Strain Name:
C57BL/6J-MtgxR0141Btlr/Mmmh
Stock Number:
038426-MU
Citation ID:
RRID:MMRRC_038426-MU
Other Names:
R0141 (G1), C57BL/6J-MtgxR0141Btlr
Major Collection:

Gene Information

Nfat5
Name: nuclear factor of activated T cells 5
Synonyms: OREBP, nfatz, TonEBP, B130038B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 54446
HGNC: HGNC:7774
Homologene: 4811
Hps5
Name: HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
Synonyms: ru-2, ruby eye 2, ru2, Hermansky-Pudlak syndrome 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 246694
Homologene: 35333
Fn1
Name: fibronectin 1
Synonyms: Fn, Fn-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14268
HGNC: HGNC:3778
Homologene: 1533
Fam131a
Name: family with sequence similarity 131, member A
Synonyms: 2900046G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 78408
Homologene: 82234
Slc17a6
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
Synonyms: VGLUT2, 2900073D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 140919
Homologene: 121617
Lhx9
Name: LIM homeobox protein 9
Synonyms: 3110009O07Rik, LH2B, Lhx9 alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16876
Homologene: 7816
Cpt1c
Name: carnitine palmitoyltransferase 1c
Synonyms: CPT I-C, 9630004I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78070
Homologene: 17561
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F32S1, rjs, jdf2, D15F32S1h, D7H15F37S1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Tsen2
Name: tRNA splicing endonuclease subunit 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381802
Homologene: 41622
Ckap2l
Name: cytoskeleton associated protein 2-like
Synonyms: 2610318C08Rik, Radmis, 2010016H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70466
Homologene: 51866
Osbp
Name: oxysterol binding protein
Synonyms: 1110018F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 76303
VEGA: 19
HGNC: HGNC:8503
Homologene: 97668
Def8
Name: differentially expressed in FDCP 8
Synonyms: D8Ertd713e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23854
Homologene: 14279
Pnpla6
Name: patatin-like phospholipase domain containing 6
Synonyms: Swiss-cheese, Nte, MSws
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 50767
Homologene: 21333
Gtsf1l
Name: gametocyte specific factor 1-like
Synonyms: 2410116G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68236
Homologene: 32667
Tsc22d2
Name: TSC22 domain family, member 2
Synonyms: 5530402M19Rik, 1810043J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72033
Homologene: 8860
Rnf6
Name: ring finger protein (C3H2C3 type) 6
Synonyms: 1200013I08Rik, 5730419H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74132
Homologene: 14036
Ice1
Name: interactor of little elongation complex ELL subunit 1
Synonyms: BC018507
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218333
VEGA: 13
Homologene: 18902
Ebf1
Name: early B cell factor 1
Synonyms: O/E-1, Olf-1, Olf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13591
HGNC: HGNC:3126
Homologene: 7297
Scn1a
Name: sodium channel, voltage-gated, type I, alpha
Synonyms: Nav1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20265
Homologene: 21375
Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Synonyms: Mlr, mineralocorticoid receptor, aldosterone receptor, MR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 110784
HGNC: HGNC:7979
Homologene: 121495
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: diminished cone electroretinogram, D12Ertd777e, dice, syne-2, nesprin-2, 6820443O06Rik, Cpfl8, Nesp2g
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Pkdrej
Name: polycystin (PKD) family receptor for egg jelly
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18766
VEGA: 15
HGNC: HGNC:9015
Homologene: 4427
Col27a1
Name: collagen, type XXVII, alpha 1
Synonyms: 5730512J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 373864
Homologene: 69400
Fer1l6
Name: fer-1-like 6 (C. elegans)
Synonyms: EG631797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 631797
Homologene: 53396
Galnt18
Name: polypeptide N-acetylgalactosaminyltransferase 18
Synonyms: Galntl4, 2900011G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233733
Homologene: 18347
Rb1cc1
Name: RB1-inducible coiled-coil 1
Synonyms: Fip200, 5930404L04Rik, 2900055E04Rik, LaXp180, Cc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12421
Homologene: 7659
Scn2a
Name: sodium channel, voltage-gated, type II, alpha
Synonyms: Nav1.2, Scn2a1, A230052E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 110876
Homologene: 75001
4931408C20Rik
Name: RIKEN cDNA 4931408C20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210940
Homologene: 86827
Gm884
Name: predicted gene 884
Synonyms: LOC380730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380730
Homologene: 134511
Adamts9
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
Synonyms: Mhdaund4, 8430403M15Rik, E030027K14Rik, 1810011L16Rik, Gsfund3, UND4, Mhdaund3, UND3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 101401
Homologene: 18821
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: 2310047C17Rik, DY6, 1110004P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Igsf10
Name: immunoglobulin superfamily, member 10
Synonyms: CMF608, 6530405F15Rik, Adlican2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242050
Homologene: 18712
Acot12
Name: acyl-CoA thioesterase 12
Synonyms: 1300004O04Rik, Cach, 4930449F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 74156
Homologene: 12540
Ugt2b37
Name: UDP glucuronosyltransferase 2 family, polypeptide B37
Synonyms: 0610033E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 112417
Homologene: 137225
Olfr1283
Name: olfactory receptor 1283
Synonyms: GA_x6K02T2Q125-72420217-72421134, MOR248-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228443
Homologene: 133657
Arfgef3
Name: ARFGEF family member 3
Synonyms: BIG3, B930094H20Rik, D10Bwg1379e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215821
VEGA: 10
Homologene: 41366
Rtl1
Name: retrotransposon Gaglike 1
Synonyms: Mor1, Mart1, Mar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 353326
VEGA: 12
Homologene: 120261
Vmn2r58
Name: vomeronasal 2, receptor 58
Synonyms: EG628422
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628422
Olfr152
Name: olfactory receptor 152
Synonyms: MOR181-1, GA_x6K02T2Q125-49283184-49284128, V1, Olfr4-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258640
HGNC: HGNC:8347
Homologene: 4835
Ccndbp1
Name: cyclin D-type binding-protein 1
Synonyms: GCIP, DIP1, Maid, stage specific embryonic cDNA-8, SSEC-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17151
HGNC: HGNC:1587
Homologene: 7826
Pxmp4
Name: peroxisomal membrane protein 4
Synonyms: 3010018P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 59038
Homologene: 5237
Rwdd3
Name: RWD domain containing 3
Synonyms: RSUME, 2510027J23Rik, 3110037C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66568
Homologene: 22899
Pou3f2
Name: POU domain, class 3, transcription factor 2
Synonyms: Otf7, Brn2, 9430075J19Rik, Brn-2, A230098E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18992
HGNC: HGNC:9215
Homologene: 4095
Pramel22
Name: PRAME like 22
Synonyms: Gm13088
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 277668
Homologene: 129883
Cyp3a57
Name: cytochrome P450, family 3, subfamily a, polypeptide 57
Synonyms: EG622127
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 622127
Homologene: 135775
Vmn1r68
Name: vomeronasal 1 receptor 68
Synonyms: Gm6898
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628580
Homologene: 120153
Fbxo17
Name: F-box protein 17
Synonyms: Fbx17, Fbg4, FBXO26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 50760
Homologene: 17523
Olfr487
Name: olfactory receptor 487
Synonyms: MOR204-29P, Olfr1538-ps1, MOR204-31P, MOR204-31P, GA_x6K02T2PBJ9-10541702-10540758
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258042
Homologene: 110483
Olfr495
Name: olfactory receptor 495
Synonyms: MOR204-37, GA_x6K02T2PBJ9-10725148-10726140
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258361
Homologene: 133600
Hapln4
Name: hyaluronan and proteoglycan link protein 4
Synonyms: Bral2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330790
Homologene: 11304
AW551984
Name: expressed sequence AW551984
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244810
Loxl1
Name: lysyl oxidase-like 1
Synonyms: LOXL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16949
VEGA: 9
HGNC: HGNC:6665
Homologene: 4074
Tex14
Name: testis expressed gene 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 83560
Homologene: 12838
Plek2
Name: pleckstrin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 27260
Homologene: 8447
Serpina3b
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3B
Synonyms: 6A1, A030003A19Rik, antitrypsin, alpha-1 antiproteinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 271047
HGNC: HGNC:16
Homologene: 120222
Olfr749
Name: olfactory receptor 749
Synonyms: GA_x6K02T2PMLR-6484046-6483105, MOR106-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56858
Homologene: 10652
Tfb1m
Name: transcription factor B1, mitochondrial
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224481
VEGA: 17
Homologene: 9343
Esp6
Name: exocrine gland secreted peptide 6
Synonyms: Esp5, Gm5494
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 433107
VEGA: 17
Zfp959
Name: zinc finger protein 959
Synonyms: BC011426
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224893
Homologene: 138295
Sh3rf2
Name: SH3 domain containing ring finger 2
Synonyms: RNF158, 9130023G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 269016
Homologene: 17618
Dmrt2
Name: doublesex and mab-3 related transcription factor 2
Synonyms: Terra
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226049
VEGA: 19
HGNC: HGNC:2935
Homologene: 17111
Tll2
Name: tolloid-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 24087
VEGA: 19
Homologene: 56545
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 6,265,567 bp
  • A to T, chromosome 1 at 26,683,782 bp
  • A to T, chromosome 1 at 71,586,292 bp
  • A to G, chromosome 1 at 138,840,006 bp
  • T to A, chromosome 2 at 65,711,816 bp
  • C to A, chromosome 2 at 66,289,062 bp
  • C to G, chromosome 2 at 87,782,705 bp
  • T to A, chromosome 2 at 111,369,490 bp
  • T to A, chromosome 2 at 121,012,422 bp
  • A to G, chromosome 2 at 129,291,019 bp
  • A to G, chromosome 2 at 154,592,295 bp
  • T to C, chromosome 2 at 163,087,326 bp
  • A to T, chromosome 3 at 58,417,156 bp
  • A to G, chromosome 3 at 59,330,832 bp
  • C to T, chromosome 3 at 121,156,529 bp
  • T to C, chromosome 4 at 22,487,210 bp
  • A to T, chromosome 4 at 63,265,633 bp
  • T to C, chromosome 4 at 143,654,568 bp
  • A to T, chromosome 5 at 14,791,922 bp
  • G to A, chromosome 5 at 87,240,983 bp
  • A to G, chromosome 5 at 145,362,102 bp
  • A to T, chromosome 5 at 146,211,835 bp
  • T to C, chromosome 6 at 92,943,085 bp
  • A to G, chromosome 6 at 115,568,829 bp
  • T to C, chromosome 7 at 10,527,325 bp
  • A to G, chromosome 7 at 28,733,491 bp
  • G to A, chromosome 7 at 41,861,885 bp
  • A to G, chromosome 7 at 44,966,671 bp
  • A to G, chromosome 7 at 46,789,181 bp
  • G to A, chromosome 7 at 51,669,067 bp
  • A to G, chromosome 7 at 56,121,561 bp
  • A to C, chromosome 7 at 108,212,003 bp
  • A to T, chromosome 7 at 108,395,368 bp
  • A to T, chromosome 7 at 111,599,031 bp
  • G to T, chromosome 8 at 3,532,117 bp
  • T to C, chromosome 8 at 70,088,280 bp
  • T to A, chromosome 8 at 76,908,408 bp
  • C to T, chromosome 8 at 107,339,075 bp
  • G to A, chromosome 8 at 123,456,495 bp
  • A to G, chromosome 9 at 39,590,644 bp
  • T to A, chromosome 9 at 58,312,132 bp
  • C to A, chromosome 10 at 18,597,407 bp
  • G to A, chromosome 10 at 39,092,278 bp
  • T to C, chromosome 11 at 44,908,000 bp
  • T to G, chromosome 11 at 87,493,031 bp
  • A to C, chromosome 11 at 103,613,686 bp
  • T to G, chromosome 12 at 75,941,298 bp
  • A to G, chromosome 12 at 78,894,504 bp
  • A to T, chromosome 12 at 104,130,771 bp
  • A to G, chromosome 12 at 109,592,948 bp
  • A to T, chromosome 13 at 70,619,074 bp
  • A to C, chromosome 13 at 91,771,828 bp
  • T to C, chromosome 14 at 50,736,383 bp
  • A to G, chromosome 15 at 58,558,402 bp
  • A to G, chromosome 15 at 85,815,630 bp
  • G to A, chromosome 16 at 20,698,988 bp
  • T to C, chromosome 17 at 3,554,957 bp
  • T to C, chromosome 17 at 40,578,853 bp
  • T to C, chromosome 17 at 55,898,139 bp
  • T to C, chromosome 18 at 42,156,057 bp
  • G to A, chromosome 19 at 9,006,680 bp
  • T to C, chromosome 19 at 11,973,859 bp
  • A to T, chromosome 19 at 25,678,291 bp
  • C to T, chromosome 19 at 41,097,912 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0141 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038426-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.