Strain Name:
C57BL/6J-MtgxR0529Btlr/Mmmh
Stock Number:
038721-MU
Citation ID:
RRID:MMRRC_038721-MU
Other Names:
R0529 (G1), C57BL/6J-MtgxR0529Btlr
Major Collection:

Gene Information

Drd2
Name: dopamine receptor D2
Synonyms: D2 receptor, Drd-2, D2R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13489
VEGA: 9
HGNC: HGNC:3023
Homologene: 22561
Cnmd
Name: chondromodulin
Synonyms: Chondromodulin 1, Chmd, ChM-I, Bricd3, Lect1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16840
Homologene: 5095
Gtf2i
Name: general transcription factor II I
Synonyms: TFII-I, BAP-135, 6030441I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14886
HGNC: HGNC:4659
Homologene: 7748
Dnmt1
Name: DNA methyltransferase (cytosine-5) 1
Synonyms: MommeD2, Cxxc9, Dnmt1o, MTase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13433
VEGA: 9
HGNC: HGNC:2976
Homologene: 124071
Plcd3
Name: phospholipase C, delta 3
Synonyms: 2610205J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72469
HGNC: HGNC:9061
Homologene: 14858
Gpatch4
Name: G patch domain containing 4
Synonyms: Gpatc4, 2610029K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66614
Homologene: 9203
Aasdh
Name: aminoadipate-semialdehyde dehydrogenase
Synonyms: A230062G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231326
Homologene: 71711
Mtmr14
Name: myotubularin related protein 14
Synonyms: 1110061O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 97287
Homologene: 11203
Gpr55
Name: G protein-coupled receptor 55
Synonyms: LOC227326, CTFL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227326
HGNC: HGNC:4511
Homologene: 36184
Dyrk3
Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226419
HGNC: HGNC:3094
Homologene: 55762
Fbxo38
Name: F-box protein 38
Synonyms: SP329, 6030410I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 107035
VEGA: 18
Homologene: 34526
Nsmce4a
Name: NSE4 homolog A, SMC5-SMC6 complex component
Synonyms: 2410003A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67872
Homologene: 9745
Psmc5
Name: protease (prosome, macropain) 26S subunit, ATPase 5
Synonyms: mSUG1, Rpt6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19184
HGNC: HGNC:9552
Homologene: 2098
Cebpa
Name: CCAAT/enhancer binding protein (C/EBP), alpha
Synonyms: C/EBP alpha, C/ebpalpha, Cebp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12606
HGNC: HGNC:1833
Homologene: 3211
Dmp1
Name: dentin matrix protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13406
HGNC: HGNC:2932
Homologene: 68396
Drd3
Name: dopamine receptor D3
Synonyms: D3 receptor, D3R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13490
VEGA: 16
HGNC: HGNC:3024
Homologene: 623
Gda
Name: guanine deaminase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14544
HGNC: HGNC:4212
Homologene: 3171
Zfy1
Name: zinc finger protein 1, Y-linked
Synonyms: Zfy-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 22767
Homologene: 56456
Knstrn
Name: kinetochore-localized astrin/SPAG5 binding
Synonyms: 1700025D04Rik, D2Ertd750e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51944
Homologene: 12198
Psmd11
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Synonyms: 1810019E17Rik, S9, P44.5, 1700089D09Rik, C78232, 2810055C24Rik, 2610024G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69077
HGNC: HGNC:9556
Homologene: 2108
Fmnl2
Name: formin-like 2
Synonyms: 5430425K04Rik, man
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71409
Homologene: 70871
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: A2mr, b2b1554Clo, CD91
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: fibrocystin L, D86 mRNA, PKHDL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 192190
Homologene: 16332
Trappc11
Name: trafficking protein particle complex 11
Synonyms: D030016E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 320714
Homologene: 11076
Slc35e1
Name: solute carrier family 35, member E1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270066
Homologene: 49075
Cul9
Name: cullin 9
Synonyms: 1810035I07Rik, Parc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 78309
Homologene: 56696
1700010I14Rik
Name: RIKEN cDNA 1700010I14 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66931
Homologene: 49841
Afp
Name: alpha fetoprotein
Synonyms: alpha-foetoprotein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11576
HGNC: HGNC:317
Homologene: 36278
Tmem63a
Name: transmembrane protein 63a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208795
Homologene: 101673
Frmd4a
Name: FERM domain containing 4A
Synonyms: 2700017I06Rik, C230040M21Rik, Gm13190
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 209630
Homologene: 9971
Fbxw10
Name: F-box and WD-40 domain protein 10
Synonyms: Fbw10, SM25H2, SM2SH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 213980
Homologene: 32757
Vmn2r18
Name: vomeronasal 2, receptor 18
Synonyms: EG632671
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 632671
Phlpp2
Name: PH domain and leucine rich repeat protein phosphatase 2
Synonyms: C130044A18Rik, Phlppl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244650
Homologene: 71015
Cyld
Name: CYLD lysine 63 deubiquitinase
Synonyms: CYLD1, 2900009M21Rik, 2010013M14Rik, C130039D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74256
HGNC: HGNC:2584
Homologene: 9069
Traf3ip3
Name: TRAF3 interacting protein 3
Synonyms: 6030423D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 215243
Homologene: 11885
Cntln
Name: centlein, centrosomal protein
Synonyms: D530005L17Rik, B430108F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 338349
Homologene: 9805
Tent5c
Name: terminal nucleotidyltransferase 5C
Synonyms: Fam46c, 4930431B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74645
Homologene: 56783
Axl
Name: AXL receptor tyrosine kinase
Synonyms: Tyro7, Ark, Ufo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26362
HGNC: HGNC:905
Homologene: 7583
Arhgef26
Name: Rho guanine nucleotide exchange factor (GEF) 26
Synonyms: 8430436L14Rik, 4631416L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 622434
Homologene: 9204
Lipo2
Name: lipase, member O2
Synonyms: Gm8981
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 101055671
Homologene: 103863
Rab39
Name: RAB39, member RAS oncogene family
Synonyms: C230094F14Rik, Rab39a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270160
Homologene: 56773
Tnk1
Name: tyrosine kinase, non-receptor, 1
Synonyms: Tnk1a, Tnk1b, Kos1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 83813
Homologene: 2966
Wipf3
Name: WAS/WASL interacting protein family, member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330319
Homologene: 113391
Yipf5
Name: Yip1 domain family, member 5
Synonyms: Yip1a, 2610311I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67180
VEGA: 18
Homologene: 56969
Ric8a
Name: RIC8 guanine nucleotide exchange factor A
Synonyms: RIC-8, Ric8, synembryn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101489
Homologene: 23331
Fmn1
Name: formin 1
Synonyms: formin-1, Fmn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14260
HGNC: HGNC:3768
Homologene: 121778
Rtp3
Name: receptor transporter protein 3
Synonyms: Tmem7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235636
Homologene: 135957
Vmn2r12
Name: vomeronasal 2, receptor 12
Synonyms: Gm6769
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 627569
Homologene: 129606
Serpina1e
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1E
Synonyms: PI5, Spi1-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20704
HGNC: HGNC:8941
Homologene: 20103
Olfr421-ps1
Name: olfactory receptor 421, pseudogene 1
Synonyms: MOR105-3, GA_x6K02T2P20D-21006310-21006124, GA_x6K02T2P20D-21002372-21001425, Olfr422-ps1, Olfr421
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258715
Vmn1r7
Name: vomeronasal 1 receptor 7
Synonyms: V1rc31, Gm5568
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 434016
Homologene: 83427
Vmn1r174
Name: vomeronasal 1 receptor 174
Synonyms: V1rd22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 404291
Homologene: 79577
Olfr917
Name: olfactory receptor 917
Synonyms: MOR168-2P, GA_x6K02T2PVTD-32368166-32367237
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258183
VEGA: 9
Zbtb7a
Name: zinc finger and BTB domain containing 7a
Synonyms: Lrf, Leukemia/lymphoma Related Factor, Zbtb7, Pokemon, 9130006G12Rik, 9030619K07Rik, FBI-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16969
Homologene: 7820
Ccdc71l
Name: coiled-coil domain containing 71 like
Synonyms: 2010109K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 72123
Homologene: 77589
Aldh5a1
Name: aldhehyde dehydrogenase family 5, subfamily A1
Synonyms: SSADH, OTTMUSG00000000613, 6330403E24Rik, D630032B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 214579
HGNC: HGNC:408
Homologene: 840
Card10
Name: caspase recruitment domain family, member 10
Synonyms: CARMA3, Bimp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105844
Homologene: 8728
Oacyl
Name: O-acyltransferase like
Synonyms: 5330437I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 319888
Homologene: 129774
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 85,941,503 bp
  • A to G, chromosome 1 at 131,130,121 bp
  • G to A, chromosome 1 at 174,152,130 bp
  • A to T, chromosome 1 at 180,961,094 bp
  • G to T, chromosome 1 at 193,194,811 bp
  • A to G, chromosome 2 at 4,606,023 bp
  • A to T, chromosome 2 at 53,042,365 bp
  • T to A, chromosome 2 at 113,707,853 bp
  • T to A, chromosome 2 at 118,830,980 bp
  • T to C, chromosome 3 at 62,339,725 bp
  • T to A, chromosome 3 at 88,051,276 bp
  • A to G, chromosome 3 at 100,472,370 bp
  • T to A, chromosome 4 at 85,067,825 bp
  • A to C, chromosome 5 at 76,876,267 bp
  • A to G, chromosome 5 at 90,504,395 bp
  • A to G, chromosome 5 at 104,212,226 bp
  • A to G, chromosome 5 at 109,092,848 bp
  • A to T, chromosome 5 at 134,261,869 bp
  • T to A, chromosome 5 at 151,562,523 bp
  • C to A, chromosome 6 at 54,485,363 bp
  • T to A, chromosome 6 at 57,024,465 bp
  • T to C, chromosome 6 at 113,266,252 bp
  • G to A, chromosome 7 at 23,754,197 bp
  • A to G, chromosome 7 at 25,787,287 bp
  • A to T, chromosome 7 at 35,120,199 bp
  • A to T, chromosome 7 at 130,533,806 bp
  • A to G, chromosome 7 at 140,860,893 bp
  • A to G, chromosome 8 at 47,526,979 bp
  • T to C, chromosome 8 at 72,492,571 bp
  • A to G, chromosome 8 at 88,729,759 bp
  • T to C, chromosome 8 at 109,876,971 bp
  • T to C, chromosome 9 at 20,911,550 bp
  • A to T, chromosome 9 at 38,665,512 bp
  • A to C, chromosome 9 at 49,407,074 bp
  • T to C, chromosome 9 at 53,686,716 bp
  • T to C, chromosome 9 at 110,987,084 bp
  • G to A, chromosome 10 at 81,143,986 bp
  • T to C, chromosome 10 at 127,541,594 bp
  • A to C, chromosome 11 at 62,859,845 bp
  • T to C, chromosome 11 at 69,855,164 bp
  • T to C, chromosome 11 at 80,470,689 bp
  • T to G, chromosome 11 at 103,080,187 bp
  • G to A, chromosome 11 at 106,261,164 bp
  • G to A, chromosome 12 at 32,379,252 bp
  • A to C, chromosome 12 at 103,949,104 bp
  • G to T, chromosome 13 at 24,913,873 bp
  • T to C, chromosome 14 at 79,642,041 bp
  • T to A, chromosome 15 at 44,526,754 bp
  • A to G, chromosome 15 at 78,780,475 bp
  • G to A, chromosome 16 at 43,822,714 bp
  • G to A, chromosome 17 at 8,992,396 bp
  • A to G, chromosome 17 at 46,520,468 bp
  • A to T, chromosome 18 at 40,212,162 bp
  • T to C, chromosome 18 at 62,505,986 bp
  • T to A, chromosome 18 at 65,742,219 bp
  • T to A, chromosome 19 at 21,425,537 bp
  • T to A, chromosome 19 at 33,746,935 bp
  • G to T, chromosome Y at 726,040 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0529 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038721-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.