|Alteration at locus: Non-mutant|
Donor: Andras Nagy, Ph.D., Mt. Sinai Hospital, Toronto
Nagy A, Rossant J, Nagy R, Abramow-Newerly W, Roder JC. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8424-8. (Medline PMID: 8378314 )
The Donating Investigator reports that this subclone of bulk R1 ES cells exhibits improved developmental potential compared to the standard R1 ES cell line.
Requested cell lines are tested by PCR analysis for mycoplasma spp. and Murine Parvoviruses (MPV) upon completion of expansion and prior to shipment. Mice derived from requested cell lines via Microinjection services will be pathogen tested prior to delivery of mice and health reports will be provided. If you require additional health status information prior to requesting microinjection please email firstname.lastname@example.org.
Cryo-preserved ES cell line material can usually be shipped in 2 to 4 weeks.
Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.
The donor or their institution limits the distribution to non-profit institutions only.
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