Strain Name:
C57BL/6J-MtgxP0026Btlr/Mmmh
Stock Number:
038279-MU
Citation ID:
RRID:MMRRC_038279-MU
Other Names:
P0026 (G1), C57BL/6J-MtgxP0026Btlr
Major Collection:

Gene Information

Trappc9
Name: trafficking protein particle complex 9
Synonyms: 4632408O18Rik, 2900005P22Rik, Nibp, TRS130, 1810044A24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 76510
VEGA: 15
Homologene: 81931
Ints8
Name: integrator complex subunit 8
Synonyms: D130008D20Rik, 2810013E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72656
Homologene: 9888
Abi2
Name: abl interactor 2
Synonyms: 8430425M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329165
Homologene: 4209
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: l(7)-3Rn, Ten-m4, Doc4, ELM2, l7Rn3, Odz4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 23966
Homologene: 8034
Dnpep
Name: aspartyl aminopeptidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13437
HGNC: HGNC:2981
Homologene: 6110
Dapk1
Name: death associated protein kinase 1
Synonyms: 2310039H24Rik, 2810425C21Rik, D13Ucla1, DAP-Kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 69635
VEGA: 13
HGNC: HGNC:2674
Homologene: 3626
Rap1gap2
Name: RAP1 GTPase activating protein 2
Synonyms: LOC380710, Garnl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380711
Homologene: 56695
Elf3
Name: E74-like factor 3
Synonyms: jen, ESX, ESE-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13710
HGNC: HGNC:3318
Homologene: 3265
Snx7
Name: sorting nexin 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76561
Homologene: 22941
Rusc2
Name: RUN and SH3 domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100213
Homologene: 18967
Gm10440
Name: predicted gene 10440
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330086
Acad10
Name: acyl-Coenzyme A dehydrogenase family, member 10
Synonyms: 2410021P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71985
Homologene: 49825
Cpa1
Name: carboxypeptidase A1, pancreatic
Synonyms: 0910001L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 109697
HGNC: HGNC:2296
Homologene: 55609
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Kcnu1
Name: potassium channel, subfamily U, member 1
Synonyms: Slo3, Kcnma3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16532
Homologene: 7392
Il12rb1
Name: interleukin 12 receptor, beta 1
Synonyms: IL-12R[b], CD212
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16161
HGNC: HGNC:5971
Homologene: 4042
Slc9a5
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 5
Synonyms: LOC277973
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 277973
Homologene: 31247
Bud13
Name: BUD13 homolog
Synonyms: D030060M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215051
Homologene: 13102
Zfp354a
Name: zinc finger protein 354A
Synonyms: kid1, Tcf17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21408
Homologene: 55921
Trim17
Name: tripartite motif-containing 17
Synonyms: terf, Rnf16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 56631
Homologene: 9387
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, 2900022L05Rik, Dnhd3, Dnahc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Mrm3
Name: mitochondrial rRNA methyltransferase 3
Synonyms: HC90, 4833420N02Rik, Rnmtl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67390
Homologene: 10033
Fam20a
Name: FAM20A, golgi associated secretory pathway pseudokinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 208659
Homologene: 9719
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, Cpfl8, diminished cone electroretinogram, dice
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Fam124a
Name: family with sequence similarity 124, member A
Synonyms: EG629059
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 629059
Homologene: 86241
Aifm3
Name: apoptosis-inducing factor, mitochondrion-associated 3
Synonyms: 2810401C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 72168
Homologene: 13773
Fermt3
Name: fermitin family member 3
Synonyms: C79673, Kindlin-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 108101
VEGA: 19
Homologene: 12877
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 60,453,723 bp
  • C to T, chromosome 1 at 75,308,685 bp
  • A to G, chromosome 1 at 135,255,973 bp
  • A to T, chromosome 3 at 117,840,023 bp
  • T to A, chromosome 4 at 11,225,788 bp
  • T to A, chromosome 4 at 43,415,840 bp
  • T to C, chromosome 5 at 54,356,169 bp
  • T to C, chromosome 5 at 121,637,352 bp
  • T to A, chromosome 6 at 30,640,906 bp
  • T to C, chromosome 7 at 96,874,527 bp
  • A to T, chromosome 7 at 105,758,405 bp
  • T to C, chromosome 8 at 25,892,122 bp
  • A to G, chromosome 8 at 70,812,541 bp
  • A to G, chromosome 8 at 105,355,291 bp
  • A to G, chromosome 9 at 46,288,358 bp
  • G to A, chromosome 11 at 51,061,498 bp
  • A to G, chromosome 11 at 58,971,258 bp
  • A to T, chromosome 11 at 69,464,947 bp
  • A to G, chromosome 11 at 74,567,210 bp
  • T to C, chromosome 11 at 76,247,500 bp
  • A to T, chromosome 11 at 109,675,841 bp
  • A to G, chromosome 12 at 75,880,220 bp
  • T to A, chromosome 13 at 60,718,149 bp
  • T to G, chromosome 14 at 62,606,122 bp
  • G to A, chromosome 15 at 72,953,082 bp
  • A to T, chromosome 16 at 17,507,117 bp
  • A to G, chromosome 19 at 7,014,424 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
(Deceased) Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for P0026 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038279-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.