Strain Name:
C57BL/6J-MtgxR0782Btlr/Mmmh
Stock Number:
038962-MU
Citation ID:
RRID:MMRRC_038962-MU
Other Names:
R0782 (G1), C57BL/6J-MtgxR0782Btlr
Major Collection:

Gene Information

Lactb2
Name: lactamase, beta 2
Synonyms: E430032H21Rik, Cgi-83
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 212442
Homologene: 9349
Smc2
Name: structural maintenance of chromosomes 2
Synonyms: Fin16, CAP-E, Smc2l1, 5730502P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14211
Homologene: 4705
Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Synonyms: Nrf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18024
HGNC: HGNC:7782
Homologene: 2412
Tcof1
Name: treacle ribosome biogenesis factor 1
Synonyms: treacle
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 21453
Homologene: 68049
Zfp292
Name: zinc finger protein 292
Synonyms: 9430062L07Rik, Zn-15, Zfp15, 5730450D02Rik, Krox-10, Zfp-15, Zn-16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30046
Homologene: 8493
Rnf216
Name: ring finger protein 216
Synonyms: Ubce7ip1, 2810055G22Rik, UIP83, F830018F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 108086
Homologene: 19442
Cog7
Name: component of oligomeric golgi complex 7
Synonyms: 5630400E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233824
Homologene: 33431
Csf2rb2
Name: colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
Synonyms: Il3r, Il3rb2, Bil3, BetaIl3, AIC2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12984
VEGA: 15
HGNC: HGNC:2436
Homologene: 339
Arhgap23
Name: Rho GTPase activating protein 23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 58996
Homologene: 104145
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230895
Homologene: 15583
Cspp1
Name: centrosome and spindle pole associated protein 1
Synonyms: 2310020J12Rik, 4930413O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 211660
Homologene: 23487
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Acf1, Wcrf180, Gtl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Ilkap
Name: integrin-linked kinase-associated serine/threonine phosphatase 2C
Synonyms: 1600009O09Rik, PP2C-DELTA, 0710007A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67444
Homologene: 31525
Slc44a3
Name: solute carrier family 44, member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213603
Homologene: 64830
Hmcn1
Name: hemicentin 1
Synonyms: EG545370, LOC240793
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
Zfp831
Name: zinc finger protein 831
Synonyms: OTTMUSG00000017459, ENSMUSG00000050600
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 100043757
Homologene: 19013
Dhx36
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 36
Synonyms: 2810407E23Rik, Ddx36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72162
Homologene: 6356
Unc80
Name: unc-80, NALCN activator
Synonyms: C030018G13Rik, C230061B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329178
Homologene: 122243
Myh8
Name: myosin, heavy polypeptide 8, skeletal muscle, perinatal
Synonyms: Myhsp, MyHC-pn, 4832426G23Rik, Myhs-p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17885
HGNC: HGNC:7578
Homologene: 68256
Efr3b
Name: EFR3 homolog B
Synonyms: C030014M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 668212
VEGA: 12
Homologene: 66195
Ppfia2
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
Synonyms: Liprin-alpha2, E130120L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 327814
VEGA: 10
HGNC: HGNC:9246
Homologene: 27953
Nckap5
Name: NCK-associated protein 5
Synonyms: E030049G20Rik, D130011D22Rik, LOC380609
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210356
Homologene: 35542
Samd3
Name: sterile alpha motif domain containing 3
Synonyms: LOC268288
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 268288
VEGA: 10
Homologene: 67991
Faap100
Name: Fanconi anemia core complex associated protein 100
Synonyms: 2310003H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71885
Homologene: 69394
Serping1
Name: serine (or cysteine) peptidase inhibitor, clade G, member 1
Synonyms: C1nh, C1INH, C1 inhibitor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12258
HGNC: HGNC:1228
Homologene: 44
Cyp2c37
Name: cytochrome P450, family 2. subfamily c, polypeptide 37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 13096
Homologene: 137231
Mylk
Name: myosin, light polypeptide kinase
Synonyms: telokin, MLCK210, Mlck, 9530072E15Rik, nmMlck, A930019C19Rik, MLCK108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 107589
HGNC: HGNC:7590
Homologene: 14202
Impa1
Name: inositol (myo)-1(or 4)-monophosphatase 1
Synonyms: 2900059K10Rik, 2610002K09Rik, lithium-sensitive myo-inositol monophosphatase A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 55980
HGNC: HGNC:6050
Homologene: 4043
B3glct
Name: beta-3-glucosyltransferase
Synonyms: LOC381694, B3galtl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381694
Homologene: 14978
Slc39a10
Name: solute carrier family 39 (zinc transporter), member 10
Synonyms: 2900042E17Rik, Zip10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227059
Homologene: 34076
Cdc14a
Name: CDC14 cell division cycle 14A
Synonyms: Cdc14, CDC14a1, CDC14A2, A830059A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229776
HGNC: HGNC:1718
Homologene: 75343
Dcst1
Name: DC-STAMP domain containing 1
Synonyms: A330106H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77772
Homologene: 14981
Rasa4
Name: RAS p21 protein activator 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54153
Homologene: 5080
Vamp5
Name: vesicle-associated membrane protein 5
Synonyms: Camp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 53620
Homologene: 4833
Kbtbd8
Name: kelch repeat and BTB (POZ) domain containing 8
Synonyms: SSEC 51, SSEC51, SSEC-51, Takrp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243574
Homologene: 13043
Napa
Name: N-ethylmaleimide sensitive fusion protein attachment protein alpha
Synonyms: RA81, SNARE, SNAPA, a-SNAP, hyh, 1500039N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 108124
HGNC: HGNC:7641
Homologene: 2839
Olfr609
Name: olfactory receptor 609
Synonyms: MOR9-1, GA_x6K02T2PBJ9-6207735-6206776
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259086
Homologene: 64952
Smpd1
Name: sphingomyelin phosphodiesterase 1, acid lysosomal
Synonyms: ASM, acid sphingomyelinase, aSMase, A-SMase, Zn-SMase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20597
Homologene: 457
Gm20498
Name: predicted gene 20498
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 105940408
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 10,129,974 bp
  • T to G, chromosome 1 at 13,647,451 bp
  • T to C, chromosome 1 at 46,835,996 bp
  • A to G, chromosome 1 at 66,622,581 bp
  • C to T, chromosome 1 at 91,378,550 bp
  • G to A, chromosome 1 at 125,981,541 bp
  • A to G, chromosome 1 at 150,753,665 bp
  • T to C, chromosome 2 at 75,676,833 bp
  • G to A, chromosome 2 at 84,767,446 bp
  • A to G, chromosome 2 at 174,646,630 bp
  • A to T, chromosome 3 at 10,322,896 bp
  • A to T, chromosome 3 at 62,506,714 bp
  • A to G, chromosome 3 at 89,357,500 bp
  • A to G, chromosome 3 at 116,322,136 bp
  • T to G, chromosome 3 at 121,532,151 bp
  • T to C, chromosome 4 at 34,839,382 bp
  • C to A, chromosome 4 at 52,469,799 bp
  • G to A, chromosome 4 at 145,126,625 bp
  • A to G, chromosome 5 at 136,104,532 bp
  • T to C, chromosome 5 at 143,068,892 bp
  • C to T, chromosome 5 at 149,726,810 bp
  • T to C, chromosome 6 at 72,369,470 bp
  • C to T, chromosome 6 at 95,122,232 bp
  • T to C, chromosome 7 at 16,115,267 bp
  • C to A, chromosome 7 at 103,492,515 bp
  • T to A, chromosome 7 at 105,555,343 bp
  • C to A, chromosome 7 at 121,943,797 bp
  • A to G, chromosome 10 at 26,270,240 bp
  • C to T, chromosome 10 at 106,927,731 bp
  • T to A, chromosome 11 at 67,289,754 bp
  • C to T, chromosome 11 at 97,500,554 bp
  • A to G, chromosome 11 at 120,376,704 bp
  • G to A, chromosome 12 at 3,984,686 bp
  • A to T, chromosome 12 at 54,894,488 bp
  • A to T, chromosome 12 at 81,532,733 bp
  • C to A, chromosome 15 at 78,286,751 bp
  • G to C, chromosome 16 at 34,879,475 bp
  • G to A, chromosome 18 at 60,816,280 bp
  • A to G, chromosome 19 at 39,993,825 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0782 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038962-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.