Strain Name:
C57BL/6J-MtgxR0582Btlr/Mmmh
Stock Number:
038772-MU
Citation ID:
RRID:MMRRC_038772-MU
Other Names:
R0582 (G1), C57BL/6J-MtgxR0582Btlr
Major Collection:

Gene Information

Pdyn
Name: prodynorphin
Synonyms: Dyn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18610
HGNC: HGNC:8820
Homologene: 10321
Ctnnal1
Name: catenin (cadherin associated protein), alpha-like 1
Synonyms: ACRP, Catnal1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 54366
HGNC: HGNC:2512
Homologene: 2815
Vps54
Name: VPS54 GARP complex subunit
Synonyms: wr, 5330404P15Rik, mSLP8, Vps54l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245944
Homologene: 5605
Dscaml1
Name: DS cell adhesion molecule like 1
Synonyms: 4921507G06Rik, 4930435C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 114873
VEGA: 9
Homologene: 79549
Snx3
Name: sorting nexin 3
Synonyms: SDP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 54198
Homologene: 36144
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: Bruce, D630005A10Rik, A430040A19Rik, apollon, A430032G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Prpf40a
Name: pre-mRNA processing factor 40A
Synonyms: 2810012K09Rik, Fnbp3, FBP11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56194
Homologene: 6377
Ints9
Name: integrator complex subunit 9
Synonyms: D14Ertd231e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 210925
VEGA: 14
Homologene: 10096
Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Synonyms: Nrf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18024
HGNC: HGNC:7782
Homologene: 2412
Lyn
Name: LYN proto-oncogene, Src family tyrosine kinase
Synonyms: Yamaguchi sarcoma viral (v-yes-1) oncogene homolog, Hck-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17096
HGNC: HGNC:6735
Homologene: 55649
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: P1-Loop, Hst6.7b, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Ccdc50
Name: coiled-coil domain containing 50
Synonyms: 5730448P06Rik, 2610529H08Rik, D16Bwg1543e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67501
Homologene: 69406
Zfyve26
Name: zinc finger, FYVE domain containing 26
Synonyms: A630028O16Rik, LOC380767, 9330197E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 211978
VEGA: 12
Homologene: 9102
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171395
Homologene: 51376
Slc7a8
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
Synonyms: LAT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50934
VEGA: 14
Homologene: 8166
Sycp2l
Name: synaptonemal complex protein 2-like
Synonyms: EG621792, Gm40956, LOC218175
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 637277
Homologene: 52882
Afm
Name: afamin
Synonyms: alpha albumin, Alf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 280662
HGNC: HGNC:316
Homologene: 881
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: mXin beta, myomaxin, 2310008C07Rik, Cmya3, A530024P18Rik, 2310003D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241431
Homologene: 19388
Gm4981
Name: predicted gene 4981
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 245263
Homologene: 134545
Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Synonyms: aromatic compound inducible, CP12, P450-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13077
VEGA: 9
HGNC: HGNC:2596
Homologene: 68082
Wdr53
Name: WD repeat domain 53
Synonyms: 1500002B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 68980
Homologene: 15591
Ccdc150
Name: coiled-coil domain containing 150
Synonyms: 4930511H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78016
Homologene: 15814
Igsf10
Name: immunoglobulin superfamily, member 10
Synonyms: 6530405F15Rik, CMF608, Adlican2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242050
Homologene: 18712
Abcb5
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 5
Synonyms: 9230106F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 77706
HGNC: HGNC:46
Homologene: 83488
Arfgef3
Name: ARFGEF family member 3
Synonyms: B930094H20Rik, BIG3, D10Bwg1379e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215821
VEGA: 10
Homologene: 41366
Cntln
Name: centlein, centrosomal protein
Synonyms: D530005L17Rik, B430108F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 338349
Homologene: 9805
Vmn2r27
Name: vomeronasal 2, receptor27
Synonyms: EG232367
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232367
Snap47
Name: synaptosomal-associated protein, 47
Synonyms: SNAP-47, 1110031B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67826
Homologene: 14206
Atp11a
Name: ATPase, class VI, type 11A
Synonyms: 9130422H11Rik, Ih, 4930558F19Rik, LOC100045280
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 50770
Homologene: 75050
Olfr628
Name: olfactory receptor 628
Synonyms: MOR22-4P, Olfr1526-ps1, GA_x6K02T2PBJ9-6457667-6458617, MOR22-1, MOR22-4P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259159
Homologene: 8420
Ttc28
Name: tetratricopeptide repeat domain 28
Synonyms: TPRBK, 2310015L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 209683
Homologene: 41023
9230019H11Rik
Name: RIKEN cDNA 9230019H11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215728
VEGA: 10
Ctnna2
Name: catenin (cadherin associated protein), alpha 2
Synonyms: alpha(N)-catenin, chp, Catna, alpha N-catenin, Catna2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12386
HGNC: HGNC:2510
Homologene: 68394
Ears2
Name: glutamyl-tRNA synthetase 2, mitochondrial
Synonyms: 3230401I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67417
Homologene: 6907
Sema6c
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
Synonyms: Semay, Sema Y
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20360
Homologene: 7931
Olfr92
Name: olfactory receptor 92
Synonyms: MOR256-29, GA_x6K02T2PSCP-1552066-1551128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258448
HGNC: HGNC:8253
Homologene: 115562
Tm4sf4
Name: transmembrane 4 superfamily member 4
Synonyms: il-TMP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229302
Homologene: 3393
Ipp
Name: IAP promoted placental gene
Synonyms: Mipp, D4Jhu8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16351
HGNC: HGNC:6108
Homologene: 4309
Tssc4
Name: tumor-suppressing subchromosomal transferable fragment 4
Synonyms: ESTM671070
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56844
Homologene: 4169
Taar3
Name: trace amine-associated receptor 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 493809
HGNC: HGNC:4513
Homologene: 117490
Rnf217
Name: ring finger protein 217
Synonyms: Ibrdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 268291
Homologene: 66368
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 54,329,511 bp
  • A to T, chromosome 2 at 53,145,692 bp
  • T to G, chromosome 2 at 67,508,866 bp
  • T to A, chromosome 2 at 75,676,768 bp
  • A to C, chromosome 2 at 129,689,738 bp
  • T to C, chromosome 3 at 57,433,857 bp
  • T to C, chromosome 3 at 59,319,767 bp
  • C to T, chromosome 3 at 95,169,197 bp
  • T to A, chromosome 4 at 3,743,296 bp
  • G to C, chromosome 4 at 56,813,228 bp
  • T to C, chromosome 4 at 84,884,741 bp
  • T to C, chromosome 4 at 116,515,467 bp
  • T to C, chromosome 5 at 90,524,780 bp
  • G to T, chromosome 5 at 111,183,296 bp
  • C to A, chromosome 6 at 77,758,417 bp
  • T to C, chromosome 6 at 124,224,290 bp
  • G to A, chromosome 7 at 103,732,673 bp
  • T to C, chromosome 7 at 122,055,658 bp
  • T to C, chromosome 7 at 143,070,509 bp
  • T to C, chromosome 8 at 12,831,214 bp
  • A to T, chromosome 9 at 45,668,264 bp
  • G to A, chromosome 9 at 57,680,246 bp
  • G to A, chromosome 10 at 3,125,082 bp
  • G to A, chromosome 10 at 18,611,290 bp
  • A to G, chromosome 10 at 23,949,817 bp
  • A to G, chromosome 10 at 31,608,767 bp
  • A to T, chromosome 10 at 42,533,280 bp
  • A to T, chromosome 10 at 58,235,686 bp
  • A to G, chromosome 11 at 8,931,699 bp
  • G to T, chromosome 11 at 21,300,137 bp
  • A to T, chromosome 11 at 59,428,433 bp
  • T to C, chromosome 12 at 79,246,222 bp
  • A to T, chromosome 12 at 118,940,412 bp
  • T to A, chromosome 13 at 41,137,955 bp
  • C to A, chromosome 14 at 54,758,444 bp
  • C to T, chromosome 14 at 64,980,149 bp
  • G to A, chromosome 16 at 27,444,659 bp
  • G to A, chromosome 16 at 32,251,908 bp
  • A to G, chromosome 17 at 30,718,961 bp
  • G to C, chromosome 17 at 37,111,455 bp
  • T to A, chromosome 17 at 74,643,337 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0582 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038772-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.