New Video Series: Genetic Quality Control at the MMRRC

The MMRRC is pleased to announce a new series detailing our updated Genetic Quality Control process. These sessions provide insight into how we validate alleles and characterize genetic backgrounds, ensuring rigorous experimental design and robust study replicability. Watch individual videos at the link below, or watch the full series.

• What is Genetic Quality Control:

  Learn the core objectives of the Genetic Quality Control process. This introduction highlights the critical link between genetic background and phenotypic expression, demonstrating why allele validation is essential for reproducible research.

  https://youtu.be/23ypdpILgok?si=SvMHISjWo1zfnplW

• How to Read and Interpret a Report:

  A practical walkthrough of MMRRC’s Genetic Quality Control reports. This session demystifies technical data and metrics, enabling researchers to evaluate strain genetic status for specific experimental needs confidently.

  https://youtu.be/5fv2kReK0D0?si=HwSaAaXBfiQS1y8m

• Strain Classification:

  Explore the methodologies the MMRRC uses to accurately classify strains based on their genetic profiles. We discuss the bioinformatic standards that ensure nomenclature reflects the true genetic architecture.

  https://youtu.be/k_4I6ezH52k?si=WRr3quXUcWtyujEL

• Genetic Replicability:

  Examine the intersection of genetic background and study reproducibility. This video offers technical insights into establishing baseline expectations for genetic consistency to mitigate variables across longitudinal studies.

  https://youtu.be/a3Fvual4PLo?si=LAwKQz9YAFgwaEx1

• Collaborative Cross:

  Discover the specialized application of Genetic Quality Control within Collaborative Cross populations. This installment details the tailored strategies required to maintain genetic precision and stability in diverse, multi-parental models.

  https://youtu.be/xvkpNwSikr8?si=eFERL2otanLvWRH1