Strain Name:
C57BL/6J-MtgxR0457Btlr/Mmmh
Stock Number:
038657-MU
Citation ID:
RRID:MMRRC_038657-MU
Other Names:
R0457 (G1), C57BL/6J-MtgxR0457Btlr
Major Collection:

Gene Information

Vcan
Name: versican
Synonyms: heart defect, Cspg2, PG-M, hdf, 5430420N07Rik, DPEAAE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Ntrk1
Name: neurotrophic tyrosine kinase, receptor, type 1
Synonyms: TrkA, Tkr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18211
HGNC: HGNC:8031
Homologene: 1898
Mga
Name: MAX gene associated
Synonyms: Mad5, Mga, C130042M01Rik, D030062C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 29808
Homologene: 49351
Phf12
Name: PHD finger protein 12
Synonyms: 2410142K10Rik, PF1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268448
Homologene: 10841
Dock1
Name: dedicator of cytokinesis 1
Synonyms: D630004B07Rik, 9130006G06Rik, b2b3190Clo, Dock180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330662
HGNC: HGNC:2987
Homologene: 55575
Hsp90ab1
Name: heat shock protein 90 alpha (cytosolic), class B member 1
Synonyms: Hsp90, C81438, Hspcb, Hsp84, Hsp84-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15516
HGNC: HGNC:5258
Homologene: 74306
Wnk1
Name: WNK lysine deficient protein kinase 1
Synonyms: 6430573H23Rik, EG406236, Hsn2, Prkwnk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232341
Homologene: 14253
Dyrk3
Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226419
HGNC: HGNC:3094
Homologene: 55762
Mark2
Name: MAP/microtubule affinity regulating kinase 2
Synonyms: Par-1, Emk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 13728
HGNC: HGNC:3332
Homologene: 69013
Atp2a2
Name: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Synonyms: Serca2a, sarco/endoplasmic reticulum Ca2+-ATPase 2, SERCA2, 9530097L16Rik, D5Wsu150e, SERCA2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11938
HGNC: HGNC:812
Homologene: 80167
Polr1c
Name: polymerase (RNA) I polypeptide C
Synonyms: Rpo1-1, 40kDa, RPA40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20016
Homologene: 3586
Kat6b
Name: K(lysine) acetyltransferase 6B
Synonyms: Morf, monocytic leukemia, B130044K16Rik, Myst4, querkopf, qkf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 54169
Homologene: 136480
Aspscr1
Name: alveolar soft part sarcoma chromosome region, candidate 1 (human)
Synonyms: ASPC, TUG, ASPCR1, RCC17, 1190006K01Rik, ASPL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68938
Homologene: 41550
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, A430032G04Rik, A430040A19Rik, D630005A10Rik, Bruce
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Ptpn23
Name: protein tyrosine phosphatase, non-receptor type 23
Synonyms: PTP-TD14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 104831
Homologene: 135706
Kpna1
Name: karyopherin (importin) alpha 1
Synonyms: mSRP1, Rch2, importin alpha 5, NPI1, m-importin-alpha-S1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16646
HGNC: HGNC:6394
Homologene: 55642
Ap1g1
Name: adaptor protein complex AP-1, gamma 1 subunit
Synonyms: gamma-adaptin, D8Ertd374e, Adtg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11765
HGNC: HGNC:555
Homologene: 47995
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: C130039F11Rik, enaptin165, SYNE-1, A330049M09Rik, nesprin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
St7
Name: suppression of tumorigenicity 7
Synonyms: TSG7, 9430001H04Rik, Fam4a2, HELG, RAY1, SEN4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 64213
Homologene: 10185
Fcho1
Name: FCH domain only 1
Synonyms: 3322402E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74015
Homologene: 22869
Dnajc10
Name: DnaJ heat shock protein family (Hsp40) member C10
Synonyms: JPDI, 1200006L06Rik, D2Ertd706e, ERdj5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66861
Homologene: 10358
Mcm9
Name: minichromosome maintenance 9 homologous recombination repair factor
Synonyms: Mcmdc1, 9030408O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71567
VEGA: 10
Homologene: 13546
Ganab
Name: alpha glucosidase 2 alpha neutral subunit
Synonyms: G2an, GluII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14376
VEGA: 19
HGNC: HGNC:4138
Homologene: 5426
Zfp37
Name: zinc finger protein 37
Synonyms: Zfp-37, Tzn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22696
Homologene: 40682
Msh3
Name: mutS homolog 3
Synonyms: D13Em1, Rep-3, Rep3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17686
HGNC: HGNC:7326
Homologene: 1829
Sptbn2
Name: spectrin beta, non-erythrocytic 2
Synonyms: Spnb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20743
VEGA: 19
Homologene: 48482
Bub1b
Name: BUB1B, mitotic checkpoint serine/threonine kinase
Synonyms: BUBR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12236
HGNC: HGNC:1149
Homologene: 933
Lrrc40
Name: leucine rich repeat containing 40
Synonyms: 2610040E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67144
Homologene: 9825
Trhde
Name: TRH-degrading enzyme
Synonyms: 9330155P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237553
Homologene: 75007
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Mthfd2l
Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
Synonyms: 1110019K23Rik, C630010D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 665563
Homologene: 28295
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 665700
Homologene: 90772
Ttn
Name: titin
Synonyms: mdm, 2310036G12Rik, D830007G01Rik, shru, L56, 2310074I15Rik, 2310057K23Rik, connectin, D330041I19Rik, 1100001C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Cmya5
Name: cardiomyopathy associated 5
Synonyms: 2310076E21Rik, 2310076E16Rik, Myospryn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 4833413O10Rik, 1110021D17Rik, Polydom, D430029O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 64817
Homologene: 23386
F5
Name: coagulation factor V
Synonyms: Cf5, Cf-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Col27a1
Name: collagen, type XXVII, alpha 1
Synonyms: 5730512J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 373864
Homologene: 69400
Fer1l6
Name: fer-1-like 6 (C. elegans)
Synonyms: EG631797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 631797
Homologene: 53396
Gbp5
Name: guanylate binding protein 5
Synonyms: 5330409J06Rik, Gbp5a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229898
Homologene: 14183
Slc7a1
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
Synonyms: Atrc1, 4831426K01Rik, Cat1, Rec-1, Rev-1, Atrc-1, mCAT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11987
Homologene: 20658
Cryga
Name: crystallin, gamma A
Synonyms: Secc, DGcry-4, Cryg-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12964
HGNC: HGNC:2408
Homologene: 129704
Chdh
Name: choline dehydrogenase
Synonyms: D630034H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218865
Homologene: 41261
Slc4a9
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 9
Synonyms: AE4, D630024F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240215
VEGA: 18
Homologene: 23732
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22635
Homologene: 124417
Adcy5
Name: adenylate cyclase 5
Synonyms: AC5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224129
VEGA: 16
HGNC: HGNC:236
Homologene: 11213
Unc13a
Name: unc-13 homolog A
Synonyms: 2410078G03Rik, Munc13-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382018
Homologene: 11279
Gne
Name: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Synonyms: 2310066H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 50798
Homologene: 3996
Synpo2
Name: synaptopodin 2
Synonyms: Myo, myopodin, 9530006G20Rik, 2310068J10Rik, 1110069I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 118449
Homologene: 15400
Olfr347
Name: olfactory receptor 347
Synonyms: MOR136-9, GA_x6K02T2NLDC-33428755-33429693
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258945
Homologene: 51790
Aadacl2fm1
Name: AADACL2 family member 1
Synonyms: C130079G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229333
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17836
Homologene: 136663
Wdr90
Name: WD repeat domain 90
Synonyms: 3230401M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106618
Homologene: 27066
Zfp521
Name: zinc finger protein 521
Synonyms: Evi3, B930086A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225207
VEGA: 18
Homologene: 9151
Pld2
Name: phospholipase D2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18806
HGNC: HGNC:9068
Homologene: 55672
Hapln4
Name: hyaluronan and proteoglycan link protein 4
Synonyms: Bral2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330790
Homologene: 11304
Ablim3
Name: actin binding LIM protein family, member 3
Synonyms: D930036B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 319713
VEGA: 18
Homologene: 69175
Cacna2d1
Name: calcium channel, voltage-dependent, alpha2/delta subunit 1
Synonyms: Cacna2, Ca(v)alpha2delta1, Cchl2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12293
HGNC: HGNC:1399
Homologene: 579
Phgdh
Name: 3-phosphoglycerate dehydrogenase
Synonyms: PGDH, 3PGDH, 3-PGDH, A10, PGAD, SERA, PGD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 236539
HGNC: HGNC:8923
Homologene: 39318
Vmn2r-ps129
Name: vomeronasal 2, receptor, pseudogene 129
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 665976
Vmn1r60
Name: vomeronasal 1 receptor 60
Synonyms: Gm7184
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 636697
Homologene: 41799
Fndc7
Name: fibronectin type III domain containing 7
Synonyms: E230011A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 320181
Homologene: 18551
Prob1
Name: proline rich basic protein 1
Synonyms: LOC381148, Gm1614
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 381148
Homologene: 83773
Myom3
Name: myomesin family, member 3
Synonyms: 8430427K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242702
Homologene: 19432
Ltv1
Name: LTV1 ribosome biogenesis factor
Synonyms: 2610020N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 353258
VEGA: 10
Homologene: 6338
C1ra
Name: complement component 1, r subcomponent A
Synonyms: mC1rA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 50909
HGNC: HGNC:1246
Homologene: 1313
Prkd1
Name: protein kinase D1
Synonyms: Pkcm, PKD1, Prkcm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18760
VEGA: 12
HGNC: HGNC:9407
Homologene: 55680
Ajm1
Name: apical junction component 1
Synonyms: LOC381353, Gm996
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381353
Homologene: 19943
Rnf11
Name: ring finger protein 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 29864
Homologene: 32195
Gtpbp6
Name: GTP binding protein 6 (putative)
Synonyms: pgpl, Pgbpll
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 107999
Homologene: 8157
Vmn1r29
Name: vomeronasal 1 receptor 29
Synonyms: V1rc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113859
Homologene: 123821
Crbn
Name: cereblon
Synonyms: 2900045O07Rik, 2610203G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 58799
Homologene: 9461
Scgb2b7
Name: secretoglobin, family 2B, member 7
Synonyms: Gm4684, Abpbg7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043836
Homologene: 83171
Olfr667
Name: olfactory receptor 667
Synonyms: GA_x6K02T2PBJ9-7546146-7545166, MOR34-2, MOR34-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259062
Homologene: 121559
Defa-ps1
Name: defensin, alpha, pseudogene 1
Synonyms: Defcr-ps26, Defcr-ps1, Crypi
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 727720
Gm17324
Name: predicted gene, 17324
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Rab40b
Name: Rab40B, member RAS oncogene family
Synonyms: rar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217371
Homologene: 4968
Dpf3
Name: D4, zinc and double PHD fingers, family 3
Synonyms: CERD4, cer-d4, 2810403B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 70127
Homologene: 129842
Ngb
Name: neuroglobin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 64242
Homologene: 10942
Lrrc14b
Name: leucine rich repeat containing 14B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 432779
Homologene: 47758
Fam186b
Name: family with sequence similarity 186, member B
Synonyms: EG545136
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 545136
VEGA: 15
Homologene: 69502
Sbp
Name: spermine binding protein
Synonyms: p25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20234
Homologene: 117464
Spire1
Name: spire type actin nucleation factor 1
Synonyms: Spir-1, 6030430B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68166
VEGA: 18
Homologene: 35507
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 65,103,045 bp
  • A to T, chromosome 1 at 131,136,357 bp
  • T to C, chromosome 1 at 164,194,200 bp
  • G to T, chromosome 2 at 25,578,346 bp
  • T to A, chromosome 2 at 31,415,284 bp
  • A to T, chromosome 2 at 36,734,533 bp
  • T to A, chromosome 2 at 76,778,507 bp
  • T to A, chromosome 2 at 80,344,946 bp
  • T to C, chromosome 2 at 118,609,859 bp
  • T to A, chromosome 2 at 119,916,488 bp
  • A to G, chromosome 3 at 59,936,633 bp
  • A to G, chromosome 3 at 87,791,707 bp
  • G to A, chromosome 3 at 98,319,606 bp
  • G to T, chromosome 3 at 108,876,545 bp
  • A to G, chromosome 3 at 123,112,772 bp
  • A to G, chromosome 3 at 142,507,757 bp
  • A to G, chromosome 3 at 158,054,564 bp
  • T to C, chromosome 4 at 44,041,649 bp
  • C to T, chromosome 4 at 58,118,136 bp
  • A to T, chromosome 4 at 62,191,665 bp
  • G to A, chromosome 4 at 63,318,254 bp
  • A to T, chromosome 4 at 109,456,952 bp
  • T to C, chromosome 4 at 135,801,791 bp
  • A to G, chromosome 5 at 16,267,416 bp
  • T to C, chromosome 5 at 91,020,206 bp
  • T to A, chromosome 5 at 110,106,742 bp
  • T to C, chromosome 5 at 122,469,714 bp
  • C to T, chromosome 5 at 137,407,706 bp
  • A to G, chromosome 5 at 148,342,859 bp
  • T to C, chromosome 6 at 17,819,282 bp
  • T to C, chromosome 6 at 58,308,087 bp
  • T to C, chromosome 6 at 106,781,057 bp
  • G to A, chromosome 6 at 119,969,332 bp
  • G to A, chromosome 6 at 121,861,555 bp
  • T to C, chromosome 6 at 124,522,753 bp
  • T to A, chromosome 7 at 5,545,119 bp
  • A to T, chromosome 7 at 31,704,012 bp
  • T to A, chromosome 7 at 104,916,973 bp
  • A to T, chromosome 7 at 135,138,145 bp
  • C to A, chromosome 8 at 16,501,393 bp
  • A to T, chromosome 8 at 21,695,742 bp
  • G to A, chromosome 8 at 70,088,472 bp
  • A to C, chromosome 8 at 71,658,001 bp
  • C to T, chromosome 8 at 71,712,560 bp
  • T to A, chromosome 8 at 109,851,032 bp
  • T to A, chromosome 9 at 78,448,298 bp
  • T to A, chromosome 9 at 110,386,293 bp
  • A to T, chromosome 10 at 5,022,041 bp
  • T to C, chromosome 10 at 13,192,143 bp
  • T to C, chromosome 10 at 53,611,341 bp
  • A to T, chromosome 10 at 114,448,262 bp
  • T to C, chromosome 11 at 70,541,990 bp
  • T to A, chromosome 11 at 78,018,168 bp
  • A to G, chromosome 11 at 120,677,618 bp
  • A to G, chromosome 11 at 121,357,322 bp
  • A to T, chromosome 12 at 50,366,372 bp
  • A to T, chromosome 12 at 83,272,405 bp
  • T to C, chromosome 12 at 87,100,729 bp
  • A to G, chromosome 13 at 74,361,160 bp
  • T to C, chromosome 13 at 89,703,199 bp
  • A to T, chromosome 13 at 92,220,997 bp
  • A to G, chromosome 13 at 93,095,587 bp
  • C to A, chromosome 14 at 21,670,530 bp
  • C to T, chromosome 14 at 30,036,466 bp
  • G to A, chromosome 15 at 58,638,094 bp
  • A to G, chromosome 15 at 76,177,601 bp
  • A to C, chromosome 15 at 99,271,285 bp
  • T to C, chromosome 16 at 35,274,545 bp
  • T to A, chromosome 16 at 36,002,905 bp
  • T to C, chromosome 17 at 23,008,363 bp
  • G to A, chromosome 17 at 23,945,312 bp
  • C to T, chromosome 17 at 25,860,485 bp
  • A to G, chromosome 17 at 45,568,988 bp
  • T to A, chromosome 17 at 46,247,763 bp
  • A to G, chromosome 17 at 74,652,028 bp
  • C to T, chromosome 17 at 74,662,625 bp
  • T to C, chromosome 18 at 13,844,840 bp
  • T to C, chromosome 18 at 35,652,486 bp
  • T to C, chromosome 18 at 36,535,418 bp
  • T to C, chromosome 18 at 61,820,364 bp
  • T to A, chromosome 18 at 67,552,600 bp
  • T to C, chromosome 19 at 4,745,938 bp
  • C to T, chromosome 19 at 7,286,996 bp
  • A to G, chromosome 19 at 8,907,250 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0457 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038657-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.