Homozygous: Mice are viable and fertile
Hemizygous: Mice are viable and fertile
Vaisman BL, Ghias M, Demosky SJ, Stonik JA, Amar MJ, Sampson M, Remaley AT. Role of endothelial expression of ABCA1 and SR-BI genes in HDL metabolism, cholesterol trafficking and protection against atherosclerosis. Abstract from AHA Scientific Sessions 2010, Chicago, IL.
|Viability and Fertility:||Female||Male||Comments|
|Homozygotes are viable:||Yes||Yes|
|Homozygotes are fertile:||Yes||Yes|
|Hetero/Hemizygotes are fertile:||Yes||Yes|
|Age Reproductive Decline:||6 months||6 months|
Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.