Strain Name:
C57BL/6J-MtgxR0534Btlr/Mmmh
Stock Number:
038726-MU
Citation ID:
RRID:MMRRC_038726-MU
Other Names:
R0534 (G1), C57BL/6J-MtgxR0534Btlr
Major Collection:

Gene Information

Igf2bp1
Name: insulin-like growth factor 2 mRNA binding protein 1
Synonyms: D11Moh40e, D11Moh45, Zbp1, IMP-1, IMP1, Crdbp, CRD-BP, D030026A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 140486
Homologene: 4772
Gpr37
Name: G protein-coupled receptor 37
Synonyms: parkin-associated endothelin B-like receptor, Pael-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14763
HGNC: HGNC:4494
Homologene: 3875
Npy1r
Name: neuropeptide Y receptor Y1
Synonyms: Y1-R, Npyr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 18166
HGNC: HGNC:7956
Homologene: 700
Tlr9
Name: toll-like receptor 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 81897
Homologene: 68126
Dop1b
Name: DOP1 leucine zipper like protein B
Synonyms: Dopey2, 2610510B01Rik, 0610038M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 70028
VEGA: 16
HGNC: HGNC:1291
Homologene: 21068
Sipa1l1
Name: signal-induced proliferation-associated 1 like 1
Synonyms: Spar, 4931426N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217692
VEGA: 12
Homologene: 9189
Denn2b
Name: DENN domain containing 2B
Synonyms: St5, 2610305K15Rik, 2010004M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76954
Homologene: 3951
Cwc27
Name: CWC27 spliceosome-associated protein
Synonyms: 3110009E13Rik, Sdccag10, NY-CO-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 67285
Homologene: 21192
Wdr59
Name: WD repeat domain 59
Synonyms: 5430401O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 319481
Homologene: 38685
Tmem104
Name: transmembrane protein 104
Synonyms: C630005D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 320534
Homologene: 9802
Ep300
Name: E1A binding protein p300
Synonyms: p300, KAT3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 328572
HGNC: HGNC:3373
Homologene: 1094
Cap1
Name: CAP, adenylate cyclase-associated protein 1 (yeast)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12331
Homologene: 74572
Zfp622
Name: zinc finger protein 622
Synonyms: D15Ertd806e, 1110033B05Rik, ZPR9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 52521
VEGA: 15
Homologene: 74377
Gpbp1l1
Name: GC-rich promoter binding protein 1-like 1
Synonyms: 5330440M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 77110
Homologene: 84840
Gm3604
Name: predicted gene 3604
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 100041979
Homologene: 136271
Rmdn3
Name: regulator of microtubule dynamics 3
Synonyms: Fam82a2, 1200015F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67809
Homologene: 34926
E2f4
Name: E2F transcription factor 4
Synonyms: 2010111M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 104394
HGNC: HGNC:3118
Homologene: 1471
Cand2
Name: cullin-associated and neddylation-dissociated 2 (putative)
Synonyms: 2210404G23Rik, Tp120b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67088
Homologene: 41657
Cxxc1
Name: CXXC finger 1 (PHD domain)
Synonyms: Cfp1, 2410002I16Rik, 5830420C16Rik, PHF18, Cgbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 74322
VEGA: 18
Homologene: 32221
Osbpl10
Name: oxysterol binding protein-like 10
Synonyms: OPR-10, 4933433D06Rik, C820004B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74486
Homologene: 69240
Fads1
Name: fatty acid desaturase 1
Synonyms: 0710001O03Rik, A930006B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 76267
VEGA: 19
HGNC: HGNC:3574
Homologene: 22753
Flcn
Name: folliculin
Synonyms: B430214A04Rik, BHD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216805
Homologene: 14583
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 269700
Homologene: 28297
Gtf3c2
Name: general transcription factor IIIC, polypeptide 2, beta
Synonyms: TFIIIC110, TFIIIC-BETA, 1300004C11Rik, 2610510G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71752
HGNC: HGNC:4665
Homologene: 37490
Fign
Name: fidgetin
Synonyms: Fgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 60344
Homologene: 5813
Kcnv1
Name: potassium channel, subfamily V, member 1
Synonyms: 2700023A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 67498
VEGA: 15
Homologene: 22811
P2rx6
Name: purinergic receptor P2X, ligand-gated ion channel, 6
Synonyms: P2xm, P2rxl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 18440
HGNC: HGNC:8538
Homologene: 3975
Scnn1g
Name: sodium channel, nonvoltage-gated 1 gamma
Synonyms: ENaC gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20278
Homologene: 20280
Reln
Name: reelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Pkd1l3
Name: polycystic kidney disease 1 like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244646
Homologene: 14627
Hrc
Name: histidine rich calcium binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 15464
HGNC: HGNC:5178
Homologene: 137234
Psmc1
Name: protease (prosome, macropain) 26S subunit, ATPase 1
Synonyms: S4, rpt2, Rpt2/S4, P26s4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 19179
VEGA: 12
HGNC: HGNC:9547
Homologene: 2095
Dscam
Name: DS cell adhesion molecule
Synonyms: Down syndrome cell adhesion molecule, 4932410A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Il23r
Name: interleukin 23 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 209590
Homologene: 16930
Ccdc110
Name: coiled-coil domain containing 110
Synonyms: LOC212392
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 212392
Homologene: 17668
Lipe
Name: lipase, hormone sensitive
Synonyms: HSL, 4933403G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16890
HGNC: HGNC:6621
Homologene: 3912
Cps1
Name: carbamoyl-phosphate synthetase 1
Synonyms: CPSase I, D1Ucla3, CPS, 4732433M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227231
HGNC: HGNC:2323
Homologene: 68208
Igsf9b
Name: immunoglobulin superfamily, member 9B
Synonyms: LOC235086
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235086
Homologene: 19472
Mdga1
Name: MAM domain containing glycosylphosphatidylinositol anchor 1
Synonyms: Mamdc3, 1200011I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74762
Homologene: 17780
Olfr64
Name: olfactory receptor 64
Synonyms: GA_x6K02T2PBJ9-6648196-6649143, 5'[b]2, MOR1-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18366
Homologene: 56593
Lrrcc1
Name: leucine rich repeat and coiled-coil domain containing 1
Synonyms: 4932441F23Rik, 1200008A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71710
Homologene: 12559
Phyhip
Name: phytanoyl-CoA hydroxylase interacting protein
Synonyms: PAHX-AP1, C630010D02Rik, PAHX-AP#1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105653
Homologene: 8847
Myrf
Name: myelin regulatory factor
Synonyms: LOC225908, LOC386531, Gm98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225908
HGNC: HGNC:1181
Homologene: 32167
4933416C03Rik
Name: RIKEN cDNA 4933416C03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Hcfc2
Name: host cell factor C2
Synonyms: fkls, 1700129L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67933
Homologene: 8337
Shcbp1l
Name: Shc SH2-domain binding protein 1-like
Synonyms: 1700012A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71836
Homologene: 12800
Timp4
Name: tissue inhibitor of metalloproteinase 4
Synonyms: TIMP-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 110595
Homologene: 37748
Soga3
Name: SOGA family member 3
Synonyms: 6330407J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67412
VEGA: 10
Homologene: 28227
Mrpl54
Name: mitochondrial ribosomal protein L54
Synonyms: D10Sut1e, 0610008M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66047
Homologene: 11910
Nt5el
Name: 5' nucleotidase, ecto-like
Synonyms: 4933425L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66763
Homologene: 12028
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 67,143,900 bp
  • T to A, chromosome 1 at 153,428,568 bp
  • T to A, chromosome 2 at 63,980,791 bp
  • T to C, chromosome 2 at 119,146,370 bp
  • T to C, chromosome 3 at 14,557,273 bp
  • T to A, chromosome 4 at 116,591,268 bp
  • C to T, chromosome 4 at 122,862,719 bp
  • A to T, chromosome 5 at 21,947,408 bp
  • A to T, chromosome 5 at 31,158,132 bp
  • T to C, chromosome 5 at 121,348,476 bp
  • A to T, chromosome 6 at 25,669,824 bp
  • G to A, chromosome 6 at 67,426,588 bp
  • A to G, chromosome 6 at 115,249,841 bp
  • A to G, chromosome 6 at 115,787,236 bp
  • C to A, chromosome 7 at 25,388,186 bp
  • AGAGGAGGAGGAAGAGGAGGAGGA to AGAGGAGGAGGAGGAAGAGGAGGAGGA, chromosome 7 at 45,337,235 bp
  • C to T, chromosome 7 at 103,893,231 bp
  • A to T, chromosome 7 at 109,541,428 bp
  • A to G, chromosome 7 at 121,767,424 bp
  • T to C, chromosome 8 at 45,935,138 bp
  • C to A, chromosome 8 at 66,705,018 bp
  • C to A, chromosome 8 at 105,304,219 bp
  • C to G, chromosome 8 at 109,623,649 bp
  • GGGTGGTG to GGGTG, chromosome 8 at 111,480,540 bp
  • T to G, chromosome 9 at 27,333,062 bp
  • T to A, chromosome 9 at 106,224,887 bp
  • C to T, chromosome 9 at 115,167,178 bp
  • T to A, chromosome 10 at 29,180,956 bp
  • C to A, chromosome 10 at 81,266,853 bp
  • T to A, chromosome 10 at 82,738,408 bp
  • T to C, chromosome 10 at 116,112,802 bp
  • T to A, chromosome 11 at 59,794,199 bp
  • A to G, chromosome 11 at 95,966,796 bp
  • C to A, chromosome 11 at 115,200,828 bp
  • T to C, chromosome 12 at 82,425,280 bp
  • T to A, chromosome 12 at 100,120,130 bp
  • A to T, chromosome 13 at 62,774,594 bp
  • T to A, chromosome 13 at 104,631,616 bp
  • C to A, chromosome 13 at 105,082,254 bp
  • A to T, chromosome 14 at 70,461,759 bp
  • A to T, chromosome 15 at 25,984,568 bp
  • A to G, chromosome 15 at 45,109,249 bp
  • A to G, chromosome 15 at 81,600,896 bp
  • A to C, chromosome 16 at 17,567,904 bp
  • T to A, chromosome 16 at 93,762,505 bp
  • G to T, chromosome 16 at 96,652,172 bp
  • T to C, chromosome 17 at 29,832,900 bp
  • C to T, chromosome 18 at 74,218,891 bp
  • C to T, chromosome 19 at 10,183,065 bp
  • G to C, chromosome 19 at 10,218,162 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0534 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038726-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.