Strain Name:
C57BL/6J-MtgxR0010Btlr/Mmmh
Stock Number:
038305-MU
Citation ID:
RRID:MMRRC_038305-MU
Other Names:
R0010 (G1), C57BL/6J-MtgxR0010Btlr
Major Collection:

Strain Information

Mitf
Name: melanogenesis associated transcription factor
Synonyms: bHLHe32, wh, Gsfbcc2, BCC2, mi
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17342
HGNC: HGNC:7105
Homologene: 4892
Shprh
Name: SNF2 histone linker PHD RING helicase
Synonyms: D230017O13Rik, 2610103K11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 268281
Homologene: 6489
Cd74
Name: CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
Synonyms: CLIP, Ii
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16149
VEGA: 18
HGNC: HGNC:1697
Homologene: 3209
Npr1
Name: natriuretic peptide receptor 1
Synonyms: guanylyl cyclase-A, NPRA, GC-A, NPR-A
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18160
HGNC: HGNC:7943
Homologene: 37367
Cacna1h
Name: calcium channel, voltage-dependent, T type, alpha 1H subunit
Synonyms: T-type Cav3.2, alpha13.2, Cav3.2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 58226
HGNC: HGNC:1395
Homologene: 56913
Glrb
Name: glycine receptor, beta subunit
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14658
HGNC: HGNC:4329
Homologene: 20224
Inpp5d
Name: inositol polyphosphate-5-phosphatase D
Synonyms: Src homology 2 domain-containing inositol-5-phosphatase, s-SHIP, SHIP-1, SHIP, SHIP1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16331
HGNC: HGNC:6079
Homologene: 4046
Ptprk
Name: protein tyrosine phosphatase receptor type K
Synonyms: RPTPkappa, PTPk
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Ylpm1
Name: YLP motif containing 1
Synonyms: Zap3, A930013E17Rik, ZAP
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56531
Homologene: 87707
Slc16a3
Name: solute carrier family 16 (monocarboxylic acid transporters), member 3
Synonyms: MCT3, MCT4, monocarboxylate transporter 4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 80879
Homologene: 37900
Adgrl3
Name: adhesion G protein-coupled receptor L3
Synonyms: lectomedin 3, 5430402I23Rik, D130075K09Rik, Lphn3, LEC3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319387
Homologene: 22878
Nek7
Name: NIMA (never in mitosis gene a)-related expressed kinase 7
Synonyms: 2810460C19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 59125
Homologene: 69340
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: nmf2, nur14, C630029C19Rik, seal, med, motor end-plate disease, ataxia 3, nmf335, mnd2, mnd-2, nmf58, NaCh6, NMF335, Nav1.6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20273
Homologene: 7927
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: D5Ertd66e, Bwf1, 2610509D04Rik, Bchs, Ggtb3, Alfy
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72145
Homologene: 22855
Naa15
Name: N(alpha)-acetyltransferase 15, NatA auxiliary subunit
Synonyms: Tbdn-1, ASTBDN, Narg1, mNAT1, 5730450D16Rik, tubedown
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74838
Homologene: 14211
Cdk5rap2
Name: CDK5 regulatory subunit associated protein 2
Synonyms: an, 2900018K03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 214444
Homologene: 49533
Txlna
Name: taxilin alpha
Synonyms: Txln, IL14, 2600010N21Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 109658
Homologene: 14062
Smg1
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase
Synonyms: SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans), C130002K18Rik, 5430435M13Rik, 2610207I05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233789
Homologene: 56697
Nup133
Name: nucleoporin 133
Synonyms: mermaid, 4832420O05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234865
Homologene: 32402
Mon2
Name: MON2 homolog, regulator of endosome to Golgi trafficking
Synonyms: SF21, 2610528O22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67074
VEGA: 10
Homologene: 44309
Dennd4c
Name: DENN domain containing 4C
Synonyms: 1700065A05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329877
Homologene: 23057
Sgk1
Name: serum/glucocorticoid regulated kinase 1
Synonyms: Sgk
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20393
Homologene: 48364
Trappc4
Name: trafficking protein particle complex 4
Synonyms: Sbdn, 1500017G03Rik, TRS23, Sbd, PTD009, HSPC172
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 60409
VEGA: 9
Homologene: 105453
Fam114a2
Name: family with sequence similarity 114, member A2
Synonyms: 9030624B09Rik, 1810073G14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67726
HGNC: HGNC:1333
Homologene: 10270
Rock1
Name: Rho-associated coiled-coil containing protein kinase 1
Synonyms: Rock-I, 1110055K06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 19877
VEGA: 18
Homologene: 55899
Fcho1
Name: FCH domain only 1
Synonyms: 3322402E17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74015
Homologene: 22869
Frem1
Name: Fras1 related extracellular matrix protein 1
Synonyms: heb, eyem02Jus, eyes2, QBRICK, crf11
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329872
Homologene: 27049
Mpdu1
Name: mannose-P-dolichol utilization defect 1
Synonyms: LEC35, SL15, Supl15h
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 24070
HGNC: HGNC:7207
Homologene: 3581
Pradc1
Name: protease-associated domain containing 1
Synonyms: 1700040I03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 73327
Homologene: 13008
Adgrf3
Name: adhesion G protein-coupled receptor F3
Synonyms: PGR23, Gpr113, LOC381628
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381628
Homologene: 17826
Ms4a4d
Name: membrane-spanning 4-domains, subfamily A, member 4D
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66607
Homologene: 113790
Nktr
Name: natural killer tumor recognition sequence
Synonyms: 5330401F18Rik, D9Wsu172e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18087
HGNC: HGNC:7833
Homologene: 122148
Dhx37
Name: DEAH-box helicase 37
Synonyms: LOC208144, LOC381671
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208144
Homologene: 6641
Itpr3
Name: inositol 1,4,5-triphosphate receptor 3
Synonyms: Ip3r3, Itpr-3, tf
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16440
HGNC: HGNC:6182
Homologene: 1675
Milr1
Name: mast cell immunoglobulin like receptor 1
Synonyms: LOC380732, Gm885, Allergin-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380732
Homologene: 86017
Ginm1
Name: glycoprotein integral membrane 1
Synonyms: BC013529
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215751
Homologene: 16347
Nlgn1
Name: neuroligin 1
Synonyms: 6330415N05Rik, NL1, Nlg1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192167
Homologene: 56690
Egfem1
Name: EGF-like and EMI domain containing 1
Synonyms: 6130401L20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 75740
Homologene: 135950
Spta1
Name: spectrin alpha, erythrocytic 1
Synonyms: Spna1, ihj, erythroid, Spna-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20739
Homologene: 74460
Zbtb41
Name: zinc finger and BTB domain containing 41
Synonyms: 9830132G07Rik, 8430415N23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226470
Homologene: 27795
Trappc14
Name: trafficking protein particle complex 14
Synonyms: BC037034, Map11
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231807
Homologene: 10106
Zfp608
Name: zinc finger protein 608
Synonyms: 4932417D18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 269023
VEGA: 18
Homologene: 18485
Myl3
Name: myosin, light polypeptide 3
Synonyms: ventricular, MLC1s, Mylc, alkali, MLC1v, slow skeletal
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17897
HGNC: HGNC:7584
Homologene: 20099
Ahrr
Name: aryl-hydrocarbon receptor repressor
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 11624
HGNC: HGNC:346
Homologene: 49215
Glt6d1
Name: glycosyltransferase 6 domain containing 1
Synonyms: 4933411C14Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71103
Homologene: 18826
Or5ak24
Name: olfactory receptor family 5 subfamily AK member 24
Synonyms: Olfr994, MOR203-4, GA_x6K02T2Q125-46907515-46906571
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258425
Homologene: 17245
Mybpc3
Name: myosin binding protein C, cardiac
Synonyms: cardiac C-protein
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17868
HGNC: HGNC:7551
Homologene: 215
Ccdc73
Name: coiled-coil domain containing 73
Synonyms: 2210415I11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 211936
Homologene: 52235
Bbs7
Name: Bardet-Biedl syndrome 7
Synonyms: 8430406N16Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71492
Homologene: 12395
Intu
Name: inturned planar cell polarity protein
Synonyms: Pdzk6, 9230116I04Rik, 9430087H23Rik, Pdzd6
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 380614
Homologene: 41059
Vmn2r6
Name: vomeronasal 2, receptor 6
Synonyms: EG667069, EG620718
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 667069
Homologene: 129754
Mcoln2
Name: mucolipin 2
Synonyms: mucolipidin 2, 3300002C04Rik, TRPML2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68279
Homologene: 12258
Pus7
Name: pseudouridylate synthase 7
Synonyms: C330017I15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 78697
Homologene: 6998
Evc2
Name: EvC ciliary complex subunit 2
Synonyms: limbin, Lbn, Ellis van Creveld syndrome 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68525
Homologene: 17117
Ube2d2b
Name: ubiquitin-conjugating enzyme E2D 2B
Synonyms: 1700013N18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 73318
Homologene: 134887
Zfp605
Name: zinc finger protein 605
Synonyms: A830023I12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 675812
Homologene: 52335
Aoc1l3
Name: amine oxidase copper containing 1-like 3
Synonyms: SVS I, Svs1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243377
HGNC: HGNC:80
Homologene: 18250
Igkv6-29
Name: immunoglobulin kappa chain variable 6-29
Synonyms: Gm16692
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 620191
HGNC: HGNC:5834
Kmt5c
Name: lysine methyltransferase 5C
Synonyms: Suv420h2, Suv4-20h2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232811
Homologene: 32792
Cyp2b9
Name: cytochrome P450, family 2, subfamily b, polypeptide 9
Synonyms: phenobarbitol inducible, type a, Cyp2b
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13094
HGNC: HGNC:2615
Homologene: 74933
Scgb2b26
Name: secretoglobin, family 2B, member 26
Synonyms: Scgb2b4, Abpg, C2d, Abpbg4, Abpbg26
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 110187
Homologene: 83171
Eif3f
Name: eukaryotic translation initiation factor 3, subunit F
Synonyms: Eif3s5, 0610037M02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66085
HGNC: HGNC:3275
Homologene: 2783
Gm3985
Name: predicted gene 3985
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 100042715
Ces2a
Name: carboxylesterase 2A
Synonyms: 9130231C15Rik, Ces6
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102022
HGNC: HGNC:1864
Homologene: 136396
Zfp469
Name: zinc finger protein 469
Synonyms: LOC195209, Gm22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 195209
Homologene: 18937
Or7g20
Name: olfactory receptor family 7 subfamily G member 20
Synonyms: MOR150-3, GA_x6K02T2PVTD-12771995-12772930, Olfr835
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 257872
HGNC: HGNC:8466
Homologene: 133702
Or8b42
Name: olfactory receptor family 8 subfamily B member 42
Synonyms: GA_x6K02T2PVTD-32123032-32123967, MOR162-8, Olfr901
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258028
VEGA: 9
Homologene: 79399
Dennd4a
Name: DENN domain containing 4A
Synonyms: F730015K02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102442
VEGA: 9
Homologene: 55933
Gm5422
Name: predicted pseudogene 5422
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 432448
VEGA: 10
Slc5a8
Name: solute carrier family 5 (iodide transporter), member 8
Synonyms: SMCT
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216225
VEGA: 10
Homologene: 64832
Nav3
Name: neuron navigator 3
Synonyms: Pomfil1p, 4732483H20Rik, 9630020C08Rik, steerin 3, unc53H3, POMFIL1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 260315
Homologene: 56688
Sec14l1
Name: SEC14-like lipid binding 1
Synonyms: 1200017E04Rik, 2810012L19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74136
Homologene: 37719
Sec61bl
Name: SEC61 translocon subunit beta like
Synonyms: Gm10320
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 101055909
Sec24c
Name: SEC24 homolog C, COPII coat complex component
Synonyms: 2610204K03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218811
VEGA: 14
Homologene: 3615
Lrp12
Name: low density lipoprotein-related protein 12
Synonyms: C820005L12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239393
Homologene: 8385
Zhx2
Name: zinc fingers and homeoboxes 2
Synonyms: Raf, Afr-1, Afr1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 387609
Homologene: 8968
Oc90
Name: otoconin 90
Synonyms: PLA2L, Ocn-95, Pla2ll
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18256
HGNC: HGNC:8100
Homologene: 19021
Fam135b
Name: family with sequence similarity 135, member B
Synonyms: 1700010C24Rik, A830008O07Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 70363
VEGA: 15
Homologene: 66605
Tubgcp6
Name: tubulin, gamma complex component 6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328580
Homologene: 32477
RP24-528G7.5
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Cldnd1
Name: claudin domain containing 1
Synonyms: 1110019C08Rik, Cldn25
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224250
HGNC: HGNC:1322
Homologene: 10534
Sema6b
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
Synonyms: Seman, Sema, VIb, semaZ
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20359
VEGA: 17
Homologene: 8428
Ltbp1
Name: latent transforming growth factor beta binding protein 1
Synonyms: 9430031G15Rik, LTBP-1, b2b1000Clo, Ltbp1L
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268977
HGNC: HGNC:6714
Homologene: 522
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 87,697,546 bp
  • T to A, chromosome 1 at 138,544,204 bp
  • T to G, chromosome 1 at 139,423,530 bp
  • G to A, chromosome 1 at 174,217,943 bp
  • C to A, chromosome 2 at 25,794,727 bp
  • A to T, chromosome 2 at 85,429,895 bp
  • G to A, chromosome 2 at 91,134,833 bp
  • C to T, chromosome 2 at 104,980,987 bp
  • G to T, chromosome 3 at 25,435,842 bp
  • G to T, chromosome 3 at 29,582,919 bp
  • T to C, chromosome 3 at 36,607,717 bp
  • T to C, chromosome 3 at 40,654,272 bp
  • A to T, chromosome 3 at 51,436,213 bp
  • G to A, chromosome 3 at 64,559,545 bp
  • A to T, chromosome 3 at 80,860,315 bp
  • T to C, chromosome 3 at 90,454,832 bp
  • C to T, chromosome 3 at 146,183,561 bp
  • T to C, chromosome 4 at 70,243,459 bp
  • T to C, chromosome 4 at 83,000,098 bp
  • T to C, chromosome 4 at 86,781,577 bp
  • T to G, chromosome 4 at 129,629,086 bp
  • T to C, chromosome 5 at 23,747,845 bp
  • T to C, chromosome 5 at 30,205,609 bp
  • T to A, chromosome 5 at 37,417,449 bp
  • C to T, chromosome 5 at 81,792,403 bp
  • T to C, chromosome 5 at 101,848,349 bp
  • T to C, chromosome 5 at 107,830,636 bp
  • T to A, chromosome 5 at 110,127,534 bp
  • T to A, chromosome 5 at 125,431,616 bp
  • T to C, chromosome 5 at 138,260,293 bp
  • A to T, chromosome 6 at 48,988,906 bp
  • A to T, chromosome 6 at 70,138,770 bp
  • A to T, chromosome 6 at 85,447,231 bp
  • T to C, chromosome 6 at 85,447,620 bp
  • A to G, chromosome 6 at 97,807,281 bp
  • T to A, chromosome 7 at 4,746,208 bp
  • T to A, chromosome 7 at 26,186,753 bp
  • T to A, chromosome 7 at 33,944,349 bp
  • A to T, chromosome 7 at 108,941,005 bp
  • A to T, chromosome 7 at 118,171,859 bp
  • A to T, chromosome 8 at 32,942,456 bp
  • A to G, chromosome 8 at 71,709,999 bp
  • G to A, chromosome 8 at 104,741,396 bp
  • G to A, chromosome 8 at 122,270,598 bp
  • A to T, chromosome 8 at 123,904,579 bp
  • A to T, chromosome 9 at 19,035,322 bp
  • A to T, chromosome 9 at 38,430,920 bp
  • G to A, chromosome 9 at 44,405,231 bp
  • T to C, chromosome 9 at 64,896,715 bp
  • A to C, chromosome 9 at 110,767,929 bp
  • G to A, chromosome 9 at 121,741,166 bp
  • T to C, chromosome 10 at 7,775,374 bp
  • C to T, chromosome 10 at 11,151,931 bp
  • G to A, chromosome 10 at 21,997,438 bp
  • G to A, chromosome 10 at 28,585,969 bp
  • A to G, chromosome 10 at 31,249,754 bp
  • T to C, chromosome 10 at 88,886,590 bp
  • A to G, chromosome 10 at 109,823,226 bp
  • A to C, chromosome 10 at 123,032,694 bp
  • G to T, chromosome 11 at 57,514,156 bp
  • C to T, chromosome 11 at 69,658,841 bp
  • T to G, chromosome 11 at 106,767,003 bp
  • T to C, chromosome 11 at 117,143,770 bp
  • T to C, chromosome 11 at 120,956,705 bp
  • C to A, chromosome 12 at 85,029,026 bp
  • G to A, chromosome 13 at 74,283,024 bp
  • T to C, chromosome 13 at 98,489,546 bp
  • A to G, chromosome 14 at 20,689,261 bp
  • C to T, chromosome 15 at 39,878,276 bp
  • T to C, chromosome 15 at 57,821,274 bp
  • C to T, chromosome 15 at 65,876,548 bp
  • T to C, chromosome 15 at 71,622,032 bp
  • A to G, chromosome 15 at 89,103,183 bp
  • T to C, chromosome 15 at 101,013,573 bp
  • T to A, chromosome 16 at 38,347,170 bp
  • T to A, chromosome 16 at 58,731,259 bp
  • T to C, chromosome 17 at 25,380,844 bp
  • T to G, chromosome 17 at 27,120,977 bp
  • C to T, chromosome 17 at 56,124,105 bp
  • A to G, chromosome 17 at 75,363,391 bp
  • T to A, chromosome 18 at 10,084,380 bp
  • A to T, chromosome 18 at 54,895,214 bp
  • A to T, chromosome 18 at 60,803,896 bp
  • A to T, chromosome 18 at 60,809,071 bp
  • A to G, chromosome 19 at 11,554,826 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0010 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038305-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.