Strain Name:
C57BL/6J-MtgxR0375Btlr/Mmmh
Stock Number:
038581-MU
Citation ID:
RRID:MMRRC_038581-MU
Other Names:
R0375 (G1), C57BL/6J-MtgxR0375Btlr
Major Collection:

Gene Information

Zdhhc17
Name: zinc finger, DHHC domain containing 17
Synonyms: A230053P19Rik, D130071N24Rik, Hip14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 320150
VEGA: 10
Homologene: 56324
Gpr37
Name: G protein-coupled receptor 37
Synonyms: Pael-R, parkin-associated endothelin B-like receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14763
HGNC: HGNC:4494
Homologene: 3875
Vcan
Name: versican
Synonyms: PG-M, hdf, heart defect, 5430420N07Rik, DPEAAE, Cspg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Cacna1g
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms: a1G, Cav3.1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12291
HGNC: HGNC:1394
Homologene: 22544
Prrc1
Name: proline-rich coiled-coil 1
Synonyms: 2310058D16Rik, 9430085A19Rik, 3110038B19Rik, 1190002C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 73137
VEGA: 18
Homologene: 12491
Ylpm1
Name: YLP motif containing 1
Synonyms: ZAP, Zap3, A930013E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56531
Homologene: 87707
Cwc27
Name: CWC27 spliceosome-associated protein
Synonyms: NY-CO-10, 3110009E13Rik, Sdccag10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67285
Homologene: 21192
Ggnbp2
Name: gametogenetin binding protein 2
Synonyms: DIF-3, Zfp403, D330017P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217039
Homologene: 11750
Camk1g
Name: calcium/calmodulin-dependent protein kinase I gamma
Synonyms: CLICK-III, CaMKIgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 215303
Homologene: 48706
Dhx38
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 38
Synonyms: Prp16, Ddx38, 5730550P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 64340
Homologene: 8512
Ranbp2
Name: RAN binding protein 2
Synonyms: A430087B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19386
VEGA: 10
Homologene: 87808
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: Tweek, FSA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229227
Homologene: 52105
Tbck
Name: TBC1 domain containing kinase
Synonyms: A630047E20Rik, C030007I09Rik, 1700120J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 271981
Homologene: 13221
Marf1
Name: meiosis regulator and mRNA stability 1
Synonyms: 4921513D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 223989
VEGA: 16
Homologene: 40967
Adgrl1
Name: adhesion G protein-coupled receptor L1
Synonyms: Lec2, lectomedin-2, 2900070I05Rik, Lphn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330814
Homologene: 8951
Tasor2
Name: transcription activation suppressor family member 2
Synonyms: BC016423, Fam208b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105203
VEGA: 13
Homologene: 26435
Slc25a46
Name: solute carrier family 25, member 46
Synonyms: 1200007B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67453
VEGA: 18
Homologene: 14518
Dsg4
Name: desmoglein 4
Synonyms: lah, CDHF13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16769
Homologene: 65341
Ppp6r1
Name: protein phosphatase 6, regulatory subunit 1
Synonyms: 2010309P17Rik, B430201G11Rik, Pp6r1, Saps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243819
Homologene: 86982
Hoxd10
Name: homeobox D10
Synonyms: Hox-4.5, Hox-5.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15430
HGNC: HGNC:5133
Homologene: 1619
Cuzd1
Name: CUB and zona pellucida-like domains 1
Synonyms: UTCZP, UO-44, ERG-1, Itmap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16433
Homologene: 7389
Hbs1l
Name: Hbs1-like (S. cerevisiae)
Synonyms: eRFS, 2810035F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 56422
VEGA: 10
HGNC: HGNC:4834
Homologene: 68525
Snrnp27
Name: small nuclear ribonucleoprotein 27 (U4/U6.U5)
Synonyms: 2610209M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66618
Homologene: 135794
Sf3b2
Name: splicing factor 3b, subunit 2
Synonyms: SAP145, SF3b1, B230398H18Rik, 145kDa, SF3b150, SF3b145, 2810441F20Rik, 2610311M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 319322
VEGA: 19
Homologene: 6678
Rnf214
Name: ring finger protein 214
Synonyms: D130054N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235315
Homologene: 109357
Clic5
Name: chloride intracellular channel 5
Synonyms: 5730531E12Rik, nmf318
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224796
VEGA: 17
Homologene: 987
Dhx57
Name: DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106794
VEGA: 17
Homologene: 56267
Setd1b
Name: SET domain containing 1B
Synonyms: KMT2G
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 208043
Homologene: 134654
Vmn2r103
Name: vomeronasal 2, receptor 103
Synonyms: EG627636
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627636
Homologene: 115024
Aff3
Name: AF4/FMR2 family, member 3
Synonyms: LAF-4, 3222402O04Rik, Laf4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16764
HGNC: HGNC:6473
Homologene: 1718
Fbxw18
Name: F-box and WD-40 domain protein 18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 546161
Homologene: 110776
Col27a1
Name: collagen, type XXVII, alpha 1
Synonyms: 5730512J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 373864
Homologene: 69400
Col7a1
Name: collagen, type VII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12836
HGNC: HGNC:2214
Homologene: 73
Nckap1l
Name: NCK associated protein 1 like
Synonyms: 4930568P13Rik, Hem1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105855
VEGA: 15
HGNC: HGNC:4862
Homologene: 3901
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242627
Homologene: 135888
Abca9
Name: ATP-binding cassette, sub-family A (ABC1), member 9
Synonyms: D630040K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217262
HGNC: HGNC:39
Homologene: 33332
Naip1
Name: NLR family, apoptosis inhibitory protein 1
Synonyms: D13Lsd1, Naip, Birc1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17940
VEGA: 13
HGNC: HGNC:7634
Homologene: 113589
Myo1f
Name: myosin IF
Synonyms: C330006B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17916
HGNC: HGNC:7600
Homologene: 56276
AC104834.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Ror2
Name: receptor tyrosine kinase-like orphan receptor 2
Synonyms: Ntrkr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 26564
Homologene: 55831
Frmpd1
Name: FERM and PDZ domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 666060
Homologene: 8939
Dtx1
Name: deltex 1, E3 ubiquitin ligase
Synonyms: Fxit1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14357
HGNC: HGNC:3060
Homologene: 74522
Spag17
Name: sperm associated antigen 17
Synonyms: 4931427F14Rik, PF6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74362
Homologene: 52601
Pex16
Name: peroxisomal biogenesis factor 16
Synonyms: peroxisome biogenesis factor 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18633
HGNC: HGNC:8857
Homologene: 3537
F830016B08Rik
Name: RIKEN cDNA F830016B08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240328
VEGA: 18
Homologene: 129714
Tbc1d31
Name: TBC1 domain family, member 31
Synonyms: LOC210544, D330013L20Rik, Wdr67
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 210544
Homologene: 17089
Aars2
Name: alanyl-tRNA synthetase 2, mitochondrial
Synonyms: Aarsl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224805
VEGA: 17
Homologene: 56897
Cd46
Name: CD46 antigen, complement regulatory protein
Synonyms: CD46, Mcp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17221
HGNC: HGNC:6953
Homologene: 7832
Npm3
Name: nucleoplasmin 3
Synonyms: Nub1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18150
HGNC: HGNC:7931
Homologene: 5083
BC049715
Name: cDNA sequence BC049715
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320135
Homologene: 52193
Carf
Name: calcium response factor
Synonyms: Als2cr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241066
Homologene: 11689
Olfr248
Name: olfactory receptor 248
Synonyms: GA_x6K02T2MFC0-1145-1312, GA_x6K02T2P20D-20771141-20770212, MOR267-7, Olfr415
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258709
Olfr1200
Name: olfactory receptor 1200
Synonyms: GA_x6K02T2Q125-50243231-50242221, MOR225-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257887
Homologene: 123770
Olfr1240
Name: olfactory receptor 1240
Synonyms: GA_x6K02T2Q125-50883183-50882239, MOR231-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258804
Homologene: 121591
Ifnb1
Name: interferon beta 1, fibroblast
Synonyms: interferon beta 1, fibroblast, Ifb, IFNB, IFN-beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15977
HGNC: HGNC:5434
Homologene: 1640
Selplg
Name: selectin, platelet (p-selectin) ligand
Synonyms: Psgl-1, Psgl1, CD162
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20345
Homologene: 2261
Tas2r144
Name: taste receptor, type 2, member 144
Synonyms: mt2r33, Tas2r44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387515
Homologene: 47977
Vmn1r70
Name: vomeronasal 1 receptor 70
Synonyms: V1rl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171262
Homologene: 74361
AC162446.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
5730522E02Rik
Name: RIKEN cDNA 5730522E02 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70626
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 38,204,940 bp
  • T to C, chromosome 1 at 60,144,002 bp
  • A to G, chromosome 1 at 174,391,209 bp
  • G to A, chromosome 1 at 193,356,401 bp
  • A to G, chromosome 1 at 195,086,164 bp
  • C to A, chromosome 2 at 74,692,720 bp
  • T to A, chromosome 2 at 88,767,641 bp
  • G to T, chromosome 2 at 89,439,396 bp
  • G to A, chromosome 2 at 92,380,457 bp
  • C to T, chromosome 3 at 37,046,252 bp
  • C to A, chromosome 3 at 100,027,590 bp
  • C to A, chromosome 3 at 132,751,232 bp
  • A to G, chromosome 4 at 45,284,196 bp
  • A to G, chromosome 4 at 63,225,661 bp
  • A to T, chromosome 4 at 88,522,744 bp
  • A to G, chromosome 4 at 113,705,596 bp
  • G to A, chromosome 5 at 113,820,008 bp
  • T to C, chromosome 5 at 120,681,399 bp
  • G to A, chromosome 5 at 123,157,437 bp
  • T to C, chromosome 6 at 25,669,291 bp
  • T to A, chromosome 6 at 42,216,124 bp
  • A to T, chromosome 6 at 86,680,953 bp
  • A to T, chromosome 6 at 136,839,996 bp
  • A to G, chromosome 7 at 4,633,287 bp
  • T to A, chromosome 7 at 10,634,060 bp
  • G to A, chromosome 7 at 131,311,908 bp
  • A to G, chromosome 8 at 70,718,645 bp
  • G to T, chromosome 8 at 83,934,901 bp
  • A to G, chromosome 8 at 109,555,181 bp
  • C to A, chromosome 9 at 45,899,823 bp
  • C to T, chromosome 9 at 108,980,237 bp
  • T to C, chromosome 9 at 109,688,839 bp
  • T to A, chromosome 10 at 21,342,541 bp
  • T to C, chromosome 10 at 58,477,283 bp
  • A to T, chromosome 10 at 110,982,106 bp
  • T to A, chromosome 11 at 25,769,092 bp
  • G to T, chromosome 11 at 84,836,374 bp
  • C to A, chromosome 11 at 94,411,054 bp
  • A to T, chromosome 11 at 110,115,447 bp
  • T to G, chromosome 12 at 85,014,980 bp
  • A to G, chromosome 13 at 3,596,842 bp
  • T to C, chromosome 13 at 53,132,004 bp
  • A to G, chromosome 13 at 89,691,275 bp
  • A to G, chromosome 13 at 100,409,148 bp
  • T to C, chromosome 13 at 104,807,823 bp
  • T to A, chromosome 15 at 57,955,350 bp
  • G to A, chromosome 15 at 101,054,093 bp
  • A to G, chromosome 15 at 103,474,159 bp
  • T to C, chromosome 16 at 14,151,320 bp
  • T to A, chromosome 17 at 19,792,859 bp
  • A to G, chromosome 17 at 19,793,464 bp
  • T to A, chromosome 17 at 33,601,956 bp
  • A to G, chromosome 17 at 44,270,623 bp
  • A to G, chromosome 17 at 45,514,550 bp
  • T to G, chromosome 17 at 80,258,121 bp
  • A to G, chromosome 18 at 20,470,879 bp
  • T to C, chromosome 18 at 31,583,266 bp
  • A to G, chromosome 18 at 57,362,492 bp
  • A to T, chromosome 18 at 60,300,193 bp
  • C to T, chromosome 19 at 5,274,824 bp
  • T to C, chromosome 19 at 45,748,229 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0375 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038581-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.