Strain Name:
C57BL/6J-MtgxR0145Btlr/Mmmh
Stock Number:
038430-MU
Citation ID:
RRID:MMRRC_038430-MU
Other Names:
R0145 (G1), C57BL/6J-MtgxR0145Btlr
Major Collection:

Strain Information

Tyrp1
Name: tyrosinase-related protein 1
Synonyms: Tyrp, TRP-1, Oca3, isa, TRP1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22178
Homologene: 464
Btrc
Name: beta-transducin repeat containing protein
Synonyms: beta-TrCP, Fbw1a, Beta-Trcp1, SCF b-TRCP, Slimb
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12234
VEGA: 19
HGNC: HGNC:1144
Homologene: 39330
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, Acf7, trabeculin alpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11426
Homologene: 136191
Phf20
Name: PHD finger protein 20
Synonyms: 6820402O20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228829
Homologene: 9507
Cdk11b
Name: cyclin dependent kinase 11B
Synonyms: Cdc2l1, CDK11-p110, PITSLRE proteins, CDK11-p46, CDK11-p58, Cdc2l2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12537
Homologene: 22416
Rps6ka2
Name: ribosomal protein S6 kinase, polypeptide 2
Synonyms: 90kDa, Rsk3, p90rsk, Rps6ka-rs1, pp90rsk, D17Wsu134e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20112
VEGA: 17
Homologene: 100680
Cnot2
Name: CCR4-NOT transcription complex, subunit 2
Synonyms: 2810470K03Rik, 2600016M12Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 72068
HGNC: HGNC:7878
Homologene: 40953
Zfat
Name: zinc finger and AT hook domain containing
Synonyms: Zfat1, Zfp406, LOC380993
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 380993
Homologene: 16829
Prkab1
Name: protein kinase, AMP-activated, beta 1 non-catalytic subunit
Synonyms: 1300015D22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19079
HGNC: HGNC:9378
Homologene: 38160
Nacc1
Name: nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
Synonyms: 4930511N13Rik, Nac1, Btbd14b, 2010001H03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66830
VEGA: 8
Homologene: 12042
Utp4
Name: UTP4 small subunit processome component
Synonyms: Cirh1a, TEG-292, Tex292
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 21771
HGNC: HGNC:1983
Homologene: 40775
Zfp462
Name: zinc finger protein 462
Synonyms: 9430078C22Rik, Zfpip, Gt4-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242466
Homologene: 41430
Ranbp2
Name: RAN binding protein 2
Synonyms: A430087B05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19386
VEGA: 10
Homologene: 87808
Mon2
Name: MON2 homolog, regulator of endosome to Golgi trafficking
Synonyms: SF21, 2610528O22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67074
VEGA: 10
Homologene: 44309
Prrc2a
Name: proline-rich coiled-coil 2A
Synonyms: Wbp12, Bat2, D17H6S51E, G2, 3110039B05Rik, Bat-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 53761
Homologene: 10567
Bcas3
Name: BCAS3 microtubule associated cell migration factor
Synonyms: rudhira, breast carcinoma amplified sequence 3, Phaf2, 1500019F07Rik, 2610028P08Rik, K20D4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192197
Homologene: 9778
Ruvbl1
Name: RuvB-like AAA ATPase 1
Synonyms: Tip49a, Pontin52, 2510009G06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56505
Homologene: 37839
Ep300
Name: E1A binding protein p300
Synonyms: p300, KAT3B
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328572
HGNC: HGNC:3373
Homologene: 1094
Bmpr2
Name: bone morphogenetic protein receptor type 2
Synonyms: BMPRII, BMPR-II, 2610024H22Rik, BMP-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12168
HGNC: HGNC:1078
Homologene: 929
Pole
Name: polymerase (DNA directed), epsilon
Synonyms: pol-epsilon
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18973
HGNC: HGNC:9177
Homologene: 4539
Supt6
Name: SPT6, histone chaperone and transcription elongation factor
Synonyms: Supt6h, 5131400N11Rik, SPT6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20926
Homologene: 40661
Slc3a2
Name: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
Synonyms: Mgp-2hc, Cd98, 4F2HC, Ly-10, Mdu1, Ly-m10
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 17254
Homologene: 1795
Hacd3
Name: 3-hydroxyacyl-CoA dehydratase 3
Synonyms: Ptplad1, B-ind1, Hspc121
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 57874
VEGA: 9
Homologene: 9494
Nol8
Name: nucleolar protein 8
Synonyms: D13Ertd548e, 5730412B09Rik, 4921532D18Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 70930
VEGA: 13
Homologene: 41210
Tube1
Name: tubulin, epsilon 1
Synonyms: 2310061K05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71924
VEGA: 10
Homologene: 17762
Slc12a9
Name: solute carrier family 12 (potassium/chloride transporters), member 9
Synonyms: CIP1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 83704
Homologene: 5429
Tubgcp3
Name: tubulin, gamma complex component 3
Synonyms: Spc98p, GCP3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 259279
Homologene: 4609
Asxl3
Name: ASXL transcriptional regulator 3
Synonyms: D930044O18Rik, D430002O22Rik, C230079D11Rik, LOC381127
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 211961
Homologene: 19371
Sema4a
Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
Synonyms: SemB, Semab, SemB
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20351
Homologene: 8425
Lct
Name: lactase
Synonyms: LOC226413, LPH, Lphl
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226413
HGNC: HGNC:6530
Homologene: 124204
Cubn
Name: cubilin
Synonyms: intrinsic factor-cobalamin receptor, D2Wsu88e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Tnfaip2
Name: tumor necrosis factor, alpha-induced protein 2
Synonyms: Tnfip2, M-sec, Exoc3l3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 21928
Homologene: 4583
Tgm5
Name: transglutaminase 5
Synonyms: TGx, 2310007C07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74176
Homologene: 20899
Serpinb6e
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6e
Synonyms: SPI3B, Gm11396, ovalbumin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 435350
HGNC: HGNC:8950
Homologene: 50933
Cfap44
Name: cilia and flagella associated protein 44
Synonyms: 6330444M21Rik, Wdr52, D16Ertd642e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 212517
Homologene: 75085
Spata31e2
Name: spermatogenesis associated 31 subfamily E member 2
Synonyms: 4931408C20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210940
Homologene: 86827
Rab11fip1
Name: RAB11 family interacting protein 1 (class I)
Synonyms: 4833414G05Rik, 2010200K21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75767
Homologene: 11853
Nanos3
Name: nanos C2HC-type zinc finger 3
Synonyms: nos3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244551
Homologene: 65856
Cox8a
Name: cytochrome c oxidase subunit 8A
Synonyms: COX8L, COX VIII-L
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12868
VEGA: 19
HGNC: HGNC:2294
Homologene: 3006
Ngef
Name: neuronal guanine nucleotide exchange factor
Synonyms: Tims2, ephexin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 53972
HGNC: HGNC:7807
Homologene: 75120
1700017N19Rik
Name: RIKEN cDNA 1700017N19 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66605
Homologene: 45135
Pik3cg
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Synonyms: 5830428L06Rik, PI3Kgamma, PI(3)Kgamma, PI3Kgamma, p110gamma
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 30955
HGNC: HGNC:8978
Homologene: 68269
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: Dnahc7b, LOC227058
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227058
Homologene: 41287
Sun1
Name: Sad1 and UNC84 domain containing 1
Synonyms: Unc84a, 4632417G13Rik, 5730434D03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77053
Homologene: 11544
Zfp366
Name: zinc finger protein 366
Synonyms: DC-SCRIPT
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238803
Homologene: 17637
Cd248
Name: CD248 antigen, endosialin
Synonyms: Tem1, 2610111G01Rik, Cd164l1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 70445
VEGA: 19
Homologene: 10699
Or8i2
Name: olfactory receptor family 8 subfamily I member 2
Synonyms: MOR207-1, Olfr1104, GA_x6K02T2Q125-48508763-48507833
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258763
Homologene: 64916
Spart
Name: spartin
Synonyms: Spg20, TAHCCP1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229285
Chil3
Name: chitinase-like 3
Synonyms: Chi3l3, Ym1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12655
Homologene: 74931
Slc7a13
Name: solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
Synonyms: XAT2, 0610009O04Rik, AGT-1, AGT1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74087
Homologene: 23656
Aldoart1
Name: aldolase 1 A, retrogene 1
Synonyms: Aldoa-ps2, 4921524E03Rik, Aldo1-ps2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 353204
Homologene: 128442
Rims3
Name: regulating synaptic membrane exocytosis 3
Synonyms: A730060M23Rik, Rim3, Nim3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242662
Homologene: 8837
Bst1
Name: bone marrow stromal cell antigen 1
Synonyms: 114/A10, Ly65, Bp3, CD157, Bsta1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12182
HGNC: HGNC:1118
Homologene: 3198
Pus1
Name: pseudouridine synthase 1
Synonyms: MPUS1, mPus1p, A730013B20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56361
Homologene: 5931
Ficd
Name: FIC domain containing
Synonyms: D5Ertd40e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231630
Homologene: 5139
Vgf
Name: VGF nerve growth factor inducible
Synonyms: LOC381677
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381677
Homologene: 2536
Daglb
Name: diacylglycerol lipase, beta
Synonyms: E330036I19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231871
Homologene: 34715
Aqp1
Name: aquaporin 1
Synonyms: CHIP28
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11826
HGNC: HGNC:633
Homologene: 68051
Mmrn1
Name: multimerin 1
Synonyms: 4921530G03Rik, Emilin4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 70945
HGNC: HGNC:7178
Homologene: 49134
Cpne9
Name: copine family member IX
Synonyms: A730016F12Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 211232
Homologene: 84686
Pkp3
Name: plakophilin 3
Synonyms: 2310056L12Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56460
HGNC: HGNC:9025
Homologene: 5200
Tm6sf2
Name: transmembrane 6 superfamily member 2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 107770
Homologene: 77694
Cyba
Name: cytochrome b-245, alpha polypeptide
Synonyms: cytochrome beta-558, p22 phox, b558
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13057
HGNC: HGNC:2577
Homologene: 80
Fbxl2
Name: F-box and leucine-rich repeat protein 2
Synonyms: Fbl3, 2810423A21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72179
Homologene: 135814
Zup1
Name: zinc finger containing ubiquitin peptidase 1
Synonyms: 2700019D07Rik, Zufsp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 72580
VEGA: 10
Homologene: 12472
Lilrb4b
Name: leukocyte immunoglobulin-like receptor, subfamily B, member 4B
Synonyms: gp49, Lilr4b, Gp49a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14727
HGNC: HGNC:6608
Homologene: 86756
Cfap410
Name: cilia and flagella associated protein 410
Synonyms: 1810043G02Rik, D10Jhu13e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67884
HGNC: HGNC:1260
Homologene: 3619
Parpbp
Name: PARP1 binding protein
Synonyms: 4930547N16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 75317
Homologene: 49519
Actr6
Name: ARP6 actin-related protein 6
Synonyms: CDA12, ArpX, Arp6, 2010200J04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67019
VEGA: 10
Homologene: 6451
Or6c8
Name: olfactory receptor family 6 subfamily C member 8
Synonyms: GA_x6K02T2PULF-10765431-10764502, MOR115-1, Olfr767
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258315
Homologene: 105186
Rnf130
Name: ring finger protein 130
Synonyms: G1RZFP, G1RP, 2510042A13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 59044
Homologene: 41267
Ogfod3
Name: 2-oxoglutarate and iron-dependent oxygenase domain containing 3
Synonyms: 1110031I02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66179
Homologene: 11640
Ctsll3
Name: cathepsin L-like 3
Synonyms: 2310051M13Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 70202
VEGA: 13
Homologene: 134916
Arsb
Name: arylsulfatase B
Synonyms: As-1t, As-1s, 1110007C02Rik, As1-s, Asr-1, Ast-1, As1, As-1r, As1-r, As-1, As1-t
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 11881
VEGA: 13
HGNC: HGNC:714
Homologene: 73870
Gm6320
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Esm1
Name: endothelial cell-specific molecule 1
Synonyms: 0610042H23Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 71690
HGNC: HGNC:3466
Homologene: 5107
Gm5465
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Cyp4f39
Name: cytochrome P450, family 4, subfamily f, polypeptide 39
Synonyms: 4732474A20Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320997
VEGA: 17
Homologene: 69814
Zfp955a
Name: zinc finger protein 955A
Synonyms: AI842447
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 77652
VEGA: 17
Homologene: 104925
H2-Q2
Name: histocompatibility 2, Q region locus 2
Synonyms: H-2Q2, Gm11132
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15013
Homologene: 128352
Daam2
Name: dishevelled associated activator of morphogenesis 2
Synonyms: 2310016D11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 76441
VEGA: 17
Homologene: 69186
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 26,687,332 bp
  • T to G, chromosome 1 at 46,223,178 bp
  • AACACA to AACA, chromosome 1 at 59,867,580 bp
  • A to G, chromosome 1 at 87,540,648 bp
  • T to C, chromosome 1 at 128,327,895 bp
  • T to A, chromosome 2 at 13,306,432 bp
  • A to C, chromosome 2 at 87,021,790 bp
  • A to G, chromosome 2 at 121,077,581 bp
  • GTGTTTGTTTGTTTGTTTGTTTGTTT to GTGTTTGTTTGTTTGTTTGTTTGTTTGTTTGTTT, chromosome 2 at 156,287,770 bp
  • A to T, chromosome 3 at 55,127,671 bp
  • A to T, chromosome 3 at 88,451,422 bp
  • T to A, chromosome 3 at 106,160,478 bp
  • G to A, chromosome 4 at 19,818,782 bp
  • G to A, chromosome 4 at 55,010,529 bp
  • A to T, chromosome 4 at 72,851,339 bp
  • A to G, chromosome 4 at 80,840,778 bp
  • T to C, chromosome 4 at 120,887,026 bp
  • T to A, chromosome 4 at 123,387,397 bp
  • G to T, chromosome 4 at 155,641,619 bp
  • A to G, chromosome 5 at 43,819,072 bp
  • G to T, chromosome 5 at 110,324,425 bp
  • C to A, chromosome 5 at 110,774,854 bp
  • G to T, chromosome 5 at 113,738,819 bp
  • T to C, chromosome 5 at 116,018,085 bp
  • T to A, chromosome 5 at 137,031,482 bp
  • C to A, chromosome 5 at 137,315,288 bp
  • T to C, chromosome 5 at 139,241,411 bp
  • T to C, chromosome 5 at 143,474,608 bp
  • C to T, chromosome 6 at 55,346,687 bp
  • C to A, chromosome 6 at 60,973,010 bp
  • A to G, chromosome 6 at 88,484,459 bp
  • T to C, chromosome 6 at 113,300,601 bp
  • T to G, chromosome 7 at 141,089,763 bp
  • A to G, chromosome 7 at 141,795,275 bp
  • A to G, chromosome 8 at 12,657,561 bp
  • A to G, chromosome 8 at 27,143,324 bp
  • T to C, chromosome 8 at 70,077,868 bp
  • C to T, chromosome 8 at 84,176,134 bp
  • T to C, chromosome 8 at 84,674,875 bp
  • A to G, chromosome 8 at 106,894,669 bp
  • A to T, chromosome 8 at 122,427,238 bp
  • A to T, chromosome 9 at 65,004,242 bp
  • T to C, chromosome 9 at 113,985,325 bp
  • T to C, chromosome 10 at 33,943,713 bp
  • T to A, chromosome 10 at 39,145,602 bp
  • T to G, chromosome 10 at 51,484,518 bp
  • T to A, chromosome 10 at 58,480,046 bp
  • T to C, chromosome 10 at 77,983,556 bp
  • T to C, chromosome 10 at 88,093,009 bp
  • A to T, chromosome 10 at 89,728,178 bp
  • A to G, chromosome 10 at 100,601,921 bp
  • A to T, chromosome 10 at 116,517,368 bp
  • C to A, chromosome 10 at 123,013,512 bp
  • A to T, chromosome 10 at 129,079,363 bp
  • A to G, chromosome 11 at 50,071,219 bp
  • A to G, chromosome 11 at 78,208,236 bp
  • T to C, chromosome 11 at 85,359,610 bp
  • A to T, chromosome 11 at 121,195,070 bp
  • C to A, chromosome 12 at 32,204,322 bp
  • T to A, chromosome 12 at 111,445,858 bp
  • A to T, chromosome 13 at 33,841,060 bp
  • C to T, chromosome 13 at 49,662,447 bp
  • C to A, chromosome 13 at 60,798,595 bp
  • G to A, chromosome 13 at 93,862,287 bp
  • G to T, chromosome 13 at 99,229,540 bp
  • A to G, chromosome 13 at 112,994,372 bp
  • A to G, chromosome 13 at 113,216,696 bp
  • T to A, chromosome 14 at 79,453,024 bp
  • T to C, chromosome 15 at 68,187,099 bp
  • T to C, chromosome 15 at 81,616,127 bp
  • A to T, chromosome 16 at 44,468,372 bp
  • C to A, chromosome 17 at 7,262,186 bp
  • T to A, chromosome 17 at 32,486,960 bp
  • T to A, chromosome 17 at 33,242,456 bp
  • T to C, chromosome 17 at 35,155,820 bp
  • A to G, chromosome 17 at 35,345,176 bp
  • T to C, chromosome 17 at 49,480,778 bp
  • G to A, chromosome 18 at 22,453,605 bp
  • T to C, chromosome 19 at 5,069,023 bp
  • G to T, chromosome 19 at 7,215,418 bp
  • A to G, chromosome 19 at 8,708,073 bp
  • T to A, chromosome 19 at 45,423,173 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0145 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038430-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.