Strain Name:
C57BL/6J-MtgxR0097Btlr/Mmmh
Stock Number:
038383-MU
Citation ID:
RRID:MMRRC_038383-MU
Other Names:
R0097 (G1), C57BL/6J-MtgxR0097Btlr
Major Collection:

Gene Information

Zmpste24
Name: zinc metallopeptidase, STE24
Synonyms: A530043O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230709
Homologene: 4277
Ncam2
Name: neural cell adhesion molecule 2
Synonyms: RNCAM, R4B12 antigen, Ncam-2, Ocam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17968
HGNC: HGNC:7657
Homologene: 3336
Ubp1
Name: upstream binding protein 1
Synonyms: NF2d9, LBP-1b, LBP-1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22221
VEGA: 9
Homologene: 8435
Llgl2
Name: LLGL2 scribble cell polarity complex component
Synonyms: 9130006H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217325
HGNC: HGNC:6629
Homologene: 3323
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Baz1b
Name: bromodomain adjacent to zinc finger domain, 1B
Synonyms: Wbscr9, WSTF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22385
HGNC: HGNC:961
Homologene: 22651
Dab2ip
Name: disabled 2 interacting protein
Synonyms: 2310011D08Rik, AIP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69601
Homologene: 13058
Arfgap2
Name: ADP-ribosylation factor GTPase activating protein 2
Synonyms: 2310032E02Rik, Zfp289
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77038
Homologene: 8735
Rbbp5
Name: retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit
Synonyms: 4933411J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213464
HGNC: HGNC:9888
Homologene: 3709
Tppp3
Name: tubulin polymerization-promoting protein family member 3
Synonyms: 2700055K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67971
Homologene: 32659
Secisbp2l
Name: SECIS binding protein 2-like
Synonyms: 3110001I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70354
Homologene: 18923
Rab5b
Name: RAB5B, member RAS oncogene family
Synonyms: C030027M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19344
VEGA: 10
HGNC: HGNC:9784
Homologene: 104027
Neo1
Name: neogenin
Synonyms: D930014N22Rik, 2610028H22Rik, Igdcc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18007
VEGA: 9
HGNC: HGNC:7754
Homologene: 1870
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: l(7)-3Rn, Ten-m4, Doc4, ELM2, l7Rn3, Odz4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 23966
Homologene: 8034
Tgfbr1
Name: transforming growth factor, beta receptor I
Synonyms: TbetaR-I, TbetaRI, ALK5, Alk-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21812
Homologene: 3177
Vav2
Name: vav 2 oncogene
Synonyms: 2810040F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22325
Homologene: 2530
Lzic
Name: leucine zipper and CTNNBIP1 domain containing
Synonyms: 1810030J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69151
Homologene: 12301
Mtfr2
Name: mitochondrial fission regulator 2
Synonyms: 4933412C16Rik, 2610016C23Rik, Fam54a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71804
VEGA: 10
Homologene: 69441
Ddx41
Name: DEAD box helicase 41
Synonyms: 2900024F02Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72935
VEGA: 13
Homologene: 9431
Pnp
Name: purine-nucleoside phosphorylase
Synonyms: Np-2, Np-1, Np, Pnp, Pnp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18950
HGNC: HGNC:7892
Homologene: 227
Prss38
Name: protease, serine 38
Synonyms: LOC216797, Gm249
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216797
Homologene: 18831
Plpp2
Name: phospholipid phosphatase 2
Synonyms: Lpp2, Ppap2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 50784
HGNC: HGNC:9230
Homologene: 2752
Cldnd1
Name: claudin domain containing 1
Synonyms: 1110019C08Rik, Cldn25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224250
HGNC: HGNC:1322
Homologene: 10534
Ushbp1
Name: USH1 protein network component harmonin binding protein 1
Synonyms: MCC2, 2210404N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234395
Homologene: 12914
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Cacna1s
Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Synonyms: Cchl1a3, fmd, mdg, sj, muscle dysgenesis, Cav1.1, DHPR alpha1s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12292
HGNC: HGNC:1397
Homologene: 37257
Slc3a1
Name: solute carrier family 3, member 1
Synonyms: NTAA, D2H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20532
VEGA: 17
Homologene: 37289
Rhox4f
Name: reproductive homeobox 4F
Synonyms: Rhox4.6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 636177
Homologene: 79553
Mprip
Name: myosin phosphatase Rho interacting protein
Synonyms: RIP3, p116Rip, p116 Rho interacting protein, Rhoip3, Gm34094
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 26936
Homologene: 9034
Pnp2
Name: purine-nucleoside phosphorylase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 667034
HGNC: HGNC:7892
Homologene: 227
Eml3
Name: echinoderm microtubule associated protein like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225898
VEGA: 19
Homologene: 27044
Svs3b
Name: seminal vesicle secretory protein 3B
Synonyms: SVS III, 9530004A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329557
Homologene: 110771
Myocd
Name: myocardin
Synonyms: Srfcp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 214384
Homologene: 17043
Gm9938
Name: predicted gene 9938
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Pign
Name: phosphatidylinositol glycan anchor biosynthesis, class N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 27392
HGNC: HGNC:8967
Homologene: 6330
Neu2
Name: neuraminidase 2
Synonyms: brain sialidase, cystolic sialidase, MSS, MBS, MTS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 23956
HGNC: HGNC:7759
Homologene: 3927
Krt81
Name: keratin 81
Synonyms: Krt2-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 64818
VEGA: 15
HGNC: HGNC:6458
Homologene: 55645
1700006A11Rik
Name: RIKEN cDNA 1700006A11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71824
Nol4
Name: nucleolar protein 4
Synonyms: 4930568N03Rik, LOC383304, 1700013J13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 319211
HGNC: HGNC:7870
Homologene: 36142
St6galnac6
Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Synonyms: ST6GalNAcVI, Siat7f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 50935
Homologene: 8390
Olfr1025-ps1
Name: olfactory receptor 1025, pseudogene 1
Synonyms: GA_x6K02T2Q125-47397266-47398205, MOR196-5P, MOR196-6_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258083
Gpr87
Name: G protein-coupled receptor 87
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 84111
HGNC: HGNC:4538
Homologene: 13021
Dmrta1
Name: doublesex and mab-3 related transcription factor like family A1
Synonyms: Dmrt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242523
Homologene: 18477
Padi6
Name: peptidyl arginine deiminase, type VI
Synonyms: ePAD, Padi5, Pad6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242726
Homologene: 17695
Pramel30
Name: PRAME like 30
Synonyms: Gm13128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 626995
Homologene: 129642
Albfm1
Name: albumin superfamily member 1
Synonyms: ARG, Gm17754, 5830473C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 622307
Homologene: 129803
Ccnd2
Name: cyclin D2
Synonyms: Vin-1, Vin1, 2600016F06Rik, cD2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12444
HGNC: HGNC:1583
Homologene: 37525
Bbs10
Name: Bardet-Biedl syndrome 10 (human)
Synonyms: 1300007O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71769
VEGA: 10
Homologene: 49781
Sh3pxd2b
Name: SH3 and PX domains 2B
Synonyms: G431001E03Rik, Fad49, Tks4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268396
Homologene: 27952
Gm11627
Name: predicted gene 11627
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100040792
Rsl1
Name: regulator of sex limited protein 1
Synonyms: rslcan-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 380855
Homologene: 110878
T
Name: brachyury, T-box transcription factor T
Synonyms: T1, Bra, Tbxt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20997
Homologene: 2393
Vmn1r228
Name: vomeronasal 1 receptor 228
Synonyms: V1re3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 171226
Homologene: 74320
Ciao3
Name: cytosolic iron-sulfur assembly component 3
Synonyms: 9030612I22Rik, Narfl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67563
Homologene: 6750
Cyp2c54
Name: cytochrome P450, family 2, subfamily c, polypeptide 54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 404195
VEGA: 19
Homologene: 137231
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 87,597,466 bp
  • G to A, chromosome 1 at 105,587,976 bp
  • T to A, chromosome 1 at 132,490,489 bp
  • T to A, chromosome 1 at 136,100,622 bp
  • A to T, chromosome 2 at 27,299,362 bp
  • T to C, chromosome 2 at 32,599,802 bp
  • G to A, chromosome 2 at 35,718,916 bp
  • T to C, chromosome 2 at 52,204,894 bp
  • T to C, chromosome 2 at 85,918,840 bp
  • T to A, chromosome 2 at 91,274,815 bp
  • T to C, chromosome 2 at 112,800,055 bp
  • T to C, chromosome 2 at 125,771,456 bp
  • T to C, chromosome 2 at 164,256,239 bp
  • G to A, chromosome 3 at 59,179,085 bp
  • A to T, chromosome 3 at 124,412,480 bp
  • T to A, chromosome 4 at 47,403,451 bp
  • A to T, chromosome 4 at 89,688,872 bp
  • A to T, chromosome 4 at 121,095,543 bp
  • C to T, chromosome 4 at 140,730,957 bp
  • T to C, chromosome 4 at 144,331,287 bp
  • A to G, chromosome 4 at 149,488,076 bp
  • T to A, chromosome 5 at 90,584,936 bp
  • T to C, chromosome 5 at 135,198,259 bp
  • G to A, chromosome 6 at 127,146,052 bp
  • A to T, chromosome 7 at 96,892,926 bp
  • C to T, chromosome 8 at 71,390,713 bp
  • C to T, chromosome 8 at 105,467,922 bp
  • T to C, chromosome 9 at 58,882,021 bp
  • T to C, chromosome 9 at 113,973,507 bp
  • T to A, chromosome 10 at 20,348,376 bp
  • T to C, chromosome 10 at 79,530,537 bp
  • T to C, chromosome 10 at 111,298,844 bp
  • A to T, chromosome 10 at 128,682,940 bp
  • T to A, chromosome 11 at 32,403,978 bp
  • A to G, chromosome 11 at 59,375,608 bp
  • T to A, chromosome 11 at 59,758,491 bp
  • T to A, chromosome 11 at 65,179,014 bp
  • T to C, chromosome 11 at 102,578,719 bp
  • T to A, chromosome 11 at 115,844,497 bp
  • A to T, chromosome 13 at 55,535,878 bp
  • A to C, chromosome 13 at 67,181,902 bp
  • T to A, chromosome 14 at 50,951,416 bp
  • C to T, chromosome 14 at 50,963,501 bp
  • A to T, chromosome 14 at 103,155,762 bp
  • C to A, chromosome 15 at 101,463,627 bp
  • A to G, chromosome 16 at 58,729,715 bp
  • A to G, chromosome 16 at 81,517,537 bp
  • A to T, chromosome 17 at 8,439,901 bp
  • T to C, chromosome 17 at 20,776,363 bp
  • T to C, chromosome 17 at 25,777,002 bp
  • A to T, chromosome 17 at 85,032,860 bp
  • C to A, chromosome 18 at 22,719,141 bp
  • T to A, chromosome 19 at 8,936,651 bp
  • T to A, chromosome 19 at 23,724,464 bp
  • T to A, chromosome 19 at 40,047,658 bp
  • G to T, chromosome 19 at 40,047,659 bp
  • A to C, chromosome X at 37,607,469 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0097 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038383-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.