Strain Name:
C57BL/6J-MtgxR0826Btlr/Mmmh
Stock Number:
039006-MU
Citation ID:
RRID:MMRRC_039006-MU
Other Names:
R0826 (G1), C57BL/6J-MtgxR0826Btlr
Major Collection:

Strain Information

Lamb3
Name: laminin, beta 3
Synonyms: nicein, 125kDa
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16780
HGNC: HGNC:6490
Homologene: 191
Snx2
Name: sorting nexin 2
Synonyms: 0610030A03Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67804
VEGA: 18
Homologene: 2332
Atp1a1
Name: ATPase, Na+/K+ transporting, alpha 1 polypeptide
Synonyms: Atpa-1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11928
HGNC: HGNC:799
Homologene: 564
Clasrp
Name: CLK4-associating serine/arginine rich protein
Synonyms: SWAP2, Sfrs16, Srsf16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 53609
Homologene: 134306
Epb41l2
Name: erythrocyte membrane protein band 4.1 like 2
Synonyms: 4.1G, D10Ertd398e, Epb4.1l2, NBL2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13822
VEGA: 10
HGNC: HGNC:3379
Homologene: 37478
Ctnnbl1
Name: catenin, beta like 1
Synonyms: FLJ21108, NYD-SP19, P14L, 5730471K09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66642
Homologene: 12003
Yeats2
Name: YEATS domain containing 2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208146
VEGA: 16
Homologene: 9967
Exoc2
Name: exocyst complex component 2
Synonyms: 2410030I24Rik, Sec5, Sec5l1, Gm29675
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66482
Homologene: 10122
Ppp1r12a
Name: protein phosphatase 1, regulatory subunit 12A
Synonyms: Mypt1, 5730577I22Rik, D10Ertd625e, 1200015F06Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17931
VEGA: 10
HGNC: HGNC:7618
Homologene: 1855
Arhgef17
Name: Rho guanine nucleotide exchange factor 17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 207212
Homologene: 129601
Enpp3
Name: ectonucleotide pyrophosphatase/phosphodiesterase 3
Synonyms: CD203c
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 209558
VEGA: 10
HGNC: HGNC:3358
Homologene: 3683
Zfp457
Name: zinc finger protein 457
Synonyms: Rslcan-6
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 431706
Homologene: 75311
Mmp27
Name: matrix metallopeptidase 27
Synonyms: LOC234911
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 234911
Homologene: 23345
Dpf2
Name: double PHD fingers 2
Synonyms: ubi-d4, Req, 2210010M07Rik, requiem, Baf45d
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19708
HGNC: HGNC:9964
Homologene: 21265
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Wcrf180, Acf1, Gtl5
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Lsm14a
Name: LSM14A mRNA processing body assembly factor
Synonyms: Tral, 2700023B17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67070
Homologene: 40537
Sbk1
Name: SH3-binding kinase 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 104175
Homologene: 17084
Tmem131l
Name: transmembrane 131 like
Synonyms: D930015E06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229473
Homologene: 9057
Rtn3
Name: reticulon 3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20168
VEGA: 19
Homologene: 24934
Baiap3
Name: BAI1-associated protein 3
Synonyms: LOC381076
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 545192
HGNC: HGNC:948
Homologene: 20844
Dnah1
Name: dynein, axonemal, heavy chain 1
Synonyms: E030034C22Rik, Dnahc1, G1-415-19, MDHC7, ferf1, B230373P09Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110084
VEGA: 14
HGNC: HGNC:2940
Homologene: 67131
Tsc2
Name: TSC complex subunit 2
Synonyms: tuberous sclerosis 2, tuberin, Nafld
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22084
VEGA: 17
Homologene: 462
4931406C07Rik
Name: RIKEN cDNA 4931406C07 gene
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70984
VEGA: 9
Homologene: 8531
Myo16
Name: myosin XVI
Synonyms: BM140241, Nyap3, C230040D10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244281
Homologene: 34710
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 229003
Homologene: 14118
Col19a1
Name: collagen, type XIX, alpha 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12823
HGNC: HGNC:2196
Homologene: 55608
Adamts16
Name: ADAM metallopeptidase with thrombospondin type 1 motif 16
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 271127
Homologene: 15146
Or13c3
Name: olfactory receptor family 13 subfamily C member 3
Synonyms: GA_x6K02T2N78B-7137430-7138383, Olfr273, MOR262-8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258821
Homologene: 73999
Catsperg2
Name: cation channel sperm associated auxiliary subunit gamma 2
Synonyms: 1700067C01Rik, CATSPERG
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76718
Homologene: 10915
Kif21a
Name: kinesin family member 21A
Synonyms: N-5 kinesin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16564
VEGA: 15
Homologene: 56761
Ror2
Name: receptor tyrosine kinase-like orphan receptor 2
Synonyms: Ntrkr2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 26564
Homologene: 55831
Gtf2ird2
Name: GTF2I repeat domain containing 2
Synonyms: 1700012P16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 114674
Homologene: 24941
Myoz1
Name: myozenin 1
Synonyms: calsarcin-2, FATZ, 2310001N11Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 59011
VEGA: 14
Homologene: 23311
Slco6c1
Name: solute carrier organic anion transporter family, member 6c1
Synonyms: 4933404A18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74441
Homologene: 65259
Arfgef3
Name: ARFGEF family member 3
Synonyms: B930094H20Rik, D10Bwg1379e, BIG3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215821
VEGA: 10
Homologene: 41366
Ica1
Name: islet cell autoantigen 1
Synonyms: ICA69, 69kDa
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 15893
HGNC: HGNC:5343
Homologene: 7777
Or4a77
Name: olfactory receptor family 4 subfamily A member 77
Synonyms: MOR231-7, Olfr1250, GA_x6K02T2Q125-51098877-51097933
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258967
Homologene: 128094
Mest
Name: mesoderm specific transcript
Synonyms: Peg1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17294
HGNC: HGNC:7028
Homologene: 1800
Col11a1
Name: collagen, type XI, alpha 1
Synonyms: C530001D20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12814
HGNC: HGNC:2186
Homologene: 56389
Pik3cg
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Synonyms: PI3Kgamma, PI3Kgamma, p110gamma, 5830428L06Rik, PI(3)Kgamma
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 30955
HGNC: HGNC:8978
Homologene: 68269
Tnfrsf8
Name: tumor necrosis factor receptor superfamily, member 8
Synonyms: CD30
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21941
Homologene: 949
Shpk
Name: sedoheptulokinase
Synonyms: 4930431K22Rik, Carkl
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74637
HGNC: HGNC:1492
Homologene: 8319
Olfr144
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Dsc3
Name: desmocollin 3
Synonyms: 5430426I24Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13507
VEGA: 18
HGNC: HGNC:3037
Homologene: 1462
Rab32
Name: RAB32, member RAS oncogene family
Synonyms: 2810011A17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67844
HGNC: HGNC:9772
Homologene: 38233
Cttnbp2
Name: cortactin binding protein 2
Synonyms: ORF4, 4732477G22Rik, 3010022N24Rik, Cortbp2, 9130022E09Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 30785
Homologene: 14125
Zfp11
Name: zinc finger protein 11
Synonyms: Zfp-11, Krox-6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22648
Homologene: 87241
Trim30c
Name: tripartite motif-containing 30C
Synonyms: Gm5598, Trim30-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 434219
Arhgef40
Name: Rho guanine nucleotide exchange factor 40
Synonyms: E130112L23Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268739
Homologene: 19560
Osbpl3
Name: oxysterol binding protein-like 3
Synonyms: OSBP3, 6720421I08Rik, ORP3, 1200014M06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71720
Homologene: 49422
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Upf3a
Name: UPF3 regulator of nonsense transcripts homolog A (yeast)
Synonyms: 4930546M19Rik, UPF3, RENT3A, 2600001C03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67031
Homologene: 23395
Nlrp5
Name: NLR family, pyrin domain containing 5
Synonyms: Op1, Mater, Nalp5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23968
Homologene: 65105
Ift56
Name: intraflagellar transport 56
Synonyms: hydrocephalic-polydactyl, hop, hpy, Ttc26, 9430097H08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 264134
Homologene: 11786
Atg10
Name: autophagy related 10
Synonyms: 5430428K15Rik, Apg10p, APG10, 5330424L23Rik, Apg10l
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66795
VEGA: 13
Homologene: 12036
Iqca1
Name: IQ motif containing with AAA domain 1
Synonyms: Iqca, 4930585L22Rik, 4930465P12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74918
Homologene: 49784
Tle2
Name: transducin-like enhancer of split 2
Synonyms: Grg2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 21886
Homologene: 20693
Fam243
Name: family with sequence similarity 243
Synonyms: 4930563D23Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 75328
VEGA: 16
Homologene: 57100
4930433I11Rik
Name: RIKEN cDNA 4930433I11 gene
Synonyms: LOC243944
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243944
Homologene: 77912
Lrfn3
Name: leucine rich repeat and fibronectin type III domain containing 3
Synonyms: A530045B06Rik, SALM4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233067
Homologene: 11558
Tpmt
Name: thiopurine methyltransferase
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 22017
Homologene: 313
Anxa10
Name: annexin A10
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 26359
HGNC: HGNC:534
Homologene: 21409
Fpr-rs7
Name: formyl peptide receptor, related sequence 7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 321021
HGNC: HGNC:3827
Optc
Name: opticin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269120
HGNC: HGNC:8158
Homologene: 8652
Pdzd9
Name: PDZ domain containing 9
Synonyms: 4930408O21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67983
Homologene: 27865
Or2y1c
Name: olfactory receptor family 2 subfamily Y member 1C
Synonyms: Olfr1386, GA_x6K02T2QP88-5964781-5963852, MOR256-50
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 257888
Homologene: 86692
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 24,526,386 bp
  • C to A, chromosome 1 at 90,142,731 bp
  • C to T, chromosome 1 at 97,128,101 bp
  • T to C, chromosome 1 at 133,905,155 bp
  • A to G, chromosome 1 at 153,152,082 bp
  • T to A, chromosome 1 at 193,330,908 bp
  • A to C, chromosome 2 at 89,656,837 bp
  • C to T, chromosome 2 at 157,799,417 bp
  • C to T, chromosome 2 at 181,240,853 bp
  • T to C, chromosome 3 at 83,898,417 bp
  • A to G, chromosome 3 at 101,584,853 bp
  • G to A, chromosome 3 at 114,138,765 bp
  • C to T, chromosome 4 at 52,855,566 bp
  • A to G, chromosome 4 at 145,285,138 bp
  • A to G, chromosome 5 at 129,657,525 bp
  • T to C, chromosome 5 at 134,216,955 bp
  • A to G, chromosome 6 at 8,667,375 bp
  • A to G, chromosome 6 at 18,405,178 bp
  • C to A, chromosome 6 at 30,742,814 bp
  • A to G, chromosome 6 at 38,425,114 bp
  • A to T, chromosome 6 at 50,346,377 bp
  • G to T, chromosome 7 at 19,584,301 bp
  • A to G, chromosome 7 at 23,417,708 bp
  • C to T, chromosome 7 at 29,705,624 bp
  • T to C, chromosome 7 at 30,360,251 bp
  • C to A, chromosome 7 at 34,371,045 bp
  • A to T, chromosome 7 at 40,993,056 bp
  • T to C, chromosome 7 at 100,930,743 bp
  • T to A, chromosome 7 at 104,383,481 bp
  • T to A, chromosome 7 at 120,668,401 bp
  • C to T, chromosome 7 at 126,291,835 bp
  • T to C, chromosome 8 at 10,376,285 bp
  • G to C, chromosome 8 at 13,798,338 bp
  • A to C, chromosome 8 at 62,076,284 bp
  • T to C, chromosome 9 at 7,579,009 bp
  • T to C, chromosome 9 at 15,291,996 bp
  • C to T, chromosome 9 at 39,238,429 bp
  • A to T, chromosome 10 at 10,550,867 bp
  • G to A, chromosome 10 at 18,589,666 bp
  • A to G, chromosome 10 at 24,795,716 bp
  • A to G, chromosome 10 at 25,504,192 bp
  • G to A, chromosome 10 at 81,586,314 bp
  • G to T, chromosome 10 at 108,230,553 bp
  • A to T, chromosome 11 at 49,470,331 bp
  • T to A, chromosome 11 at 73,204,031 bp
  • A to G, chromosome 12 at 32,195,673 bp
  • A to T, chromosome 12 at 54,930,312 bp
  • T to C, chromosome 13 at 30,856,797 bp
  • T to C, chromosome 13 at 47,041,489 bp
  • T to C, chromosome 13 at 53,113,217 bp
  • T to C, chromosome 13 at 67,293,314 bp
  • T to A, chromosome 13 at 70,768,692 bp
  • C to T, chromosome 13 at 90,936,586 bp
  • C to T, chromosome 14 at 20,653,611 bp
  • T to A, chromosome 14 at 31,303,907 bp
  • A to G, chromosome 14 at 52,000,993 bp
  • A to G, chromosome 15 at 90,997,541 bp
  • A to T, chromosome 16 at 20,193,216 bp
  • G to A, chromosome 16 at 92,321,187 bp
  • A to T, chromosome 17 at 20,113,626 bp
  • A to G, chromosome 17 at 24,596,958 bp
  • A to G, chromosome 17 at 25,245,229 bp
  • T to A, chromosome 18 at 19,981,172 bp
  • A to T, chromosome 18 at 53,194,522 bp
  • G to T, chromosome 19 at 5,907,127 bp
  • A to G, chromosome 19 at 7,467,880 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0826 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039006-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.