Strain Name:
C57BL/6J-MtgxR0467Btlr/Mmmh
Stock Number:
038667-MU
Citation ID:
RRID:MMRRC_038667-MU
Other Names:
R0467 (G1), C57BL/6J-MtgxR0467Btlr
Major Collection:

Gene Information

Ippk
Name: inositol 1,3,4,5,6-pentakisphosphate 2-kinase
Synonyms: 1810043M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75678
VEGA: 13
Homologene: 41495
Xrn1
Name: 5'-3' exoribonuclease 1
Synonyms: Dhm2, mXrn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 24127
Homologene: 5894
Atf6
Name: activating transcription factor 6
Synonyms: ESTM49, 9130025P16Rik, Atf6alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226641
HGNC: HGNC:791
Homologene: 32015
Mcm3
Name: minichromosome maintenance complex component 3
Synonyms: p1.m, P1, Mcmd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17215
HGNC: HGNC:6945
Homologene: 1791
Cul3
Name: cullin 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26554
HGNC: HGNC:2553
Homologene: 2661
Sulf1
Name: sulfatase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240725
Homologene: 49408
Nomo1
Name: nodal modulator 1
Synonyms: PM5, D7Ertd156e, Nomo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 211548
Homologene: 13810
G3bp1
Name: GTPase activating protein (SH3 domain) binding protein 1
Synonyms: GAP SH3 binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27041
Homologene: 38096
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: tsg24, Mcpr, Apc1, 2610021O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17222
Homologene: 7414
Ubxn4
Name: UBX domain protein 4
Synonyms: Ubxd2, 1300013G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67812
Homologene: 40962
Sgk1
Name: serum/glucocorticoid regulated kinase 1
Synonyms: Sgk, Sgk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20393
Homologene: 48364
Gcfc2
Name: GC-rich sequence DNA binding factor 2
Synonyms: AW146020
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330361
HGNC: HGNC:1317
Homologene: 2411
Rassf3
Name: Ras association (RalGDS/AF-6) domain family member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 192678
VEGA: 10
Homologene: 16365
Pgr
Name: progesterone receptor
Synonyms: PR-B, ENSMUSG00000074510, PR-A, NR3C3, PR, 9930019P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18667
HGNC: HGNC:8910
Homologene: 713
Abca17
Name: ATP-binding cassette, sub-family A (ABC1), member 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 381072
Homologene: 86807
Zfp408
Name: zinc finger protein 408
Synonyms: LOC381410
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381410
Homologene: 11687
Arhgdib
Name: Rho, GDP dissociation inhibitor (GDI) beta
Synonyms: D4, Gdid4, Ly-GDI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11857
HGNC: HGNC:679
Homologene: 20318
Cdk12
Name: cyclin-dependent kinase 12
Synonyms: 1810022J16Rik, Crkrs, Crk7, D11Ertd752e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69131
Homologene: 128632
Pdgfra
Name: platelet derived growth factor receptor, alpha polypeptide
Synonyms: Pdgfr-2, CD140a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18595
HGNC: HGNC:8803
Homologene: 31361
Ncoa1
Name: nuclear receptor coactivator 1
Synonyms: bHLHe74, steroid receptor coactivator-1, SRC1, KAT13A, SRC-a/NCoA-1, SRC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 17977
VEGA: 12
HGNC: HGNC:7668
Homologene: 7859
Pkd1l3
Name: polycystic kidney disease 1 like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244646
Homologene: 14627
Dnase1
Name: deoxyribonuclease I
Synonyms: DNaseI, Dnl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13419
HGNC: HGNC:2956
Homologene: 3826
Ltbp1
Name: latent transforming growth factor beta binding protein 1
Synonyms: LTBP-1, Ltbp1L, b2b1000Clo, 9430031G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268977
HGNC: HGNC:6714
Homologene: 522
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip2, Naip-rs6, Birc1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Nckap1l
Name: NCK associated protein 1 like
Synonyms: Hem1, 4930568P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105855
VEGA: 15
HGNC: HGNC:4862
Homologene: 3901
Mab21l4
Name: mab-21-like 4
Synonyms: 2310007B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71874
Homologene: 11761
Nalcn
Name: sodium leak channel, non-selective
Synonyms: Vgcnl1, A530023G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 338370
VEGA: 14
Homologene: 21832
Rsc1a1
Name: regulatory solute carrier protein, family 1, member 1
Synonyms: RS1, OTTMUSG00000010365, mRS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69994
Homologene: 130554
1700022I11Rik
Name: RIKEN cDNA 1700022I11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67317
Homologene: 52406
Iba57
Name: IBA57 homolog, iron-sulfur cluster assembly
Synonyms: A230051G13Rik, 4930543L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216792
Homologene: 13844
C4b
Name: complement component 4B (Chido blood group)
Synonyms: C4, Ss
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12268
Homologene: 36030
Gm5155
Name: predicted gene 5155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381852
Homologene: 115938
Pcdhb14
Name: protocadherin beta 14
Synonyms: 2210006M07Rik, Pcdhb17, PcdhbN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93885
Homologene: 70876
Galc
Name: galactosylceramidase
Synonyms: 2310068B06Rik, A930008M05Rik, galactocerebrosidase, Gacy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14420
VEGA: 12
HGNC: HGNC:4115
Homologene: 124
Cdh26
Name: cadherin-like 26
Synonyms: LOC381409
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381409
Homologene: 18643
Rgs22
Name: regulator of G-protein signalling 22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 626596
Homologene: 75047
Ipo4
Name: importin 4
Synonyms: 8430408O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 75751
Homologene: 5835
Olfr701
Name: olfactory receptor 701
Synonyms: 4933433E02Rik, 4932441H21Rik, GA_x6K02T2PBJ9-9195805-9196755, MOR283-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66786
Homologene: 12558
Klk14
Name: kallikrein related-peptidase 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 317653
HGNC: HGNC:6362
Homologene: 69348
Obox5
Name: oocyte specific homeobox 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 252829
Homologene: 44937
4933416C03Rik
Name: RIKEN cDNA 4933416C03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Dnaaf1
Name: dynein, axonemal assembly factor 1
Synonyms: 4930457P18Rik, m4Bei, Lrrc50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 68270
Homologene: 12256
Olfr76
Name: olfactory receptor 76
Synonyms: MOR215-3, GA_x6K02T2RE5P-2479601-2478648, V5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258677
HGNC: HGNC:8319
Homologene: 17342
Rsph6a
Name: radial spoke head 6 homolog A (Chlamydomonas)
Synonyms: RSP4, Rshl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 83434
Homologene: 36476
Fam71f1
Name: family with sequence similarity 71, member F1
Synonyms: LOC330277
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330277
Homologene: 13077
Shcbp1l
Name: Shc SH2-domain binding protein 1-like
Synonyms: 1700012A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71836
Homologene: 12800
Potegl
Name: POTE ankyrin domain family, member G like
Synonyms: 4931423N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70981
Homologene: 86765
Tas2r115
Name: taste receptor, type 2, member 115
Synonyms: Tas2r15, mt2r49, mGR15, T2R15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 353325
Olfr644
Name: olfactory receptor 644
Synonyms: MOR13-1, GA_x6K02T2PBJ9-6803062-6802118
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259125
Homologene: 17491
Tmem200a
Name: transmembrane protein 200A
Synonyms: C030003D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77220
VEGA: 10
Homologene: 14175
Kcnk10
Name: potassium channel, subfamily K, member 10
Synonyms: 1700024D23Rik, 3010005K24Rik, Trek2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 72258
VEGA: 12
HGNC: HGNC:6273
Homologene: 11321
Gm6133
Name: predicted gene 6133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 620155
VEGA: 18
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 12,796,920 bp
  • T to C, chromosome 1 at 20,804,847 bp
  • A to T, chromosome 1 at 80,280,863 bp
  • A to T, chromosome 1 at 93,153,044 bp
  • G to A, chromosome 1 at 128,262,904 bp
  • G to A, chromosome 1 at 153,433,182 bp
  • A to T, chromosome 1 at 170,794,020 bp
  • A to G, chromosome 2 at 23,212,820 bp
  • T to C, chromosome 2 at 91,645,537 bp
  • A to G, chromosome 2 at 128,669,043 bp
  • C to T, chromosome 2 at 178,481,632 bp
  • T to C, chromosome 4 at 42,972,715 bp
  • A to G, chromosome 4 at 141,685,184 bp
  • A to G, chromosome 5 at 75,195,036 bp
  • G to A, chromosome 6 at 29,326,607 bp
  • T to C, chromosome 6 at 81,923,882 bp
  • T to A, chromosome 6 at 132,737,719 bp
  • A to G, chromosome 6 at 136,933,580 bp
  • T to A, chromosome 7 at 15,758,007 bp
  • T to G, chromosome 7 at 17,905,207 bp
  • C to A, chromosome 7 at 19,057,669 bp
  • T to C, chromosome 7 at 43,694,110 bp
  • T to A, chromosome 7 at 46,072,487 bp
  • C to T, chromosome 7 at 104,068,125 bp
  • T to A, chromosome 7 at 106,818,361 bp
  • C to G, chromosome 8 at 109,623,649 bp
  • T to A, chromosome 8 at 119,590,732 bp
  • C to T, chromosome 9 at 8,900,778 bp
  • T to C, chromosome 9 at 96,024,191 bp
  • A to G, chromosome 10 at 21,996,358 bp
  • T to C, chromosome 10 at 25,994,104 bp
  • G to A, chromosome 10 at 116,113,153 bp
  • A to G, chromosome 10 at 121,417,204 bp
  • T to C, chromosome 11 at 55,498,626 bp
  • T to C, chromosome 11 at 59,163,439 bp
  • T to C, chromosome 11 at 98,203,579 bp
  • A to G, chromosome 12 at 4,267,687 bp
  • A to C, chromosome 12 at 98,242,645 bp
  • A to T, chromosome 12 at 98,489,945 bp
  • A to G, chromosome 13 at 49,430,865 bp
  • A to C, chromosome 13 at 100,161,782 bp
  • A to T, chromosome 14 at 55,635,526 bp
  • T to A, chromosome 14 at 123,291,047 bp
  • G to T, chromosome 15 at 36,099,795 bp
  • C to T, chromosome 15 at 103,497,427 bp
  • A to G, chromosome 16 at 4,039,149 bp
  • A to G, chromosome 17 at 24,313,177 bp
  • A to G, chromosome 17 at 34,736,127 bp
  • T to A, chromosome 17 at 75,282,429 bp
  • G to T, chromosome 18 at 37,449,224 bp
  • A to C, chromosome 18 at 78,350,090 bp
  • C to A, chromosome 19 at 12,120,536 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0467 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038667-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.