sets)
  • Fee-for-service submissions (by individual donating investigators)

For NIH pre-authorized submissions, an institute Program Officer collaborates with the MMRRC's DPCPSI program officer to arrange a number of submission slots sponsored by the NIH institute. After DPCPSI approval, the sponsoring NIH institute selects the strains and informs the Donating Investigators to proceed with their applications as NIH-preauthorized submissions.

Other agencies, institutions, or consortia can also arrange for the submission of multiple lines. The funding entity coordinates with the DPCPSI program officer or directly with an MMRRC facility to contract a number of slots. While these contracts are reviewed by the MMRRC's Coordinating Committee, the funding entity proposes the mouse lines for deposition. Sponsored submissions are not individually evaluated at the MMRRC's Strain Reviews and are not required to meet the same scientific standards as unfunded submissions, which are preserved using DPCPSI's MMRRC grant funding.

Additionally, individual researchers with grant funding allocated for sharing mouse resources can arrange to deposit their mouse line with the MMRRC. Donors may either indicate the available funding on their submission application or work directly with an MMRRC facility to arrange a fee-for-service deposition.

Fees for archiving a mouse line for distribution to the research community are based on the specific services requested and the estimated costs of importing, preserving, and maintaining the strain. Each MMRRC facility offers various specialties and services; details can be found on the Functions and Services page. The cost to deposit a strain with the MMRRC ranges from $2,000 to $8,000, covering importation, cryopreservation, and genotype confirmation. Donors are responsible for shipping costs. The MMRRC advises donors to budget for the higher amount in their grant applications. Lower costs may apply if sperm cryopreservation is feasible, but higher costs might arise with lines that have poor breeding characteristics or require complex genotyping. Once ready to cryopreserve their model, Donating Investigators should contact Customer Service to request a contract submission. They will then be contacted by the MMRRC facilities with specific fee and service information and can choose which facility to work with.

The MMRRC is not liable for any expenses incurred should the strain become unavailable due to ownership or distribution rights by third parties or due to any subsequent decision by the Donating Investigator or their institution.