Strain Name:
C57BL/6J-MtgxR0667Btlr/Mmmh
Stock Number:
038852-MU
Citation ID:
RRID:MMRRC_038852-MU
Other Names:
R0667 (G1), C57BL/6J-MtgxR0667Btlr
Major Collection:

Gene Information

Satb1
Name: special AT-rich sequence binding protein 1
Synonyms: 2610306G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20230
Homologene: 2232
Scn3a
Name: sodium channel, voltage-gated, type III, alpha
Synonyms: LOC381367, Nav1.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20269
Homologene: 56005
Tjp2
Name: tight junction protein 2
Synonyms: ZO-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 21873
VEGA: 19
Homologene: 3541
Sae1
Name: SUMO1 activating enzyme subunit 1
Synonyms: 2400010M20Rik, Uble1a, D7Ertd177e, HSPC140, SUMO-1 activating enzyme subunit 1, 2610044L12Rik, AOS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56459
Homologene: 4019
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320528
VEGA: 9
Homologene: 41188
Kansl1
Name: KAT8 regulatory NSL complex subunit 1
Synonyms: 1700081L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76719
Homologene: 9140
Ttc5
Name: tetratricopeptide repeat domain 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219022
VEGA: 14
Homologene: 14397
Mtf2
Name: metal response element binding transcription factor 2
Synonyms: 9230112N11Rik, Pcl2, M96, C76717
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17765
Homologene: 7207
Nufip2
Name: nuclear fragile X mental retardation protein interacting protein 2
Synonyms: 9530056D24Rik, 1110001M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 68564
Homologene: 10808
Prmt3
Name: protein arginine N-methyltransferase 3
Synonyms: 2010005E20Rik, Hrmt1l3, 2410018A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 71974
Homologene: 24255
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10, D16Ium10e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 21844
Homologene: 2443
Piwil1
Name: piwi-like RNA-mediated gene silencing 1
Synonyms: MIWI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 57749
HGNC: HGNC:9007
Homologene: 37963
Uhrf1
Name: ubiquitin-like, containing PHD and RING finger domains, 1
Synonyms: ICBP90, Np95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18140
Homologene: 7866
Cand1
Name: cullin associated and neddylation disassociated 1
Synonyms: 2310038O07Rik, D10Ertd516e, 6330512O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71902
Homologene: 10202
Pabpc1
Name: poly(A) binding protein, cytoplasmic 1
Synonyms: Pabpl1, Pabp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18458
HGNC: HGNC:8554
Homologene: 37638
Setd1a
Name: SET domain containing 1A
Synonyms: KMT2F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233904
Homologene: 52251
Adamts12
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239337
VEGA: 15
Homologene: 12808
Dsg2
Name: desmoglein 2
Synonyms: D18Ertd293e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13511
HGNC: HGNC:3049
Homologene: 1464
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4933421G18Rik, 4921518A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 71175
VEGA: 15
Homologene: 15850
Atad2
Name: ATPase family, AAA domain containing 2
Synonyms: 2610509G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 70472
VEGA: 15
Homologene: 6044
Mgme1
Name: mitochondrial genome maintenance exonuclease 1
Synonyms: 8430406I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74528
Homologene: 12573
Cep76
Name: centrosomal protein 76
Synonyms: 6230425F05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225659
VEGA: 18
Homologene: 11774
Lama2
Name: laminin, alpha 2
Synonyms: mer, merosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Pld1
Name: phospholipase D1
Synonyms: Pld1a, Pld1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18805
HGNC: HGNC:9067
Homologene: 116234
Ptprd
Name: protein tyrosine phosphatase, receptor type, D
Synonyms: 3000002J10Rik, B230219D21Rik, 1110002J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 19266
HGNC: HGNC:9668
Gm5901
Name: predicted gene 5901
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100503879
Homologene: 18311
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Avl9
Name: AVL9 cell migration associated
Synonyms: 5830411G16Rik, D730049P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 78937
Homologene: 62425
Mylk3
Name: myosin light chain kinase 3
Synonyms: D830007F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 213435
Homologene: 35278
Ppfia2
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
Synonyms: Liprin-alpha2, E130120L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 327814
VEGA: 10
HGNC: HGNC:9246
Homologene: 27953
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Scn2a
Name: sodium channel, voltage-gated, type II, alpha
Synonyms: Nav1.2, A230052E19Rik, Scn2a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 110876
Homologene: 75001
5830411N06Rik
Name: RIKEN cDNA 5830411N06 gene
Synonyms: Scart2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244234
Homologene: 133218
Vmn2r93
Name: vomeronasal 2, receptor 93
Synonyms: EG627132
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627132
Homologene: 129750
Slc8a1
Name: solute carrier family 8 (sodium/calcium exchanger), member 1
Synonyms: Ncx1, D930008O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20541
VEGA: 17
Homologene: 69090
Myo1c
Name: myosin IC
Synonyms: C80397, myosin-Ibeta, mm1beta, myr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
Zmynd15
Name: zinc finger, MYND-type containing 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 574428
Homologene: 12995
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: Dvwa, Vwa6, EG235580, 1110001D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 68553
Homologene: 130754
Abca5
Name: ATP-binding cassette, sub-family A (ABC1), member 5
Synonyms: ABC13, B930033A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217265
HGNC: HGNC:35
Homologene: 10263
Mep1a
Name: meprin 1 alpha
Synonyms: Mep-1a, Mep-1, Mep1, meprin A alpha-subunit, meprin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17287
HGNC: HGNC:7015
Homologene: 31323
Tgfbr3
Name: transforming growth factor, beta receptor III
Synonyms: TBRIII, 1110036H20Rik, betaglycan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 21814
Homologene: 2436
Osm
Name: oncostatin M
Synonyms: OncoM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18413
HGNC: HGNC:8506
Homologene: 10741
Kcnh1
Name: potassium voltage-gated channel, subfamily H (eag-related), member 1
Synonyms: ether a go-go, Kv10.1, Eag1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16510
HGNC: HGNC:6250
Homologene: 68242
Serpinb9b
Name: serine (or cysteine) peptidase inhibitor, clade B, member 9b
Synonyms: 1600019A21Rik, ovalbumin, Spi10, R86, SPI-CI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20706
HGNC: HGNC:8955
Homologene: 137240
Olfr1239
Name: olfactory receptor 1239
Synonyms: GA_x6K02T2Q125-50861284-50860367, MOR231-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258972
Homologene: 74244
Vmn2r107
Name: vomeronasal 2, receptor 107
Synonyms: V2r6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22312
Homologene: 129750
Plekhg3
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 3
Synonyms: MGC40768
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 263406
VEGA: 12
Homologene: 77478
Tyk2
Name: tyrosine kinase 2
Synonyms: JTK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 54721
VEGA: 9
Homologene: 20712
Hkdc1
Name: hexokinase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216019
Homologene: 128937
Krt31
Name: keratin 31
Synonyms: MKHA-1, Krt1-1, Kha1, Ha1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16660
HGNC: HGNC:6448
Homologene: 74433
Olfr138
Name: olfactory receptor 138
Synonyms: MOR256-40P, GA_x6K02T2PSCP-2718585-2719523, Olfr89
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 170648
Homologene: 119758
Cd200
Name: CD200 antigen
Synonyms: MRC OX-2, Mox2, OX2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 17470
HGNC: HGNC:7203
Homologene: 4344
Prr36
Name: proline rich 36
Synonyms: BC068157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 73072
Homologene: 136398
Olfr855
Name: olfactory receptor 855
Synonyms: GA_x6K02T2PVTD-13330461-13331399, MOR148-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258517
Homologene: 74176
Zfp456
Name: zinc finger protein 456
Synonyms: Rslcan-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 408065
Homologene: 110878
Zhx1
Name: zinc fingers and homeoboxes 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 22770
Homologene: 5225
Klhdc3
Name: kelch domain containing 3
Synonyms: 1300011D16Rik, Peas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 71765
VEGA: 17
Homologene: 14290
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 90,828,101 bp
  • T to A, chromosome 1 at 192,506,038 bp
  • C to A, chromosome 2 at 65,484,411 bp
  • A to T, chromosome 2 at 65,751,996 bp
  • T to C, chromosome 2 at 89,417,688 bp
  • T to A, chromosome 2 at 144,278,987 bp
  • A to G, chromosome 3 at 28,079,178 bp
  • A to G, chromosome 4 at 75,957,346 bp
  • A to T, chromosome 5 at 107,177,850 bp
  • C to T, chromosome 5 at 108,104,503 bp
  • T to A, chromosome 5 at 128,741,478 bp
  • G to T, chromosome 6 at 56,736,483 bp
  • A to T, chromosome 7 at 16,368,532 bp
  • A to G, chromosome 7 at 49,791,995 bp
  • G to A, chromosome 7 at 105,377,490 bp
  • A to G, chromosome 7 at 127,786,593 bp
  • C to G, chromosome 7 at 140,261,537 bp
  • G to T, chromosome 8 at 4,216,311 bp
  • A to G, chromosome 8 at 85,355,165 bp
  • T to A, chromosome 9 at 19,585,447 bp
  • A to C, chromosome 9 at 21,108,871 bp
  • G to A, chromosome 9 at 67,951,573 bp
  • A to G, chromosome 9 at 79,628,462 bp
  • G to A, chromosome 9 at 106,029,959 bp
  • T to A, chromosome 10 at 27,344,410 bp
  • T to C, chromosome 10 at 62,411,865 bp
  • A to T, chromosome 10 at 106,913,694 bp
  • A to G, chromosome 10 at 119,216,520 bp
  • G to T, chromosome 11 at 4,239,918 bp
  • G to T, chromosome 11 at 70,465,118 bp
  • A to G, chromosome 11 at 75,668,512 bp
  • T to A, chromosome 11 at 77,692,013 bp
  • T to A, chromosome 11 at 100,048,125 bp
  • A to G, chromosome 11 at 104,343,538 bp
  • G to T, chromosome 11 at 110,327,811 bp
  • C to T, chromosome 12 at 76,576,598 bp
  • T to A, chromosome 13 at 33,032,926 bp
  • A to T, chromosome 13 at 67,366,742 bp
  • T to A, chromosome 14 at 50,765,958 bp
  • A to C, chromosome 15 at 8,361,004 bp
  • C to T, chromosome 15 at 11,215,624 bp
  • G to A, chromosome 15 at 36,598,031 bp
  • T to C, chromosome 15 at 58,053,165 bp
  • A to G, chromosome 15 at 58,098,719 bp
  • T to A, chromosome 16 at 45,394,857 bp
  • C to A, chromosome 16 at 89,897,984 bp
  • T to C, chromosome 17 at 18,326,241 bp
  • A to C, chromosome 17 at 20,355,654 bp
  • C to A, chromosome 17 at 38,275,157 bp
  • T to G, chromosome 17 at 43,478,190 bp
  • A to T, chromosome 17 at 46,677,225 bp
  • T to G, chromosome 17 at 51,782,861 bp
  • T to C, chromosome 17 at 56,310,677 bp
  • C to A, chromosome 17 at 81,648,881 bp
  • A to C, chromosome 18 at 20,573,499 bp
  • A to T, chromosome 18 at 67,634,778 bp
  • A to G, chromosome 19 at 24,108,749 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0667 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038852-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.