Strain Name:
C57BL/6J-MtgxR0603Btlr/Mmmh
Stock Number:
038792-MU
Citation ID:
RRID:MMRRC_038792-MU
Other Names:
R0603 (G1), C57BL/6J-MtgxR0603Btlr
Major Collection:

Gene Information

Evl
Name: Ena-vasodilator stimulated phosphoprotein
Synonyms: b2b2600Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14026
VEGA: 12
Homologene: 56752
Uba2
Name: ubiquitin-like modifier activating enzyme 2
Synonyms: Sumo-1 activating enzyme subunit 2, UBA2, anthracycline-associated resistance, Arx, SAE2, Uble1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 50995
Homologene: 4018
Fam117a
Name: family with sequence similarity 117, member A
Synonyms: 5730593F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 215512
Homologene: 12775
Uaca
Name: uveal autoantigen with coiled-coil domains and ankyrin repeats
Synonyms: nucling, 2700059D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72565
VEGA: 9
Homologene: 74297
Pkm
Name: pyruvate kinase, muscle
Synonyms: Pk-3, Pk-2, Pk3, Pkm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18746
VEGA: 9
HGNC: HGNC:9021
Homologene: 37650
Nckap1
Name: NCK-associated protein 1
Synonyms: mh19, Hem-2, H19, Nap1, Hem2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 50884
HGNC: HGNC:7666
Homologene: 8384
Tle1
Name: transducin-like enhancer of split 1
Synonyms: Grg1, Estm14, C230057C06Rik, Tle4l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21885
Homologene: 21058
Caprin1
Name: cell cycle associated protein 1
Synonyms: MMGPIP137, caprin-1, Gpiap1, RNG105
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 53872
HGNC: HGNC:6743
Homologene: 4310
Elp1
Name: elongator complex protein 1
Synonyms: 3110040G09Rik, C78473, IKAP, Ikbkap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230233
HGNC: HGNC:5959
Homologene: 2699
Marf1
Name: meiosis regulator and mRNA stability 1
Synonyms: 4921513D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 223989
VEGA: 16
Homologene: 40967
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: 8430405D05Rik, C130099L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 195018
Homologene: 9027
Anapc7
Name: anaphase promoting complex subunit 7
Synonyms: prediabetic NOD sera-reactive autoantigen, APC7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56317
Homologene: 10512
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Irs4
Name: insulin receptor substrate 4
Synonyms: IRS-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 16370
HGNC: HGNC:6128
Homologene: 137235
Slc6a11
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 11
Synonyms: GAT4, D930045G19Rik, E130202I16Rik, Gabt4, Gat3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243616
Homologene: 129935
Aptx
Name: aprataxin
Synonyms: 2410016G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66408
Homologene: 41634
Kdm4a
Name: lysine (K)-specific demethylase 4A
Synonyms: Jmjd2, D4Ertd222e, JHDM3A, Jmjd2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230674
Homologene: 27780
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269700
Homologene: 28297
Tmem178
Name: transmembrane protein 178
Synonyms: 2810417M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 68027
VEGA: 17
Homologene: 12226
Selenop
Name: selenoprotein P
Synonyms: D15Ucla1, selp, Se-P, Sepp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20363
Homologene: 3945
Nlgn1
Name: neuroligin 1
Synonyms: 6330415N05Rik, NL1, Nlg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 192167
Homologene: 56690
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: tigmin, FPC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Ttc39a
Name: tetratricopeptide repeat domain 39A
Synonyms: 4922503N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230603
Homologene: 17739
Ppp2r1b
Name: protein phosphatase 2, regulatory subunit A, beta
Synonyms: 2410091N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73699
HGNC: HGNC:9303
Homologene: 70244
Gpr158
Name: G protein-coupled receptor 158
Synonyms: 5330427M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241263
Homologene: 19381
Wipi1
Name: WD repeat domain, phosphoinositide interacting 1
Synonyms: 4930533H01Rik, D11Ertd498e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 52639
Homologene: 117983
Col4a2
Name: collagen, type IV, alpha 2
Synonyms: Col4a-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12827
HGNC: HGNC:2203
Homologene: 1390
Disp2
Name: dispatched RND tramsporter family member 2
Synonyms: DispB, B230210L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214240
Homologene: 24916
Mmut
Name: methylmalonyl-Coenzyme A mutase
Synonyms: D230010K02Rik, Mut
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17850
VEGA: 17
HGNC: HGNC:7526
Homologene: 20097
Neto1
Name: neuropilin (NRP) and tolloid (TLL)-like 1
Synonyms: C130005O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 246317
VEGA: 18
Homologene: 16367
Olfr744
Name: olfactory receptor 744
Synonyms: GA_x6K02T2PMLR-6326342-6327313, MOR106-13P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 257884
Homologene: 128063
Srsf9
Name: serine and arginine-rich splicing factor 9
Synonyms: SRp30c, 2610029M16Rik, Sfrs9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 108014
Homologene: 20819
Wdhd1
Name: WD repeat and HMG-box DNA binding protein 1
Synonyms: AND-1, D630024B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218973
Homologene: 56019
Zbbx
Name: zinc finger, B-box domain containing
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213234
Homologene: 11661
Unc5c
Name: unc-5 netrin receptor C
Synonyms: Unc5h3, B130051O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 22253
Homologene: 2765
Asb15
Name: ankyrin repeat and SOCS box-containing 15
Synonyms: 4930400E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 78910
Homologene: 43797
Atp8a1
Name: ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
Synonyms: Atp3a2, B230107D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11980
Homologene: 48402
Wfdc8
Name: WAP four-disulfide core domain 8
Synonyms: LOC277343
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 277343
Homologene: 33799
Zfp956
Name: zinc finger protein 956
Synonyms: AI894139
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 101197
Homologene: 128449
Tchh
Name: trichohyalin
Synonyms: AHF, Thh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99681
Homologene: 136273
Trabd
Name: TraB domain containing
Synonyms: 5730502D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67976
Homologene: 36427
Pgpep1
Name: pyroglutamyl-peptidase I
Synonyms: PGP-I, Pcp, 2810003H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66522
Homologene: 9793
Dzank1
Name: double zinc ribbon and ankyrin repeat domains 1
Synonyms: 2810039F03Rik, Ankrd64, 6330439K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241688
Homologene: 10037
Rsph6a
Name: radial spoke head 6 homolog A (Chlamydomonas)
Synonyms: RSP4, Rshl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 83434
Homologene: 36476
Lmtk3
Name: lemur tyrosine kinase 3
Synonyms: Aatyk3, AATYK3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381983
Homologene: 79449
Tcp11
Name: t-complex protein 11
Synonyms: D17Ken1, Tcp-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21463
Homologene: 8433
Zeb2
Name: zinc finger E-box binding homeobox 2
Synonyms: SIP1, Zfx1b, 9130203F04Rik, D130016B08Rik, Zfhx1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 24136
Homologene: 8868
Lsp1
Name: lymphocyte specific 1
Synonyms: WP34, leukocyte specific protein 1, pp52, p50, leukocyte-specific protein 1, lymphocyte-specific protein 1, Lsp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16985
HGNC: HGNC:6707
Homologene: 1750
Rgs18
Name: regulator of G-protein signaling 18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 64214
Homologene: 11281
Olfr366
Name: olfactory receptor 366
Synonyms: GA_x6K02T2NLDC-33902472-33903401, MOR138-5P, MOR138-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 236509
Homologene: 114744
Olfr1299
Name: olfactory receptor 1299
Synonyms: GA_x6K02T2Q125-72715642-72716580, MOR248-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258886
Homologene: 17426
Olfr58
Name: olfactory receptor 58
Synonyms: IG6, MOR146-7P, GA_x6K02T2PVTD-13523015-13523944, MOR146-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18358
Homologene: 134093
Olfr957
Name: olfactory receptor 957
Synonyms: GA_x6K02T2PVTD-33208209-33207274, MOR171-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258740
VEGA: 9
Nipal2
Name: NIPA-like domain containing 2
Synonyms: 9330161F08Rik, Npal2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223473
VEGA: 15
Homologene: 41586
Gm17732
Name: predicted gene, 17732
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Arhgap4
Name: Rho GTPase activating protein 4
Synonyms: c1, A530015A20Rik, A130009C12Rik, Rgc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 171207
HGNC: HGNC:674
Homologene: 20403
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 20,117,173 bp
  • T to A, chromosome 1 at 144,756,080 bp
  • T to C, chromosome 2 at 21,815,669 bp
  • G to A, chromosome 2 at 37,220,106 bp
  • G to A, chromosome 2 at 45,017,426 bp
  • A to T, chromosome 2 at 80,512,729 bp
  • A to G, chromosome 2 at 103,796,801 bp
  • A to T, chromosome 2 at 111,664,880 bp
  • A to G, chromosome 2 at 118,792,006 bp
  • C to T, chromosome 2 at 144,511,512 bp
  • A to G, chromosome 2 at 164,603,225 bp
  • A to G, chromosome 3 at 25,920,166 bp
  • T to G, chromosome 3 at 75,078,450 bp
  • G to A, chromosome 3 at 93,443,781 bp
  • C to T, chromosome 3 at 141,771,102 bp
  • A to T, chromosome 4 at 40,686,720 bp
  • A to T, chromosome 4 at 56,792,105 bp
  • A to C, chromosome 4 at 72,118,347 bp
  • A to G, chromosome 4 at 109,426,302 bp
  • C to T, chromosome 4 at 118,142,511 bp
  • T to C, chromosome 5 at 67,756,696 bp
  • C to T, chromosome 5 at 115,332,637 bp
  • T to A, chromosome 5 at 121,304,337 bp
  • A to G, chromosome 5 at 122,440,170 bp
  • T to A, chromosome 6 at 24,556,557 bp
  • A to G, chromosome 6 at 47,956,028 bp
  • G to A, chromosome 6 at 114,244,890 bp
  • G to T, chromosome 7 at 19,065,961 bp
  • A to T, chromosome 7 at 34,161,613 bp
  • T to A, chromosome 7 at 45,795,556 bp
  • G to A, chromosome 7 at 142,489,378 bp
  • T to C, chromosome 8 at 11,414,779 bp
  • T to C, chromosome 8 at 70,650,633 bp
  • A to T, chromosome 9 at 19,783,939 bp
  • C to A, chromosome 9 at 39,511,514 bp
  • C to A, chromosome 9 at 50,861,685 bp
  • G to A, chromosome 9 at 54,405,906 bp
  • T to C, chromosome 9 at 59,665,881 bp
  • T to A, chromosome 9 at 60,871,097 bp
  • G to A, chromosome 11 at 72,818,069 bp
  • A to G, chromosome 11 at 95,380,873 bp
  • A to G, chromosome 11 at 109,597,091 bp
  • T to A, chromosome 12 at 108,648,422 bp
  • T to C, chromosome 14 at 47,263,586 bp
  • T to C, chromosome 14 at 50,618,510 bp
  • T to A, chromosome 15 at 3,275,701 bp
  • A to G, chromosome 15 at 34,650,398 bp
  • G to A, chromosome 15 at 89,082,726 bp
  • C to T, chromosome 16 at 14,142,534 bp
  • T to C, chromosome 17 at 28,067,810 bp
  • A to T, chromosome 17 at 40,947,166 bp
  • A to G, chromosome 17 at 80,945,059 bp
  • C to T, chromosome 18 at 62,662,752 bp
  • T to A, chromosome 18 at 86,473,660 bp
  • C to T, chromosome X at 73,906,783 bp
  • T to C, chromosome X at 141,725,075 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0603 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038792-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.