The MMRRC is pleased to welcome its newest collection of cell lines to the repository. The UC Davis/NIH NeuroMab Facility has deposited 473 Hybridoma Cell Lines into the MMRRC at UC Davis.

Hybridoma cell lines are immortal monoclonal antibody producing cells that can be grown in tissue culture at any scale to produce monoclonal antibodies. Each of the 473 cell lines in the MMRRC produced monoclonal antibodies validated for the specificity and efficacy in brain research applications at UC Davis/NIH NeuroMab Facility.

This new collection will empower researchers with the ability to produce large quantities of specific and highly validated monoclonal antibodies at low cost. One of the other benefits of having this collection in the MMRRC is that scientists also have access to knockout mouse lines for genes that encode protein targets of the NeuroMAb monoclonal antibodies. Accessibility of these cell lines will allow investigators to explore the dynamic organization of specific cell antibodies critical to understanding and improving health and disease.

Check out the new collection here

This October during Breast Cancer Awareness Month, the NIH is joining efforts across the U.S. to raise awareness, share information, and highlight research to help fight the disease. For more information on Breast Cancer, visit the NIH’s official website:

https://www.cancer.gov/

Popular MMRRC Breast Cancer Awareness Month Strains:

Contact us if you need assistance with learning more about strains related to Breast Cancer in the MMRRC repository.


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Welcome to the Mutant Mouse Resource & Research Centers (MMRRC) Website

The MMRRC is the nation’s premier national public repository system for mutant mice. Funded by the NIH continuously since 1999, the MMRRC archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by the biomedical research community. The MMRRC consists of a national network of breeding and distribution repositories and an Informatics Coordination and Service Center located at 4 major academic centers across the nation. The MMRRC is committed to upholding the highest standards of experimental design and quality control to optimize the reproducibility of research studies using mutant mice. The MMRRC is supported by the Office of Research Infrastructure Programs (ORIP) in the Office of the Director at NIH. More than 50,000 mutant alleles are maintained as live mice, cryopreserved germplasm, and/or mutant ES cells. Live mice are supplied from a production colony, from a colony recovered from cryopreservation, or via micro-injection of ES cells. An MMRRC facility may offer cryopreserved material for resuscitation at the recipient scientist's institution.