Strain Name:
C57BL/6J-MtgxR0498Btlr/Mmmh
Stock Number:
038694-MU
Citation ID:
RRID:MMRRC_038694-MU
Other Names:
R0498 (G1), C57BL/6J-MtgxR0498Btlr
Major Collection:

Gene Information

Vps33a
Name: VPS33A CORVET/HOPS core subunit
Synonyms: bf, 3830421M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 77573
Homologene: 11294
Tnrc6b
Name: trinucleotide repeat containing 6b
Synonyms: A730065C02Rik, 2700090M07Rik, D230019K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 213988
VEGA: 15
Homologene: 66194
Cacna1g
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms: a1G, Cav3.1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12291
HGNC: HGNC:1394
Homologene: 22544
Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Synonyms: 1810033J14Rik, 9530077A04Rik, D230038D11Rik, Mll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 69188
Homologene: 18822
Mtss1
Name: MTSS I-BAR domain containing 1
Synonyms: MIM, 2310003N14Rik, D130001D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 211401
VEGA: 15
Homologene: 8841
Pcm1
Name: pericentriolar material 1
Synonyms: 2600002H09Rik, C030044G17Rik, 9430077F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Arhgap21
Name: Rho GTPase activating protein 21
Synonyms: ARHGAP10, 5530401C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71435
Homologene: 10822
Map4k4
Name: mitogen-activated protein kinase kinase kinase kinase 4
Synonyms: Nik, 9430080K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 26921
HGNC: HGNC:6866
Homologene: 7442
Lta4h
Name: leukotriene A4 hydrolase
Synonyms: LTA4 hydrodase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16993
VEGA: 10
HGNC: HGNC:6710
Homologene: 6820
Armc8
Name: armadillo repeat containing 8
Synonyms: HSPC056, Gid5, 1200015K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74125
Homologene: 9121
Mms19
Name: MMS19 cytosolic iron-sulfur assembly component
Synonyms: Mms19l, 2610042O15Rik, C86341, Mms19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 72199
Homologene: 41480
Tmem87a
Name: transmembrane protein 87A
Synonyms: A930025J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 211499
Homologene: 9165
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: 4930400K19Rik, 2310003F20Rik, Garnl1, Tulip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 56784
VEGA: 12
Homologene: 84805
Dpp8
Name: dipeptidylpeptidase 8
Synonyms: 4932434F09Rik, 2310004I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74388
VEGA: 9
Homologene: 57098
Lepr
Name: leptin receptor
Synonyms: Leprb, LEPROT, Modb1, OB-RGRP, leptin receptor gene-related protein, obl, obese-like, Obr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16847
HGNC: HGNC:6554
Homologene: 1731
Kank4
Name: KN motif and ankyrin repeat domains 4
Synonyms: Ankrd38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242553
Homologene: 18244
Izumo4
Name: IZUMO family member 4
Synonyms: 9030607L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71564
VEGA: 10
Homologene: 50465
Mme
Name: membrane metallo endopeptidase
Synonyms: neprilysin, NEP, neutral endopeptidase, CD10, 6030454K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 17380
HGNC: HGNC:7154
Homologene: 5275
Map3k7
Name: mitogen-activated protein kinase kinase kinase 7
Synonyms: transforming growth factor-beta-activated kinase 1, Tak1, transforming growth factor beta-activated kinase 1, TGF-beta activated kinase 1, TAK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 26409
HGNC: HGNC:6859
Homologene: 118818
Anapc10
Name: anaphase promoting complex subunit 10
Synonyms: A830003M23Rik, Apc10, 1500026N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 68999
Homologene: 32238
Pprc1
Name: peroxisome proliferative activated receptor, gamma, coactivator-related 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226169
Homologene: 9006
Baz2b
Name: bromodomain adjacent to zinc finger domain, 2B
Synonyms: 5830435C13Rik, D2Ertd794e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 407823
HGNC: HGNC:963
Homologene: 8394
Brip1
Name: BRCA1 interacting protein C-terminal helicase 1
Synonyms: 3110009N10Rik, 8030460J03Rik, BACH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237911
Homologene: 32766
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: 2210407G14Rik, Hapip, E530005C20Rik, LOC224126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
4933406M09Rik
Name: RIKEN cDNA 4933406M09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240755
Homologene: 128441
Cubn
Name: cubilin (intrinsic factor-cobalamin receptor)
Synonyms: D2Wsu88e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Wdr63
Name: WD repeat domain 63
Synonyms: IC140, 4931433A13Rik, Ida7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242253
Homologene: 44922
Rnpep
Name: arginyl aminopeptidase (aminopeptidase B)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 215615
Homologene: 10628
Klra1
Name: killer cell lectin-like receptor, subfamily A, member 1
Synonyms: Ly49A, Ly49o129
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16627
Homologene: 110821
Tecta
Name: tectorin alpha
Synonyms: Tctna, [a]-tectorin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21683
Homologene: 3955
Myo3a
Name: myosin IIIA
Synonyms: 9030416P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 667663
HGNC: HGNC:7601
Homologene: 49486
Pdzph1
Name: PDZ and pleckstrin homology domains 1
Synonyms: 2610034M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 69239
Homologene: 130756
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 329628
Homologene: 14377
Fhod1
Name: formin homology 2 domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234686
Homologene: 136406
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Plekhs1
Name: pleckstrin homology domain containing, family S member 1
Synonyms: 9930023K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226245
VEGA: 19
Homologene: 11770
Serpina12
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
Synonyms: vaspin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68054
Homologene: 23588
Rpgrip1
Name: retinitis pigmentosa GTPase regulator interacting protein 1
Synonyms: 4930505G06Rik, nmf247, A930002K18Rik, 4930401L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 77945
Homologene: 10679
Tie1
Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Synonyms: TIE, tie-1, D430008P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 21846
Homologene: 3957
Fam38b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
Dsg1b
Name: desmoglein 1 beta
Synonyms: Dsg5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225256
HGNC: HGNC:3048
Homologene: 1463
Tmem30a
Name: transmembrane protein 30A
Synonyms: D9Wsu20e, Cdc50a, 2010200I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 69981
Homologene: 110703
Serpinb9f
Name: serine (or cysteine) peptidase inhibitor, clade B, member 9f
Synonyms: ovalbumin, NK21, Spi13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20709
HGNC: HGNC:8955
Homologene: 69093
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: B830017A01Rik, 3110047P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 319807
Homologene: 14974
Kdr
Name: kinase insert domain protein receptor
Synonyms: VEGF receptor-2, vascular endothelial growth factor receptor- 2, Flk-1, orv, Flk1, VEGFR-2, VEGFR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16542
HGNC: HGNC:6307
Homologene: 55639
Kbtbd11
Name: kelch repeat and BTB (POZ) domain containing 11
Synonyms: 4930465M17Rik, 2900016B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74901
Homologene: 28701
Ap1m2
Name: adaptor protein complex AP-1, mu 2 subunit
Synonyms: D9Ertd818e, [m]1B, mu1B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 11768
VEGA: 9
HGNC: HGNC:558
Homologene: 55906
Aldh18a1
Name: aldehyde dehydrogenase 18 family, member A1
Synonyms: 2810433K04Rik, Pycs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 56454
HGNC: HGNC:9722
Homologene: 2142
Serpinb3a
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A
Synonyms: Sqn5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20248
Homologene: 76659
Hoxc9
Name: homeobox C9
Synonyms: Hox-3.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 15427
HGNC: HGNC:5130
Homologene: 130558
CT030661.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
Ccdc66
Name: coiled-coil domain containing 66
Synonyms: E230015L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 320234
VEGA: 14
Homologene: 35309
Spata33
Name: spermatogenesis associated 33
Synonyms: 4732415M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320869
Homologene: 51900
Erp27
Name: endoplasmic reticulum protein 27
Synonyms: 1810047B09Rik, 1810033M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 69187
Homologene: 12303
Fcnaos
Name: ficolin A, opposite strand
Synonyms: Gm13520
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 102639143
Bpifa5
Name: BPI fold containing family A, member 5
Synonyms: 2310074B19Rik, 2310021H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67135
Homologene: 12087
Trpc4
Name: transient receptor potential cation channel, subfamily C, member 4
Synonyms: Trrp4, STRPC4, CCE1, Trp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 22066
Homologene: 22955
Asic5
Name: acid-sensing (proton-gated) ion channel family member 5
Synonyms: brain-liver-intestine amiloride-sensitive sodium channel, Accn5, BLINaC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 58170
Homologene: 41171
Saxo1
Name: stabilizer of axonemal microtubules 1
Synonyms: Fam154a, 4930500O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 75811
Homologene: 27548
Stard13
Name: StAR-related lipid transfer (START) domain containing 13
Synonyms: DLC2, GT650
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 243362
Homologene: 64844
4930433I11Rik
Name: RIKEN cDNA 4930433I11 gene
Synonyms: LOC243944
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243944
Homologene: 77912
Cbr4
Name: carbonyl reductase 4
Synonyms: A730083J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234309
Homologene: 57181
Tmem161a
Name: transmembrane protein 161A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234371
Homologene: 9853
Olfr874
Name: olfactory receptor 874
Synonyms: MOR161-2, GA_x6K02T2PVTD-31428850-31429782
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258882
Homologene: 17377
Tcrg-C3
Name: T cell receptor gamma, constant 3
Synonyms: Gm17356
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 107575
Vmn1r198
Name: vomeronasal 1 receptor 198
Synonyms: V1ri3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 171254
Homologene: 110880
6720489N17Rik
Name: RIKEN cDNA 6720489N17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 211378
Olfr727
Name: olfactory receptor 727
Synonyms: GA_x6K02T2PMLR-5817082-5818056, MOR246-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258316
Homologene: 84571
Adgrf2
Name: adhesion G protein-coupled receptor F2
Synonyms: Gpr111, PGR20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 435529
Homologene: 45213
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 39,990,178 bp
  • A to G, chromosome 1 at 107,047,150 bp
  • A to G, chromosome 1 at 134,390,872 bp
  • G to T, chromosome 1 at 135,265,352 bp
  • G to A, chromosome 2 at 13,444,267 bp
  • A to G, chromosome 2 at 20,863,117 bp
  • G to T, chromosome 2 at 22,577,429 bp
  • T to G, chromosome 2 at 25,627,645 bp
  • T to A, chromosome 2 at 41,458,405 bp
  • A to C, chromosome 2 at 59,901,996 bp
  • T to C, chromosome 2 at 76,709,581 bp
  • A to T, chromosome 2 at 120,394,465 bp
  • T to C, chromosome 2 at 154,167,249 bp
  • A to T, chromosome 3 at 38,980,637 bp
  • T to C, chromosome 3 at 54,291,211 bp
  • A to G, chromosome 3 at 63,346,066 bp
  • A to T, chromosome 3 at 82,006,471 bp
  • G to T, chromosome 3 at 146,081,364 bp
  • T to C, chromosome 4 at 31,974,814 bp
  • A to T, chromosome 4 at 86,478,896 bp
  • A to T, chromosome 4 at 98,779,636 bp
  • A to T, chromosome 4 at 101,745,692 bp
  • A to T, chromosome 4 at 118,479,161 bp
  • T to A, chromosome 5 at 23,478,972 bp
  • G to T, chromosome 5 at 63,806,343 bp
  • C to T, chromosome 5 at 75,959,138 bp
  • A to G, chromosome 5 at 123,570,961 bp
  • T to A, chromosome 5 at 151,052,477 bp
  • A to T, chromosome 6 at 130,372,819 bp
  • T to C, chromosome 6 at 136,919,864 bp
  • A to T, chromosome 7 at 40,993,294 bp
  • A to G, chromosome 8 at 15,027,605 bp
  • G to A, chromosome 8 at 41,293,769 bp
  • A to G, chromosome 8 at 61,495,073 bp
  • A to G, chromosome 8 at 70,180,973 bp
  • A to G, chromosome 8 at 79,774,981 bp
  • G to A, chromosome 8 at 105,329,856 bp
  • A to G, chromosome 8 at 123,221,923 bp
  • T to C, chromosome 9 at 21,295,833 bp
  • G to A, chromosome 9 at 37,746,254 bp
  • A to G, chromosome 9 at 42,377,614 bp
  • C to T, chromosome 9 at 65,045,795 bp
  • G to T, chromosome 9 at 79,774,094 bp
  • A to G, chromosome 9 at 99,497,292 bp
  • T to C, chromosome 10 at 80,704,196 bp
  • T to C, chromosome 10 at 93,471,971 bp
  • T to A, chromosome 11 at 86,197,919 bp
  • T to C, chromosome 11 at 94,459,859 bp
  • T to C, chromosome 12 at 55,689,791 bp
  • T to C, chromosome 12 at 104,035,789 bp
  • T to A, chromosome 13 at 19,261,092 bp
  • A to C, chromosome 13 at 22,354,974 bp
  • T to G, chromosome 13 at 33,326,007 bp
  • T to C, chromosome 13 at 62,607,387 bp
  • C to T, chromosome 14 at 27,500,240 bp
  • A to C, chromosome 14 at 50,127,293 bp
  • T to A, chromosome 14 at 52,131,314 bp
  • A to G, chromosome 15 at 58,945,437 bp
  • A to T, chromosome 15 at 80,858,719 bp
  • T to C, chromosome 15 at 102,983,927 bp
  • C to T, chromosome 16 at 34,054,891 bp
  • A to T, chromosome 17 at 22,200,901 bp
  • A to G, chromosome 17 at 42,714,315 bp
  • A to G, chromosome 17 at 58,973,830 bp
  • T to C, chromosome 18 at 20,409,333 bp
  • T to C, chromosome 18 at 63,102,174 bp
  • A to G, chromosome 19 at 40,574,272 bp
  • C to T, chromosome 19 at 41,949,773 bp
  • C to T, chromosome 19 at 46,071,568 bp
  • T to A, chromosome 19 at 56,481,104 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0498 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038694-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.