Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR0299Btlr/Mmmh
Stock Number:
038513-MU
Citation ID:
RRID:MMRRC_038513-MU
Other Names:
R0299 (G1), C57BL/6J-MtgxR0299Btlr
Major Collection:

Strain Information

Elp2
Name: elongator acetyltransferase complex subunit 2
Synonyms: Stat3-interacting protein, StIP1, Statip1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 58523
VEGA: 18
Homologene: 6019
Pzp
Name: PZP, alpha-2-macroglobulin like
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11287
Homologene: 104112
Nisch
Name: nischarin
Synonyms: 1200007D05Rik, 3202002H23Rik, edsn
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 64652
Homologene: 136161
Serpina9
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
Synonyms: Centerin, 2310014L03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 71907
Homologene: 23633
Carmil1
Name: capping protein regulator and myosin 1 linker 1
Synonyms: 1110037D04Rik, Lrrc16, Carmil, Lrrc16a
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68732
Homologene: 9757
Sik3
Name: SIK family kinase 3
Synonyms: 5730525O22Rik, 9030204A07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70661
Homologene: 57023
Suco
Name: SUN domain containing ossification factor
Synonyms: osteopotentia, Opt, AI848100
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226551
HGNC: HGNC:1240
Homologene: 32212
Ints8
Name: integrator complex subunit 8
Synonyms: D130008D20Rik, 2810013E07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72656
Homologene: 9888
Celf6
Name: CUGBP, Elav-like family member 6
Synonyms: 6330569O16Rik, Brunol6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76183
Homologene: 129318
Sppl3
Name: signal peptide peptidase 3
Synonyms: 4833416I09Rik, Usmg3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74585
Homologene: 15563
Pdcd10
Name: programmed cell death 10
Synonyms: TF-1 cell apoptosis related protein-15, Tfa15, 2410003B13Rik, CCM3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56426
HGNC: HGNC:8761
Homologene: 10505
Muc2
Name: mucin 2
Synonyms: 2010015E03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17831
HGNC: HGNC:7512
Homologene: 136755
Pdgfrb
Name: platelet derived growth factor receptor, beta polypeptide
Synonyms: CD140b, Pdgfr
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 18596
HGNC: HGNC:8804
Homologene: 1960
Adam32
Name: a disintegrin and metallopeptidase domain 32
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 353188
Homologene: 17021
Hepacam2
Name: HEPACAM family member 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101202
Homologene: 18724
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Degs1
Name: delta 4-desaturase, sphingolipid 1
Synonyms: Mdes, Des1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13244
Homologene: 55770
Btbd10
Name: BTB domain containing 10
Synonyms: Gmrp1, 1110056N09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68815
Homologene: 13009
Trub1
Name: TruB pseudouridine (psi) synthase family member 1
Synonyms: 9030425C13Rik, 2610009I02Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72133
VEGA: 19
Homologene: 34714
Gin1
Name: gypsy retrotransposon integrase 1
Synonyms: 4930429M06, 4930429M06Rik, Zh2c2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 252876
Homologene: 69238
Slamf7
Name: SLAM family member 7
Synonyms: novel Ly9, 4930560D03Rik, 19A, 19A24, CS1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75345
Homologene: 49660
Mecom
Name: MDS1 and EVI1 complex locus
Synonyms: ZNFPR1B1, Prdm3, MDS1-EVI1, Evi-1, D630039M04Rik, Jbo, Evi1, Mds1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14013
HGNC: HGNC:3498
Homologene: 21086
Sh3bgrl2
Name: SH3 domain binding glutamic acid-rich protein like 2
Synonyms: A930014C21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 212531
Homologene: 12876
Me2
Name: malic enzyme 2, NAD(+)-dependent, mitochondrial
Synonyms: D030040L20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 107029
VEGA: 18
HGNC: HGNC:6984
Homologene: 37615
Dnah1
Name: dynein, axonemal, heavy chain 1
Synonyms: MDHC7, E030034C22Rik, B230373P09Rik, Dnahc1, G1-415-19, ferf1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110084
VEGA: 14
HGNC: HGNC:2940
Homologene: 67131
Hps6
Name: HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
Synonyms: 5330434M19Rik, ruby eye, ru, BLOC-2, Hermansky-Pudlak syndrome 6
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20170
VEGA: 19
Homologene: 11691
Abca13
Name: ATP-binding cassette, sub-family A member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268379
Homologene: 27991
Shtn1
Name: shootin 1
Synonyms: shootin1, 4930506M07Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 71653
VEGA: 19
Homologene: 41249
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Trpm3
Name: transient receptor potential cation channel, subfamily M, member 3
Synonyms: B930001P07Rik, 6330504P12Rik, MLSN2, melastatin 2, LTRPC3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226025
VEGA: 19
Homologene: 62287
Tecta
Name: tectorin alpha
Synonyms: [a]-tectorin, Tctna
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 21683
Homologene: 3955
Ugcg
Name: UDP-glucose ceramide glucosyltransferase
Synonyms: GlcT-1, Epcs21, Ugcgl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22234
Homologene: 37763
Il1r2
Name: interleukin 1 receptor, type II
Synonyms: IL-1 receptor beta chain, CD121b, Il1r-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16178
HGNC: HGNC:5994
Homologene: 7783
Dock10
Name: dedicator of cytokinesis 10
Synonyms: Jr5, Jr4, ZIZ3, 9330153B10Rik, A630054M16Rik, Zizimin3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210293
Homologene: 45952
Ap4b1
Name: adaptor-related protein complex AP-4, beta 1
Synonyms: AP-4 beta-4, 1810038H16Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67489
HGNC: HGNC:572
Homologene: 38203
Adcy8
Name: adenylate cyclase 8
Synonyms: AC8
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 11514
VEGA: 15
HGNC: HGNC:239
Homologene: 37443
Pcsk6
Name: proprotein convertase subtilisin/kexin type 6
Synonyms: PACE4, SPC4, b2b2830Clo
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18553
HGNC: HGNC:8569
Homologene: 20569
A2ml1
Name: alpha-2-macroglobulin like 1
Synonyms: Ovos2, BC048546
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232400
Homologene: 45969
Fshr
Name: follicle stimulating hormone receptor
Synonyms: follicle-stimulating hormone receptor, Follitropin receptor, FSH-R
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14309
VEGA: 17
HGNC: HGNC:3969
Homologene: 117
Tram2
Name: translocating chain-associating membrane protein 2
Synonyms: C330003D03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 170829
Homologene: 8183
Or10ak14
Name: olfactory receptor family 10 subfamily AK member 14
Synonyms: MOR259-4P, GA_x6K02T2QD9B-18795136-18796077, MOR259-4P, MOR259-9, Olfr1524-ps1, Olfr1338
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258259
Homologene: 115537
Acp3
Name: acid phosphatase 3
Synonyms: PAP, A030005E02Rik, Acpp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56318
HGNC: HGNC:125
Homologene: 55552
Or10ak9
Name: olfactory receptor family 10 subfamily AK member 9
Synonyms: GA_x6K02T2QD9B-18670866-18669913, MOR259-3P, Olfr1331
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258159
Homologene: 134082
4933427I04Rik
Name: Riken cDNA 4933427I04 gene
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 115489902
VEGA: 4
Col15a1
Name: collagen, type XV, alpha 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12819
HGNC: HGNC:2192
Homologene: 1396
Arg2
Name: arginase type II
Synonyms: AII
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 11847
HGNC: HGNC:664
Homologene: 906
Serpina1d
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1D
Synonyms: PI4, Spi1-4
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20703
HGNC: HGNC:8941
Homologene: 20103
Mss51
Name: MSS51 mitochondrial translational activator
Synonyms: 4833444M15Rik, Zmynd17
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 74843
VEGA: 14
Homologene: 27997
Rad21
Name: RAD21 cohesin complex component
Synonyms: SCC1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19357
VEGA: 15
HGNC: HGNC:9811
Homologene: 38161
Gm6327
Name: predicted gene 6327
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Cd96
Name: CD96 antigen
Synonyms: Tactile, 1700109I12Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 84544
Homologene: 68489
4930503L19Rik
Name: RIKEN cDNA 4930503L19 gene
Synonyms: Las2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 269033
Homologene: 52120
Neto1
Name: neuropilin (NRP) and tolloid (TLL)-like 1
Synonyms: C130005O10Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 246317
VEGA: 18
Homologene: 16367
Col16a1
Name: collagen, type XVI, alpha 1
Synonyms: [a]1 (XVI) collagen, 2700007F12Rik, A530052M23Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 107581
HGNC: HGNC:2193
Homologene: 1397
Il18rap
Name: interleukin 18 receptor accessory protein
Synonyms: AcPL accessory protein-like)
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16174
HGNC: HGNC:5989
Homologene: 2859
Atxn1
Name: ataxin 1
Synonyms: Atx1, Sca1, 2900016G23Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20238
VEGA: 13
Homologene: 281
Pelo
Name: pelota mRNA surveillance and ribosome rescue factor
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105083
VEGA: 13
HGNC: HGNC:8829
Homologene: 6835
Plxnc1
Name: plexin C1
Synonyms: vespr, 2510048K12Rik, CD232
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 54712
HGNC: HGNC:9106
Homologene: 4211
Krtap4-23
Name: keratin associated protein 4-23
Synonyms: Gm11596
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 670464
Homologene: 124486
Hsd17b7
Name: hydroxysteroid (17-beta) dehydrogenase 7
Synonyms: ERG27
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 15490
HGNC: HGNC:5215
Homologene: 40728
Ptpru
Name: protein tyrosine phosphatase receptor type U
Synonyms: Ptprl, RPTPlambda
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Vmn1r25
Name: vomeronasal 1 receptor 25
Synonyms: V1rc8
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113865
Homologene: 137652
Clec2h
Name: C-type lectin domain family 2, member h
Synonyms: Clrf
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 94071
Homologene: 131164
Zfp821
Name: zinc finger protein 821
Synonyms: 4930566A11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75871
Homologene: 32345
Frk
Name: fyn-related kinase
Synonyms: BSK/IYK, GTK
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14302
VEGA: 10
HGNC: HGNC:3955
Homologene: 48065
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 21,004,244 bp
  • T to A, chromosome 1 at 40,123,149 bp
  • A to T, chromosome 1 at 40,525,058 bp
  • T to C, chromosome 1 at 80,536,929 bp
  • T to A, chromosome 1 at 97,783,016 bp
  • G to A, chromosome 1 at 161,853,810 bp
  • G to A, chromosome 1 at 169,959,794 bp
  • G to A, chromosome 1 at 171,648,931 bp
  • A to T, chromosome 1 at 182,279,271 bp
  • A to G, chromosome 3 at 29,980,411 bp
  • T to C, chromosome 3 at 75,527,651 bp
  • T to C, chromosome 3 at 103,809,946 bp
  • C to A, chromosome 4 at 11,246,097 bp
  • A to T, chromosome 4 at 47,262,950 bp
  • G to C, chromosome 4 at 59,217,036 bp
  • A to T, chromosome 4 at 118,754,535 bp
  • A to G, chromosome 4 at 118,869,416 bp
  • A to T, chromosome 4 at 123,860,822 bp
  • TCCCC to TCCC, chromosome 4 at 130,058,318 bp
  • G to A, chromosome 4 at 131,803,387 bp
  • T to A, chromosome 5 at 115,088,994 bp
  • A to G, chromosome 6 at 3,476,121 bp
  • T to A, chromosome 6 at 57,978,509 bp
  • A to G, chromosome 6 at 128,495,330 bp
  • T to G, chromosome 6 at 128,553,232 bp
  • T to C, chromosome 6 at 128,670,895 bp
  • T to C, chromosome 7 at 66,039,043 bp
  • A to T, chromosome 7 at 113,329,878 bp
  • C to T, chromosome 7 at 141,752,729 bp
  • A to T, chromosome 8 at 24,872,770 bp
  • G to T, chromosome 8 at 109,724,230 bp
  • T to C, chromosome 9 at 42,352,063 bp
  • T to C, chromosome 9 at 46,208,740 bp
  • C to A, chromosome 9 at 59,602,878 bp
  • A to G, chromosome 9 at 83,577,559 bp
  • T to C, chromosome 9 at 104,320,002 bp
  • T to C, chromosome 10 at 34,484,371 bp
  • C to T, chromosome 10 at 94,849,821 bp
  • G to A, chromosome 11 at 9,298,076 bp
  • G to A, chromosome 11 at 99,792,944 bp
  • A to G, chromosome 12 at 79,147,612 bp
  • A to T, chromosome 12 at 103,765,757 bp
  • T to C, chromosome 12 at 104,001,470 bp
  • T to A, chromosome 13 at 24,082,020 bp
  • A to G, chromosome 13 at 45,567,169 bp
  • A to T, chromosome 13 at 115,088,903 bp
  • T to A, chromosome 14 at 20,484,688 bp
  • A to G, chromosome 14 at 31,171,924 bp
  • C to T, chromosome 14 at 31,276,158 bp
  • A to T, chromosome 15 at 51,965,030 bp
  • T to A, chromosome 15 at 64,716,166 bp
  • T to C, chromosome 16 at 12,761,197 bp
  • A to T, chromosome 16 at 32,750,195 bp
  • T to C, chromosome 16 at 46,038,579 bp
  • T to A, chromosome 17 at 30,715,509 bp
  • C to G, chromosome 17 at 89,009,285 bp
  • T to C, chromosome 18 at 24,634,409 bp
  • T to A, chromosome 18 at 61,068,852 bp
  • G to A, chromosome 18 at 70,469,482 bp
  • A to G, chromosome 18 at 73,770,673 bp
  • G to A, chromosome 18 at 86,461,320 bp
  • T to C, chromosome 19 at 22,986,873 bp
  • G to A, chromosome 19 at 46,004,232 bp
  • A to G, chromosome 19 at 57,483,625 bp
  • T to C, chromosome 19 at 59,018,951 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0299 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038513-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.