Strain Name:
C57BL/6J-MtgxR0792Btlr/Mmmh
Stock Number:
038972-MU
Citation ID:
RRID:MMRRC_038972-MU
Other Names:
R0792 (G1), C57BL/6J-MtgxR0792Btlr
Major Collection:

Gene Information

Bdnf
Name: brain derived neurotrophic factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12064
HGNC: HGNC:1033
Homologene: 7245
Gli1
Name: GLI-Kruppel family member GLI1
Synonyms: Zfp-5, Zfp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14632
VEGA: 10
HGNC: HGNC:4317
Homologene: 3859
Glt8d1
Name: glycosyltransferase 8 domain containing 1
Synonyms: 5430414N14Rik, 2410004H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 76485
VEGA: 14
Homologene: 32720
Dlc1
Name: deleted in liver cancer 1
Synonyms: p122-RhoGAP, STARD12, Arhgap7, A730069N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 50768
HGNC: HGNC:2897
Homologene: 4442
Dock1
Name: dedicator of cytokinesis 1
Synonyms: D630004B07Rik, 9130006G06Rik, Dock180, b2b3190Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330662
HGNC: HGNC:2987
Homologene: 55575
Ltbp4
Name: latent transforming growth factor beta binding protein 4
Synonyms: 2310046A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 108075
HGNC: HGNC:6717
Homologene: 2645
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: FKBP-rapamycin-associated protein FRAP, 2610315D21Rik, RAPT1, RAFT1, flat, Frap1, mechanistic target of rapamycin (serine/threonine kinase)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Paip1
Name: polyadenylate binding protein-interacting protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218693
Homologene: 4709
Armh3
Name: armadillo-like helical domain containing 3
Synonyms: 9130011E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 71617
VEGA: 19
Homologene: 15843
Cpne1
Name: copine I
Synonyms: 1810028N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 266692
HGNC: HGNC:2314
Homologene: 36501
Slc30a6
Name: solute carrier family 30 (zinc transporter), member 6
Synonyms: ZnT6, ZnT-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 210148
VEGA: 17
Homologene: 32380
Cep68
Name: centrosomal protein 68
Synonyms: 6030463E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216543
Homologene: 65235
Ap3d1
Name: adaptor-related protein complex 3, delta 1 subunit
Synonyms: mBLVR1, Bolvr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11776
VEGA: 10
HGNC: HGNC:568
Homologene: 2926
Nt5c3
Name: 5'-nucleotidase, cytosolic III
Synonyms: p36, lupin, Umph-1, PN-1, cN-III, PSN1, PN-I, Umph1, 2610206B05Rik, 1600024P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 107569
Homologene: 9534
Scube1
Name: signal peptide, CUB domain, EGF-like 1
Synonyms: A630023E24Rik, 7330410C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 64706
Homologene: 11224
Grin2c
Name: glutamate receptor, ionotropic, NMDA2C (epsilon 3)
Synonyms: NMDAR2C, NR2C, GluRepsilon3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14813
HGNC: HGNC:4587
Homologene: 647
Lamc1
Name: laminin, gamma 1
Synonyms: Lamb2, laminin B2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226519
HGNC: HGNC:6492
Homologene: 1724
Rpl7
Name: ribosomal protein L7
Synonyms: Rpl7a, Surf-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19989
Homologene: 87772
Serpina3c
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3C
Synonyms: Kalbp, 1A1, Klkbp, alpha-1 antiproteinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16625
HGNC: HGNC:16
Homologene: 111129
Acsl5
Name: acyl-CoA synthetase long-chain family member 5
Synonyms: 1700030F05Rik, Facl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 433256
VEGA: 19
Homologene: 69208
Cntrl
Name: centriolin
Synonyms: IB3/5, 6720467O09Rik, Ma2a8, Cep1, b2b1468Clo, Cep110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26920
HGNC: HGNC:1858
Homologene: 38260
Ncstn
Name: nicastrin
Synonyms: nicastrin, 9430068N19Rik, Nct, D1Dau13e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 59287
Homologene: 41029
Raver2
Name: ribonucleoprotein, PTB-binding 2
Synonyms: A430091O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242570
Homologene: 18829
Atp2b2
Name: ATPase, Ca++ transporting, plasma membrane 2
Synonyms: PMCA2, D6Abb2e, wms, jog, Tmy, Gena300
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11941
HGNC: HGNC:815
Homologene: 56150
Prdm14
Name: PR domain containing 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 383491
Homologene: 11556
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: CD91, A2mr, b2b1554Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: Scy, Crsh, crash, Adgrc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
Trak2
Name: trafficking protein, kinesin binding 2
Synonyms: GRIF-1, CALS-C, OIP98, GRIF1, 4733401O11Rik, Als2cr3, 2900022D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70827
Homologene: 22861
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Naip6
Name: NLR family, apoptosis inhibitory protein 6
Synonyms: Naip-rs4A, Naip-rs4, Birc1f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17952
HGNC: HGNC:7634
Homologene: 113589
Ccdc180
Name: coiled-coil domain containing 180
Synonyms: LOC381522, E230008N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381522
Homologene: 117988
Akr1c13
Name: aldo-keto reductase family 1, member C13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 27384
Homologene: 121208
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: DY6, 2310047C17Rik, 1110004P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Sobp
Name: sine oculis binding protein
Synonyms: 2900009C16Rik, 5330439J01Rik, Jxc1, jc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 109205
Homologene: 41216
Evpl
Name: envoplakin
Synonyms: 210kDa protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14027
HGNC: HGNC:3503
Homologene: 1506
C330019G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Prss1
Name: protease, serine 1 (trypsin 1)
Synonyms: PRSS1, Try-1, Try1, Trygn16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 114228
HGNC: HGNC:9486
Homologene: 88408
Or5p81
Name: olfactory receptor family 5 subfamily P member 81
Synonyms: GA_x6K02T2PBJ9-10997715-10998659, MOR204-34, Olfr510
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258308
Myom1
Name: myomesin 1
Synonyms: skelemin, D430047A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17929
VEGA: 17
HGNC: HGNC:7613
Homologene: 31196
Twnk
Name: twinkle mtDNA helicase
Synonyms: twinkle, Twinl, D19Ertd626e, Peo1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226153
VEGA: 19
HGNC: HGNC:1160
Homologene: 11052
Vmn1r173
Name: vomeronasal 1 receptor 173
Synonyms: Gm5892
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 545934
Homologene: 79577
Zfp820
Name: zinc finger protein 820
Synonyms: 2610036F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 75424
VEGA: 17
Adgrb1
Name: adhesion G protein-coupled receptor B1
Synonyms: B830018M07Rik, Bai1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 107831
HGNC: HGNC:943
Homologene: 1287
Krt2
Name: keratin 2
Synonyms: Krt2-2, Krt2e, Krt2-17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16681
HGNC: HGNC:6439
Zfp267
Name: zinc finger protein 267
Synonyms: D3Ertd254e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 241944
Homologene: 117700
C9
Name: complement component 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12279
HGNC: HGNC:1358
Homologene: 74406
Sorcs3
Name: sortilin-related VPS10 domain containing receptor 3
Synonyms: 6330404A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66673
VEGA: 19
Homologene: 8986
H2-Ob
Name: histocompatibility 2, O region beta locus
Synonyms: Ob, H-2I, H2-IAb2, H2-Ab, H-2Ob, H2-Ab2, A-beta2, A-beta-2, vic1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15002
HGNC: HGNC:4937
Homologene: 1602
Bpifa5
Name: BPI fold containing family A, member 5
Synonyms: 2310074B19Rik, 2310021H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67135
Homologene: 12087
Slc16a13
Name: solute carrier family 16 (monocarboxylic acid transporters), member 13
Synonyms: 1700007D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69309
Homologene: 71749
Jpt2
Name: Jupiter microtubule associated homolog 2
Synonyms: 2810430B18Rik, D17Ertd441e, Hn1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 52009
VEGA: 17
Homologene: 16934
Fmo6
Name: flavin containing monooxygenase 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226565
Homologene: 68130
Ubox5
Name: U box domain containing 5
Synonyms: UIP5, 1500010O06Rik, C330018L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140629
Homologene: 8972
Rps3a2
Name: ribosomal protein S3A2
Synonyms: Gm10119
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100043780
Or5ac21
Name: olfactory receptor family 5 subfamily AC member 21
Synonyms: GA_x54KRFPKG5P-55517445-55518365, MOR182-5, Olfr203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258479
Homologene: 122781
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 13,125,744 bp
  • A to T, chromosome 1 at 16,102,679 bp
  • A to T, chromosome 1 at 58,903,661 bp
  • C to A, chromosome 1 at 153,234,580 bp
  • T to G, chromosome 1 at 153,234,595 bp
  • T to C, chromosome 1 at 153,234,612 bp
  • C to T, chromosome 1 at 162,920,563 bp
  • A to G, chromosome 1 at 172,071,505 bp
  • T to A, chromosome 2 at 35,155,279 bp
  • G to A, chromosome 2 at 109,724,118 bp
  • A to T, chromosome 2 at 130,600,710 bp
  • G to T, chromosome 2 at 154,165,619 bp
  • G to T, chromosome 2 at 156,077,419 bp
  • A to G, chromosome 3 at 36,164,562 bp
  • T to C, chromosome 4 at 45,927,975 bp
  • T to A, chromosome 4 at 101,102,950 bp
  • T to C, chromosome 4 at 148,462,910 bp
  • A to G, chromosome 5 at 32,828,423 bp
  • T to C, chromosome 6 at 41,458,944 bp
  • T to C, chromosome 6 at 56,886,749 bp
  • C to T, chromosome 6 at 113,773,388 bp
  • A to G, chromosome 7 at 23,702,735 bp
  • G to T, chromosome 7 at 27,325,060 bp
  • A to G, chromosome 7 at 108,668,157 bp
  • A to G, chromosome 7 at 134,874,150 bp
  • G to A, chromosome 7 at 141,639,559 bp
  • A to T, chromosome 8 at 36,938,548 bp
  • G to A, chromosome 10 at 39,105,132 bp
  • A to C, chromosome 10 at 43,022,693 bp
  • A to T, chromosome 10 at 80,708,479 bp
  • A to T, chromosome 10 at 127,332,577 bp
  • G to T, chromosome 10 at 127,567,364 bp
  • A to T, chromosome 10 at 127,575,286 bp
  • A to T, chromosome 11 at 20,240,652 bp
  • T to C, chromosome 11 at 65,896,001 bp
  • A to T, chromosome 11 at 70,220,631 bp
  • G to A, chromosome 11 at 115,250,646 bp
  • T to A, chromosome 11 at 116,227,723 bp
  • T to A, chromosome 12 at 104,151,546 bp
  • T to C, chromosome 13 at 4,194,112 bp
  • A to G, chromosome 13 at 100,283,766 bp
  • T to C, chromosome 13 at 119,430,318 bp
  • T to C, chromosome 14 at 31,011,241 bp
  • T to C, chromosome 14 at 88,123,168 bp
  • T to A, chromosome 15 at 6,486,762 bp
  • A to G, chromosome 15 at 74,580,617 bp
  • T to A, chromosome 15 at 83,628,076 bp
  • A to G, chromosome 15 at 85,931,276 bp
  • A to G, chromosome 15 at 101,816,497 bp
  • A to T, chromosome 16 at 59,303,989 bp
  • T to C, chromosome 17 at 21,819,528 bp
  • C to A, chromosome 17 at 24,948,673 bp
  • C to T, chromosome 17 at 34,242,614 bp
  • A to T, chromosome 17 at 71,121,136 bp
  • T to C, chromosome 17 at 74,415,645 bp
  • G to T, chromosome 19 at 9,016,734 bp
  • T to C, chromosome 19 at 45,010,254 bp
  • A to T, chromosome 19 at 45,933,868 bp
  • C to A, chromosome 19 at 48,706,009 bp
  • T to C, chromosome 19 at 55,280,492 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0792 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038972-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.