Strain Name:
C57BL/6J-MtgxR0411Btlr/Mmmh
Stock Number:
038613-MU
Citation ID:
RRID:MMRRC_038613-MU
Other Names:
R0411 (G1), C57BL/6J-MtgxR0411Btlr
Major Collection:

Gene Information

Sulf2
Name: sulfatase 2
Synonyms: 2010004N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 72043
Homologene: 10313
Gga3
Name: golgi associated, gamma adaptin ear containing, ARF binding protein 3
Synonyms: C230037M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 260302
Homologene: 121703
Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231051
Homologene: 46480
Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Synonyms: Glyt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 104245
Homologene: 37901
Gria2
Name: glutamate receptor, ionotropic, AMPA2 (alpha 2)
Synonyms: Glur2, Glur-2, GluR2, GluA2, GluR-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 14800
HGNC: HGNC:4572
Homologene: 20225
Ncoa3
Name: nuclear receptor coactivator 3
Synonyms: TRAM-1, Src3, pCIP, KAT13B, bHLHe42, RAC3, 2010305B15Rik, AIB1, TRAM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17979
HGNC: HGNC:7670
Homologene: 4764
Iffo2
Name: intermediate filament family orphan 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 212632
Homologene: 102202
Olfm1
Name: olfactomedin 1
Synonyms: Noelin 1, Pancortin 1-4, Noelin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56177
Homologene: 8612
Ptcd2
Name: pentatricopeptide repeat domain 2
Synonyms: 1190005P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 68927
VEGA: 13
Homologene: 11695
Sik3
Name: SIK family kinase 3
Synonyms: 5730525O22Rik, 9030204A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 70661
Homologene: 57023
Naa15
Name: N(alpha)-acetyltransferase 15, NatA auxiliary subunit
Synonyms: Narg1, tubedown, mNAT1, ASTBDN, Tbdn-1, 5730450D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74838
Homologene: 14211
Plk4
Name: polo like kinase 4
Synonyms: Sak, Stk18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20873
Homologene: 7962
Arih1
Name: ariadne RBR E3 ubiquitin protein ligase 1
Synonyms: UIP77
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 23806
HGNC: HGNC:689
Homologene: 111871
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: Mll, Mll1, All1, HTRX1, ALL-1, trithorax Drosophila, Cxxc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Bmpr1a
Name: bone morphogenetic protein receptor, type 1A
Synonyms: 1110037I22Rik, ALK3, Bmpr, BMPR-IA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 12166
HGNC: HGNC:1076
Homologene: 20911
Setdb1
Name: SET domain, bifurcated 1
Synonyms: ESET, KMT1E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 84505
Homologene: 32157
Polr1a
Name: polymerase (RNA) I polypeptide A
Synonyms: RPA194, 194kDa, Rpo1-4, 2900087K15Rik, 3010014K16Rik, mRPA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 20019
Homologene: 7033
Acin1
Name: apoptotic chromatin condensation inducer 1
Synonyms: Acinus, 2610036I19Rik, 2610510L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 56215
Homologene: 22853
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Trf
Name: transferrin
Synonyms: Tfn, HP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22041
Homologene: 68153
Cd55
Name: CD55 molecule, decay accelerating factor for complement
Synonyms: Daf1, Cromer blood group, complement-glycosylphosphatidylinositol, GPI-DAF, Daf-GPI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13136
HGNC: HGNC:2665
Homologene: 479
Slc6a3
Name: solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Synonyms: DAT, Dat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13162
VEGA: 13
Homologene: 55547
Cacng3
Name: calcium channel, voltage-dependent, gamma subunit 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 54376
HGNC: HGNC:1407
Homologene: 4767
Ern1
Name: endoplasmic reticulum (ER) to nucleus signalling 1
Synonyms: Ire1p, Ire1a, 9030414B18Rik, Ire1alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 78943
HGNC: HGNC:3449
Homologene: 55580
Setd1a
Name: SET domain containing 1A
Synonyms: KMT2F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233904
Homologene: 52251
Izumo4
Name: IZUMO family member 4
Synonyms: 9030607L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71564
VEGA: 10
Homologene: 50465
Cenpe
Name: centromere protein E
Synonyms: CENP-E, 312kDa, Kif10, N-7 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Ddost
Name: dolichyl-di-phosphooligosaccharide-protein glycotransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13200
HGNC: HGNC:2728
Homologene: 3821
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, Odz3, 2610100B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 23965
Homologene: 22673
Appl1
Name: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Synonyms: 2900057D21Rik, 7330406P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 72993
Homologene: 32143
Pard6g
Name: par-6 family cell polarity regulator gamma
Synonyms: 2410049N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93737
VEGA: 18
Homologene: 36487
Pja2
Name: praja ring finger ubiquitin ligase 2
Synonyms: Neurodap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224938
Homologene: 32233
Smox
Name: spermine oxidase
Synonyms: B130066H01Rik, SMO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228608
Homologene: 69268
Aqp9
Name: aquaporin 9
Synonyms: 1700020I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 64008
HGNC: HGNC:643
Homologene: 41405
Myo7a
Name: myosin VIIA
Synonyms: USH1B, Hdb, Myo7, polka, nmf371
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17921
HGNC: HGNC:7606
Homologene: 219
Ropn1
Name: ropporin, rhophilin associated protein 1
Synonyms: RHPNAP1, ODF6, 1700008N21Rik, ropporin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 76378
Homologene: 57119
Hmbs
Name: hydroxymethylbilane synthase
Synonyms: Uros1, porphobilinogen deaminase, PBGD, Ups
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 15288
VEGA: 9
HGNC: HGNC:4982
Homologene: 158
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, Nesp2g, nesprin-2, syne-2, dice, Cpfl8, 6820443O06Rik, diminished cone electroretinogram
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319565
Homologene: 56700
Usp40
Name: ubiquitin specific peptidase 40
Synonyms: B230215L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227334
Homologene: 32400
Nfatc1
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
Synonyms: 2210017P03Rik, NF-ATc, NFATc, NFAT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 18018
VEGA: 18
HGNC: HGNC:7775
Homologene: 32336
Abcc12
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Synonyms: 4930467B22Rik, MRP9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244562
Homologene: 57211
Vmn2r19
Name: vomeronasal 2, receptor 19
Synonyms: EG232358
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232358
Homologene: 84037
Cacna1s
Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Synonyms: sj, DHPR alpha1s, muscle dysgenesis, fmd, Cchl1a3, mdg, Cav1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12292
HGNC: HGNC:1397
Homologene: 37257
Gm7271
Name: predicted gene 7271
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 639545
Ifi30
Name: interferon gamma inducible protein 30
Synonyms: lysosomal thio reductase IP30 precursor, GILT, IP30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 65972
VEGA: 8
HGNC: HGNC:5398
Homologene: 38171
Irf2
Name: interferon regulatory factor 2
Synonyms: 9830146E22Rik, Irf-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16363
HGNC: HGNC:6117
Homologene: 1659
Otoa
Name: otoancorin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 246190
Homologene: 71803
Slc36a1
Name: solute carrier family 36 (proton/amino acid symporter), member 1
Synonyms: 5830411H19Rik, Pat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 215335
Homologene: 121860
Cd101
Name: CD101 antigen
Synonyms: Igsf2, LOC381460
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 630146
HGNC: HGNC:5949
Homologene: 3142
Galntl5
Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
Synonyms: 1700021B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67909
Homologene: 12210
Wdr66
Name: WD repeat domain 66
Synonyms: 4930415N18Rik, 4933428F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 269701
Homologene: 16964
Tns1
Name: tensin 1
Synonyms: 1200014E20Rik, E030037J05Rik, 1110018I21Rik, Tns, E030018G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 21961
Homologene: 11219
Acad11
Name: acyl-Coenzyme A dehydrogenase family, member 11
Synonyms: 5730439E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102632
Homologene: 49896
Olfr1329
Name: olfactory receptor 1329
Synonyms: MOR259-2, GA_x6K02T2QD9B-18619941-18620882
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 258214
Homologene: 79401
Bmi1
Name: Bmi1 polycomb ring finger oncogene
Synonyms: Bmi1, Bmi-1, Pcgf4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12151
Homologene: 3797
0610040J01Rik
Name: RIKEN cDNA 0610040J01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 76261
Homologene: 49537
Vmn2r118
Name: vomeronasal 2, receptor 118
Synonyms: Vmn2r119, EG383258, EG668547
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 383258
Homologene: 129687
Zfp326
Name: zinc finger protein 326
Synonyms: ZAN75, 5730470H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54367
Homologene: 10297
Maip1
Name: matrix AAA peptidase interacting protein 1
Synonyms: 9430016H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68115
Homologene: 11565
Lyg1
Name: lysozyme G-like 1
Synonyms: 2300002O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 69541
Homologene: 18376
Klhdc9
Name: kelch domain containing 9
Synonyms: ESTM31, 1190002J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68874
Homologene: 66637
Olfr1118
Name: olfactory receptor 1118
Synonyms: Olfr1118-ps, MOR264-22, GA_x6K02T2Q125-48795705-48796673
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 404328
Homologene: 134077
Pax5
Name: paired box 5
Synonyms: Pax-5, EBB-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18507
HGNC: HGNC:8619
Homologene: 56419
Padi4
Name: peptidyl arginine deiminase, type IV
Synonyms: Pdi4, PAD type IV, Pad4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18602
Homologene: 7883
Ddx19b
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b
Synonyms: 2810457M08Rik, 4921519L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234733
HGNC: HGNC:2742
Homologene: 56032
Necab2
Name: N-terminal EF-hand calcium binding protein 2
Synonyms: Necab2, Efcbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 117148
Homologene: 62200
6030469F06Rik
Name: RIKEN cDNA 6030469F06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 100043065
VEGA: 12
Cma2
Name: chymase 2, mast cell
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 545055
VEGA: 14
Homologene: 115745
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 37,949,896 bp
  • T to G, chromosome 1 at 57,415,693 bp
  • A to T, chromosome 1 at 73,925,761 bp
  • T to C, chromosome 1 at 87,980,965 bp
  • A to G, chromosome 1 at 130,462,557 bp
  • A to G, chromosome 1 at 136,113,303 bp
  • A to G, chromosome 1 at 171,359,785 bp
  • T to C, chromosome 2 at 18,683,172 bp
  • G to A, chromosome 2 at 28,208,211 bp
  • A to G, chromosome 2 at 76,709,373 bp
  • A to G, chromosome 2 at 87,309,058 bp
  • G to T, chromosome 2 at 131,520,644 bp
  • A to G, chromosome 2 at 166,068,543 bp
  • G to T, chromosome 2 at 166,093,516 bp
  • T to A, chromosome 3 at 40,811,219 bp
  • T to A, chromosome 3 at 51,465,639 bp
  • C to T, chromosome 3 at 80,710,858 bp
  • T to C, chromosome 3 at 95,327,686 bp
  • A to T, chromosome 3 at 101,018,527 bp
  • T to C, chromosome 3 at 135,222,255 bp
  • A to G, chromosome 4 at 44,609,783 bp
  • A to T, chromosome 4 at 118,916,626 bp
  • T to A, chromosome 4 at 138,309,653 bp
  • A to G, chromosome 4 at 139,603,221 bp
  • GCTGCGTACCTCCAC to GC, chromosome 4 at 140,748,449 bp
  • C to T, chromosome 5 at 25,220,174 bp
  • A to T, chromosome 5 at 25,375,957 bp
  • A to G, chromosome 5 at 63,896,491 bp
  • G to T, chromosome 5 at 76,500,487 bp
  • G to T, chromosome 5 at 105,878,775 bp
  • C to T, chromosome 5 at 123,290,054 bp
  • A to T, chromosome 6 at 71,978,421 bp
  • A to G, chromosome 6 at 123,309,744 bp
  • A to T, chromosome 7 at 49,911,791 bp
  • T to C, chromosome 7 at 98,071,937 bp
  • T to C, chromosome 7 at 121,156,527 bp
  • C to T, chromosome 7 at 122,768,572 bp
  • T to C, chromosome 7 at 127,796,051 bp
  • T to A, chromosome 8 at 46,846,061 bp
  • C to T, chromosome 8 at 48,287,791 bp
  • A to G, chromosome 8 at 70,764,918 bp
  • A to G, chromosome 8 at 86,531,626 bp
  • A to T, chromosome 8 at 111,023,964 bp
  • T to A, chromosome 8 at 119,454,240 bp
  • A to T, chromosome 9 at 44,341,652 bp
  • T to C, chromosome 9 at 44,819,964 bp
  • T to A, chromosome 9 at 46,208,770 bp
  • A to G, chromosome 9 at 54,378,939 bp
  • A to T, chromosome 9 at 59,485,983 bp
  • C to A, chromosome 9 at 71,130,444 bp
  • C to T, chromosome 9 at 103,217,501 bp
  • T to C, chromosome 9 at 104,116,296 bp
  • T to C, chromosome 10 at 80,703,084 bp
  • G to T, chromosome 11 at 55,232,507 bp
  • C to T, chromosome 11 at 106,398,586 bp
  • A to G, chromosome 11 at 115,587,433 bp
  • A to T, chromosome 12 at 31,184,731 bp
  • C to T, chromosome 12 at 76,059,584 bp
  • T to C, chromosome 13 at 73,557,050 bp
  • G to A, chromosome 13 at 99,343,391 bp
  • A to G, chromosome 14 at 26,940,256 bp
  • G to A, chromosome 14 at 34,415,877 bp
  • G to T, chromosome 14 at 54,646,774 bp
  • A to G, chromosome 14 at 55,973,678 bp
  • T to A, chromosome 16 at 34,669,964 bp
  • A to G, chromosome 17 at 55,611,021 bp
  • A to T, chromosome 17 at 64,287,521 bp
  • A to G, chromosome 18 at 80,117,122 bp
  • T to A, chromosome 18 at 80,698,042 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0411 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038613-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.