Strain Name:
C57BL/6J-MtgxR0503Btlr/Mmmh
Stock Number:
038698-MU
Citation ID:
RRID:MMRRC_038698-MU
Other Names:
R0503 (G1), C57BL/6J-MtgxR0503Btlr
Major Collection:

Gene Information

Dspp
Name: dentin sialophosphoprotein
Synonyms: Dmp3, Dpp, Dsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 666279
HGNC: HGNC:3054
Mmp10
Name: matrix metallopeptidase 10
Synonyms: stromelysin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17384
VEGA: 9
HGNC: HGNC:7156
Homologene: 20546
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, Acf7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11426
Homologene: 136191
Ptdss2
Name: phosphatidylserine synthase 2
Synonyms: PSS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 27388
Homologene: 8462
Comp
Name: cartilage oligomeric matrix protein
Synonyms: TSP5, thrombospondin-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12845
HGNC: HGNC:2227
Homologene: 74
Nbea
Name: neurobeachin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 26422
HGNC: HGNC:7648
Homologene: 69190
Mrps27
Name: mitochondrial ribosomal protein S27
Synonyms: 2610028H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218506
VEGA: 13
Homologene: 41006
Katnb1
Name: katanin p80 (WD40-containing) subunit B 1
Synonyms: 2410003J24Rik, KAT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74187
HGNC: HGNC:6217
Homologene: 4302
Ptprg
Name: protein tyrosine phosphatase, receptor type, G
Synonyms: RPTPgamma, 5430405N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19270
HGNC: HGNC:9671
Homologene: 2129
Gab1
Name: growth factor receptor bound protein 2-associated protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14388
HGNC: HGNC:4066
Homologene: 1542
Nefl
Name: neurofilament, light polypeptide
Synonyms: NF68, CMT2E, NF-L, Nfl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 18039
HGNC: HGNC:7739
Homologene: 4487
Crot
Name: carnitine O-octanoyltransferase
Synonyms: 1200003H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74114
HGNC: HGNC:2366
Homologene: 10899
Mphosph10
Name: M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
Synonyms: 5730405D16Rik, 2810453H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67973
HGNC: HGNC:7213
Homologene: 134741
Zkscan1
Name: zinc finger with KRAB and SCAN domains 1
Synonyms: 5930429A01Rik, 9230118B16Rik, KOX18, 9130423L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74570
Homologene: 34523
Polr3c
Name: polymerase (RNA) III (DNA directed) polypeptide C
Synonyms: 4933407E01Rik, RPC3, RPC62
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74414
Homologene: 38185
Pikfyve
Name: phosphoinositide kinase, FYVE type zinc finger containing
Synonyms: Pip5k3, 5230400C17Rik, PipkIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18711
Homologene: 32115
Irx4
Name: Iroquois homeobox 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 50916
HGNC: HGNC:6129
Homologene: 9485
Nktr
Name: natural killer tumor recognition sequence
Synonyms: D9Wsu172e, 5330401F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 18087
HGNC: HGNC:7833
Homologene: 122148
Kirrel
Name: kirre like nephrin family adhesion molecule 1
Synonyms: Neph1, Kirrel1, 6720469N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 170643
Homologene: 10089
Dapk1
Name: death associated protein kinase 1
Synonyms: 2810425C21Rik, 2310039H24Rik, DAP-Kinase, D13Ucla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 69635
VEGA: 13
HGNC: HGNC:2674
Homologene: 3626
Zfp940
Name: zinc finger protein 940
Synonyms: BC027344
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233057
Homologene: 138421
Pcdh15
Name: protocadherin 15
Synonyms: roda, nmf19, Ush1f, Gm9815
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11994
Homologene: 23401
Tspan11
Name: tetraspanin 11
Synonyms: 1110014F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 68498
Homologene: 23595
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
Homologene: 23741
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Zfyve9
Name: zinc finger, FYVE domain containing 9
Synonyms: Madhip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230597
HGNC: HGNC:6775
Homologene: 3527
Atp2c2
Name: ATPase, Ca++ transporting, type 2C, member 2
Synonyms: 1810010G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 69047
Homologene: 73463
Nlrp12
Name: NLR family, pyrin domain containing 12
Synonyms: Nalp12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 378425
Homologene: 16972
Serpina12
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
Synonyms: vaspin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68054
Homologene: 23588
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 245026
Homologene: 18260
Olfr1214
Name: olfactory receptor 1214
Synonyms: MOR233-8, GA_x6K02T2Q125-50468705-50467770
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258899
Homologene: 73984
Unc79
Name: unc-79 homolog
Synonyms: Mlca3, 9030205A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217843
Homologene: 41397
Vmn2r85
Name: vomeronasal 2, receptor 85
Synonyms: EG623734
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 623734
Homologene: 129606
Cd200r2
Name: Cd200 receptor 2
Synonyms: CD200 cell surface glycoprotein receptor isoform 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 271375
Homologene: 45557
Nsun7
Name: NOL1/NOP2/Sun domain family, member 7
Synonyms: 4921525L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70918
Homologene: 11653
Tyro3
Name: TYRO3 protein tyrosine kinase 3
Synonyms: Dtk, Tif, Etk-2, Brt, Sky, Rse, Sky
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22174
Homologene: 4585
Olfr729
Name: olfactory receptor 729
Synonyms: MOR246-6, GA_x6K02T2PMLR-5839874-5838903
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258275
Homologene: 17167
Gria1
Name: glutamate receptor, ionotropic, AMPA1 (alpha 1)
Synonyms: 2900051M01Rik, GluR-A, Glur-1, Glr1, GluA1, GluRA, Glr-1, HIPA1, GluR1, Glur1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14799
HGNC: HGNC:4571
Homologene: 20226
Mybpc2
Name: myosin binding protein C, fast-type
Synonyms: Fast-type C-protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233199
HGNC: HGNC:7550
Homologene: 3331
Rfx4
Name: regulatory factor X, 4 (influences HLA class II expression)
Synonyms: 4933412G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71137
HGNC: HGNC:9985
Homologene: 31119
Ptpru
Name: protein tyrosine phosphatase, receptor type, U
Synonyms: Ptprl, RPTPlambda
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Olfr961
Name: olfactory receptor 961
Synonyms: GA_x6K02T2PVTD-33343617-33344561, MOR224-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258497
VEGA: 9
Homologene: 74020
Ttll10
Name: tubulin tyrosine ligase-like family, member 10
Synonyms: 4930595O22Rik, 4833412E22Rik, Ttll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 330010
Homologene: 51912
Vmn1r196
Name: vomeronasal 1 receptor 196
Synonyms: V1rh19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 100312484
Homologene: 110880
Nck2
Name: non-catalytic region of tyrosine kinase adaptor protein 2
Synonyms: 4833426I10Rik, Grb4, NCKbeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17974
HGNC: HGNC:7665
Homologene: 20794
Ccdc65
Name: coiled-coil domain containing 65
Synonyms: 4933417K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105833
VEGA: 15
Homologene: 13226
Tmem39b
Name: transmembrane protein 39b
Synonyms: 6330509E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230770
Homologene: 23069
Olfr586
Name: olfactory receptor 586
Synonyms: MOR8-2, MOR8-7, GA_x6K02T2PBJ9-5836380-5835439
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259115
Homologene: 131143
9930111J21Rik1
Name: RIKEN cDNA 9930111J21 gene 1
Synonyms: 9930111J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 667214
Homologene: 83188
Erich2
Name: glutamate rich 2
Synonyms: 4933404M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66748
Homologene: 75226
Clca4c-ps
Name: chloride channel accessory 4C, pseudogene
Synonyms: Gm6289, Gm18718, Clca4c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 622139
Ggcx
Name: gamma-glutamyl carboxylase
Synonyms: vitamin K-dependent carboxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 56316
HGNC: HGNC:4247
Homologene: 639
Olfr523
Name: olfactory receptor 523
Synonyms: GA_x6K02T2PBJ9-42327937-42328872, MOR104-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258511
Homologene: 27191
AI646023
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Olfr769
Name: olfactory receptor 769
Synonyms: GA_x6K02T2PULF-10797876-10796938, MOR114-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 257667
Homologene: 121502
G6bos
Name: G6b opposite strand
Synonyms: G6b, NG31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 114763
VEGA: 17
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 43,533,568 bp
  • A to T, chromosome 1 at 65,219,899 bp
  • C to T, chromosome 1 at 150,859,252 bp
  • A to T, chromosome 2 at 70,509,699 bp
  • C to A, chromosome 2 at 70,540,775 bp
  • C to T, chromosome 2 at 88,987,978 bp
  • T to C, chromosome 2 at 119,803,230 bp
  • C to T, chromosome 3 at 55,642,836 bp
  • A to G, chromosome 3 at 87,097,802 bp
  • A to T, chromosome 3 at 96,713,636 bp
  • A to T, chromosome 3 at 144,879,822 bp
  • A to T, chromosome 4 at 108,719,764 bp
  • A to G, chromosome 4 at 123,469,815 bp
  • A to C, chromosome 4 at 129,686,986 bp
  • T to C, chromosome 4 at 131,793,643 bp
  • T to C, chromosome 4 at 156,047,548 bp
  • A to G, chromosome 5 at 8,976,075 bp
  • T to A, chromosome 5 at 66,283,581 bp
  • A to T, chromosome 5 at 104,177,256 bp
  • T to A, chromosome 5 at 138,093,326 bp
  • GTCTAT to GTCTATCTAT, chromosome 6 at 72,429,157 bp
  • T to C, chromosome 6 at 127,939,112 bp
  • C to T, chromosome 7 at 3,249,377 bp
  • A to G, chromosome 7 at 29,846,020 bp
  • A to G, chromosome 7 at 44,512,570 bp
  • A to T, chromosome 7 at 64,389,893 bp
  • A to T, chromosome 7 at 103,122,436 bp
  • T to C, chromosome 7 at 140,176,441 bp
  • T to A, chromosome 7 at 141,151,797 bp
  • G to T, chromosome 7 at 141,638,772 bp
  • A to T, chromosome 8 at 70,375,734 bp
  • C to T, chromosome 8 at 80,800,142 bp
  • A to G, chromosome 8 at 95,095,174 bp
  • A to G, chromosome 8 at 119,734,577 bp
  • A to T, chromosome 9 at 7,507,339 bp
  • A to G, chromosome 9 at 39,647,476 bp
  • A to T, chromosome 9 at 105,767,351 bp
  • T to A, chromosome 9 at 121,750,740 bp
  • A to G, chromosome 10 at 74,210,385 bp
  • T to C, chromosome 10 at 75,553,654 bp
  • T to A, chromosome 10 at 84,894,332 bp
  • T to C, chromosome 10 at 129,111,802 bp
  • T to C, chromosome 10 at 130,422,740 bp
  • T to C, chromosome 11 at 48,947,495 bp
  • T to G, chromosome 11 at 57,189,716 bp
  • A to G, chromosome 12 at 103,078,868 bp
  • C to A, chromosome 12 at 104,031,159 bp
  • G to A, chromosome 13 at 22,293,387 bp
  • T to A, chromosome 13 at 60,730,848 bp
  • T to A, chromosome 13 at 73,266,584 bp
  • G to T, chromosome 13 at 99,409,795 bp
  • A to G, chromosome 14 at 12,237,138 bp
  • T to A, chromosome 14 at 50,148,478 bp
  • T to A, chromosome 14 at 68,083,983 bp
  • G to T, chromosome 15 at 98,709,160 bp
  • T to A, chromosome 16 at 44,877,962 bp
  • A to G, chromosome 17 at 35,064,448 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0503 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038698-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.