Strain Name:
C57BL/6J-MtgxR0694Btlr/Mmmh
Stock Number:
038879-MU
Citation ID:
RRID:MMRRC_038879-MU
Other Names:
R0694 (G1), C57BL/6J-MtgxR0694Btlr
Major Collection:

Strain Information

Sulf2
Name: sulfatase 2
Synonyms: 2010004N24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72043
Homologene: 10313
Sema6d
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
Synonyms: 1110067B02Rik, Sema6D-2, Sema6D-4, Sema6D-6, Sema6D-1, Sema6D-5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 214968
Homologene: 16195
Arid4b
Name: AT-rich interaction domain 4B
Synonyms: Rbp1l1, 6330417L24Rik, RBBP1L1, 6720480E17Rik, SAP180, BRCAA1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 94246
Homologene: 12847
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: slip, DNAPDcs, DNA-PKcs, DNA-PK, DOXNPH, XRCC7, dxnph
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Fbxo22
Name: F-box protein 22
Synonyms: 0610033L19Rik, 1600016C16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71999
Homologene: 12433
Glyr1
Name: glyoxylate reductase 1 homolog (Arabidopsis)
Synonyms: 2810419J22Rik, NDF, Npac, 3930401K13Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74022
VEGA: 16
Homologene: 12525
Hus1
Name: HUS1 checkpoint clamp component
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15574
HGNC: HGNC:5309
Homologene: 37932
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: A730020P05Rik, sema, Sema6A-1, VIa, Semaq
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20358
Homologene: 32426
Rbl1
Name: RB transcriptional corepressor like 1
Synonyms: retinoblastoma-like 1 (p107), p107
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19650
HGNC: HGNC:9893
Homologene: 2172
Atp6v1g1
Name: ATPase, H+ transporting, lysosomal V1 subunit G1
Synonyms: lysosomal 13kDa, Atp6g1, Vma10, ATP6J, VAG1, 1810024D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66290
HGNC: HGNC:864
Homologene: 31272
Tnn
Name: tenascin N
Synonyms: tenascin-W, Tnw
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329278
Homologene: 18634
Zfp804a
Name: zinc finger protein 804A
Synonyms: C630007C17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241514
Homologene: 18461
Trpc3
Name: transient receptor potential cation channel, subfamily C, member 3
Synonyms: Trrp3, Trp3, Trcp3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22065
Homologene: 20708
Ptprn2
Name: protein tyrosine phosphatase receptor type N polypeptide 2
Synonyms: IA-2beta, IA-2 beta, 4930425H11Rik, phogrin, PTP-NP
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 19276
HGNC: HGNC:9677
Homologene: 2134
Trim50
Name: tripartite motif-containing 50
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 215061
Homologene: 14548
Fbxo39
Name: F-box protein 39
Synonyms: 1700010H23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 628100
Homologene: 15156
Tlcd5
Name: TLC domain containing 5
Synonyms: LOC235300, Tmem136
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235300
VEGA: 9
Homologene: 72560
Bglap2
Name: bone gamma-carboxyglutamate protein 2
Synonyms: bone Gla protein, OG2, osteocalcin, mOC-B
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12097
HGNC: HGNC:1043
Homologene: 104130
Dsn1
Name: DSN1 homolog, MIS12 kinetochore complex component
Synonyms: 1700022L09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66934
Homologene: 49806
Asb13
Name: ankyrin repeat and SOCS box-containing 13
Synonyms: 2210015B19Rik, 6430573K02Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 142688
Homologene: 11666
Kcna1
Name: potassium voltage-gated channel, shaker-related subfamily, member 1
Synonyms: Shak, Mk-1, Kv1.1, mceph, MBK1, mouse brain potassium channel protein-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16485
HGNC: HGNC:6218
Homologene: 183
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 160,118,616 bp
  • A to G, chromosome 2 at 82,053,804 bp
  • T to C, chromosome 2 at 124,664,041 bp
  • T to C, chromosome 2 at 157,005,869 bp
  • A to G, chromosome 2 at 157,169,860 bp
  • T to C, chromosome 2 at 166,085,791 bp
  • A to T, chromosome 3 at 36,671,555 bp
  • C to T, chromosome 3 at 88,378,416 bp
  • C to T, chromosome 4 at 63,549,993 bp
  • A to T, chromosome 5 at 135,353,545 bp
  • T to C, chromosome 6 at 126,642,245 bp
  • C to T, chromosome 9 at 43,111,626 bp
  • T to A, chromosome 9 at 55,221,139 bp
  • C to T, chromosome 11 at 9,007,531 bp
  • G to A, chromosome 11 at 72,318,469 bp
  • G to T, chromosome 12 at 116,824,355 bp
  • G to T, chromosome 13 at 3,649,480 bp
  • C to T, chromosome 13 at 14,187,834 bp
  • T to C, chromosome 16 at 5,026,560 bp
  • A to T, chromosome 16 at 15,768,637 bp
  • G to A, chromosome 18 at 47,290,045 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0694 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038879-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.