Strain Name:
C57BL/6J-MtgxR0739Btlr/Mmmh
Stock Number:
038920-MU
Citation ID:
RRID:MMRRC_038920-MU
Other Names:
R0739 (G1), C57BL/6J-MtgxR0739Btlr
Major Collection:

Gene Information

Sptan1
Name: spectrin alpha, non-erythrocytic 1
Synonyms: alpha-fodrin, Spna-2, 2610027H02Rik, Spna2, alphaII-spectrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20740
Homologene: 2353
Tm9sf4
Name: transmembrane 9 superfamily member 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99237
Homologene: 21620
Zfp568
Name: zinc finger protein 568
Synonyms: LOC381866, chato
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243905
Homologene: 136307
Zc3h14
Name: zinc finger CCCH type containing 14
Synonyms: 1700016A15Rik, 1010001P15Rik, 2700069A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75553
VEGA: 12
Homologene: 32605
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108989
Homologene: 37753
Sec16a
Name: SEC16 homolog A, endoplasmic reticulum export factor
Synonyms: C230052J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227648
Homologene: 10533
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: A530081C03Rik, Murr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17847
Homologene: 40978
Snrpb2
Name: U2 small nuclear ribonucleoprotein B
Synonyms: 2810052G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20639
Homologene: 37728
Eif2d
Name: eukaryotic translation initiation factor 2D
Synonyms: D1Ertd5e, Lgtn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16865
HGNC: HGNC:6583
Homologene: 38244
Cntn2
Name: contactin 2
Synonyms: Tax, TAG-1, axonin, D130012K04Rik, TAG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21367
HGNC: HGNC:2172
Homologene: 3720
Neo1
Name: neogenin
Synonyms: D930014N22Rik, 2610028H22Rik, Igdcc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18007
VEGA: 9
HGNC: HGNC:7754
Homologene: 1870
Itgb3bp
Name: integrin beta 3 binding protein (beta3-endonexin)
Synonyms: 4930471O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67733
HGNC: HGNC:6157
Homologene: 8617
Psmd2
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
Synonyms: TEG-190, Tex190, 9430095H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21762
HGNC: HGNC:9559
Homologene: 2101
Clmn
Name: calmin
Synonyms: 9330188N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 94040
VEGA: 12
Homologene: 11683
Rhbdf2
Name: rhomboid 5 homolog 2
Synonyms: 4732465I17Rik, Rhbdl6, iRhom2, cub
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217344
Homologene: 11612
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Rbp-3, Irbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Dnah1
Name: dynein, axonemal, heavy chain 1
Synonyms: MDHC7, E030034C22Rik, B230373P09Rik, Dnahc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110084
VEGA: 14
HGNC: HGNC:2940
Homologene: 67131
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Ptpn13
Name: protein tyrosine phosphatase, non-receptor type 13
Synonyms: PTP-BL, Ptpri, PTPL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19249
HGNC: HGNC:9646
Homologene: 7909
Stradb
Name: STE20-related kinase adaptor beta
Synonyms: PRO1038, D1Ucla2, Als2cr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227154
Homologene: 10237
F5
Name: coagulation factor V
Synonyms: Cf-5, Cf5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Pcyt2
Name: phosphate cytidylyltransferase 2, ethanolamine
Synonyms: 1110033E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68671
HGNC: HGNC:8756
Homologene: 2143
Kcnk7
Name: potassium channel, subfamily K, member 7
Synonyms: Mlk3, Knot, Kcnk8, 2310014G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16530
HGNC: HGNC:6282
Homologene: 43131
Klra13-ps
Name: killer cell lectin-like receptor subfamily A, member 13, pseudogene
Synonyms: Ly49M
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16631
Olfr486
Name: olfactory receptor 486
Synonyms: GA_x6K02T2PBJ9-10501920-10500976, MOR204-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258489
Homologene: 110483
Parvg
Name: parvin, gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 64099
Homologene: 11151
Atp2a1
Name: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Synonyms: SERCA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11937
HGNC: HGNC:811
Homologene: 7635
Syne4
Name: spectrin repeat containing, nuclear envelope family member 4
Synonyms: 0610012K07Rik, AI428936, nesprin-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233066
Homologene: 17716
Osgepl1
Name: O-sialoglycoprotein endopeptidase-like 1
Synonyms: MGC13061, 2610001M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72085
Homologene: 5561
Tmprss15
Name: transmembrane protease, serine 15
Synonyms: enteropeptidase, enterokinase, A130097D21Rik, Prss7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19146
HGNC: HGNC:9490
Homologene: 2075
Gm20425
Name: predicted gene 20425
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: Cav2.3, Cchra1, alpha1E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
Gabrr1
Name: gamma-aminobutyric acid (GABA) C receptor, subunit rho 1
Synonyms: GABA-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14408
HGNC: HGNC:4090
Homologene: 20470
Pou3f2
Name: POU domain, class 3, transcription factor 2
Synonyms: Brn-2, Brn2, Otf7, 9430075J19Rik, A230098E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18992
HGNC: HGNC:9215
Homologene: 4095
Serpina3f
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3F
Synonyms: 2A1, antitrypsin, alpha-1 antiproteinasin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238393
HGNC: HGNC:16
Homologene: 115927
Axdnd1
Name: axonemal dynein light chain domain containing 1
Synonyms: LOC381304, 9430070O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 77352
Homologene: 52328
Olfr611
Name: olfactory receptor 611
Synonyms: GA_x6K02T2PBJ9-6236637-6235666, MOR15-4, MOR15-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258722
Homologene: 79675
Adcy6
Name: adenylate cyclase 6
Synonyms: AC6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11512
VEGA: 15
HGNC: HGNC:237
Homologene: 22400
Spopfm1
Name: speckle-type BTB/POZ protein family member 1
Synonyms: Gm4778
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 212727
Foxn1
Name: forkhead box N1
Synonyms: whn, Hfh11, D11Bhm185e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15218
Homologene: 2664
Slc22a23
Name: solute carrier family 22, member 23
Synonyms: 3110004L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 73102
Homologene: 41457
Olfr561
Name: olfactory receptor 561
Synonyms: GA_x6K02T2PBJ9-5491151-5492095, MOR14-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259096
Homologene: 133029
Klf11
Name: Kruppel-like factor 11
Synonyms: Tieg2b, D12Ertd427e, Tieg2, Tieg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 194655
Homologene: 2668
Elovl4
Name: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83603
Homologene: 41488
Ankmy1
Name: ankyrin repeat and MYND domain containing 1
Synonyms: 4930483I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241158
Homologene: 9561
D6Ertd527e
Name: DNA segment, Chr 6, ERATO Doi 527, expressed
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 52372
Ccr8
Name: chemokine (C-C motif) receptor 8
Synonyms: Cmkbr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12776
VEGA: 9
HGNC: HGNC:1609
Homologene: 21080
Gdf2
Name: growth differentiation factor 2
Synonyms: Bmp9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12165
VEGA: 14
HGNC: HGNC:4217
Homologene: 32299
Smyd2
Name: SET and MYND domain containing 2
Synonyms: Zmynd14, 1110020E07Rik, KMT3C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226830
Homologene: 32466
Nexmif
Name: neurite extension and migration factor
Synonyms: Xpn, C77370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 245555
Homologene: 19589
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 53,323,195 bp
  • T to A, chromosome 1 at 58,977,015 bp
  • T to C, chromosome 1 at 92,888,648 bp
  • A to G, chromosome 1 at 131,154,363 bp
  • T to A, chromosome 1 at 132,529,012 bp
  • C to T, chromosome 1 at 150,407,497 bp
  • C to T, chromosome 1 at 154,442,278 bp
  • T to C, chromosome 1 at 156,380,886 bp
  • G to C, chromosome 1 at 164,198,917 bp
  • T to C, chromosome 1 at 189,888,862 bp
  • A to T, chromosome 2 at 26,441,051 bp
  • A to T, chromosome 2 at 30,013,518 bp
  • T to C, chromosome 2 at 125,367,630 bp
  • T to A, chromosome 2 at 143,065,361 bp
  • C to A, chromosome 2 at 153,203,814 bp
  • A to G, chromosome 3 at 94,265,795 bp
  • T to C, chromosome 4 at 22,486,960 bp
  • T to C, chromosome 4 at 33,162,781 bp
  • T to C, chromosome 4 at 99,802,196 bp
  • T to C, chromosome 5 at 103,575,132 bp
  • C to G, chromosome 6 at 87,111,668 bp
  • G to A, chromosome 6 at 130,301,305 bp
  • T to A, chromosome 7 at 30,023,321 bp
  • C to A, chromosome 7 at 30,317,145 bp
  • T to C, chromosome 7 at 102,774,665 bp
  • T to C, chromosome 7 at 103,517,724 bp
  • T to C, chromosome 7 at 108,172,010 bp
  • T to C, chromosome 7 at 126,448,256 bp
  • C to T, chromosome 9 at 58,921,877 bp
  • A to G, chromosome 9 at 83,785,109 bp
  • A to T, chromosome 9 at 103,197,595 bp
  • G to A, chromosome 9 at 120,094,349 bp
  • C to T, chromosome 11 at 23,467,243 bp
  • T to C, chromosome 11 at 78,358,999 bp
  • A to T, chromosome 11 at 116,600,161 bp
  • A to G, chromosome 11 at 120,612,044 bp
  • T to C, chromosome 12 at 24,660,248 bp
  • T to A, chromosome 12 at 98,757,201 bp
  • T to C, chromosome 12 at 104,218,353 bp
  • C to T, chromosome 12 at 104,781,017 bp
  • C to T, chromosome 13 at 34,344,383 bp
  • A to T, chromosome 14 at 31,265,915 bp
  • C to T, chromosome 14 at 33,941,221 bp
  • A to T, chromosome 14 at 33,958,647 bp
  • T to A, chromosome 15 at 84,331,021 bp
  • T to C, chromosome 15 at 98,598,379 bp
  • C to T, chromosome 16 at 20,655,329 bp
  • A to T, chromosome 16 at 79,024,848 bp
  • C to T, chromosome 19 at 5,704,802 bp
  • G to T, chromosome X at 104,084,949 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0739 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038920-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.