Strain Name:
C57BL/6J-MtgxR0841Btlr/Mmmh
Stock Number:
039020-MU
Citation ID:
RRID:MMRRC_039020-MU
Other Names:
R0841 (G1), C57BL/6J-MtgxR0841Btlr
Major Collection:

Gene Information

Ldb2
Name: LIM domain binding 2
Synonyms: CLIM-1a, CLP-36, CLIM-1b, Ldb3, CLIM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16826
HGNC: HGNC:6533
Homologene: 989
Slc17a6
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
Synonyms: 2900073D12Rik, VGLUT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 140919
Homologene: 121617
Zfp7
Name: zinc finger protein 7
Synonyms: mszf73-2, Krox-2, KRAB7, KRAB20, Zfp86-rs1, Zfp65, Zfp-7, Zfp80
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223669
VEGA: 15
Homologene: 20729
Inpp5k
Name: inositol polyphosphate 5-phosphatase K
Synonyms: putative PI-5-phosphatase, PI-5-phosphatase related, Pps, C62
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19062
Homologene: 75059
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: eIF4GII, G1-419-52, repro8, 4930523M17Rik, 1500002J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Plxna1
Name: plexin A1
Synonyms: 2600013D04Rik, NOV, Plxn1, PlexA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18844
HGNC: HGNC:9099
Homologene: 56426
Smg1
Name: SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
Synonyms: 5430435M13Rik, C130002K18Rik, 2610207I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233789
Homologene: 56697
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, D4Abb1e, 4833432B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100019
Homologene: 39689
Snapc1
Name: small nuclear RNA activating complex, polypeptide 1
Synonyms: 2700033G17Rik, 9630050P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 75627
VEGA: 12
Homologene: 2317
Fcho1
Name: FCH domain only 1
Synonyms: 3322402E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74015
Homologene: 22869
Slc43a2
Name: solute carrier family 43, member 2
Synonyms: 7630402D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 215113
Homologene: 17555
Otud6b
Name: OTU domain containing 6B
Synonyms: 2600013N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72201
Homologene: 6064
Fgfr2
Name: fibroblast growth factor receptor 2
Synonyms: Fgfr-2, Fgfr7, Bek, KGFRTr, svs, Fgfr-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14183
HGNC: HGNC:3689
Homologene: 22566
Tap2
Name: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms: Ham2, PSF2, Abcb3, Ham-2, MTP2, HAM2, Tap-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21355
HGNC: HGNC:44
Homologene: 37323
Kcnq1
Name: potassium voltage-gated channel, subfamily Q, member 1
Synonyms: KVLQT1, Kcna9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16535
HGNC: HGNC:6294
Homologene: 85014
Nip7
Name: NIP7, nucleolar pre-rRNA processing protein
Synonyms: 1110017C15Rik, 6330509M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 66164
Homologene: 56743
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
Homologene: 23741
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, Nesp2g, nesprin-2, syne-2, dice, Cpfl8, 6820443O06Rik, diminished cone electroretinogram
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319565
Homologene: 56700
Unc80
Name: unc-80, NALCN activator
Synonyms: C030018G13Rik, C230061B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329178
Homologene: 122243
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 329628
Homologene: 14377
Armc4
Name: armadillo repeat containing 4
Synonyms: b2b643Clo, 4930463I21Rik, b2b227.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 74934
VEGA: 18
Homologene: 9992
Eml3
Name: echinoderm microtubule associated protein like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225898
VEGA: 19
Homologene: 27044
Ctsj
Name: cathepsin J
Synonyms: Ctsp, CatRLP, CATP, rat gene/Cathepsin L-related protein, Cat P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 26898
VEGA: 13
Homologene: 137246
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: 2900083P10Rik, C230094A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237711
Homologene: 104282
Ugt3a1
Name: UDP glycosyltransferases 3 family, polypeptide A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105887
Homologene: 122787
Ugt2a1
Name: UDP glucuronosyltransferase 2 family, polypeptide A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 94215
Homologene: 136808
Glp1r
Name: glucagon-like peptide 1 receptor
Synonyms: GLP-1R, GLP1Rc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14652
VEGA: 17
HGNC: HGNC:4324
Homologene: 1558
Aass
Name: aminoadipate-semialdehyde synthase
Synonyms: LOR/SDH, Lorsdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 30956
Homologene: 4212
Trp53rkb
Name: transformation related protein 53 regulating kinase B
Synonyms: 5630401H01Rik, 4933401B08Rik, PRPK, Trp53rk, mNori-2p, Nori-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 76367
Homologene: 6042
Arhgap9
Name: Rho GTPase activating protein 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216445
VEGA: 10
Homologene: 13041
Sipa1
Name: signal-induced proliferation associated gene 1
Synonyms: SPA-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 20469
VEGA: 19
Homologene: 7940
Abi3bp
Name: ABI gene family, member 3 (NESH) binding protein
Synonyms: TARSH, eratin, D930038M13Rik, 5033411B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 320712
VEGA: 16
Homologene: 134172
Gm9956
Name: predicted gene 9956
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Vmn2r71
Name: vomeronasal 2, receptor 71
Synonyms: EG233445
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233445
Homologene: 115466
2310002L09Rik
Name: RIKEN cDNA 2310002L09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 71886
Homologene: 36448
Dnali1
Name: dynein, axonemal, light intermediate polypeptide 1
Synonyms: 1700023A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 75563
Homologene: 2586
Krtdap
Name: keratinocyte differentiation associated protein
Synonyms: Kdap, sk221
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 64661
Homologene: 52619
Hddc3
Name: HD domain containing 3
Synonyms: 1110033O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68695
Homologene: 12279
Olfr685
Name: olfactory receptor 685
Synonyms: GA_x6K02T2PBJ9-7810071-7809121, MOR37-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258160
Homologene: 66455
Etos1
Name: ectopic ossification 1
Synonyms: DD64
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
AC159637.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
Prl7a1
Name: prolactin family 7, subfamily a, member 1
Synonyms: PLP-G, PLP-E, Prlpe, Prlpg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19113
Homologene: 136279
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 66,472,088 bp
  • A to T, chromosome 1 at 150,679,607 bp
  • T to C, chromosome 2 at 166,795,510 bp
  • A to C, chromosome 3 at 38,995,998 bp
  • T to A, chromosome 4 at 14,812,532 bp
  • T to C, chromosome 4 at 32,752,032 bp
  • T to A, chromosome 4 at 73,942,749 bp
  • T to C, chromosome 4 at 125,065,547 bp
  • C to T, chromosome 4 at 138,165,818 bp
  • A to G, chromosome 5 at 44,532,674 bp
  • T to C, chromosome 5 at 87,474,789 bp
  • A to T, chromosome 6 at 23,075,811 bp
  • A to G, chromosome 6 at 89,332,204 bp
  • A to T, chromosome 7 at 30,789,550 bp
  • A to T, chromosome 7 at 51,625,315 bp
  • T to A, chromosome 7 at 80,345,653 bp
  • A to G, chromosome 7 at 85,618,541 bp
  • A to T, chromosome 7 at 105,180,854 bp
  • A to T, chromosome 7 at 118,143,301 bp
  • G to A, chromosome 7 at 130,261,905 bp
  • T to C, chromosome 7 at 130,772,007 bp
  • A to G, chromosome 7 at 143,107,452 bp
  • C to T, chromosome 8 at 71,712,560 bp
  • C to A, chromosome 8 at 107,057,375 bp
  • C to A, chromosome 10 at 56,745,328 bp
  • T to A, chromosome 10 at 56,745,329 bp
  • T to A, chromosome 10 at 127,329,639 bp
  • A to G, chromosome 11 at 29,777,430 bp
  • T to A, chromosome 11 at 75,566,989 bp
  • T to C, chromosome 11 at 75,633,459 bp
  • C to T, chromosome 12 at 73,975,006 bp
  • T to C, chromosome 12 at 76,074,435 bp
  • C to T, chromosome 12 at 93,928,280 bp
  • T to A, chromosome 13 at 27,642,410 bp
  • C to T, chromosome 13 at 61,002,543 bp
  • G to A, chromosome 15 at 9,306,128 bp
  • G to A, chromosome 15 at 76,891,504 bp
  • T to C, chromosome 16 at 56,668,276 bp
  • T to C, chromosome 17 at 30,919,432 bp
  • C to A, chromosome 17 at 34,215,940 bp
  • G to T, chromosome 18 at 7,268,436 bp
  • C to A, chromosome 19 at 5,654,807 bp
  • G to A, chromosome 19 at 8,937,685 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0841 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039020-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.