Strain Name:
C57BL/6J-MtgxR0140Btlr/Mmmh
Stock Number:
038425-MU
Citation ID:
RRID:MMRRC_038425-MU
Other Names:
R0140 (G1), C57BL/6J-MtgxR0140Btlr
Major Collection:

Gene Information

Cdk4
Name: cyclin-dependent kinase 4
Synonyms: Crk3, p34PSK-J3/cdk4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 12567
HGNC: HGNC:1773
Homologene: 55429
Ntrk1
Name: neurotrophic tyrosine kinase, receptor, type 1
Synonyms: Tkr, TrkA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18211
HGNC: HGNC:8031
Homologene: 1898
Sipa1l1
Name: signal-induced proliferation-associated 1 like 1
Synonyms: 4931426N11Rik, Spar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217692
VEGA: 12
Homologene: 9189
Fubp3
Name: far upstream element (FUSE) binding protein 3
Synonyms: A330051M14Rik, Marta2, FBP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 320267
HGNC: HGNC:4005
Homologene: 45954
Stx1a
Name: syntaxin 1A (brain)
Synonyms: HPC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20907
Homologene: 37941
Slk
Name: STE20-like kinase
Synonyms: SLK, mSLK, Etk4, 9A2, Stk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 20874
Homologene: 22515
Wwox
Name: WW domain-containing oxidoreductase
Synonyms: 5330426P09Rik, 9030416C10Rik, WOX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 80707
Homologene: 56334
Racgap1
Name: Rac GTPase-activating protein 1
Synonyms: MgcRacGAP, gtl11, Band25, GTPase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 26934
HGNC: HGNC:9804
Homologene: 8077
Tle1
Name: transducin-like enhancer of split 1
Synonyms: Estm14, Tle4l, Grg1, C230057C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 21885
Homologene: 21058
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, D330028K02Rik, Calmbp1, Aspm, MCPH5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12316
Homologene: 7650
Utp6
Name: UTP6 small subunit processome component
Synonyms: HCA66, 4732497O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216987
Homologene: 41265
Clcn7
Name: chloride channel, voltage-sensitive 7
Synonyms: ClC-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 26373
HGNC: HGNC:2025
Homologene: 56546
Camsap2
Name: calmodulin regulated spectrin-associated protein family, member 2
Synonyms: 4930541M15Rik, Camsap1l1, 1600013L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 67886
Homologene: 18927
Tbc1d15
Name: TBC1 domain family, member 15
Synonyms: 4432405K22Rik, Ly6dl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66687
VEGA: 10
Homologene: 11249
Ubqln1
Name: ubiquilin 1
Synonyms: 1810030E05Rik, DA41, Dsk2, D13Ertd372e, XDRP1, Plic-1, 1110046H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 56085
VEGA: 13
Homologene: 137258
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: 8430405D05Rik, C130099L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 195018
Homologene: 9027
Pggt1b
Name: protein geranylgeranyltransferase type I, beta subunit
Synonyms: GGT1, BGG1, 2010207C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225467
VEGA: 18
HGNC: HGNC:8895
Homologene: 3685
Lepr
Name: leptin receptor
Synonyms: Leprb, LEPROT, Modb1, OB-RGRP, leptin receptor gene-related protein, obl, obese-like, Obr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16847
HGNC: HGNC:6554
Homologene: 1731
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: Doc4, ELM2, l7Rn3, Odz4, Ten-m4, l(7)-3Rn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 23966
Homologene: 8034
Crebbp
Name: CREB binding protein
Synonyms: KAT3A, CBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12914
HGNC: HGNC:2348
Homologene: 68393
Nrip3
Name: nuclear receptor interacting protein 3
Synonyms: A330103B05Rik, ICRFP703N2430Q5.2, D7H11orf14, ICRFP703B1614Q5.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 78593
HGNC: HGNC:1167
Homologene: 10764
Rnf103
Name: ring finger protein 103
Synonyms: Zfp103, kf-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 22644
Homologene: 4146
Adgrf3
Name: adhesion G protein-coupled receptor F3
Synonyms: Gpr113, LOC381628, PGR23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381628
Homologene: 17826
Sept2
Name: septin 2
Synonyms: Nedd5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18000
HGNC: HGNC:7729
Homologene: 3243
Vav2
Name: vav 2 oncogene
Synonyms: 2810040F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22325
Homologene: 2530
Setd6
Name: SET domain containing 6
Synonyms: 0610039J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 66083
Homologene: 38743
Nolc1
Name: nucleolar and coiled-body phosphoprotein 1
Synonyms: NOPP140, 3230402K17Rik, P130
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 70769
VEGA: 19
Prcp
Name: prolylcarboxypeptidase (angiotensinase C)
Synonyms: 2510048K03Rik, 2610104A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72461
HGNC: HGNC:9344
Homologene: 55867
Blnk
Name: B cell linker
Synonyms: Bca, Ly-57, SLP-65, BCA, BASH, BLNK, Ly57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 17060
Homologene: 32038
Atp4a
Name: ATPase, H+/K+ exchanging, gastric, alpha polypeptide
Synonyms: H+K+-transporting alpha 1, H+/K+-ATPase alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11944
HGNC: HGNC:819
Homologene: 68081
Myof
Name: myoferlin
Synonyms: E030042N20Rik, Fer1l3, 2310051D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Il12rb1
Name: interleukin 12 receptor, beta 1
Synonyms: CD212, IL-12R[b]
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16161
HGNC: HGNC:5971
Homologene: 4042
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225997
VEGA: 19
Homologene: 9767
Zfp646
Name: zinc finger protein 646
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233905
Homologene: 8802
Celsr2
Name: cadherin, EGF LAG seven-pass G-type receptor 2
Synonyms: Adgrc2, mfmi1, EGFL2, flamingo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 53883
HGNC: HGNC:3231
Homologene: 1078
Slc16a12
Name: solute carrier family 16 (monocarboxylic acid transporters), member 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240638
Homologene: 130007
Cdhr3
Name: cadherin-related family member 3
Synonyms: 1110049B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68764
VEGA: 12
Homologene: 45146
Phkg1
Name: phosphorylase kinase gamma 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18682
HGNC: HGNC:8930
Homologene: 68508
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 245026
Homologene: 18260
Pxdn
Name: peroxidasin
Synonyms: 2310075M15Rik, VPO1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 69675
Homologene: 33907
Fam227b
Name: family with sequence similarity 227, member B
Synonyms: 4930525F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75823
Homologene: 27384
Paox
Name: polyamine oxidase (exo-N4-amino)
Synonyms: Pao, 2410012F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 212503
Homologene: 72096
CAAA01180111.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Cps1
Name: carbamoyl-phosphate synthetase 1
Synonyms: 4732433M03Rik, CPS, D1Ucla3, CPSase I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227231
HGNC: HGNC:2323
Homologene: 68208
Olfr801
Name: olfactory receptor 801
Synonyms: GA_x6K02T2PULF-11349138-11348182, MOR110-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258282
Homologene: 138306
Pnmal1
Name: PNMA-like 1
Synonyms: 4930488B01Rik, 0710005I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 71691
Homologene: 10073
Abca2
Name: ATP-binding cassette, sub-family A (ABC1), member 2
Synonyms: D2H0S1474E, Abc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11305
HGNC: HGNC:32
Homologene: 55590
Arhgef26
Name: Rho guanine nucleotide exchange factor (GEF) 26
Synonyms: 8430436L14Rik, 4631416L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 622434
Homologene: 9204
Ccdc40
Name: coiled-coil domain containing 40
Synonyms: B930008I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 207607
Homologene: 27890
Npbwr1
Name: neuropeptides B/W receptor 1
Synonyms: Gpr7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226304
HGNC: HGNC:4522
Homologene: 21096
Tmem9
Name: transmembrane protein 9
Synonyms: 1500015G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 66241
Homologene: 9515
Arhgap15
Name: Rho GTPase activating protein 15
Synonyms: 5830480G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 76117
Homologene: 41271
Olfr1115
Name: olfactory receptor 1115
Synonyms: MOR273-4P, GA_x6K02T2Q125-48736906-48737886, Olfr1530-ps1, MOR264-20, MOR273-4P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258294
Homologene: 27114
Olfr1261
Name: olfactory receptor 1261
Synonyms: GA_x6K02T2Q125-51425355-51426275, MOR234-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258466
Homologene: 138310
Hrnr
Name: hornerin
Synonyms: S100a18, 1110033K19Rik, A530063N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68723
Homologene: 138092
Phtf1
Name: putative homeodomain transcription factor 1
Synonyms: Phft
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18685
HGNC: HGNC:8939
Homologene: 4817
Dennd2d
Name: DENN/MADD domain containing 2D
Synonyms: 2010308M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72121
Homologene: 11776
Tmem268
Name: transmembrane protein 268
Synonyms: 6330416G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230279
Homologene: 17005
Urad
Name: ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase
Synonyms: Prhoxnb, EG231903
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231903
Homologene: 82563
Vmn2r55
Name: vomeronasal 2, receptor 55
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100042499
Homologene: 104040
Olfr628
Name: olfactory receptor 628
Synonyms: MOR22-1, MOR22-4P, MOR22-4P, Olfr1526-ps1, GA_x6K02T2PBJ9-6457667-6458617
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259159
Homologene: 8420
Tufm
Name: Tu translation elongation factor, mitochondrial
Synonyms: C76308, EF-TuMT, 2300002G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233870
Homologene: 2490
Calr3
Name: calreticulin 3
Synonyms: calsperin, Crt2, 1700031L01Rik, 6330586I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 73316
Homologene: 57091
Fbxw24
Name: F-box and WD-40 domain protein 24
Synonyms: Gm5162
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382106
Homologene: 110776
Ccdc69
Name: coiled-coil domain containing 69
Synonyms: 2210021E03Rik, D11Ertd461e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 52570
Homologene: 77613
Olfr222
Name: olfactory receptor 222
Synonyms: GA_x6K02SYYHDF-1415-2371, MOR256-45P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 257962
Homologene: 71979
Tmc6
Name: transmembrane channel-like gene family 6
Synonyms: EVER1, D11Ertd204e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217353
Homologene: 5258
9330161L09Rik
Name: RIKEN cDNA 9330161L09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
Nfil3
Name: nuclear factor, interleukin 3, regulated
Synonyms: E4BP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18030
HGNC: HGNC:7787
Homologene: 3928
AY358078
Name: cDNA sequence AY358078
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 278676
Homologene: 115686
Gm19684
Name: predicted gene, 19684
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
Pcdhb9
Name: protocadherin beta 9
Synonyms: Pcdhb4C, PcdhbI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93880
Homologene: 87124
Pnliprp2
Name: pancreatic lipase-related protein 2
Synonyms: PLRP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18947
VEGA: 19
HGNC: HGNC:9157
Homologene: 3936
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 5,916,621 bp
  • T to G, chromosome 1 at 67,180,116 bp
  • A to G, chromosome 1 at 93,501,639 bp
  • A to G, chromosome 1 at 136,034,162 bp
  • A to T, chromosome 1 at 136,280,382 bp
  • C to T, chromosome 1 at 139,480,641 bp
  • T to G, chromosome 2 at 25,438,085 bp
  • C to T, chromosome 2 at 27,273,676 bp
  • T to C, chromosome 2 at 31,608,184 bp
  • C to A, chromosome 2 at 44,322,767 bp
  • A to G, chromosome 2 at 87,252,625 bp
  • T to A, chromosome 2 at 89,994,119 bp
  • T to C, chromosome 2 at 126,124,603 bp
  • C to G, chromosome 3 at 62,448,245 bp
  • A to C, chromosome 3 at 87,778,568 bp
  • C to T, chromosome 3 at 93,331,493 bp
  • A to T, chromosome 3 at 103,987,560 bp
  • G to A, chromosome 3 at 106,492,483 bp
  • C to T, chromosome 3 at 108,397,933 bp
  • G to A, chromosome 4 at 63,577,859 bp
  • G to A, chromosome 4 at 72,120,185 bp
  • A to T, chromosome 4 at 101,768,067 bp
  • T to C, chromosome 5 at 30,196,381 bp
  • T to A, chromosome 5 at 129,864,608 bp
  • T to C, chromosome 5 at 135,045,585 bp
  • T to G, chromosome 5 at 147,322,331 bp
  • T to A, chromosome 6 at 71,509,331 bp
  • G to T, chromosome 7 at 12,668,177 bp
  • A to G, chromosome 7 at 16,960,222 bp
  • C to G, chromosome 7 at 30,720,101 bp
  • A to G, chromosome 7 at 92,928,611 bp
  • T to C, chromosome 7 at 96,896,052 bp
  • A to G, chromosome 7 at 103,732,142 bp
  • T to C, chromosome 7 at 109,761,815 bp
  • C to T, chromosome 7 at 126,489,831 bp
  • T to A, chromosome 7 at 127,883,506 bp
  • A to T, chromosome 7 at 140,134,058 bp
  • T to C, chromosome 8 at 70,819,771 bp
  • C to T, chromosome 8 at 72,434,888 bp
  • T to A, chromosome 8 at 95,716,109 bp
  • T to G, chromosome 8 at 114,706,287 bp
  • A to G, chromosome 9 at 105,702,275 bp
  • G to T, chromosome 9 at 109,605,414 bp
  • T to C, chromosome 9 at 124,295,159 bp
  • T to A, chromosome 10 at 115,220,219 bp
  • T to C, chromosome 10 at 127,064,345 bp
  • G to T, chromosome 10 at 129,669,688 bp
  • C to A, chromosome 11 at 55,050,499 bp
  • A to G, chromosome 11 at 59,570,978 bp
  • G to A, chromosome 11 at 72,899,551 bp
  • A to G, chromosome 11 at 79,956,725 bp
  • A to G, chromosome 11 at 117,766,251 bp
  • G to A, chromosome 11 at 119,264,299 bp
  • A to G, chromosome 12 at 29,982,754 bp
  • T to G, chromosome 12 at 33,080,413 bp
  • G to A, chromosome 12 at 82,396,200 bp
  • T to C, chromosome 12 at 103,407,328 bp
  • G to A, chromosome 13 at 52,967,645 bp
  • A to G, chromosome 13 at 58,193,289 bp
  • T to A, chromosome 14 at 51,825,942 bp
  • A to T, chromosome 15 at 99,623,651 bp
  • G to T, chromosome 16 at 4,117,499 bp
  • A to G, chromosome 17 at 25,153,754 bp
  • T to C, chromosome 17 at 36,127,427 bp
  • T to A, chromosome 18 at 37,402,961 bp
  • A to G, chromosome 18 at 46,258,083 bp
  • A to G, chromosome 19 at 18,819,194 bp
  • G to T, chromosome 19 at 34,672,704 bp
  • A to T, chromosome 19 at 37,951,556 bp
  • A to T, chromosome 19 at 40,940,224 bp
  • G to A, chromosome 19 at 46,081,378 bp
  • G to A, chromosome 19 at 47,622,335 bp
  • A to T, chromosome 19 at 58,766,363 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0140 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038425-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.