Strain Name:
C57BL/6J-MtgxR0306Btlr/Mmmh
Stock Number:
038517-MU
Citation ID:
RRID:MMRRC_038517-MU
Other Names:
R0306 (G1), C57BL/6J-MtgxR0306Btlr
Major Collection:

Gene Information

Dnmt3a
Name: DNA methyltransferase 3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13435
HGNC: HGNC:2978
Homologene: 7294
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 208440
Homologene: 40996
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77595
Homologene: 28122
Fmn2
Name: formin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 54418
Homologene: 137334
Trpc4ap
Name: transient receptor potential cation channel, subfamily C, member 4 associated protein
Synonyms: Trp4-associated protein TAP1, Trrp4ap, D2Ertd113e, 4833429F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56407
Homologene: 9224
Sorbs1
Name: sorbin and SH3 domain containing 1
Synonyms: c-Cbl-associated protein, CAP, Sh3d5, 9530001P15Rik, 2310065E01Rik, Ponsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20411
VEGA: 19
Homologene: 83252
Nav2
Name: neuron navigator 2
Synonyms: POMFIL2, Unc53H2, HELAD1, RAINB2, 5330421F07Rik, Rainb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78286
Homologene: 52330
Ddx52
Name: DExD box helicase 52
Synonyms: 2700029C06Rik, ROK1, DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 78394
Homologene: 5093
Ttll4
Name: tubulin tyrosine ligase-like family, member 4
Synonyms: 4632407P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67534
Homologene: 8764
Psmg1
Name: proteasome (prosome, macropain) assembly chaperone 1
Synonyms: Dscr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 56088
HGNC: HGNC:3043
Homologene: 2759
Kdm3b
Name: KDM3B lysine (K)-specific demethylase 3B
Synonyms: 5830462I21Rik, JHDM2B, Jmjd1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 277250
VEGA: 18
HGNC: HGNC:1337
Homologene: 41145
Unc5b
Name: unc-5 netrin receptor B
Synonyms: 6330415E02Rik, Unc5h2, D10Bwg0792e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 107449
VEGA: 10
Homologene: 32538
Paxbp1
Name: PAX3 and PAX7 binding protein 1
Synonyms: 1810007M14Rik, Pax3/7bp, Gcfc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67367
Homologene: 9604
Zfp142
Name: zinc finger protein 142
Synonyms: 9330177B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 77264
Homologene: 3723
Noc3l
Name: NOC3 like DNA replication regulator
Synonyms: Fad24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 57753
VEGA: 19
Homologene: 39642
Prdm10
Name: PR domain containing 10
Synonyms: tristanin, LOC382066
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382066
Homologene: 45718
Cd209a
Name: CD209a antigen
Synonyms: CIRE, CD209, Dcsign, DC-SIGN1, DC-SIGN, SIGNR5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 170786
Homologene: 129771
Jag1
Name: jagged 1
Synonyms: Serrate-1, Headturner, Htu, ABE2, Ozz, Gsfabe2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16449
HGNC: HGNC:6188
Homologene: 180
Il15
Name: interleukin 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16168
HGNC: HGNC:5977
Homologene: 487
C030017K20Rik
Name: RIKEN cDNA C030017K20 gene
Synonyms: LOC381581
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: b2b012Clo, Jbts17, Hug, 2410089E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 73692
Homologene: 11315
Slc22a1
Name: solute carrier family 22 (organic cation transporter), member 1
Synonyms: Lx1, Oct1, Orct, Oct1, Orct1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20517
VEGA: 17
Homologene: 20665
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Ces1f
Name: carboxylesterase 1F
Synonyms: TGH-2, CesML1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234564
HGNC: HGNC:1863
Homologene: 134311
Slc44a5
Name: solute carrier family 44, member 5
Synonyms: LOC242259
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242259
Homologene: 72094
Bspry
Name: B-box and SPRY domain containing
Synonyms: zetin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 192120
Homologene: 9781
Stk35
Name: serine/threonine kinase 35
Synonyms: CLP-36 interacting kinase, CLIK1, 1700054C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67333
Homologene: 15441
Sorbs2
Name: sorbin and SH3 domain containing 2
Synonyms: 9430041O17Rik, 2010203O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234214
Homologene: 83295
Tulp2
Name: tubby-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56734
Homologene: 2492
Defb26
Name: defensin beta 26
Synonyms: EG654457
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 654457
Homologene: 86850
Nsun4
Name: NOL1/NOP2/Sun domain family, member 4
Synonyms: 2310010O12Rik, 2810405F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72181
Homologene: 12455
Cfap52
Name: cilia and flagella associated protein 52
Synonyms: 4933417B11Rik, 1700019F09Rik, Wdr16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71860
Homologene: 12416
Mep1a
Name: meprin 1 alpha
Synonyms: meprin A alpha-subunit, meprin alpha, Mep-1a, Mep-1, Mep1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17287
HGNC: HGNC:7015
Homologene: 31323
Gm19684
Name: predicted gene, 19684
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
BC028528
Name: cDNA sequence BC028528
Synonyms: L259
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229600
Homologene: 49773
Smarca2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Synonyms: brm, Snf2l2, 2610209L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67155
Homologene: 2308
Syt10
Name: synaptotagmin X
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 54526
Homologene: 10303
Olfr1044
Name: olfactory receptor 1044
Synonyms: GA_x6K02T2Q125-47640742-47639798, MOR185-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259013
Homologene: 100542
Tcam1
Name: testicular cell adhesion molecule 1
Synonyms: 4930570F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75870
Homologene: 123944
Olfr473
Name: olfactory receptor 473
Synonyms: GA_x6K02T2PBJ9-10262759-10263691, MOR204-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258771
Homologene: 74116
Dytn
Name: dystrotelin
Synonyms: LOC241073
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241073
Homologene: 104042
Morn5
Name: MORN repeat containing 5
Synonyms: 1700010A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75495
Homologene: 16510
Ptpmt1
Name: protein tyrosine phosphatase, mitochondrial 1
Synonyms: 1110001D10Rik, PLIP, 2810004N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66461
Homologene: 11973
Shox2
Name: short stature homeobox 2
Synonyms: Prx3, Og12x, 6330543G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20429
Homologene: 68535
Doxl2
Name: diamine oxidase-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243376
Homologene: 19443
Chst8
Name: carbohydrate sulfotransferase 8
Synonyms: 1500011J21Rik, GalNAc4ST-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68947
Homologene: 41483
Zfp819
Name: zinc finger protein 819
Synonyms: 4930427I11Rik, 4933405K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74400
Homologene: 128446
Olfr571
Name: olfactory receptor 571
Synonyms: GA_x6K02T2PBJ9-5620890-5619922, MOR21-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259089
Homologene: 17498
Ddx49
Name: DEAD box helicase 49
Synonyms: R27090_2, DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234374
Homologene: 41308
Prkcsh
Name: protein kinase C substrate 80K-H
Synonyms: 80K-H, hepatocystin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19089
VEGA: 9
HGNC: HGNC:9411
Homologene: 2056
Slc9a9
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 9
Synonyms: 5730527A11Rik, Nhe9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 331004
Homologene: 69753
Ptprb
Name: protein tyrosine phosphatase, receptor type, B
Synonyms: 3230402H02Rik, VE-PTP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19263
VEGA: 10
HGNC: HGNC:9665
Homologene: 2125
Gal3st1
Name: galactose-3-O-sulfotransferase 1
Synonyms: galactosylceramide sulfotransferase, 3'-phosphoadenylylsulfate-galactosylceramide 3'-sulfotransferase, GalCer sulfotransferase, Gcst, Cst
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53897
Homologene: 3574
Serpinf1
Name: serine (or cysteine) peptidase inhibitor, clade F, member 1
Synonyms: EPC-1, Pedf, Sdf3, pigment epithelium derived factor, Pedfl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20317
HGNC: HGNC:8824
Homologene: 1965
Parp14
Name: poly (ADP-ribose) polymerase family, member 14
Synonyms: 1600029O10Rik, collaborator of Stat6, CoaSt6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 547253
Homologene: 19697
Vmn1r230
Name: vomeronasal 1 receptor 230
Synonyms: V1re8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 171231
Homologene: 136306
Lrfn2
Name: leucine rich repeat and fibronectin type III domain containing 2
Synonyms: 5730420O05Rik, SALM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70530
Homologene: 19182
Vmn2r118
Name: vomeronasal 2, receptor 118
Synonyms: EG668547, Vmn2r119, EG383258
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 383258
Homologene: 129687
Srp19
Name: signal recognition particle 19
Synonyms: 2310020D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 66384
Homologene: 2361
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 63,685,113 bp
  • C to T, chromosome 1 at 74,570,182 bp
  • G to A, chromosome 1 at 74,696,757 bp
  • T to C, chromosome 1 at 174,609,484 bp
  • T to C, chromosome 2 at 36,054,974 bp
  • T to A, chromosome 2 at 86,171,716 bp
  • A to G, chromosome 2 at 90,914,186 bp
  • A to G, chromosome 2 at 112,775,655 bp
  • T to A, chromosome 2 at 129,801,763 bp
  • C to T, chromosome 2 at 137,085,935 bp
  • T to A, chromosome 2 at 152,507,968 bp
  • A to G, chromosome 2 at 155,636,260 bp
  • T to C, chromosome 3 at 66,973,834 bp
  • T to C, chromosome 3 at 90,207,368 bp
  • C to T, chromosome 3 at 95,889,820 bp
  • A to G, chromosome 3 at 154,270,001 bp
  • T to C, chromosome 4 at 62,496,157 bp
  • A to T, chromosome 4 at 116,052,822 bp
  • G to A, chromosome 4 at 155,465,439 bp
  • T to C, chromosome 6 at 48,976,086 bp
  • T to C, chromosome 7 at 34,675,298 bp
  • C to A, chromosome 7 at 43,617,197 bp
  • C to T, chromosome 7 at 45,518,576 bp
  • C to A, chromosome 7 at 49,545,903 bp
  • A to T, chromosome 7 at 102,909,803 bp
  • A to T, chromosome 7 at 107,933,700 bp
  • A to G, chromosome 8 at 3,745,535 bp
  • A to T, chromosome 8 at 45,795,730 bp
  • A to G, chromosome 8 at 70,294,672 bp
  • T to A, chromosome 8 at 82,334,454 bp
  • T to C, chromosome 8 at 93,276,544 bp
  • T to C, chromosome 9 at 22,006,526 bp
  • C to A, chromosome 9 at 31,316,224 bp
  • A to T, chromosome 9 at 95,137,934 bp
  • C to A, chromosome 10 at 60,779,658 bp
  • T to C, chromosome 10 at 116,343,988 bp
  • T to A, chromosome 11 at 3,998,546 bp
  • T to C, chromosome 11 at 67,954,070 bp
  • T to C, chromosome 11 at 75,413,935 bp
  • G to T, chromosome 11 at 83,944,648 bp
  • G to A, chromosome 11 at 106,284,078 bp
  • A to G, chromosome 12 at 3,866,096 bp
  • T to A, chromosome 13 at 9,604,599 bp
  • T to C, chromosome 15 at 8,179,889 bp
  • T to G, chromosome 15 at 89,826,988 bp
  • A to G, chromosome 16 at 35,856,574 bp
  • A to G, chromosome 16 at 91,022,115 bp
  • A to G, chromosome 16 at 95,987,340 bp
  • A to G, chromosome 17 at 12,662,598 bp
  • T to A, chromosome 17 at 20,846,633 bp
  • A to T, chromosome 17 at 36,127,408 bp
  • A to T, chromosome 17 at 43,502,643 bp
  • A to T, chromosome 17 at 49,096,255 bp
  • A to C, chromosome 17 at 55,608,616 bp
  • T to C, chromosome 18 at 34,334,576 bp
  • C to A, chromosome 18 at 34,804,017 bp
  • T to A, chromosome 19 at 26,640,613 bp
  • T to C, chromosome 19 at 38,807,650 bp
  • T to C, chromosome 19 at 40,344,411 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0306 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038517-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.