Strain Name:
C57BL/6J-MtgxR0011Btlr/Mmmh
Stock Number:
038306-MU
Citation ID:
RRID:MMRRC_038306-MU
Other Names:
R0011 (G1), C57BL/6J-MtgxR0011Btlr
Major Collection:

Gene Information

Tyrp1
Name: tyrosinase-related protein 1
Synonyms: isa, TRP1, Tyrp, Oca3, TRP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22178
Homologene: 464
Sema3e
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Synonyms: Semah
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20349
Homologene: 8247
Igf2bp1
Name: insulin-like growth factor 2 mRNA binding protein 1
Synonyms: IMP1, D030026A21Rik, Crdbp, D11Moh40e, D11Moh45, Zbp1, IMP-1, CRD-BP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 140486
Homologene: 4772
Epha7
Name: Eph receptor A7
Synonyms: Ebk, Mdk1, MDK1, Hek11, Ehk3, Cek11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13841
HGNC: HGNC:3390
Homologene: 20935
Spidr
Name: scaffolding protein involved in DNA repair
Synonyms: 2310008H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224008
VEGA: 16
Homologene: 51693
Cops4
Name: COP9 signalosome subunit 4
Synonyms: COP9 complex S4, D5Ertd774e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26891
Homologene: 8067
Diaph3
Name: diaphanous related formin 3
Synonyms: Drf3, Diap3, p134MDia2, 4930417P13Rik, mDia2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56419
VEGA: 14
Homologene: 84829
Hnrnpul1
Name: heterogeneous nuclear ribonucleoprotein U-like 1
Synonyms: Hnrpul1, Hnrnpul, E1B-AP5, E1BAP5, E130317O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232989
Homologene: 31419
Msh2
Name: mutS homolog 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17685
HGNC: HGNC:7325
Homologene: 210
Cyb5a
Name: cytochrome b5 type A (microsomal)
Synonyms: Cyb5, 0610009N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 109672
HGNC: HGNC:2570
Homologene: 41475
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, Lek1, mitosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Ank3
Name: ankyrin 3, epithelial
Synonyms: 2900054D09Rik, Ank-3, AnkG, Ankyrin-3, Ankyrin-G
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: Garnl1, Tulip1, 4930400K19Rik, 2310003F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56784
VEGA: 12
Homologene: 84805
Grin2c
Name: glutamate receptor, ionotropic, NMDA2C (epsilon 3)
Synonyms: NR2C, GluRepsilon3, NMDAR2C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14813
HGNC: HGNC:4587
Homologene: 647
Slc39a11
Name: solute carrier family 39 (metal ion transporter), member 11
Synonyms: 1810074D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69806
Homologene: 12331
Epg5
Name: ectopic P-granules autophagy protein 5 homolog (C. elegans)
Synonyms: 5430411K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 100502841
VEGA: 18
Homologene: 14575
Mtr
Name: 5-methyltetrahydrofolate-homocysteine methyltransferase
Synonyms: D830038K18Rik, MS, methionine synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238505
VEGA: 13
HGNC: HGNC:7468
Homologene: 37280
Ccdc88a
Name: coiled coil domain containing 88A
Synonyms: GIV, A430106J12Rik, C130096N06Rik, C330012F17Rik, D130005J21Rik, HkRP1, Girdin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 108686
Homologene: 41180
Brip1
Name: BRCA1 interacting protein C-terminal helicase 1
Synonyms: BACH1, 3110009N10Rik, 8030460J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237911
Homologene: 32766
Enpp1
Name: ectonucleotide pyrophosphatase/phosphodiesterase 1
Synonyms: Pdnp1, PC-1, 4833416E15Rik, twy, E-NPP1, Pca-1, Pca, NPP1, Ly-41, CD203c, Npps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18605
HGNC: HGNC:3356
Homologene: 38151
Wscd1
Name: WSC domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216881
Homologene: 18590
Rasgef1b
Name: RasGEF domain family, member 1B
Synonyms: 4732452O09Rik, Gpig4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320292
Homologene: 14860
Ncoa1
Name: nuclear receptor coactivator 1
Synonyms: steroid receptor coactivator-1, bHLHe74, SRC1, SRC-1, KAT13A, SRC-a/NCoA-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 17977
VEGA: 12
HGNC: HGNC:7668
Homologene: 7859
Trim55
Name: tripartite motif-containing 55
Synonyms: Murf2, D830041C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 381485
Homologene: 13205
Shtn1
Name: shootin 1
Synonyms: shootin1, 4930506M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 71653
VEGA: 19
Homologene: 41249
Ttn
Name: titin
Synonyms: D330041I19Rik, mdm, L56, connectin, 2310074I15Rik, 2310057K23Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Kidins220
Name: kinase D-interacting substrate 220
Synonyms: 3110039L19Rik, C330002I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 77480
VEGA: 12
Homologene: 14254
Miox
Name: myo-inositol oxygenase
Synonyms: RSOR, Aldrl6, C85427, 0610009I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 56727
Homologene: 9732
Chia1
Name: chitinase, acidic 1
Synonyms: AMCase, 2200003E03Rik, YNL, Chia
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 81600
Homologene: 75168
Mrc1
Name: mannose receptor, C type 1
Synonyms: MR, CD206
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17533
HGNC: HGNC:7228
Homologene: 37622
Snapc4
Name: small nuclear RNA activating complex, polypeptide 4
Synonyms: 5730436L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227644
Homologene: 2321
G6pc2
Name: glucose-6-phosphatase, catalytic, 2
Synonyms: G6pc-rs, IGRP, islet specific glucose-6-phosphatase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14378
Homologene: 41423
Ttc30a2
Name: tetratricopeptide repeat domain 30A2
Synonyms: OTTMUSG00000015167
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 620631
Homologene: 44342
Trp53i11
Name: transformation related protein 53 inducible protein 11
Synonyms: Tp53i11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 277414
Homologene: 4404
Ncoa6
Name: nuclear receptor coactivator 6
Synonyms: RAP250, PRIP, ASC2, ASC-2, AIB3, NRC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56406
Homologene: 137337
Insrr
Name: insulin receptor-related receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 23920
HGNC: HGNC:6093
Homologene: 56539
Celsr2
Name: cadherin, EGF LAG seven-pass G-type receptor 2
Synonyms: flamingo, mfmi1, EGFL2, Adgrc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 53883
HGNC: HGNC:3231
Homologene: 1078
D130062J21Rik
Name: RIKEN cDNA D130062J21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Tnfrsf1b
Name: tumor necrosis factor receptor superfamily, member 1b
Synonyms: p75, TNFRII, TNF-R2, TNFalpha-R2, TNF-alphaR2, CD120b, p75 TNFR, TNF-R75, TNFBR, TNF-R-II, Tnfr2, TNFR80
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21938
Homologene: 829
Asic3
Name: acid-sensing (proton-gated) ion channel 3
Synonyms: DRASIC, Accn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 171209
HGNC: HGNC:101
Homologene: 20999
Gm7361
Name: predicted gene 7361
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 664837
Homologene: 69402
Art3
Name: ADP-ribosyltransferase 3
Synonyms: 4930569O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 109979
HGNC: HGNC:725
Homologene: 911
Casc1
Name: cancer susceptibility candidate 1
Synonyms: A230084G12Rik, Las1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320662
Homologene: 41242
Klk1
Name: kallikrein 1
Synonyms: mGk-6, 0610007D04Rik, Klk6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16612
Homologene: 68141
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Cdcp3
Name: CUB domain containing protein 3
Synonyms: 5430419D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71395
Homologene: 138430
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244484
Homologene: 12460
Mbd3l1
Name: methyl-CpG binding domain protein 3-like 1
Synonyms: 1700070G05Rik, Mbd3l, 1700095H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73503
VEGA: 9
Homologene: 12502
Olfr965
Name: olfactory receptor 965
Synonyms: GA_x6K02T2PVTD-33416730-33417668, MOR171-28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258165
VEGA: 9
Tmem202
Name: transmembrane protein 202
Synonyms: 4930425N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73893
VEGA: 9
Homologene: 52264
Pik3r4
Name: phosphoinositide-3-kinase regulatory subunit 4
Synonyms: Vps15, p150
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75669
HGNC: HGNC:8982
Homologene: 24678
Gm872
Name: predicted gene 872
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Rdh19
Name: retinol dehydrogenase 19
Synonyms: Rdhs, RDH-S
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216453
Homologene: 129514
Trim58
Name: tripartite motif-containing 58
Synonyms: LOC216781, LOC386443
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216781
Homologene: 9135
Alox15
Name: arachidonate 15-lipoxygenase
Synonyms: 12-LO, L-12LO, Alox12l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11687
HGNC: HGNC:433
Homologene: 44935
Krt35
Name: keratin 35
Synonyms: Ha5, Krt1-24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53617
HGNC: HGNC:6453
Homologene: 1715
Slc4a1
Name: solute carrier family 4 (anion exchanger), member 1
Synonyms: l11Jus51, erythrocyte membrane protein band 3, Ae1, Empb3, band 3, CD233
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20533
Homologene: 133556
Slc6a18
Name: solute carrier family 6 (neurotransmitter transporter), member 18
Synonyms: D630001K16Rik, Xtrp2, XT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 22598
VEGA: 13
Homologene: 40785
Npy4r
Name: neuropeptide Y receptor Y4
Synonyms: Ppyr1, Y4, NYYR-D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19065
VEGA: 14
HGNC: HGNC:9329
Homologene: 38119
Zfp251
Name: zinc finger protein 251
Synonyms: 9130001M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71591
VEGA: 15
Homologene: 87789
Itgb2l
Name: integrin beta 2-like
Synonyms: pactolus, 5033406G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16415
Emilin2
Name: elastin microfibril interfacer 2
Synonyms: FOAP-10, basilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 246707
VEGA: 17
Homologene: 36483
Pcdhgb8
Name: protocadherin gamma subfamily B, 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93705
Homologene: 81868
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 189,650,706 bp
  • T to C, chromosome 2 at 14,261,337 bp
  • A to G, chromosome 2 at 26,364,813 bp
  • C to A, chromosome 2 at 69,226,565 bp
  • T to A, chromosome 2 at 75,976,217 bp
  • T to C, chromosome 2 at 76,810,355 bp
  • A to T, chromosome 2 at 93,199,353 bp
  • TGC to TGCGC, chromosome 2 at 155,408,291 bp
  • A to G, chromosome 3 at 19,670,999 bp
  • T to C, chromosome 3 at 87,809,616 bp
  • A to G, chromosome 3 at 106,130,974 bp
  • A to G, chromosome 3 at 108,413,402 bp
  • G to A, chromosome 4 at 28,962,564 bp
  • G to T, chromosome 4 at 32,244,655 bp
  • C to T, chromosome 4 at 80,840,793 bp
  • T to G, chromosome 4 at 145,222,966 bp
  • C to T, chromosome 5 at 14,144,011 bp
  • C to T, chromosome 5 at 24,417,492 bp
  • C to T, chromosome 5 at 26,258,878 bp
  • T to A, chromosome 5 at 92,403,612 bp
  • T to C, chromosome 5 at 99,232,354 bp
  • C to A, chromosome 5 at 100,527,981 bp
  • T to A, chromosome 6 at 145,179,055 bp
  • T to G, chromosome 7 at 25,742,915 bp
  • C to T, chromosome 7 at 44,229,535 bp
  • T to C, chromosome 7 at 120,019,701 bp
  • T to A, chromosome 7 at 131,229,993 bp
  • A to T, chromosome 8 at 54,672,501 bp
  • A to G, chromosome 9 at 18,484,567 bp
  • T to A, chromosome 9 at 39,719,627 bp
  • T to A, chromosome 9 at 59,524,801 bp
  • C to A, chromosome 9 at 105,644,637 bp
  • T to A, chromosome 10 at 24,670,002 bp
  • A to G, chromosome 10 at 69,979,451 bp
  • A to T, chromosome 10 at 93,065,225 bp
  • T to A, chromosome 10 at 127,856,911 bp
  • T to C, chromosome 11 at 29,374,364 bp
  • A to T, chromosome 11 at 58,643,120 bp
  • A to G, chromosome 11 at 70,349,596 bp
  • T to C, chromosome 11 at 71,788,828 bp
  • C to A, chromosome 11 at 86,186,998 bp
  • T to C, chromosome 11 at 96,005,584 bp
  • T to A, chromosome 11 at 100,093,676 bp
  • T to C, chromosome 11 at 102,357,110 bp
  • A to T, chromosome 11 at 113,247,833 bp
  • T to C, chromosome 11 at 115,255,750 bp
  • A to C, chromosome 12 at 4,322,896 bp
  • T to A, chromosome 12 at 24,999,352 bp
  • A to G, chromosome 12 at 55,786,263 bp
  • T to C, chromosome 13 at 12,238,052 bp
  • A to T, chromosome 13 at 73,665,619 bp
  • C to T, chromosome 14 at 34,146,723 bp
  • A to T, chromosome 14 at 86,866,408 bp
  • A to G, chromosome 15 at 76,854,554 bp
  • C to T, chromosome 15 at 89,336,274 bp
  • A to T, chromosome 16 at 15,966,603 bp
  • T to C, chromosome 16 at 96,427,661 bp
  • C to T, chromosome 17 at 71,273,868 bp
  • T to C, chromosome 17 at 87,680,093 bp
  • T to C, chromosome 18 at 37,764,282 bp
  • T to C, chromosome 18 at 77,948,483 bp
  • T to A, chromosome 18 at 84,877,822 bp
  • A to G, chromosome 19 at 59,032,218 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0011 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038306-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.