Strain Name:
C57BL/6J-MtgxR0621Btlr/Mmmh
Stock Number:
038810-MU
Citation ID:
RRID:MMRRC_038810-MU
Other Names:
R0621 (G1), C57BL/6J-MtgxR0621Btlr
Major Collection:

Gene Information

Thy1
Name: thymus cell antigen 1, theta
Synonyms: CD90, Thy-1, Thy 1.2, Thy1.1, Thy-1.2, Thy1.2, T25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21838
Homologene: 4580
Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Synonyms: Glyt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 104245
Homologene: 37901
Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: F4/80, DD7A5-7, TM7LN3, EGF-TM7, Ly71, Emr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Acf7, Aclp7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Ptdss2
Name: phosphatidylserine synthase 2
Synonyms: PSS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 27388
Homologene: 8462
Cdc42ep4
Name: CDC42 effector protein (Rho GTPase binding) 4
Synonyms: CEP4, Borg4, 1500041M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 56699
Homologene: 8110
Ddx56
Name: DEAD box helicase 56
Synonyms: 2600001H07Rik, NOH61, D11Ertd619e, DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 52513
Homologene: 6498
Spata5
Name: spermatogenesis associated 5
Synonyms: 2510048F20Rik, Spaf, C78064
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 57815
Homologene: 56920
Kctd3
Name: potassium channel tetramerisation domain containing 3
Synonyms: NY-REN-45, E330032J19Rik, 4930438A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226823
Homologene: 9395
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, Lek1, mitosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21819
Homologene: 2430
Rtf2
Name: replication termination factor 2
Synonyms: 1700067C04Rik, 5730427M17Rik, 2410001C21Rik, Rtfdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66404
Homologene: 9501
Abr
Name: active BCR-related gene
Synonyms: 6330400K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 109934
HGNC: HGNC:81
Homologene: 11081
Wdr62
Name: WD repeat domain 62
Synonyms: 2310038K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233064
Homologene: 15927
Hey2
Name: hairy/enhancer-of-split related with YRPW motif 2
Synonyms: CHF1, Hrt2, Herp1, Hesr2, bHLHb32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 15214
HGNC: HGNC:4881
Homologene: 22705
Fam81a
Name: family with sequence similarity 81, member A
Synonyms: 6430514L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76886
Homologene: 17584
Sos1
Name: SOS Ras/Rac guanine nucleotide exchange factor 1
Synonyms: 4430401P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20662
VEGA: 17
Homologene: 4117
Slc39a11
Name: solute carrier family 39 (metal ion transporter), member 11
Synonyms: 1810074D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69806
Homologene: 12331
Eya3
Name: EYA transcriptional coactivator and phosphatase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14050
HGNC: HGNC:3521
Homologene: 1508
Snx29
Name: sorting nexin 29
Synonyms: LOC381035, LOC385605, 4933437K13Rik, Gm11170, Rundc2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74478
Homologene: 32706
Tle3
Name: transducin-like enhancer of split 3
Synonyms: Grg3b, Grg3a, ESG, 2610103N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21887
Homologene: 21059
Erbb3
Name: erb-b2 receptor tyrosine kinase 3
Synonyms: Erbb-3, Erbb3r, HER3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13867
HGNC: HGNC:3431
Homologene: 20457
Efnb3
Name: ephrin B3
Synonyms: Elk-L3, Epl8, LERK-8, ELF-3, EFL-6, NLERK-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13643
HGNC: HGNC:3228
Homologene: 1076
Gnb4
Name: guanine nucleotide binding protein (G protein), beta 4
Synonyms: 6720453A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14696
Homologene: 69140
Dctn2
Name: dynactin 2
Synonyms: RBP50, DCTN-50, p50, 2310042E05Rik, C130077D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 69654
VEGA: 10
HGNC: HGNC:2712
Homologene: 4667
Ddx24
Name: DEAD box helicase 24
Synonyms: 2510027P10Rik, 1700055J08Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 27225
VEGA: 12
Homologene: 10702
Zfp597
Name: zinc finger protein 597
Synonyms: 4933407K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 71063
Homologene: 33641
Caprin2
Name: caprin family member 2
Synonyms: Eeg1, C1qdc1, RNG140
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232560
Homologene: 11393
Siglec1
Name: sialic acid binding Ig-like lectin 1, sialoadhesin
Synonyms: CD169, Siglec-1, Sn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20612
Homologene: 124458
Myh13
Name: myosin, heavy polypeptide 13, skeletal muscle
Synonyms: extraocular myosin, EO Myosin, MyHC-eo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 544791
HGNC: HGNC:7571
Homologene: 55780
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244484
Homologene: 12460
Armc3
Name: armadillo repeat containing 3
Synonyms: 4921513G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70882
Homologene: 31589
Ttc21b
Name: tetratricopeptide repeat domain 21B
Synonyms: 2410066K11Rik, line 158, Thm1, aln
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 73668
Homologene: 57006
AC165146.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Hoxb3
Name: homeobox B3
Synonyms: Hox-2.7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15410
HGNC: HGNC:5114
Homologene: 1617
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: EG235580, 1110001D15Rik, Dvwa, Vwa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68553
Homologene: 130754
Nos1ap
Name: nitric oxide synthase 1 (neuronal) adaptor protein
Synonyms: 6330408P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70729
Homologene: 135990
Olfr1250
Name: olfactory receptor 1250
Synonyms: GA_x6K02T2Q125-51098877-51097933, MOR231-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258967
Homologene: 128094
Kif26b
Name: kinesin family member 26B
Synonyms: N-11 kinesin, D230039L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269152
Homologene: 18623
Dsg1c
Name: desmoglein 1 gamma
Synonyms: Dsg6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 211924
HGNC: HGNC:3048
Lipo2
Name: lipase, member O2
Synonyms: Gm8981
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 101055671
Homologene: 103863
Olfr746
Name: olfactory receptor 746
Synonyms: GA_x6K02T2PMLR-6372116-6373060, MOR106-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258295
Homologene: 134081
Alyref
Name: Aly/REF export factor
Synonyms: REF1, Refbp1, Thoc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21681
Homologene: 38099
Atxn7l1
Name: ataxin 7-like 1
Synonyms: 2810423G08Rik, Atxn7l4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 380753
Homologene: 53366
Vmn2r107
Name: vomeronasal 2, receptor 107
Synonyms: V2r6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22312
Homologene: 129750
Ppm1f
Name: protein phosphatase 1F (PP2C domain containing)
Synonyms: 4933427B07Rik, 1110021B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 68606
Homologene: 22828
Foxf1
Name: forkhead box F1
Synonyms: FREAC1, Hfh8, Freac-1, HFH-8, Foxf1, Foxf1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 15227
HGNC: HGNC:3809
Homologene: 1114
St8sia6
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
Synonyms: ST8Sia VI, 1700007J08Rik, Siat8f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241230
Homologene: 17112
Pde3a
Name: phosphodiesterase 3A, cGMP inhibited
Synonyms: A930022O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54611
HGNC: HGNC:8778
Homologene: 708
Klhl30
Name: kelch-like 30
Synonyms: 4631423F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70788
Homologene: 18891
Aph1b
Name: aph1 homolog B, gamma secretase subunit
Synonyms: 2310057K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208117
Homologene: 12844
Olfr418
Name: olfactory receptor 418
Synonyms: GA_x6K02T2P20D-20826777-20827719, GA_x6K02T2R7CC-581296-580364, MOR267-12P, MOR267-8, Olfr1403, Olfr418-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258645
HGNC: HGNC:8175
Homologene: 8218
Gtf2h2
Name: general transcription factor II H, polypeptide 2
Synonyms: Btf2p44, basal transcription factor 2, p44 subunit, 44kDa, p44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 23894
Homologene: 1159
C1s2
Name: complement component 1, s subcomponent 2
Synonyms: Gm5077
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 317677
HGNC: HGNC:1247
Homologene: 1314
Ccdc183
Name: coiled-coil domain containing 183
Synonyms: Cccd183, 4921530D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77058
Homologene: 50023
Snph
Name: syntaphilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241727
Homologene: 8817
C130073F10Rik
Name: RIKEN cDNA C130073F10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242574
Sh2d5
Name: SH2 domain containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230863
Homologene: 20002
Ankrd40
Name: ankyrin repeat domain 40
Synonyms: 5530600A18Rik, Gcap15, 1110011C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71452
Homologene: 12393
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 91,357,863 bp
  • T to C, chromosome 1 at 170,318,581 bp
  • C to T, chromosome 1 at 173,270,675 bp
  • C to G, chromosome 1 at 178,915,653 bp
  • C to T, chromosome 1 at 188,981,341 bp
  • T to C, chromosome 1 at 189,672,628 bp
  • T to A, chromosome 2 at 13,657,282 bp
  • A to T, chromosome 2 at 19,295,393 bp
  • T to A, chromosome 2 at 25,615,518 bp
  • C to T, chromosome 2 at 66,226,011 bp
  • C to A, chromosome 2 at 89,657,115 bp
  • G to A, chromosome 2 at 131,074,268 bp
  • C to T, chromosome 2 at 151,593,722 bp
  • C to A, chromosome 2 at 172,466,296 bp
  • C to T, chromosome 3 at 32,591,207 bp
  • C to T, chromosome 3 at 37,432,029 bp
  • A to G, chromosome 4 at 101,890,795 bp
  • T to C, chromosome 4 at 123,380,534 bp
  • T to G, chromosome 4 at 132,694,802 bp
  • T to C, chromosome 4 at 138,258,318 bp
  • A to T, chromosome 6 at 124,631,112 bp
  • T to C, chromosome 6 at 141,249,999 bp
  • A to T, chromosome 6 at 148,858,678 bp
  • T to C, chromosome 7 at 30,254,061 bp
  • G to A, chromosome 7 at 49,917,365 bp
  • T to C, chromosome 7 at 141,147,078 bp
  • C to A, chromosome 8 at 54,643,191 bp
  • T to C, chromosome 8 at 121,085,180 bp
  • T to A, chromosome 9 at 44,046,733 bp
  • T to A, chromosome 9 at 61,410,105 bp
  • A to T, chromosome 9 at 66,779,334 bp
  • G to T, chromosome 9 at 70,093,647 bp
  • A to T, chromosome 9 at 106,066,791 bp
  • T to A, chromosome 10 at 30,834,386 bp
  • T to C, chromosome 10 at 127,277,940 bp
  • T to C, chromosome 10 at 128,586,225 bp
  • A to G, chromosome 11 at 6,266,303 bp
  • A to C, chromosome 11 at 67,341,232 bp
  • T to C, chromosome 11 at 69,555,972 bp
  • T to C, chromosome 11 at 76,509,072 bp
  • A to G, chromosome 11 at 94,339,607 bp
  • A to T, chromosome 11 at 96,345,963 bp
  • G to A, chromosome 11 at 113,464,079 bp
  • G to A, chromosome 11 at 113,728,696 bp
  • A to G, chromosome 11 at 120,595,333 bp
  • T to C, chromosome 12 at 33,326,100 bp
  • T to C, chromosome 12 at 103,425,558 bp
  • A to T, chromosome 13 at 100,488,925 bp
  • G to A, chromosome 14 at 19,402,011 bp
  • G to A, chromosome 14 at 50,653,962 bp
  • T to C, chromosome 15 at 66,773,496 bp
  • A to G, chromosome 16 at 3,866,364 bp
  • A to G, chromosome 16 at 11,405,787 bp
  • G to A, chromosome 16 at 16,915,308 bp
  • A to T, chromosome 17 at 20,374,990 bp
  • T to A, chromosome 17 at 57,441,359 bp
  • A to G, chromosome 17 at 80,451,979 bp
  • C to A, chromosome 18 at 20,279,695 bp
  • C to T, chromosome 19 at 33,730,939 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0621 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038810-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.