Strain Name:
C57BL/6J-MtgxR0104Btlr/Mmmh
Stock Number:
038390-MU
Citation ID:
RRID:MMRRC_038390-MU
Other Names:
R0104 (G1), C57BL/6J-MtgxR0104Btlr
Major Collection:

Gene Information

Mlst8
Name: MTOR associated protein, LST8 homolog (S. cerevisiae)
Synonyms: mLST8, 0610033N12Rik, Gbl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56716
VEGA: 17
Homologene: 6833
Prmt7
Name: protein arginine N-methyltransferase 7
Synonyms: 4933402B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 214572
Homologene: 10382
Kif11
Name: kinesin family member 11
Synonyms: Kifl1, Knsl1, Eg5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16551
VEGA: 19
HGNC: HGNC:6388
Homologene: 3322
Taf2
Name: TATA-box binding protein associated factor 2
Synonyms: CIF150, TAFII150, TAF2B, 4732460C16Rik, 150kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 319944
VEGA: 15
Homologene: 31137
Rif1
Name: replication timing regulatory factor 1
Synonyms: 6530403D07Rik, D2Ertd145e, 5730435J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51869
Homologene: 41231
Rtn1
Name: reticulon 1
Synonyms: Rtn1-a, Rtn1-b, 4930441F12Rik, Nsp, Rtn1-c, 0710005K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104001
Homologene: 49654
Mcpt1
Name: mast cell protease 1
Synonyms: Mcp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 17224
VEGA: 14
Homologene: 137209
Leng8
Name: leukocyte receptor cluster (LRC) member 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232798
Homologene: 13612
Ifrd2
Name: interferon-related developmental regulator 2
Synonyms: SKMc15, 1810034A24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 15983
HGNC: HGNC:5457
Homologene: 21341
Chd6
Name: chromodomain helicase DNA binding protein 6
Synonyms: 6330406J24Rik, 5430439G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71389
Homologene: 32772
Zfp655
Name: zinc finger protein 655
Synonyms: 9030409O18Rik, 2700038I16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72611
Homologene: 12473
Zfc3h1
Name: zinc finger, C3H1-type containing
Synonyms: Ccdc131, Psrc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216345
Homologene: 17017
Itpr3
Name: inositol 1,4,5-triphosphate receptor 3
Synonyms: tf, Itpr-3, Ip3r3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16440
HGNC: HGNC:6182
Homologene: 1675
Pmpcb
Name: peptidase (mitochondrial processing) beta
Synonyms: MPP11, MPPP52, 3110004O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 73078
HGNC: HGNC:9119
Homologene: 3160
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1134Clo, Mdnah5, b2b1565Clo, b2b1537Clo, b2b1154Clo, Dnahc5, b2b3491Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Zfyve9
Name: zinc finger, FYVE domain containing 9
Synonyms: Madhip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230597
HGNC: HGNC:6775
Homologene: 3527
Card19
Name: caspase recruitment domain family, member 19
Synonyms: 1110007C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68480
VEGA: 13
Homologene: 12269
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241516
Homologene: 110349
Slc22a21
Name: solute carrier family 22 (organic cation transporter), member 21
Synonyms: Octn3, Slc22a9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 56517
Homologene: 137336
Arhgap5
Name: Rho GTPase activating protein 5
Synonyms: p190B, p190-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 11855
VEGA: 12
HGNC: HGNC:675
Homologene: 907
Tas2r135
Name: taste receptor, type 2, member 135
Synonyms: mt2r38, Tas2r35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387512
Homologene: 52230
Slc15a2
Name: solute carrier family 15 (H+/peptide transporter), member 2
Synonyms: 8430408C16Rik, Pept2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 57738
Homologene: 56912
Trgv4
Name: T cell receptor gamma, variable 4
Synonyms: Tcrg-V4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21638
Vil1
Name: villin 1
Synonyms: Villin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22349
Homologene: 5169
Dpp10
Name: dipeptidylpeptidase 10
Synonyms: 6430601K09Rik, DPRP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269109
Homologene: 41400
Gm14129
Name: predicted gene 14129
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Homologene: 141190
Kcng1
Name: potassium voltage-gated channel, subfamily G, member 1
Synonyms: OTTMUSG00000016048
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241794
HGNC: HGNC:6248
Homologene: 20515
Gm136
Name: predicted gene 136
Synonyms: LOC214568
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 214568
Homologene: 79759
3100002H09Rik
Name: RIKEN cDNA 3100002H09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Tas2r120
Name: taste receptor, type 2, member 120
Synonyms: mt2r47, Tas2r20, mGR20, T2R20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387348
Homologene: 135705
Ssc5d
Name: scavenger receptor cysteine rich family, 5 domains
Synonyms: A430110N23Rik, s5d-srcrb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269855
Homologene: 77555
Olfr930
Name: olfactory receptor 930
Synonyms: MOR171-46, GA_x6K02T2PVTD-32626123-32627049
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258269
VEGA: 9
Homologene: 138304
Sox30
Name: SRY (sex determining region Y)-box 30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 214105
Homologene: 34027
Ighv2-7
Name: immunoglobulin heavy variable 2-7
Synonyms: Gm16597
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 780793
Olfr113
Name: olfactory receptor 113
Synonyms: GA_x6K02T2PSCP-2034880-2033942, MOR218-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258286
Pcdhb8
Name: protocadherin beta 8
Synonyms: PcdhbH, Pcdhb5C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93879
Homologene: 89038
Nmrk1
Name: nicotinamide riboside kinase 1
Synonyms: BC016495, D630020N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225994
Homologene: 6787
Kcnv2
Name: potassium channel, subfamily V, member 2
Synonyms: KV11.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240595
Homologene: 26423
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 74,418,366 bp
  • A to T, chromosome 1 at 123,367,843 bp
  • T to C, chromosome 2 at 52,110,092 bp
  • A to T, chromosome 2 at 82,978,973 bp
  • T to C, chromosome 2 at 148,931,573 bp
  • A to G, chromosome 2 at 161,039,355 bp
  • A to G, chromosome 2 at 168,269,046 bp
  • G to T, chromosome 4 at 34,746,593 bp
  • C to A, chromosome 4 at 108,718,163 bp
  • C to A, chromosome 4 at 124,610,676 bp
  • C to G, chromosome 5 at 21,746,038 bp
  • T to C, chromosome 5 at 145,244,015 bp
  • A to T, chromosome 6 at 42,406,324 bp
  • T to A, chromosome 6 at 132,657,846 bp
  • A to G, chromosome 7 at 4,143,808 bp
  • T to C, chromosome 7 at 4,936,286 bp
  • T to C, chromosome 8 at 106,237,350 bp
  • A to G, chromosome 9 at 38,930,965 bp
  • T to A, chromosome 9 at 107,587,917 bp
  • G to T, chromosome 10 at 93,028,652 bp
  • T to A, chromosome 10 at 115,415,287 bp
  • A to C, chromosome 11 at 45,981,314 bp
  • A to C, chromosome 11 at 53,951,809 bp
  • A to T, chromosome 12 at 52,516,717 bp
  • A to T, chromosome 12 at 72,308,845 bp
  • A to T, chromosome 12 at 113,807,468 bp
  • C to T, chromosome 13 at 19,185,310 bp
  • G to T, chromosome 13 at 49,208,158 bp
  • T to A, chromosome 14 at 56,019,431 bp
  • A to T, chromosome 15 at 28,453,353 bp
  • T to C, chromosome 15 at 55,038,338 bp
  • T to A, chromosome 16 at 36,774,635 bp
  • T to C, chromosome 17 at 24,476,117 bp
  • C to A, chromosome 17 at 27,095,992 bp
  • T to A, chromosome 17 at 37,574,926 bp
  • A to G, chromosome 18 at 37,355,665 bp
  • T to A, chromosome 19 at 18,641,218 bp
  • T to C, chromosome 19 at 27,323,219 bp
  • T to A, chromosome 19 at 37,413,215 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0104 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038390-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.