Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR0417Btlr/Mmmh
Stock Number:
038619-MU
Citation ID:
RRID:MMRRC_038619-MU
Other Names:
R0417 (G1), C57BL/6J-MtgxR0417Btlr
Major Collection:

Strain Information

Fzd9
Name: frizzled class receptor 9
Synonyms: mfz9, frizzled 9, Fz9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14371
HGNC: HGNC:4047
Homologene: 2619
Mga
Name: MAX gene associated
Synonyms: Mga, Mad5, C130042M01Rik, D030062C11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 29808
Homologene: 49351
Csrnp3
Name: cysteine-serine-rich nuclear protein 3
Synonyms: mbu1, A330102K23Rik, CSRNP-3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77771
Homologene: 11803
Cbln3
Name: cerebellin 3 precursor protein
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56410
VEGA: 14
Homologene: 56861
Snapc3
Name: small nuclear RNA activating complex, polypeptide 3
Synonyms: 5031401C21Rik, 4930558A07Rik, 1810020H02Rik, E030018J20Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77634
Homologene: 31130
Ezh2
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Synonyms: Enx-1, Enx1h, KMT6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14056
HGNC: HGNC:3527
Homologene: 37926
Tut7
Name: terminal uridylyl transferase 7
Synonyms: 6030448M23Rik, Tent3b, Zcchc6
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 214290
VEGA: 13
Homologene: 51941
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 45,911,374 bp
  • T to C, chromosome 1 at 60,247,734 bp
  • A to T, chromosome 1 at 133,658,538 bp
  • A to G, chromosome 1 at 179,755,662 bp
  • A to T, chromosome 1 at 191,011,219 bp
  • C to A, chromosome 2 at 35,321,632 bp
  • A to G, chromosome 2 at 66,019,543 bp
  • G to A, chromosome 2 at 72,971,501 bp
  • A to T, chromosome 2 at 87,033,445 bp
  • C to A, chromosome 2 at 89,440,175 bp
  • A to T, chromosome 2 at 90,735,427 bp
  • A to G, chromosome 2 at 111,369,105 bp
  • A to G, chromosome 2 at 112,794,607 bp
  • A to G, chromosome 2 at 119,902,790 bp
  • A to G, chromosome 2 at 127,186,944 bp
  • C to A, chromosome 2 at 167,457,344 bp
  • T to A, chromosome 3 at 7,576,027 bp
  • T to A, chromosome 3 at 18,096,691 bp
  • T to C, chromosome 3 at 38,456,361 bp
  • T to C, chromosome 3 at 86,715,654 bp
  • T to A, chromosome 3 at 100,065,554 bp
  • T to C, chromosome 3 at 116,024,357 bp
  • A to G, chromosome 3 at 139,218,321 bp
  • A to G, chromosome 4 at 83,450,162 bp
  • A to T, chromosome 4 at 100,412,000 bp
  • A to G, chromosome 4 at 119,170,496 bp
  • T to A, chromosome 4 at 120,922,072 bp
  • T to A, chromosome 4 at 133,248,082 bp
  • A to G, chromosome 4 at 144,976,560 bp
  • T to C, chromosome 4 at 152,015,507 bp
  • A to G, chromosome 4 at 154,267,967 bp
  • T to A, chromosome 5 at 14,713,022 bp
  • T to A, chromosome 5 at 87,777,438 bp
  • G to T, chromosome 5 at 96,691,372 bp
  • G to T, chromosome 5 at 135,249,619 bp
  • A to G, chromosome 6 at 47,551,726 bp
  • C to T, chromosome 6 at 50,348,018 bp
  • A to T, chromosome 6 at 83,031,569 bp
  • A to T, chromosome 7 at 3,304,304 bp
  • A to G, chromosome 7 at 4,151,483 bp
  • C to A, chromosome 7 at 15,972,322 bp
  • A to T, chromosome 7 at 46,068,698 bp
  • A to T, chromosome 7 at 89,971,552 bp
  • T to C, chromosome 8 at 3,388,957 bp
  • A to G, chromosome 8 at 72,445,400 bp
  • T to C, chromosome 8 at 121,886,843 bp
  • A to G, chromosome 9 at 3,759,484 bp
  • T to A, chromosome 9 at 7,276,602 bp
  • T to C, chromosome 9 at 9,180,033 bp
  • G to A, chromosome 9 at 20,171,214 bp
  • A to G, chromosome 9 at 38,219,455 bp
  • T to C, chromosome 9 at 38,253,864 bp
  • A to T, chromosome 9 at 107,543,298 bp
  • T to C, chromosome 9 at 120,557,421 bp
  • C to T, chromosome 9 at 121,788,762 bp
  • A to G, chromosome 10 at 8,245,936 bp
  • A to T, chromosome 10 at 18,603,511 bp
  • A to T, chromosome 10 at 61,180,339 bp
  • A to T, chromosome 10 at 81,530,904 bp
  • A to C, chromosome 11 at 11,769,352 bp
  • A to G, chromosome 11 at 49,175,595 bp
  • T to A, chromosome 11 at 49,340,673 bp
  • C to T, chromosome 11 at 55,181,544 bp
  • C to T, chromosome 11 at 70,321,865 bp
  • T to C, chromosome 11 at 87,875,328 bp
  • T to C, chromosome 12 at 32,833,101 bp
  • G to A, chromosome 12 at 44,902,957 bp
  • T to C, chromosome 12 at 83,990,613 bp
  • A to C, chromosome 12 at 111,426,011 bp
  • C to T, chromosome 13 at 38,221,405 bp
  • C to T, chromosome 13 at 55,474,916 bp
  • A to G, chromosome 13 at 59,814,968 bp
  • T to C, chromosome 14 at 32,326,979 bp
  • C to T, chromosome 14 at 52,296,698 bp
  • T to G, chromosome 14 at 55,884,129 bp
  • A to C, chromosome 15 at 58,921,350 bp
  • A to T, chromosome 15 at 82,455,951 bp
  • A to G, chromosome 15 at 97,691,318 bp
  • T to C, chromosome 16 at 44,520,234 bp
  • A to G, chromosome 16 at 57,149,903 bp
  • G to A, chromosome 16 at 96,162,653 bp
  • T to C, chromosome 17 at 50,756,705 bp
  • A to T, chromosome 18 at 82,405,540 bp
  • A to G, chromosome 19 at 4,737,926 bp
  • A to G, chromosome 19 at 12,711,060 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0417 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038619-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.