Strain Name:
C57BL/6J-MtgxR0132Btlr/Mmmh
Stock Number:
038417-MU
Citation ID:
RRID:MMRRC_038417-MU
Other Names:
R0132 (G1), C57BL/6J-MtgxR0132Btlr
Major Collection:

Gene Information

Kitl
Name: kit ligand
Synonyms: SF, stem cell factor, Steel factor, SLF, Mgf, Sl, Gb, grizzle-belly, Steel, SCF, Kitlg, blz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17311
HGNC: HGNC:6343
Homologene: 692
Chrnb2
Name: cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
Synonyms: [b]2-nAchR, Acrb-2, Acrb2, C030030P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11444
HGNC: HGNC:1962
Homologene: 595
Npl
Name: N-acetylneuraminate pyruvate lyase
Synonyms: 0610033B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74091
Homologene: 12533
Nap1l1
Name: nucleosome assembly protein 1-like 1
Synonyms: D10Ertd68e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 53605
VEGA: 10
HGNC: HGNC:7637
Homologene: 129218
Rprd2
Name: regulation of nuclear pre-mRNA domain containing 2
Synonyms: 6720469I21Rik, 2810036A19Rik, 4930535B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75137
Homologene: 19997
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNA-PKcs, slip, DNAPDcs, XRCC7, DNA-PK, DOXNPH, dxnph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Ascc3
Name: activating signal cointegrator 1 complex subunit 3
Synonyms: ASC1p200, B630009I04Rik, Helic1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77987
VEGA: 10
Homologene: 4973
Srrm1
Name: serine/arginine repetitive matrix 1
Synonyms: SRm160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 51796
Zmym2
Name: zinc finger, MYM-type 2
Synonyms: SCLL, RAMP, MYM, FIM, Zfp198
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 76007
VEGA: 14
Homologene: 12631
Mdc1
Name: mediator of DNA damage checkpoint 1
Synonyms: NFBD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240087
Homologene: 67092
R3hdm2
Name: R3H domain containing 2
Synonyms: 1300003K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71750
Homologene: 8954
Cttnbp2nl
Name: CTTNBP2 N-terminal like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80281
Homologene: 36371
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: D130015N03Rik, 2810449H11Rik, tbl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Chd8
Name: chromodomain helicase DNA binding protein 8
Synonyms: 5830451P18Rik, Duplin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67772
Homologene: 72405
Htr1f
Name: 5-hydroxytryptamine (serotonin) receptor 1F
Synonyms: Htr1eb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 15557
VEGA: 16
HGNC: HGNC:5292
Homologene: 37361
Kcnj9
Name: potassium inwardly-rectifying channel, subfamily J, member 9
Synonyms: Kir3.3, Girk3, 1700085N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16524
HGNC: HGNC:6270
Homologene: 37989
Adamtsl1
Name: ADAMTS-like 1
Synonyms: punctin-1, 6720426B09Rik, 5930437A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 77739
Homologene: 64642
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: per, Pcn, Plc, perlecan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Anxa5
Name: annexin A5
Synonyms: Anx5, annexin V
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11747
HGNC: HGNC:543
Homologene: 20312
Hp1bp3
Name: heterochromatin protein 1, binding protein 3
Synonyms: Hp1bp74
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15441
Homologene: 7774
Dazap1
Name: DAZ associated protein 1
Synonyms: 2410042M16Rik, mPrrp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70248
HGNC: HGNC:2683
Homologene: 134440
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269700
Homologene: 28297
Atp2b2
Name: ATPase, Ca++ transporting, plasma membrane 2
Synonyms: PMCA2, wms, D6Abb2e, jog, Tmy, Gena300
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11941
HGNC: HGNC:815
Homologene: 56150
Pkp2
Name: plakophilin 2
Synonyms: 1200012P04Rik, 1200008D14Rik, Pkp2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67451
HGNC: HGNC:9024
Homologene: 3364
Slc35d1
Name: solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
Synonyms: UGTREL7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242585
Homologene: 22870
Mocos
Name: molybdenum cofactor sulfurase
Synonyms: 1110018O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68591
VEGA: 18
Homologene: 9931
Lrrc74b
Name: leucine rich repeat containing 74B
Synonyms: 4930451C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74685
Homologene: 25894
Tmem116
Name: transmembrane protein 116
Synonyms: 4930513P12Rik, 4930406A18Rik, C030022K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 77462
Homologene: 12676
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Myh8
Name: myosin, heavy polypeptide 8, skeletal muscle, perinatal
Synonyms: MyHC-pn, Myhs-p, Myhsp, 4832426G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17885
HGNC: HGNC:7578
Homologene: 68256
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip-rs6, Naip2, Birc1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
9530053A07Rik
Name: RIKEN cDNA 9530053A07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319482
Homologene: 130055
Abcc12
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Synonyms: MRP9, 4930467B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244562
Homologene: 57211
Vmn2r102
Name: vomeronasal 2, receptor 102
Synonyms: EG224572
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224572
Homologene: 115024
Stac3
Name: SH3 and cysteine rich domain 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237611
Homologene: 17039
Ptprt
Name: protein tyrosine phosphatase, receptor type, T
Synonyms: RPTPrho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19281
HGNC: HGNC:9682
Homologene: 56924
Ptprn2
Name: protein tyrosine phosphatase, receptor type, N polypeptide 2
Synonyms: PTP-NP, IA-2 beta, phogrin, IA-2beta, 4930425H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19276
HGNC: HGNC:9677
Homologene: 2134
Olfr372
Name: olfactory receptor 372
Synonyms: GA_x6K02T2NUPS-191522-192466, MOR282-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 404315
Homologene: 17287
Col16a1
Name: collagen, type XVI, alpha 1
Synonyms: [a]1 (XVI) collagen, 2700007F12Rik, A530052M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 107581
HGNC: HGNC:2193
Homologene: 1397
Cfhr4
Name: complement factor H-related 4
Synonyms: Gm4788
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 214403
Ppox
Name: protoporphyrinogen oxidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19044
HGNC: HGNC:9280
Homologene: 262
Olfr417
Name: olfactory receptor 417
Synonyms: GA_x6K02T2P20D-20787051-20786119, MOR267-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258238
Homologene: 17358
Psd4
Name: pleckstrin and Sec7 domain containing 4
Synonyms: SEC7 homolog, EFA6B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215632
Homologene: 8261
Lpcat4
Name: lysophosphatidylcholine acyltransferase 4
Synonyms: Aytl3, Agpat7, LPEAT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99010
Homologene: 27544
Bpifa6
Name: BPI fold containing family A, member 6
Synonyms: Gm5840
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545477
Homologene: 129594
Gm16069
Name: predicted gene 16069
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 102636781
Iqcc
Name: IQ motif containing C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230767
Homologene: 49526
Ugt2a1
Name: UDP glucuronosyltransferase 2 family, polypeptide A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 94215
Homologene: 136808
Slc29a4
Name: solute carrier family 29 (nucleoside transporters), member 4
Synonyms: ENT4, mPMAT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243328
Homologene: 71345
Fam187b
Name: family with sequence similarity 187, member B
Synonyms: 1700020B09Rik, Tmem162
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76415
Homologene: 138431
Hinfp
Name: histone H4 transcription factor
Synonyms: DKFZp434F162, Mizf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102423
VEGA: 9
Homologene: 9174
Tspyl1
Name: testis-specific protein, Y-encoded-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22110
Homologene: 22522
Ntn4
Name: netrin 4
Synonyms: beta-netrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 57764
Homologene: 10934
Tmcc3
Name: transmembrane and coiled coil domains 3
Synonyms: C630016B22Rik, LOC380656, A230066D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 319880
Homologene: 10792
Slc25a35
Name: solute carrier family 25, member 35
Synonyms: 1810012H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71998
Homologene: 6343
Nin
Name: ninein
Synonyms: 3110068G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18080
Homologene: 40632
Tmem260
Name: transmembrane protein 260
Synonyms: 6720456H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218989
Homologene: 49506
Siah3
Name: siah E3 ubiquitin protein ligase family member 3
Synonyms: LOC380918
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 380918
VEGA: 14
Homologene: 54375
Olfr177
Name: olfactory receptor 177
Synonyms: GA_x54KRFPKG5P-55091371-55090442, MOR184-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258998
Homologene: 121500
Vmn2r90
Name: vomeronasal 2, receptor 90
Synonyms: EG626942
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 626942
Rab26
Name: RAB26, member RAS oncogene family
Synonyms: A830020M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 328778
Homologene: 25655
H2-T24
Name: histocompatibility 2, T region locus 24
Synonyms: H-2T24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15042
Homologene: 69019
Slc14a2
Name: solute carrier family 14 (urea transporter), member 2
Synonyms: UT-A3, UT-A5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 27411
VEGA: 18
Homologene: 5183
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 139,754,271 bp
  • T to A, chromosome 1 at 153,509,118 bp
  • C to A, chromosome 1 at 171,279,275 bp
  • T to C, chromosome 1 at 172,326,198 bp
  • T to C, chromosome 1 at 174,369,586 bp
  • C to A, chromosome 2 at 24,405,351 bp
  • A to G, chromosome 2 at 112,246,748 bp
  • T to A, chromosome 2 at 153,982,931 bp
  • C to T, chromosome 2 at 162,278,110 bp
  • G to A, chromosome 3 at 36,450,672 bp
  • T to C, chromosome 3 at 89,180,925 bp
  • T to C, chromosome 3 at 89,764,406 bp
  • T to C, chromosome 3 at 95,774,361 bp
  • T to G, chromosome 3 at 105,005,857 bp
  • T to A, chromosome 4 at 86,342,723 bp
  • C to T, chromosome 4 at 103,208,181 bp
  • T to G, chromosome 4 at 129,616,599 bp
  • T to A, chromosome 4 at 130,067,096 bp
  • G to A, chromosome 4 at 135,340,573 bp
  • T to C, chromosome 4 at 137,551,887 bp
  • C to T, chromosome 4 at 138,237,209 bp
  • T to A, chromosome 5 at 87,474,861 bp
  • A to G, chromosome 5 at 121,333,024 bp
  • A to G, chromosome 5 at 121,493,782 bp
  • A to G, chromosome 5 at 142,705,530 bp
  • G to A, chromosome 6 at 113,793,782 bp
  • A to G, chromosome 7 at 28,137,615 bp
  • T to A, chromosome 7 at 30,989,120 bp
  • C to T, chromosome 8 at 72,058,400 bp
  • A to G, chromosome 8 at 86,531,568 bp
  • A to G, chromosome 9 at 44,299,763 bp
  • A to C, chromosome 9 at 66,480,910 bp
  • A to G, chromosome 10 at 34,283,089 bp
  • T to G, chromosome 10 at 50,735,329 bp
  • T to G, chromosome 10 at 80,278,226 bp
  • T to A, chromosome 10 at 93,644,707 bp
  • T to C, chromosome 10 at 94,545,575 bp
  • C to T, chromosome 10 at 100,087,364 bp
  • T to C, chromosome 10 at 111,485,509 bp
  • T to A, chromosome 10 at 127,498,453 bp
  • A to T, chromosome 10 at 127,503,650 bp
  • A to G, chromosome 11 at 67,292,188 bp
  • A to G, chromosome 11 at 68,971,960 bp
  • A to G, chromosome 11 at 119,430,361 bp
  • T to G, chromosome 12 at 70,051,141 bp
  • T to G, chromosome 12 at 116,722,091 bp
  • A to G, chromosome 13 at 100,183,788 bp
  • T to A, chromosome 14 at 48,483,322 bp
  • A to G, chromosome 14 at 52,205,326 bp
  • A to G, chromosome 14 at 56,943,258 bp
  • G to A, chromosome 14 at 75,456,134 bp
  • T to C, chromosome 16 at 15,713,653 bp
  • T to C, chromosome 16 at 16,240,713 bp
  • T to C, chromosome 16 at 17,553,152 bp
  • C to A, chromosome 16 at 58,872,906 bp
  • A to G, chromosome 16 at 64,926,728 bp
  • T to A, chromosome 17 at 17,712,249 bp
  • A to C, chromosome 17 at 19,678,763 bp
  • C to T, chromosome 17 at 24,530,785 bp
  • T to A, chromosome 17 at 35,852,581 bp
  • T to A, chromosome 17 at 36,014,986 bp
  • T to G, chromosome 18 at 24,679,762 bp
  • T to A, chromosome 18 at 78,192,123 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
(Deceased) Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0132 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038417-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.