Strain Name:
C57BL/6J-MtgxR0026Btlr/Mmmh
Stock Number:
038321-MU
Citation ID:
RRID:MMRRC_038321-MU
Other Names:
R0026 (G1), C57BL/6J-MtgxR0026Btlr
Major Collection:

Gene Information

Gene Symbol: Ntf3 (Mus musculus (mouse))
Name: neurotrophin 3
Synonyms: NT3, NT-3, Ntf-3
Chromosome: 6
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:97380
Gene Symbol: Utrn (Mus musculus (mouse))
Name: utrophin
Synonyms: G-utrophin, DRP, Dmdl
Chromosome: 10
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:104631
Gene Symbol: Atrn (Mus musculus (mouse))
Name: attractin
Synonyms: Mgca
Chromosome: 2
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:1341628
Gene Symbol: Ncor1 (Mus musculus (mouse))
Name: nuclear receptor co-repressor 1
Synonyms: A230020K14Rik, 5730405M06Rik, Rxrip13, N-CoR
Chromosome: 11
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:1349717
Gene Symbol: Pds5b (Mus musculus (mouse))
Name: PDS5 cohesin associated factor B
Synonyms: Aprin, WAP-Her-2, Tg(Wap-ERBB2)229Wzw, AS3, Her-2 Tg
Chromosome: 5
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:2140945
Gene Symbol: Trim6 (Mus musculus (mouse))
Name: tripartite motif-containing 6
Synonyms: C430046K18Rik, D7Ertd684e
Chromosome: 7
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:2137352
Gene Symbol: Dock5 (Mus musculus (mouse))
Name: dedicator of cytokinesis 5
Synonyms: lr2, rlc, 1110060D06Rik
Chromosome: 14
Alteration at locus: Chemically Induced
Monarch Initiative (Disease and Phenotype Associations): MGI:2652871
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 26,683,369 bp
  • T to A, chromosome 1 at 31,203,443 bp
  • A to G, chromosome 1 at 38,203,893 bp
  • T to A, chromosome 1 at 38,991,280 bp
  • C to A, chromosome 1 at 66,521,584 bp
  • C to T, chromosome 1 at 171,274,261 bp
  • T to C, chromosome 1 at 172,219,400 bp
  • T to C, chromosome 1 at 188,976,621 bp
  • T to C, chromosome 2 at 26,281,353 bp
  • T to A, chromosome 2 at 29,071,349 bp
  • T to C, chromosome 2 at 76,769,190 bp
  • A to G, chromosome 2 at 91,175,708 bp
  • T to C, chromosome 2 at 98,663,909 bp
  • T to C, chromosome 2 at 130,957,920 bp
  • T to C, chromosome 3 at 135,591,573 bp
  • T to A, chromosome 3 at 138,066,805 bp
  • A to G, chromosome 3 at 141,870,733 bp
  • G to A, chromosome 3 at 154,240,270 bp
  • A to C, chromosome 4 at 9,601,361 bp
  • T to A, chromosome 4 at 107,345,160 bp
  • A to T, chromosome 4 at 113,546,468 bp
  • C to T, chromosome 4 at 115,647,521 bp
  • A to T, chromosome 4 at 118,384,772 bp
  • A to G, chromosome 4 at 118,542,073 bp
  • A to G, chromosome 4 at 126,031,884 bp
  • G to A, chromosome 4 at 149,634,796 bp
  • C to T, chromosome 5 at 76,606,734 bp
  • T to A, chromosome 5 at 96,838,401 bp
  • G to A, chromosome 5 at 150,749,830 bp
  • G to T, chromosome 6 at 113,597,691 bp
  • A to G, chromosome 6 at 124,837,417 bp
  • T to A, chromosome 6 at 126,101,805 bp
  • T to A, chromosome 7 at 3,639,668 bp
  • T to G, chromosome 7 at 42,275,474 bp
  • T to C, chromosome 7 at 48,447,204 bp
  • T to A, chromosome 7 at 48,482,023 bp
  • T to C, chromosome 7 at 63,735,801 bp
  • T to C, chromosome 7 at 80,311,061 bp
  • C to A, chromosome 7 at 100,850,221 bp
  • T to A, chromosome 7 at 104,225,809 bp
  • C to T, chromosome 7 at 120,477,923 bp
  • A to G, chromosome 7 at 120,780,211 bp
  • T to A, chromosome 7 at 128,270,053 bp
  • T to A, chromosome 8 at 13,759,130 bp
  • C to T, chromosome 8 at 14,727,363 bp
  • C to T, chromosome 8 at 27,200,248 bp
  • G to A, chromosome 8 at 70,914,638 bp
  • A to G, chromosome 8 at 71,566,573 bp
  • A to G, chromosome 8 at 119,410,435 bp
  • T to C, chromosome 8 at 119,604,236 bp
  • T to A, chromosome 9 at 15,308,648 bp
  • A to G, chromosome 9 at 32,476,584 bp
  • G to A, chromosome 9 at 38,775,596 bp
  • A to T, chromosome 9 at 53,376,479 bp
  • A to T, chromosome 9 at 64,235,371 bp
  • A to G, chromosome 9 at 85,690,303 bp
  • A to G, chromosome 9 at 119,522,566 bp
  • T to C, chromosome 10 at 12,726,196 bp
  • A to T, chromosome 10 at 60,774,592 bp
  • T to C, chromosome 11 at 3,426,617 bp
  • G to T, chromosome 11 at 46,136,259 bp
  • T to C, chromosome 11 at 62,438,429 bp
  • T to C, chromosome 11 at 85,032,074 bp
  • T to C, chromosome 11 at 95,390,642 bp
  • T to A, chromosome 12 at 58,212,858 bp
  • G to A, chromosome 12 at 115,312,287 bp
  • T to C, chromosome 12 at 117,689,161 bp
  • C to T, chromosome 13 at 48,514,372 bp
  • T to C, chromosome 13 at 55,477,784 bp
  • C to T, chromosome 14 at 20,531,768 bp
  • A to T, chromosome 14 at 55,942,164 bp
  • C to A, chromosome 14 at 67,846,081 bp
  • G to A, chromosome 15 at 20,666,236 bp
  • T to C, chromosome 15 at 35,923,301 bp
  • T to C, chromosome 15 at 37,953,741 bp
  • T to C, chromosome 15 at 77,084,157 bp
  • T to C, chromosome 15 at 98,076,668 bp
  • A to G, chromosome 16 at 21,214,917 bp
  • T to C, chromosome 16 at 45,640,367 bp
  • T to C, chromosome 17 at 36,641,527 bp
  • T to A, chromosome 17 at 37,466,803 bp
  • T to A, chromosome 17 at 43,594,930 bp
  • G to A, chromosome X at 123,029,542 bp
Genotype Determination
ES Cell Line
N/A
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
MeSH Terms
    Strain Development
    C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
    Suggested Control Mice
    Wild-type littermates or C57BL/6J mice
    Primary Reference
    MUTAGENETIX record for R0026 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

    Colony and Husbandry Information

    Colony Surveillance Program and Current Health Reports

    Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
    Coat Color
    Black
    MMRRC Breeding System
    Random intra-strain mating
    Breeding Scheme(s)
    When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
    Overall Breeding Performance
    Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
    Average litter size
    Undetermined
    Recommended wean age
    3 weeks

    Order Request Information

    Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

    Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

    The donor or their institution limits the distribution to non-profit institutions only.

    Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

    Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
    MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
    038321-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.

    Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

    1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

    2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

    3 An aliquot contains a sufficient number of embryos (in one or more vials and based on the transfer success rate of the MMRRC facility) to transfer to at least two recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

    To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.