Strain Name:
C57BL/6J-MtgxR0604Btlr/Mmmh
Stock Number:
038793-MU
Citation ID:
RRID:MMRRC_038793-MU
Other Names:
R0604 (G1), C57BL/6J-MtgxR0604Btlr
Major Collection:

Gene Information

Dntt
Name: deoxynucleotidyltransferase, terminal
Synonyms: Tdt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 21673
VEGA: 19
HGNC: HGNC:2983
Homologene: 3014
Suz12
Name: SUZ12 polycomb repressive complex 2 subunit
Synonyms: 2610028O16Rik, D11Ertd530e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 52615
Homologene: 32256
Med1
Name: mediator complex subunit 1
Synonyms: CRSP210, Pparbp, TRAP220, DRIP205, PBP, l11Jus15, TRAP 220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19014
HGNC: HGNC:9234
Homologene: 21002
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 9030205D12Rik, 1810014J18Rik, AD013, A330063D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 109151
Homologene: 11844
Braf
Name: Braf transforming gene
Synonyms: Braf-2, Braf2, 9930012E13Rik, D6Ertd631e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 109880
HGNC: HGNC:1097
Homologene: 3197
Polr3a
Name: polymerase (RNA) III (DNA directed) polypeptide A
Synonyms: 9330175N20Rik, RPC1, RPC155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 218832
VEGA: 14
Homologene: 5124
Tbc1d8
Name: TBC1 domain family, member 8
Synonyms: AD3, GRAM domain, BUB2-like protein 1, HBLP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 54610
Homologene: 31421
Rttn
Name: rotatin
Synonyms: C530033I08Rik, 4921538A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 246102
VEGA: 18
Homologene: 65275
Msr1
Name: macrophage scavenger receptor 1
Synonyms: MRS-A, SR-AII, SR-AI, MSR-A, Scara1, Scvr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20288
HGNC: HGNC:7376
Homologene: 12822
Stim2
Name: stromal interaction molecule 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 116873
Homologene: 32490
Aqr
Name: aquarius
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11834
Homologene: 7629
Fgfr3
Name: fibroblast growth factor receptor 3
Synonyms: sam3, Fgfr-3, HBGFR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14184
HGNC: HGNC:3690
Homologene: 55437
Itsn2
Name: intersectin 2
Synonyms: Ese2, Eh domain, SH3 domain regulator of endocytosis 2, Sh3d1B, Sh3p18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20403
VEGA: 12
HGNC: HGNC:6184
Homologene: 22627
Pard6g
Name: par-6 family cell polarity regulator gamma
Synonyms: 2410049N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93737
VEGA: 18
Homologene: 36487
1700007K13Rik
Name: RIKEN cDNA 1700007K13 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 69327
Homologene: 35416
Sp9
Name: trans-acting transcription factor 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381373
Homologene: 66935
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Mcc
Name: mutated in colorectal cancers
Synonyms: D18Ertd451e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 328949
HGNC: HGNC:6935
Homologene: 20539
Vmn1r69
Name: vomeronasal 1 receptor 69
Synonyms: V1re9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 252904
Homologene: 120153
Gucy2g
Name: guanylate cyclase 2g
Synonyms: GC-G, 2410077I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 73707
Homologene: 44544
Fetub
Name: fetuin beta
Synonyms: 2310011O17Rik, D17980
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 59083
VEGA: 16
HGNC: HGNC:3658
Homologene: 8660
Adrb2
Name: adrenergic receptor, beta 2
Synonyms: beta 2-adrenoceptor, beta 2-AR, Gpcr7, Adrb-2, Badm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 11555
VEGA: 18
HGNC: HGNC:286
Homologene: 30948
Olfr50
Name: olfactory receptor 50
Synonyms: GA_x6K02T2NLDC-33487752-33488690, MOR136-6, ID3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18350
Homologene: 74212
Fam149a
Name: family with sequence similarity 149, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 212326
Homologene: 27540
Ccdc178
Name: coiled coil domain containing 178
Synonyms: 4921528I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 70950
VEGA: 18
Homologene: 12373
Olfr372
Name: olfactory receptor 372
Synonyms: GA_x6K02T2NUPS-191522-192466, MOR282-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 404315
Homologene: 17287
Olfr1179
Name: olfactory receptor 1179
Synonyms: MOR225-2, GA_x6K02T2Q125-49890854-49889931
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258919
Homologene: 74070
Acap1
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Synonyms: Centb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216859
Homologene: 22835
Vmn2r58
Name: vomeronasal 2, receptor 58
Synonyms: EG628422
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 628422
Lats1
Name: large tumor suppressor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16798
VEGA: 10
HGNC: HGNC:6514
Homologene: 55843
1700061G19Rik
Name: RIKEN cDNA 1700061G19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78625
Homologene: 28378
Mtrf1
Name: mitochondrial translational release factor 1
Synonyms: A830062K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 211253
VEGA: 14
HGNC: HGNC:7469
Homologene: 20903
Vwa5b2
Name: von Willebrand factor A domain containing 5B2
Synonyms: EG328644
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 328643
Homologene: 28056
Psg27
Name: pregnancy-specific glycoprotein 27
Synonyms: cea15, EG545925
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 545925
Homologene: 110989
Il1r1
Name: interleukin 1 receptor, type I
Synonyms: IL-1R1, IL-1 receptor alpha chain, Il1r-1, IL-iR, CD121a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16177
HGNC: HGNC:5993
Homologene: 677
Clgn
Name: calmegin
Synonyms: calnexin-t, Cln, A2/6, 4930459O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12745
HGNC: HGNC:2060
Homologene: 68392
Olfr325
Name: olfactory receptor 325
Synonyms: MOR275-5, MOR275-11_p, GA_x6K02T2NKPP-844642-843680
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258261
Homologene: 133015
Gm4952
Name: predicted gene 4952
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240549
Homologene: 72602
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 39,405,326 bp
  • T to C, chromosome 1 at 40,282,246 bp
  • C to A, chromosome 2 at 28,466,091 bp
  • T to A, chromosome 2 at 36,794,107 bp
  • T to A, chromosome 2 at 73,273,638 bp
  • T to C, chromosome 2 at 88,402,383 bp
  • T to C, chromosome 2 at 114,130,604 bp
  • A to T, chromosome 5 at 33,732,782 bp
  • C to T, chromosome 5 at 54,104,584 bp
  • A to G, chromosome 6 at 39,623,697 bp
  • A to G, chromosome 7 at 10,580,654 bp
  • A to T, chromosome 7 at 18,557,072 bp
  • A to G, chromosome 7 at 41,860,576 bp
  • T to C, chromosome 8 at 39,631,268 bp
  • A to G, chromosome 8 at 45,345,008 bp
  • C to T, chromosome 8 at 72,058,400 bp
  • T to C, chromosome 8 at 83,424,194 bp
  • A to G, chromosome 8 at 91,036,542 bp
  • T to A, chromosome 10 at 7,712,661 bp
  • T to A, chromosome 11 at 58,581,348 bp
  • T to C, chromosome 11 at 69,884,625 bp
  • T to C, chromosome 11 at 80,015,243 bp
  • A to C, chromosome 11 at 98,161,050 bp
  • A to C, chromosome 11 at 118,121,471 bp
  • C to A, chromosome 12 at 4,658,189 bp
  • G to A, chromosome 14 at 24,484,164 bp
  • T to C, chromosome 14 at 79,415,887 bp
  • T to A, chromosome 16 at 20,597,015 bp
  • T to C, chromosome 16 at 22,935,660 bp
  • T to A, chromosome 17 at 56,885,169 bp
  • A to G, chromosome 18 at 22,067,443 bp
  • G to A, chromosome 18 at 44,473,756 bp
  • G to A, chromosome 18 at 62,178,515 bp
  • A to G, chromosome 18 at 80,117,208 bp
  • A to G, chromosome 18 at 88,977,758 bp
  • A to G, chromosome 19 at 12,624,672 bp
  • A to G, chromosome 19 at 41,053,149 bp
  • T to A, chromosome 19 at 55,203,087 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0604 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038793-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.