Strain Detail Sheet

Strain Name:
STOCK Mapttm1(EGFP)Klt Psen1tm1Mpm Tg(APPSwe,tauP301L)1Lfa /Mmjax CB012 mES cells
Stock Number:
037558-JAX
Citation ID:
RRID:MMRRC_037558-JAX
Other Names:
CB012

Gene Information

Gene Details

Mapttm1(EGFP)Klt
Name: microtubule-associated protein tau; targeted mutation 1, Kerry Lee Tucker
Synonyms: tauGFP, tau ko, Mapttm1(GFP)Klt
Type: Allele
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Knockout
Psen1tm1Mpm
Name: presenilin 1; targeted mutation 1, Mark P Mattson
Synonyms: PS1KI, PS1M146V, PS-1 M146V KI, PS1M146VKI-
Type: Allele
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Targeted Mutation
Tg(APPSwe,tauP301L)1Lfa
Name: transgene insertion 1, Frank M LaFerla
Synonyms: Tg(APP*Swe,MAPT*P301L)1Lfa
Type: Transgene
Species: Mus musculus (mouse)
Chromosome: unknown
Alteration at locus: Transgenic
Genotype Determination
  • Updated ES Cell information is included with the shipment.

Strain Origin

Donor
Laura Reinholdt, Ph.D., The Jackson Laboratory.
Primary Reference
Czechanski A, Byers C, Greenstein I, Schrode N, Donahue LR, Hadjantonakis AK, Reinholdt LG. Derivation and characterization of mouse embryonic stem cells from permissive and nonpermissive strains. Nat Protoc. 2014 Mar;9(3):559-74. (Medline PMID: 24504480)

Colony and Husbandry Information

Special Considerations

ES cells are expanded upon request and are usually ready for shipment in 3-5 weeks.

Health Status Report

Requested cell lines are tested by PCR analysis for mycoplasma spp. and Murine Parvoviruses (MPV) upon completion of expansion and prior to shipment.

Mice derived from requested cell lines via Microinjection services will be pathogen tested prior to delivery of mice and health reports will be provided. If you require additional health status information prior to requesting microinjection please email csmmrrc@jax.org.

Order Request Information

Conditions of Distribution

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Fees

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*		 Units Notes
037558-JAX-CELL STOCK Mapttm1(EGFP)Klt Psen1tm1Mpm Tg(APPSwe,tauP301L)1Lfa /Mmjax CB012 mES cells $546.00 / $546.00
Non-Profit / For-Profit		 Vial Includes genetic confirmation
To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.