Strain Name:
C57BL/6J-MtgxR0800Btlr/Mmmh
Stock Number:
038980-MU
Citation ID:
RRID:MMRRC_038980-MU
Other Names:
R0800 (G1), C57BL/6J-MtgxR0800Btlr
Major Collection:

Gene Information

Itga8
Name: integrin alpha 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241226
HGNC: HGNC:6144
Homologene: 37396
Cacna1g
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms: Cav3.1d, a1G
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12291
HGNC: HGNC:1394
Homologene: 22544
Gnaq
Name: guanine nucleotide binding protein, alpha q polypeptide
Synonyms: 1110005L02Rik, Dsk1, Dsk10, GqI, 6230401I02Rik, G alpha q, Galphaq, Gq
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 14682
HGNC: HGNC:4390
Homologene: 1566
Trappc9
Name: trafficking protein particle complex 9
Synonyms: 1810044A24Rik, 2900005P22Rik, Nibp, TRS130, 4632408O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 76510
VEGA: 15
Homologene: 81931
Usp19
Name: ubiquitin specific peptidase 19
Synonyms: 8430421I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71472
Homologene: 41730
Stat3
Name: signal transducer and activator of transcription 3
Synonyms: 1110034C02Rik, Aprf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20848
Homologene: 7960
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: VPARP, Adprtl1, VAULT3, PH5P, p193, E230037B21Rik, C030027K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Gabpb1
Name: GA repeat binding protein, beta 1
Synonyms: E4TF1-53, BABPB2, E4TF1, GABPB1-1, GABPB1-2, E4Tf1B, E4TF1-47, NRF2B1, NRF2B2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14391
HGNC: HGNC:4074
Homologene: 7723
Polr3c
Name: polymerase (RNA) III (DNA directed) polypeptide C
Synonyms: RPC3, RPC62, 4933407E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74414
Homologene: 38185
Cic
Name: capicua transcriptional repressor
Synonyms: 1200010B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 71722
Homologene: 87637
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: LOC381341, Dnahc7, Dnahc7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 627872
Homologene: 41287
Dzip3
Name: DAZ interacting protein 3, zinc finger
Synonyms: 6430549P11Rik, 2A-HUB, 2310047C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224170
Homologene: 8771
Gprc5c
Name: G protein-coupled receptor, family C, group 5, member C
Synonyms: 3200002M13Rik, 1110028I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 70355
Homologene: 11099
Il17f
Name: interleukin 17F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 257630
Homologene: 17115
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, Dnahc8, P1-Loop
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Kifc5b
Name: kinesin family member C5B
Synonyms: kinesin family c-terminal 5B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 16580
VEGA: 17
HGNC: HGNC:6389
Homologene: 83229
Hibadh
Name: 3-hydroxyisobutyrate dehydrogenase
Synonyms: 6430402H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 58875
HGNC: HGNC:4907
Homologene: 15088
Myh6
Name: myosin, heavy polypeptide 6, cardiac muscle, alpha
Synonyms: alpha cardiac MHC, alpha-MHC, A830009F23Rik, cardiomyopathy, hypertrophic 1, Myhca, alphaMHC, Myhc-a, alpha myosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 17888
HGNC: HGNC:7576
Homologene: 124414
Sox6
Name: SRY (sex determining region Y)-box 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20679
Homologene: 22631
Sell
Name: selectin, lymphocyte
Synonyms: Ly-m22, Ly-22, Lyam1, Lyam-1, LECAM-1, CD62L, L-selectin, Lnhr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20343
Homologene: 539
Zfp750
Name: zinc finger protein 750
Synonyms: A030007D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 319530
Homologene: 36423
Dok7
Name: docking protein 7
Synonyms: Dok-7, Oit5, EF-12, A930013K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231134
Homologene: 18210
Nlgn2
Name: neuroligin 2
Synonyms: NL2, NLG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216856
Homologene: 69317
Tapbp
Name: TAP binding protein
Synonyms: TPN, tapasin, D17Wsu91e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21356
Homologene: 2401
Zhx2
Name: zinc fingers and homeoboxes 2
Synonyms: Raf, Afr-1, Afr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 387609
Homologene: 8968
Fer1l4
Name: fer-1-like 4 (C. elegans)
Synonyms: 9130402C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74562
Homologene: 19075
Mmp12
Name: matrix metallopeptidase 12
Synonyms: Mmel, macrophage elastase, MMP12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17381
HGNC: HGNC:7158
Homologene: 20547
Olfr1406
Name: olfactory receptor 1406
Synonyms: MOR267-5, GA_x6K02T2R7CC-664297-665229
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258758
Homologene: 133644
Fmo2
Name: flavin containing monooxygenase 2
Synonyms: 2310008D08Rik, 2310042I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 55990
HGNC: HGNC:3770
Homologene: 86882
Kprp
Name: keratinocyte expressed, proline-rich
Synonyms: 1110001M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 433619
Homologene: 54921
Chd5
Name: chromodomain helicase DNA binding protein 5
Synonyms: 4930532L22Rik, B230399N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269610
Homologene: 56712
Klra2
Name: killer cell lectin-like receptor, subfamily A, member 2
Synonyms: Ly49b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16633
Homologene: 133782
Txlnb
Name: taxilin beta
Synonyms: 2310001N14Rik, Mdp77
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 378431
Homologene: 44534
Speg
Name: SPEG complex locus
Synonyms: SPEGalpha, SPEGbeta, BPEG, SPEG, D1Bwg1450e, Apeg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11790
Homologene: 55619
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: C230094A16Rik, 2900083P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237711
Homologene: 104282
Palm2
Name: paralemmin 2
Synonyms: 53-H12, pEN70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
Tgm6
Name: transglutaminase 6
Synonyms: TGM3L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241636
Homologene: 27970
Gzmd
Name: granzyme D
Synonyms: Ctla-5, Ctla5, CCP5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 14941
HGNC: HGNC:4710
Homologene: 133275
Ces3b
Name: carboxylesterase 3B
Synonyms: Gm4738, ES31L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13909
HGNC: HGNC:1865
Homologene: 84407
Piwil2
Name: piwi-like RNA-mediated gene silencing 2
Synonyms: Miwi like, mili
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 57746
VEGA: 14
Homologene: 23071
Vmn2r17
Name: vomeronasal 2, receptor 17
Synonyms: EG384221
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 384221
Homologene: 104825
Iqca
Name: IQ motif containing with AAA domain
Synonyms: 4930585L22Rik, 4930465P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74918
Homologene: 49784
Papss1
Name: 3'-phosphoadenosine 5'-phosphosulfate synthase 1
Synonyms: Asapk, SK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 23971
HGNC: HGNC:8603
Homologene: 81740
Hbq1b
Name: hemoglobin, theta 1B
Synonyms: F830116E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 544763
HGNC: HGNC:4833
Homologene: 3895
Pou3f3
Name: POU domain, class 3, transcription factor 3
Synonyms: Brn1, HST011, Otf8, Brn-1, urehr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18993
HGNC: HGNC:9216
Homologene: 68509
Olfr1232
Name: olfactory receptor 1232
Synonyms: MOR233-18, GA_x6K02T2Q125-50770831-50769896
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258320
Homologene: 74068
Cst13
Name: cystatin 13
Synonyms: 1700006C19Rik, Cymg1, cystatin T
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 69294
Homologene: 41707
Stra6l
Name: STRA6-like
Synonyms: 1300002K09Rik, Rbpr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74152
Homologene: 81924
Pskh1
Name: protein serine kinase H1
Synonyms: E130013P03Rik, b2b1230Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244631
HGNC: HGNC:9529
Homologene: 48461
Pla2g12b
Name: phospholipase A2, group XIIB
Synonyms: hlb218, 2010002E04Rik, Pla2g13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 69836
Homologene: 11356
B230217C12Rik
Name: RIKEN cDNA B230217C12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 68127
Rom1
Name: rod outer segment membrane protein 1
Synonyms: Tspan23, Rgsc1156, M101156, Rom-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 19881
VEGA: 19
Homologene: 276
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 20,777,953 bp
  • A to G, chromosome 1 at 42,698,367 bp
  • A to G, chromosome 1 at 53,565,696 bp
  • T to C, chromosome 1 at 75,423,489 bp
  • C to A, chromosome 1 at 90,142,731 bp
  • C to T, chromosome 1 at 162,876,814 bp
  • T to A, chromosome 1 at 164,066,201 bp
  • C to T, chromosome 1 at 173,184,060 bp
  • A to T, chromosome 2 at 12,193,551 bp
  • A to G, chromosome 2 at 89,325,664 bp
  • A to T, chromosome 2 at 126,630,328 bp
  • G to A, chromosome 2 at 130,143,422 bp
  • A to T, chromosome 2 at 148,830,327 bp
  • A to G, chromosome 2 at 156,045,663 bp
  • T to C, chromosome 3 at 92,825,035 bp
  • C to A, chromosome 3 at 96,719,311 bp
  • T to A, chromosome 3 at 131,599,854 bp
  • A to G, chromosome 4 at 45,882,797 bp
  • T to A, chromosome 4 at 57,709,650 bp
  • A to G, chromosome 4 at 152,356,157 bp
  • T to C, chromosome 5 at 35,075,289 bp
  • T to A, chromosome 5 at 109,427,326 bp
  • T to A, chromosome 6 at 52,556,505 bp
  • A to T, chromosome 6 at 131,230,174 bp
  • A to G, chromosome 7 at 25,285,237 bp
  • A to G, chromosome 7 at 115,579,014 bp
  • T to A, chromosome 8 at 105,085,269 bp
  • A to G, chromosome 8 at 105,913,606 bp
  • A to T, chromosome 9 at 7,357,827 bp
  • A to G, chromosome 9 at 108,495,154 bp
  • A to G, chromosome 10 at 17,799,492 bp
  • A to G, chromosome 10 at 59,403,820 bp
  • A to G, chromosome 11 at 29,749,877 bp
  • A to C, chromosome 11 at 32,287,581 bp
  • A to G, chromosome 11 at 69,825,997 bp
  • T to C, chromosome 11 at 94,426,439 bp
  • T to C, chromosome 11 at 97,841,260 bp
  • A to G, chromosome 11 at 100,894,155 bp
  • A to C, chromosome 11 at 114,866,711 bp
  • T to C, chromosome 11 at 121,512,012 bp
  • A to G, chromosome 14 at 54,953,278 bp
  • A to G, chromosome 14 at 56,132,491 bp
  • A to G, chromosome 14 at 56,589,951 bp
  • A to T, chromosome 14 at 70,409,037 bp
  • A to C, chromosome 15 at 57,822,728 bp
  • A to T, chromosome 15 at 72,953,132 bp
  • A to G, chromosome 16 at 48,953,808 bp
  • T to A, chromosome 17 at 26,923,184 bp
  • T to A, chromosome 17 at 30,704,662 bp
  • A to G, chromosome 17 at 33,926,253 bp
  • T to A, chromosome 19 at 8,928,908 bp
  • T to A, chromosome 19 at 16,335,064 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0800 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038980-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.