Strain Name:
C57BL/6J-MtgxR0764Btlr/Mmmh
Stock Number:
038944-MU
Citation ID:
RRID:MMRRC_038944-MU
Other Names:
R0764 (G1), C57BL/6J-MtgxR0764Btlr
Major Collection:

Gene Information

Pias3
Name: protein inhibitor of activated STAT 3
Synonyms: Pias3L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229615
Homologene: 4447
Crhr1
Name: corticotropin releasing hormone receptor 1
Synonyms: CRFR1, CRF-R1alpha, CRF 1 receptor, CRF1R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12921
HGNC: HGNC:2357
Homologene: 20920
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Ranbp1
Name: RAN binding protein 1
Synonyms: Htf9a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19385
HGNC: HGNC:9847
Homologene: 21600
Zfp113
Name: zinc finger protein 113
Synonyms: 4732456B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56314
Homologene: 50027
Adipor2
Name: adiponectin receptor 2
Synonyms: 1110001I14Rik, D6Ucla1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 68465
Homologene: 56119
Ap3b1
Name: adaptor-related protein complex 3, beta 1 subunit
Synonyms: rim2, Hps2, recombination induced mutation 2, beta3A, AP-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11774
VEGA: 13
HGNC: HGNC:566
Homologene: 68125
Ago3
Name: argonaute RISC catalytic subunit 3
Synonyms: argonaute 3, eIF2C3, C130014L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 214150
Homologene: 49799
Cbl
Name: Casitas B-lineage lymphoma
Synonyms: Cbl-2, c-Cbl, 4732447J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12402
HGNC: HGNC:1541
Homologene: 3802
Sucla2
Name: succinate-Coenzyme A ligase, ADP-forming, beta subunit
Synonyms: 4930547K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 20916
Homologene: 2856
Tram1
Name: translocating chain-associating membrane protein 1
Synonyms: TRAMP, 1810049E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72265
Homologene: 8621
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, LOC381026, 9330188B09Rik, D630001M17Rik, 4921513O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66725
Homologene: 18982
Fam193a
Name: family with sequence homology 193, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231128
Homologene: 2746
Tnfrsf17
Name: tumor necrosis factor receptor superfamily, member 17
Synonyms: BCM, Tnfrsf13, Tnfrsf13a, BCMA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21935
Homologene: 920
Rnf103
Name: ring finger protein 103
Synonyms: kf-1, Zfp103
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22644
Homologene: 4146
Osbp
Name: oxysterol binding protein
Synonyms: 1110018F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 76303
VEGA: 19
HGNC: HGNC:8503
Homologene: 97668
Nectin2
Name: nectin cell adhesion molecule 2
Synonyms: nectin-2, MPH, Cd112, Pvs, Pvrl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19294
HGNC: HGNC:9707
Homologene: 86092
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269700
Homologene: 28297
Cdkl2
Name: cyclin-dependent kinase-like 2 (CDC2-related kinase)
Synonyms: Kkm, KKIAMRE, 5330436L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 53886
HGNC: HGNC:1782
Homologene: 55793
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Naip-rs3, Birc1e, Lgn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Slc35f4
Name: solute carrier family 35, member F4
Synonyms: 4930550L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 75288
Homologene: 45939
Olfr170
Name: olfactory receptor 170
Synonyms: GA_x54KRFPKG5P-16052703-16051765, MOR273-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258959
Homologene: 128058
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Per2
Name: period circadian clock 2
Synonyms: mPer2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18627
HGNC: HGNC:8846
Homologene: 7885
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Gbp6
Name: guanylate binding protein 6
Synonyms: Mpa2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100702
Homologene: 128731
Angpt4
Name: angiopoietin 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11602
HGNC: HGNC:487
Homologene: 36302
Ttc38
Name: tetratricopeptide repeat domain 38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239570
Homologene: 41208
Kdm1b
Name: lysine (K)-specific demethylase 1B
Synonyms: 4632428N09Rik, Aof1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218214
Homologene: 14695
Cep162
Name: centrosomal protein 162
Synonyms: 4922501C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382090
Homologene: 8930
Abca8a
Name: ATP-binding cassette, sub-family A (ABC1), member 8a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217258
HGNC: HGNC:38
Homologene: 131160
Ly6g2
Name: lymphocyte antigen 6 complex, locus G2
Synonyms: BC025446
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223631
Ina
Name: internexin neuronal intermediate filament protein, alpha
Synonyms: NF-66, NF66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226180
HGNC: HGNC:6057
Homologene: 10433
Fam76a
Name: family with sequence similarity 76, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230789
Homologene: 27071
Olfr1243
Name: olfactory receptor 1243
Synonyms: GA_x6K02T2Q125-50972538-50971621, MOR231-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258971
Homologene: 27317
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: Fmi1, flamingo, Adgrc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
Ano5
Name: anoctamin 5
Synonyms: Gdd1, Tmem16e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233246
Homologene: 100071
Dyrk1b
Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
Synonyms: Mirk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13549
HGNC: HGNC:3092
Homologene: 31253
Ddx49
Name: DEAD box helicase 49
Synonyms: R27090_2, DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234374
Homologene: 41308
Rit2
Name: Ras-like without CAAX 2
Synonyms: Roc2, Rin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 19762
Homologene: 2198
Pcgf1
Name: polycomb group ring finger 1
Synonyms: 2010002K04Rik, Nspc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 69837
Homologene: 13090
Plod3
Name: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
Synonyms: lysyl hydroxylase 3, LH3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26433
HGNC: HGNC:9083
Homologene: 843
Acp4
Name: acid phosphatase 4
Synonyms: EG546967, Acpt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100503991
Homologene: 57200
Slc22a13
Name: solute carrier family 22 (organic cation transporter), member 13
Synonyms: ORCTL3, OCTL3, OCTL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102570
VEGA: 9
HGNC: HGNC:8494
Homologene: 3140
Purb
Name: purine rich element binding protein B
Synonyms: Cager-2, 2310015K15Rik, D11Bwg0414e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19291
HGNC: HGNC:9702
Homologene: 69087
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 13,579,709 bp
  • C to T, chromosome 1 at 91,429,420 bp
  • A to G, chromosome 2 at 52,216,867 bp
  • A to G, chromosome 2 at 89,527,996 bp
  • A to G, chromosome 2 at 151,911,284 bp
  • C to T, chromosome 3 at 96,701,295 bp
  • T to A, chromosome 4 at 126,355,092 bp
  • C to T, chromosome 4 at 132,910,699 bp
  • T to C, chromosome 5 at 34,443,341 bp
  • C to A, chromosome 5 at 92,020,277 bp
  • T to A, chromosome 5 at 105,280,489 bp
  • T to A, chromosome 5 at 121,286,769 bp
  • C to T, chromosome 5 at 136,989,583 bp
  • T to A, chromosome 5 at 138,145,244 bp
  • C to A, chromosome 6 at 71,509,582 bp
  • T to C, chromosome 6 at 83,079,169 bp
  • T to C, chromosome 6 at 119,357,254 bp
  • T to A, chromosome 7 at 19,749,171 bp
  • C to T, chromosome 7 at 28,185,711 bp
  • T to C, chromosome 7 at 44,252,314 bp
  • A to G, chromosome 7 at 46,300,494 bp
  • G to T, chromosome 7 at 51,537,842 bp
  • T to C, chromosome 8 at 70,297,257 bp
  • A to T, chromosome 9 at 44,164,152 bp
  • A to G, chromosome 9 at 87,201,745 bp
  • A to G, chromosome 9 at 108,827,818 bp
  • T to C, chromosome 9 at 119,208,680 bp
  • C to T, chromosome 11 at 6,475,661 bp
  • C to T, chromosome 11 at 104,159,326 bp
  • A to T, chromosome 11 at 110,059,946 bp
  • A to T, chromosome 13 at 47,068,603 bp
  • C to T, chromosome 13 at 94,479,879 bp
  • A to T, chromosome 13 at 100,217,105 bp
  • T to A, chromosome 14 at 49,306,339 bp
  • C to T, chromosome 14 at 73,560,634 bp
  • A to T, chromosome 15 at 8,157,760 bp
  • T to A, chromosome 15 at 75,220,723 bp
  • T to C, chromosome 15 at 85,846,403 bp
  • A to G, chromosome 15 at 91,775,046 bp
  • C to T, chromosome 16 at 11,315,199 bp
  • C to A, chromosome 16 at 18,240,158 bp
  • G to T, chromosome 16 at 19,606,432 bp
  • T to C, chromosome 18 at 31,153,701 bp
  • A to G, chromosome 19 at 11,984,156 bp
  • T to A, chromosome 19 at 47,023,648 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0764 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038944-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.