Strain Name:
C57BL/6J-MtgxR0635Btlr/Mmmh
Stock Number:
038824-MU
Citation ID:
RRID:MMRRC_038824-MU
Other Names:
R0635 (G1), C57BL/6J-MtgxR0635Btlr
Major Collection:

Gene Information

Hdgfl2
Name: HDGF like 2
Synonyms: HRP-2, Hdgfrp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15193
VEGA: 17
Homologene: 7355
Pik3r1
Name: phosphoinositide-3-kinase regulatory subunit 1
Synonyms: p85alpha, p50alpha, p55alpha, PI3K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18708
HGNC: HGNC:8979
Homologene: 7889
Mt1
Name: metallothionein 1
Synonyms: MT-I, Mt-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 17748
Pik3cb
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Synonyms: 1110001J02Rik, p110beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74769
HGNC: HGNC:8976
Homologene: 21250
Il21r
Name: interleukin 21 receptor
Synonyms: NILR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 60504
HGNC: HGNC:6006
Homologene: 11040
Oxtr
Name: oxytocin receptor
Synonyms: OTR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18430
HGNC: HGNC:8529
Homologene: 20255
Pcm1
Name: pericentriolar material 1
Synonyms: 9430077F19Rik, 2600002H09Rik, C030044G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Cep290
Name: centrosomal protein 290
Synonyms: Nphp6, b2b1454Clo, b2b1752Clo, Kiaa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216274
VEGA: 10
Homologene: 77213
Pcnt
Name: pericentrin (kendrin)
Synonyms: Pcnt2, m275Asp, m239Asp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18541
VEGA: 10
Dmxl1
Name: Dmx-like 1
Synonyms: C630007L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240283
HGNC: HGNC:2937
Homologene: 21136
Nusap1
Name: nucleolar and spindle associated protein 1
Synonyms: 2610201A12Rik, NuSAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 108907
Homologene: 10207
Tead1
Name: TEA domain family member 1
Synonyms: mTEF-1, TEF-1, TEAD-1, Tcf13, Gtrgeo5, B230114H05Rik, 2610024B07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21676
Homologene: 2418
Ncapd2
Name: non-SMC condensin I complex, subunit D2
Synonyms: CNAP1, CAP-D2, 2810406C15Rik, 2810465G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 68298
Homologene: 6497
Cntnap1
Name: contactin associated protein-like 1
Synonyms: p190, Caspr, Nrxn4, NCP1, paranodin, shm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53321
HGNC: HGNC:8011
Homologene: 2693
Mgat4a
Name: mannoside acetylglucosaminyltransferase 4, isoenzyme A
Synonyms: GnT-IVa, 9530018I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269181
HGNC: HGNC:7047
Homologene: 8153
Rreb1
Name: ras responsive element binding protein 1
Synonyms: 1110037N09Rik, B930013M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68750
Homologene: 2218
Il2ra
Name: interleukin 2 receptor, alpha chain
Synonyms: IL-2R alpha chain, CD25, Ly-43, Il2r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16184
HGNC: HGNC:6008
Homologene: 360
Ppa1
Name: pyrophosphatase (inorganic) 1
Synonyms: 2010317E03Rik, Pyp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67895
HGNC: HGNC:9226
Homologene: 5356
Glg1
Name: golgi apparatus protein 1
Synonyms: ESL-1, CFR, MG-160, MG160, CFR-1, Selel
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20340
HGNC: HGNC:4316
Homologene: 7533
Zfp398
Name: zinc finger protein 398
Synonyms: 5730513I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 272347
Homologene: 12358
Nol8
Name: nucleolar protein 8
Synonyms: 4921532D18Rik, D13Ertd548e, 5730412B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 70930
VEGA: 13
Homologene: 41210
Ift43
Name: intraflagellar transport 43
Synonyms: 1700019E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76411
VEGA: 12
Homologene: 12641
Ubxn7
Name: UBX domain protein 7
Synonyms: Ubxd7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224111
VEGA: 16
Homologene: 45585
Prss22
Name: protease, serine 22
Synonyms: SP001LA, BSSP-4, 4733401N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70835
VEGA: 17
Homologene: 23344
Zfp808
Name: zinc finger protein 808
Synonyms: Gm7036
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 630579
Homologene: 134631
Armh4
Name: armadillo-like helical domain containing 4
Synonyms: 3632451O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67419
Homologene: 12127
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: lrd, b2b1203Clo, b2b1279Clo, b2b598Clo, b2b1289Clo, b2b1727Clo, Dnahc11, avc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Sema6b
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
Synonyms: VIb, semaZ, Sema, Seman
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20359
VEGA: 17
Homologene: 8428
Slc4a1
Name: solute carrier family 4 (anion exchanger), member 1
Synonyms: erythrocyte membrane protein band 3, band 3, Empb3, Ae1, CD233, l11Jus51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20533
Homologene: 133556
Vmn2r116
Name: vomeronasal 2, receptor 116
Synonyms: EG619697, V2Rp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 619697
Homologene: 86604
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Specc1
Name: sperm antigen with calponin homology and coiled-coil domains 1
Synonyms: 2810012G08Rik, B230396K10Rik, Cytsb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432572
Homologene: 45157
Vmn2r77
Name: vomeronasal 2, receptor 77
Synonyms: EG546983
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546983
Homologene: 115466
Morc2b
Name: microrchidia 2B
Synonyms: 4932411A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240069
Homologene: 18615
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Col6a5, Gm7455
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 665033
Homologene: 122792
Adamts15
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235130
VEGA: 9
Homologene: 8610
Vmn2r98
Name: vomeronasal 2, receptor 98
Synonyms: EG224552
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224552
Homologene: 115024
Snx19
Name: sorting nexin 19
Synonyms: 3526401K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102607
VEGA: 9
Homologene: 8846
Lao1
Name: L-amino acid oxidase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100470
Homologene: 44223
Olfr495
Name: olfactory receptor 495
Synonyms: GA_x6K02T2PBJ9-10725148-10726140, MOR204-37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258361
Homologene: 133600
Adgrb1
Name: adhesion G protein-coupled receptor B1
Synonyms: B830018M07Rik, Bai1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 107831
HGNC: HGNC:943
Homologene: 1287
Rgr
Name: retinal G protein coupled receptor
Synonyms: RGR opsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 57811
VEGA: 14
HGNC: HGNC:9990
Homologene: 37709
Nrm
Name: nurim (nuclear envelope membrane protein)
Synonyms: 2610307M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106582
HGNC: HGNC:8003
Homologene: 38294
Fam71a
Name: family with sequence similarity 71, member A
Synonyms: 4933417M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 619288
Homologene: 77474
Chil5
Name: chitinase-like 5
Synonyms: Bclp2, Bclp1, Chi3l7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229687
Homologene: 132668
Lrrcc1
Name: leucine rich repeat and coiled-coil domain containing 1
Synonyms: 4932441F23Rik, 1200008A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71710
Homologene: 12559
Daxx
Name: Fas death domain-associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13163
HGNC: HGNC:2681
Homologene: 1033
Hrh1
Name: histamine receptor H1
Synonyms: Bphs, Hir
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 15465
HGNC: HGNC:5182
Homologene: 668
Scel
Name: sciellin
Synonyms: 9230114I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 64929
VEGA: 14
Homologene: 2850
Adamts17
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
Synonyms: AU023434
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233332
Homologene: 16373
5730455P16Rik
Name: RIKEN cDNA 5730455P16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70591
Homologene: 11177
Gm17333
Name: predicted gene, 17333
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Phka1
Name: phosphorylase kinase alpha 1
Synonyms: Phka, 9830108K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 18679
HGNC: HGNC:8925
Homologene: 1981
Paip2b
Name: poly(A) binding protein interacting protein 2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232164
Homologene: 25798
Timm10b
Name: translocase of inner mitochondrial membrane 10B
Synonyms: Fracture Callus 1, FxC1, Tim10b, Tim9b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14356
HGNC: HGNC:4022
Homologene: 8142
Gm10272
Name: predicted gene 10272
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16697
VEGA: 10
Nkd2
Name: naked cuticle 2
Synonyms: 2210403L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72293
Homologene: 12459
Ocln
Name: occludin
Synonyms: Ocl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18260
HGNC: HGNC:8104
Homologene: 1905
Mipep
Name: mitochondrial intermediate peptidase
Synonyms: 5730405E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 70478
VEGA: 14
HGNC: HGNC:7104
Homologene: 4337
Haao
Name: 3-hydroxyanthranilate 3,4-dioxygenase
Synonyms: 0610007K21Rik, 0610012J07Rik, 3-HAO, 3HAO, 3-HAOxase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 107766
VEGA: 17
HGNC: HGNC:4796
Homologene: 8148
Marchf5
Name: membrane associated ring-CH-type finger 5
Synonyms: 2310008I22Rik, E130202O05Rik, 1810015H18Rik, MARCH-V, 2700055A20Rik, Rnf153, 5730499H23Rik, MITOL, March5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 69104
Homologene: 9862
Mageb5
Name: MAGE family member B5
Synonyms: mMage-b5, 1700056A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 74271
Homologene: 135943
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 37,452,294 bp
  • A to T, chromosome 1 at 90,808,086 bp
  • T to C, chromosome 1 at 191,163,727 bp
  • C to T, chromosome 2 at 11,680,366 bp
  • A to G, chromosome 2 at 119,627,667 bp
  • G to A, chromosome 3 at 14,559,228 bp
  • A to T, chromosome 3 at 106,017,203 bp
  • C to T, chromosome 4 at 118,968,296 bp
  • T to C, chromosome 6 at 47,863,140 bp
  • T to C, chromosome 6 at 83,809,909 bp
  • A to G, chromosome 6 at 112,489,200 bp
  • T to C, chromosome 6 at 114,480,145 bp
  • A to G, chromosome 6 at 125,173,036 bp
  • T to C, chromosome 7 at 66,908,605 bp
  • T to A, chromosome 7 at 86,811,175 bp
  • A to C, chromosome 7 at 105,640,688 bp
  • T to A, chromosome 7 at 108,395,764 bp
  • T to C, chromosome 7 at 112,891,706 bp
  • T to C, chromosome 7 at 125,632,506 bp
  • T to A, chromosome 8 at 41,267,179 bp
  • A to T, chromosome 8 at 94,179,821 bp
  • A to G, chromosome 8 at 111,163,764 bp
  • C to A, chromosome 9 at 30,428,810 bp
  • T to G, chromosome 9 at 30,428,811 bp
  • A to G, chromosome 9 at 30,904,770 bp
  • A to G, chromosome 9 at 99,064,218 bp
  • G to A, chromosome 9 at 105,928,606 bp
  • A to G, chromosome 10 at 61,665,440 bp
  • A to G, chromosome 10 at 61,666,970 bp
  • T to C, chromosome 10 at 76,404,585 bp
  • G to A, chromosome 10 at 77,706,701 bp
  • A to G, chromosome 10 at 100,492,676 bp
  • G to A, chromosome 11 at 62,118,903 bp
  • A to T, chromosome 11 at 80,374,065 bp
  • A to G, chromosome 11 at 101,183,459 bp
  • T to C, chromosome 11 at 102,352,672 bp
  • T to A, chromosome 12 at 86,085,081 bp
  • A to G, chromosome 12 at 118,007,996 bp
  • A to T, chromosome 13 at 37,941,564 bp
  • C to G, chromosome 13 at 49,676,758 bp
  • T to A, chromosome 13 at 62,172,419 bp
  • T to C, chromosome 13 at 73,826,894 bp
  • T to A, chromosome 13 at 100,506,236 bp
  • C to T, chromosome 13 at 101,757,418 bp
  • T to A, chromosome 14 at 37,038,947 bp
  • A to G, chromosome 14 at 49,773,143 bp
  • G to A, chromosome 14 at 60,829,390 bp
  • T to A, chromosome 14 at 103,583,139 bp
  • C to A, chromosome 15 at 74,540,892 bp
  • T to A, chromosome 16 at 32,367,417 bp
  • AAGAAGAGAAGAGAAGAGAAGAGAAGAGAAGAGAA to AAGAAGAGAAGAGAAGAGAAGAGAAGAGAAGAGAAGAGAA, chromosome 16 at 77,852,878 bp
  • T to C, chromosome 17 at 19,080,497 bp
  • T to A, chromosome 17 at 23,386,887 bp
  • T to A, chromosome 17 at 23,996,688 bp
  • A to T, chromosome 17 at 33,137,687 bp
  • T to A, chromosome 17 at 33,912,644 bp
  • C to A, chromosome 17 at 35,864,264 bp
  • T to A, chromosome 17 at 56,096,057 bp
  • A to G, chromosome 17 at 56,129,971 bp
  • A to G, chromosome 17 at 83,838,574 bp
  • T to C, chromosome 18 at 49,851,423 bp
  • A to T, chromosome 19 at 37,220,408 bp
  • T to A, chromosome X at 91,779,993 bp
  • G to A, chromosome X at 102,621,400 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
(Deceased) Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0635 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038824-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.