Strain Name:
C57BL/6J-MtgxR0358Btlr/Mmmh
Stock Number:
038564-MU
Citation ID:
RRID:MMRRC_038564-MU
Other Names:
R0358 (G1), C57BL/6J-MtgxR0358Btlr
Major Collection:

Gene Information

Trim32
Name: tripartite motif-containing 32
Synonyms: 3f3, 1810045E12Rik, Zfp117, BBS11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69807
Homologene: 36327
Pef1
Name: penta-EF hand domain containing 1
Synonyms: 2600002E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67898
Homologene: 56569
Cep83
Name: centrosomal protein 83
Synonyms: 2600001G24Rik, 5730513H21Rik, 4921537D05Rik, Ccdc41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77048
VEGA: 10
Homologene: 9396
Terf1
Name: telomeric repeat binding factor 1
Synonyms: Trf1, Trbf1, Pin2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21749
Homologene: 7570
Dhx38
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 38
Synonyms: Prp16, Ddx38, 5730550P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 64340
Homologene: 8512
Tut7
Name: terminal uridylyl transferase 7
Synonyms: 6030448M23Rik, Tent3b, Zcchc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 214290
VEGA: 13
Homologene: 51941
Fbxl17
Name: F-box and leucine-rich repeat protein 17
Synonyms: Fbx13, C130023C01Rik, 6330576B01Rik, Fbxo13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 50758
Homologene: 79859
Eif2ak4
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms: GCN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27103
Homologene: 40891
Nup214
Name: nucleoporin 214
Synonyms: D2H9S46E, CAN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227720
HGNC: HGNC:8064
Homologene: 38008
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: U5-116kD, 116kDa, Snrp116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20624
Homologene: 3133
Ppp1r8
Name: protein phosphatase 1, regulatory subunit 8
Synonyms: 6330548N22Rik, NIPP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100336
HGNC: HGNC:9296
Homologene: 8555
Trim66
Name: tripartite motif-containing 66
Synonyms: D7H11orf29, Tif1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330627
Homologene: 28044
Arhgap23
Name: Rho GTPase activating protein 23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 58996
Homologene: 104145
Phrf1
Name: PHD and ring finger domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101471
Homologene: 16377
Cul7
Name: cullin 7
Synonyms: p193, 2510004L20Rik, p185, C230011P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66515
Homologene: 56683
Zfp451
Name: zinc finger protein 451
Synonyms: Kiaa0576-hp, 4933435G09Rik, 4930515K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98403
Homologene: 9188
Trpv4
Name: transient receptor potential cation channel, subfamily V, member 4
Synonyms: VR-OAC, Trp12, 0610033B08Rik, OTRPC4, VROAC, VRL-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 63873
Homologene: 11003
Larp7
Name: La ribonucleoprotein domain family, member 7
Synonyms: D3Wsu161e, C330027G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 28036
Homologene: 88843
Gcnt2
Name: glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
Synonyms: IGnTC, IGnTB, IGnTA, 5330430K10Rik, IGnT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14538
VEGA: 13
HGNC: HGNC:4204
Homologene: 41535
Cars
Name: cysteinyl-tRNA synthetase
Synonyms: CA3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 27267
HGNC: HGNC:1493
Homologene: 1328
Psmd11
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Synonyms: P44.5, S9, 1810019E17Rik, C78232, 2810055C24Rik, 2610024G20Rik, 1700089D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69077
HGNC: HGNC:9556
Homologene: 2108
Cnnm3
Name: cyclin M3
Synonyms: Acdp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 94218
HGNC: HGNC:104
Homologene: 23029
Nrbp1
Name: nuclear receptor binding protein 1
Synonyms: B230344L17Rik, Nrbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 192292
HGNC: HGNC:7993
Homologene: 8373
Abca16
Name: ATP-binding cassette, sub-family A (ABC1), member 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233810
Homologene: 132942
Atp6v1c2
Name: ATPase, H+ transporting, lysosomal V1 subunit C2
Synonyms: 1110038G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68775
Homologene: 15866
Aqp4
Name: aquaporin 4
Synonyms: aquaporin-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11829
VEGA: 18
HGNC: HGNC:637
Homologene: 37507
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: 9330101J02Rik, Ttc40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212124
Egln3
Name: egl-9 family hypoxia-inducible factor 3
Synonyms: SM-20, 2610021G09Rik, Phd3, Hif-p4h-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 112407
Homologene: 32531
Akap3
Name: A kinase (PRKA) anchor protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11642
HGNC: HGNC:373
Homologene: 4688
Ptprd
Name: protein tyrosine phosphatase, receptor type, D
Synonyms: 3000002J10Rik, B230219D21Rik, 1110002J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19266
HGNC: HGNC:9668
4932431P20Rik
Name: RIKEN cDNA 4932431P20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 114675
Ttll7
Name: tubulin tyrosine ligase-like family, member 7
Synonyms: 1110049N09Rik, 4921517B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70892
Homologene: 41578
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC269160, LOC381317, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241516
Homologene: 110349
Arhgef25
Name: Rho guanine nucleotide exchange factor (GEF) 25
Synonyms: 2410008H17Rik, GEFT, D10Ertd610e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 52666
VEGA: 10
Homologene: 32691
Tmem63a
Name: transmembrane protein 63a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208795
Homologene: 101673
Abcb1b
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 1B
Synonyms: Mdr1, Mdr1b, mdr, Pgy1, Pgy-1, Abcb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18669
Homologene: 69084
Ache
Name: acetylcholinesterase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11423
HGNC: HGNC:108
Homologene: 543
Gpr22
Name: G protein-coupled receptor 22
Synonyms: 2900068K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 73010
HGNC: HGNC:4477
Homologene: 18420
Ptk6
Name: PTK6 protein tyrosine kinase 6
Synonyms: Sik, Tksk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20459
HGNC: HGNC:9617
Homologene: 68494
Mep1a
Name: meprin 1 alpha
Synonyms: meprin A alpha-subunit, meprin alpha, Mep-1a, Mep-1, Mep1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17287
HGNC: HGNC:7015
Homologene: 31323
Mylk
Name: myosin, light polypeptide kinase
Synonyms: telokin, Mlck, MLCK210, MLCK108, 9530072E15Rik, A930019C19Rik, nmMlck
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 107589
HGNC: HGNC:7590
Homologene: 14202
Il18rap
Name: interleukin 18 receptor accessory protein
Synonyms: AcPL accessory protein-like)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16174
HGNC: HGNC:5989
Homologene: 2859
Rnf130
Name: ring finger protein 130
Synonyms: G1RP, 2510042A13Rik, G1RZFP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 59044
Homologene: 41267
Dhrs2
Name: dehydrogenase/reductase member 2
Synonyms: SDR family, 5430405K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71412
Homologene: 69438
Rhbdl3
Name: rhomboid like 3
Synonyms: Ventrhoid, Vrho, Rhbdl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246104
Homologene: 34700
Olfr149
Name: olfactory receptor 149
Synonyms: M31, GA_x6K02T2PVTD-33400306-33399371, MOR224-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235256
VEGA: 9
Homologene: 28452
Gbp2b
Name: guanylate binding protein 2b
Synonyms: Mag-1, Mpa-1, Gbp-1, Mpa1, Gbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14468
HGNC: HGNC:4184
Homologene: 137233
Ppig
Name: peptidyl-prolyl isomerase G (cyclophilin G)
Synonyms: SRCyp, B230312B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228005
Homologene: 3520
S100a13
Name: S100 calcium binding protein A13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20196
Homologene: 7523
Gpatch3
Name: G patch domain containing 3
Synonyms: D930035B09Rik, Gpatc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242691
Homologene: 11122
Olfr532
Name: olfactory receptor 532
Synonyms: GA_x6K02T2PBJ9-42570051-42569122, MOR251-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259028
Homologene: 133605
Ankle1
Name: ankyrin repeat and LEM domain containing 1
Synonyms: 8430438L13Rik, Ankrd41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234396
Homologene: 17562
Gm9797
Name: predicted pseudogene 9797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100039343
VEGA: 10
Slc22a16
Name: solute carrier family 22 (organic cation transporter), member 16
Synonyms: FLIPT2, OKB1, OCT6, CT2, 4921504E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70840
Homologene: 41957
Olfr1394
Name: olfactory receptor 1394
Synonyms: GA_x6K02T2QP88-6274566-6273628, MOR280-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258273
Homologene: 138305
Olfr725
Name: olfactory receptor 725
Synonyms: GA_x6K02T2PMLR-5725741-5724776, MOR246-3, MOR246-7_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258314
Homologene: 44957
Mrgprh
Name: MAS-related GPR, member H
Synonyms: MrgH, Gpr90
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 80978
VEGA: 17
Homologene: 12758
Tcte1
Name: t-complex-associated testis expressed 1
Synonyms: Tcte-1, D17Sil1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21645
VEGA: 17
Homologene: 8434
4921513D11Rik
Name: RIKEN cDNA 4921513D11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 15,805,838 bp
  • T to A, chromosome 1 at 33,777,729 bp
  • T to A, chromosome 1 at 36,521,222 bp
  • A to T, chromosome 1 at 40,549,042 bp
  • T to A, chromosome 1 at 180,956,423 bp
  • T to G, chromosome 1 at 188,537,780 bp
  • G to A, chromosome 2 at 32,004,300 bp
  • A to G, chromosome 2 at 69,743,598 bp
  • A to T, chromosome 2 at 82,983,333 bp
  • A to G, chromosome 2 at 118,463,929 bp
  • G to T, chromosome 2 at 181,198,522 bp
  • A to T, chromosome 3 at 90,515,992 bp
  • A to G, chromosome 3 at 127,547,088 bp
  • A to T, chromosome 3 at 142,606,789 bp
  • A to G, chromosome 3 at 146,944,116 bp
  • G to A, chromosome 4 at 65,613,254 bp
  • T to C, chromosome 4 at 75,944,989 bp
  • A to G, chromosome 4 at 130,127,387 bp
  • G to T, chromosome 4 at 132,834,728 bp
  • A to G, chromosome 4 at 133,577,904 bp
  • T to C, chromosome 5 at 8,821,423 bp
  • T to A, chromosome 5 at 31,244,887 bp
  • A to G, chromosome 5 at 114,630,432 bp
  • A to G, chromosome 5 at 137,290,373 bp
  • T to A, chromosome 6 at 126,866,812 bp
  • A to T, chromosome 7 at 29,532,211 bp
  • G to A, chromosome 7 at 109,460,176 bp
  • A to T, chromosome 7 at 120,544,716 bp
  • A to G, chromosome 7 at 139,651,533 bp
  • G to T, chromosome 7 at 140,418,943 bp
  • A to G, chromosome 7 at 141,258,304 bp
  • A to T, chromosome 7 at 143,588,482 bp
  • A to G, chromosome 8 at 71,407,545 bp
  • A to T, chromosome 8 at 109,552,462 bp
  • A to G, chromosome 9 at 39,702,001 bp
  • A to T, chromosome 10 at 11,609,344 bp
  • T to G, chromosome 10 at 40,587,492 bp
  • A to T, chromosome 10 at 94,719,731 bp
  • A to T, chromosome 10 at 127,184,453 bp
  • T to A, chromosome 11 at 49,160,244 bp
  • T to A, chromosome 11 at 50,071,282 bp
  • G to T, chromosome 11 at 80,353,631 bp
  • G to A, chromosome 11 at 80,462,684 bp
  • G to A, chromosome 11 at 97,463,588 bp
  • A to G, chromosome 11 at 102,864,801 bp
  • T to C, chromosome 12 at 17,284,960 bp
  • T to C, chromosome 12 at 31,709,982 bp
  • T to C, chromosome 12 at 54,203,296 bp
  • G to T, chromosome 13 at 40,860,853 bp
  • T to C, chromosome 13 at 59,782,104 bp
  • A to T, chromosome 14 at 50,035,286 bp
  • G to A, chromosome 14 at 55,236,117 bp
  • G to C, chromosome 16 at 34,879,475 bp
  • T to A, chromosome 17 at 12,877,350 bp
  • A to G, chromosome 17 at 43,478,950 bp
  • A to T, chromosome 17 at 45,535,285 bp
  • G to A, chromosome 17 at 46,663,744 bp
  • G to A, chromosome 17 at 63,356,851 bp
  • G to A, chromosome 17 at 79,628,156 bp
  • T to C, chromosome 18 at 15,398,245 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0358 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038564-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.